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An eikonal equation-based earthquake location method by inversion of multiple phase arrivals

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Science China Earth Sciences 2024年第6期67卷 1802-1817页

作者： Gaoyue LAO Dinghui YANG shaolin LIU Guiju DONG Wenshuai wang Kui LIU National Institute of Natural Hazards Ministry of Emergency Management of ChinaBeijing 100085China School of Earth Sciences Yunnan UniversityKunming 650091China Department of Mathematical Sciences Tsinghua UniversityBeijing 100084China School of Mathematics and Statistics Ningxia UniversityYinchuan 750021China

The precise determination of earthquake location is the fundamental basis in seismological community,and is crucial for analyzing seismic activity and performing seismic *** arrivals are generally used to practically determine earthquake ***,first-arrival traveltimes are not sensitive to focal ***,they cannot accurately constrain focal *** improve the accuracy,researchers have analyzed the depth phases of earthquake *** traveltimes of depth phases are sensitive to focal depths,and the joint inversion of depth phases and direct phases can be implemented to potentially obtain accurate earthquake ***,researchers can determine earthquake locations in layered *** layered models can only represent the first-order feature of subsurface structures,the advantages of joint inversion are not fully explored if layered models are *** resolve the issue of current joint inversions,we use the traveltimes of three seismic phases to determine earthquake locations in heterogeneous *** three seismic phases used in this study are the first P-,sPg-and *** calculate the traveltimes of the three seismic phases by solving an eikonal equation with an upwind difference scheme and use the traveltimes to determine earthquake *** verify the accuracy of the earthquake location method by the inversion of three seismic phases,we take the 2021 M_(S)6.4 Yangbi,Yunnan earthquake as an example and locate this earthquake using synthetic and real seismic *** tests demonstrate that the eikonal equation-based earthquake location method,which involves the inversion of multiple phase arrivals,can effectively improve earthquake location accuracy.

关键词： Earthquake location Eikonal equation Fast marching method Heterogeneous model

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Synthesis of Novel N-sulfonyl 4-Nitroimidazoles as Potential Antiparasitic Agent

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Synthesis of Novel N-sulfonyl 4-Nitroimidazoles as Potential...

Rapid Access to Chiralα-Alkylated Azacycles via NiH-Catalyzed Asymmetric Migratory Hydroalkylation of N-Heterocyclic Alkenes

有机合成创新—产业化的新动力——中国化学会全国第三届有机合成化学与过程学术讨论会

作者： zhang,shaolin wang,xiaoling geng,rongxia~* (Laboratory of Bioorganic & Medicinal Chemistry,School of Chemistry and Chemical Engineering, Southwest University,Chongqing 400715)

Sulfamide compounds exhibit broad-spectrum biological activities such as anti-parasitic,antibacterial,antifungal, antiviral,anti-tuberculosis properties,and various types of sulfamides drugs have extensively been used in clinic. Much attention has increasingly been paid toward the research and development of sulfonamides as drugs,and the progress is quite fast. Nitroimidazole as an important pharmacophore towards antiparasitic agents and especially hypoxic cell

关键词： anti-parasitic 4-nitroimidazole sulfamide synthesis

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CCS Chemistry 2024年第4期6卷 898-904页

作者： Changpeng Chen Wenqing Guo Deyong Qiao Junqian Zhou You wang shaolin Zhu State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic MaterialsChemistry and Biomedicine Innovation Center(ChemBIC)School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210093 School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007 Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong UniversityShanghai 200240

Asymmetric migratory hydrofunctionalization of isomeric mixtures of alkenes provides a complementary approach for the selective introduction of a functional group into a remote C(sp3)-H ***,the simultaneous control of both regio-and enantioselectivity in this migratory process is a ***α-alkyl-substituted azacycles are key motifs in pharmaceuticals,natural products,and ***,we report a NiH-catalyzed asymmetric migratory hydroalkylation process for their efficient and selective *** this process,easily available isomeric mixtures of N-heterocyclic alkenes can be directly employed as starting materials,convergently delivering a variety of enantioenrichedα-alkylated azacycles with high levels of regio-and *** synthetic utility of this transformation is demonstrated by the facile synthesis of two bioactive alkaloids,(+)-connine and(R)-*** obtained chiralα-alkylated azacycles also readily undergo diverse derivatization,such as deconstructive halogenation and ring contraction.

关键词： alkenes alkylation asymmetric catalysis isomerization nickel

Progress of GECAM Observation Research

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空间科学学报 2024年第4期44卷 668-673页

作者： wang Chenwei zhang Yanqiu XIONG shaolin LIU Jiacong TAN Wenjun XIAO Shuo XIE Shenglun XUE wangchen ZHAO Haisheng ZHAO Yi ZHENG Chao Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049 University of Chinese Academy of Sciences Beijing 100049 Guizhou Normal University Guizhou 550025 Central China Normal University Wuhan 4300795 Dezhou University Dezhou 253023

Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)is a constellation with four instruments(launch date):GECAM-A/B(10 December 2020),GECAM-C(27 July 2022)and GECAM-D(13 March 2024),which are dedicated to monitoring gamma-ray transients in *** primary science objectives of GECAM include Gamma-Ray Bursts(GRBs),Soft Gamma-ray Repeaters(SGRs),high energy counterparts of Gravitation Wave(GW)and Fast Radio Burst(FRB),Solar Flares(SFLs),as well as Terrestrial Gamma-ray Flashes(TGFs)and Terrestrial Electron Beams(TEBs).A series of observations and research have been made since the launch of GECAM-A/*** observations provide new insights into these highenergy transients,demonstrating the unique role of GECAM in the“multi-wavelength,multi-messenger”era.

关键词： GECAM Gravitational wave electromagnetic counterpart High energy transients

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Equivalent norms, Hardy-Littlewood-type theorems,and their applications

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Science China Mathematics 2024年

作者： shaolin Chen Hidetaka Hamada College of Mathematics and Statistics Hengyang Normal University Faculty of Science and Engineering Kyushu Sangyo University

The primary goal of this paper is to develop methods for investigating equivalent norms and HardyLittlewood-type theorems on Lipschitz-type spaces of analytic and complex-valued harmonic functions. First,we provide characterizations of equivalent norms on these spaces. Furthermore, we establish Hardy-Littlewoodtype theorems for complex-valued harmonic functions. These results improve and extend the main findings of Dyakonov(1997) and Dyakonov(2005). Additionally, we apply the derived equivalent norms and HardyLittlewood-type theorems to the study of composition operators between Lipschitz-type spaces.

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Recent Advances in Mn,Fe,Co,and Ni-Catalyzed Organic Reactions

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CCS Chemistry 2024年第3期6卷 537-584页

作者： Lu-Jie Li Yuli He Yunhui Yang Jun Guo Zhan Lu Congyang wang shaolin Zhu Shou-Fei Zhu College of Chemistry Nankai UniversityTianjin 300071 School of Chemistry and Chemical Engineering Nanjing UniversityNanjingJiangsu Province 210093 Institute of Chemistry Chinese Academy of Sciences and University of Chinese Academy of SciencesBeijing 100190 Department of Chemistry Zhejiang UniversityHangzhouZhejiang Province 310058

This paper reviewed the recent research progress of organic reactions catalyzed by four typical earthabundant and 3d metal catalysts:Mn,Fe,Co,and Ni complexes and mainly focused on the reactions in which these 3d metal catalysts exhibited obvious advantages over other *** mechanism that makes these 3d metal catalysts show unusual properties is another focus of this *** outlook on 3d metal complexes-catalyzed organic reactions was also considered.

关键词： Earth-abundant metal catalysts sustainable organic synthesis structure-function relationships organometallic intermediates hydrocarbon transformations

Numerical Simulation-Based Analysis of the Impact of Overloading on Segmentally Assembled Bridges

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Structural Durability & Health Monitoring 2024年第5期18卷 663-681页

作者： Donghui Ma Wenqi Wu Yuan Li Lun Zhao Yingchun Cai Pan Guo shaolin Yang Shanghai Urban Construction and Maintenance Management Co. Ltd.Shanghai200023China School of Water Conservancy and Transportation Zhengzhou UniversityZhengzhou450001China

Segmentally assembled bridges are increasinglyﬁnding engineering applications in recent years due to their unique advantages,especially as urban *** loads are one of the most important variable loads acting on bridge ***,the inﬂuence of overloaded vehicles on existing assembled bridge structures is an urgent concern at *** paper establishes theﬁnite element model of the segmentally assembled bridge based on ABAQUS software and analyzes the inﬂuence of vehicle overload on an assembled girder bridge ***,aﬁnite element model corresponding to the target bridge is established based on ABAQUS software,and the load is controlled to simulate vehicle movement in each area of the traveling zone at different ***-ond,the key cross-sections of segmental girder bridges are monitored in real time based on the force character-istics of continuous girder bridges,and they are compared with the simulation ***,a material damage ontology model is introduced,and the structural damage caused by different overloading rates is compared and *** show that theﬁnite element modeling method is accurate by comparing with on-site measured data,and it is suitable for the numerical simulation of segmental girder bridges;Dynamic sensors installed at 1/4L,1/2L,and 3/4L of the segmental girder main beams could be used to identify the dynamic response of segmental girder bridges;The bottom plate of the segmental girder bridge is mostly damaged at the position where the length of the precast beam section changes and the midspan *** the increase in load,damage in the direction of the bridge develops faster than that in the direction of the transverse ***ﬁndings of this study can guide maintenance departments in the management and maintenance of bridges and vehicles.

关键词： Segmentally assembled bridge dynamic response moving loads overloading structural damage ﬁnite element analysis

Codelivery of anti-CD47 antibody and chlorin e6 using a dual pH-sensitive nanodrug for photodynamic immunotherapy of osteosarcoma

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Oncology Research 2024年第4期32卷 691-702页

作者： JIJIE XIAO HONG XIAO YUJUN CAI JIANWEI LIAO JUE LIU LIN YAO shaolin LI Department of Radiology The Fifth Affiliated Hospital of Sun Yat-Sen UniversityZhuhai510900China Department of Ultrasound The Third Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou528405China PCFM Lab of Ministry of Education School of Materials Science and EngineeringGuangzhou510275China

Osteosarcoma is a malignant tumor originating from bone tissue that progresses rapidly and has a poor patient *** has shown great potential in the treatment of ***,the immunosuppressive microenvironment severely limits the efficacy of osteosarcoma *** dual pH-sensitive nanocarrier has emerged as an effective antitumor drug delivery system that can selectively release drugs into the acidic tumor ***,we prepared a dual pH-sensitive nanocarrier,loaded with the photosensitizer Chlorin e6(Ce6)and CD47 monoclonal antibodies(aCD47),to deliver synergistic photodynamic and immunotherapy of *** laser irradiation,Ce6 can generate reactive oxygen species(ROS)to kill cancer cells directly and induces immunogenic tumor cell death(ICD),which further facilitates the dendritic cell maturation induced by blockade of CD47 by ***,both calreticulin released during ICD and CD47 blockade can accelerate phagocytosis of tumor cells by macrophages,promote antigen presentation,and eventually induce T lymphocyte-mediated antitumor ***,the dual pH-sensitive nanodrug loaded with Ce6 and aCD47 showed excellent immune-activating and anti-tumor effects in osteosarcoma,which may lay the theoretical foundation for a novel combination model of osteosarcoma treatment.

关键词： Immunotherapy Osteosarcoma Nanodrug Photodynamic therapy CD47

Space advanced technology demonstration satellite

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Science China(Technological Sciences) 2024年第1期67卷 240-258页

作者： zhang XiaoFeng CHEN Wen ZHU XiaoCheng MENG Na HE Junwang BI XingZi zhang YongHe SHI Qi LI Fei LIU Rui FENG ZhengGong LIU Liu LI JinSong WU HaiChen XU DongXiao LI TaiJie HUANG JiangJiang LIU Shuo LI TianTong YU XianSheng GAO Yang ZHOU Heng BAN HanYu zhang YanLi zhang YueTing YANG YingQuan HE Tao DUAN XuLiang CHEN Xin wang YaMin SUN AnTai zhang KuoXiang SUN Ying wang YaoBin FAN ChengCheng XIONG shaolin LI XinQiao WEN XiangYang LING ZhiXing SUN XiaoJin zhang Chen BAI XianYong wang ZhanShan DENG YuanYong TIAN Hui YANG JianFeng XUE HongBo SANG Peng LIU JinGuo ZHENG HuiLong ZHU Xiang HE JianWu LI Hui XU LuXiang XU ShuYan CHEN WenWu LIU ZhenDong wang ZhaoLi MAO XiangLong GAO Rong LI ZongXuan DING GuoPeng wang XinYu DOU RunJiang WENG LuBin LUO Hao wang YaPing LIANG XianFeng FANG ZiRuo Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 201203China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China National Astronomical Observatory of China Beijing 100101China Shanghai Institute of Technical Physics Chinese Academy of SciencesShanghai 200083China Institute of Precision Optical Engineering School of Physics Science and EngineeringTongji UniversityShanghai 200092China School of Earth and Space Sciences Peking UniversityBeijing 100871China Xi’an Institute of Optics and Precision Mechanics Chinese Academy of SciencesXi’an 710119China National Space Science Center Chinese Academy of SciencesBeijing 100190China Shenyang Institute of Automation Chinese Academy of SciencesShenyang 110016China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100190China Institute of Mechanics Chinese Academy of SciencesBeijing 100190China Shanghai Institute of Organic Chemistry Chinese Academy of SciencesShanghai 200032China Hangzhou Institute for Advanced Study University of Chinese Academy of SciencesHangzhou 310024China Nanyang Technological University Singapore 569830Singapore Dalian Institute of Chemical Physics Chinese Academy of SciencesDalian 116023China Technical Institute of Physics and Chemistry Chinese Academy of SciencesBeijing 100049China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Institute of Semiconductors Chinese Academy of SciencesBeijing 100083China Institute of Automation Chinese Academy of SciencesBeijing 100190China School of Aeronautics and Astronautics Zhejiang UniversityHangzhou 310058China

The Space Advanced Technology demonstration satellite(SATech-01),a mission for low-cost space science and new technology experiments,organized by Chinese Academy of Sciences(CAS),was successfully launched into a Sun-synchronous orbit at an altitude of~500 km on July 27,2022,from the Jiuquan Satellite Launch *** as an experimental platform for space science exploration and the demonstration of advanced common technologies in orbit,SATech-01 is equipped with 16 experimental payloads,including the solar upper transition region imager(SUTRI),the lobster eye imager for astronomy(LEIA),the high energy burst searcher(HEBS),and a High Precision Magnetic Field Measurement System based on a CPT Magnetometer(CPT).It also incorporates an imager with freeform optics,an integrated thermal imaging sensor,and a multi-functional integrated imager,*** paper provides an overview of SATech-01,including a technical description of the satellite and its scientific payloads,along with their on-orbit performance.

关键词： SATech-01 spacecraft design scientific instruments on-orbit performance

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