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Postprocedural Outcomes and Risk Factors for Arrhythmias Following Transcatheter Closure of Congenital Perimembranous Ventricular Septal Defect： A Single-center Retrospective Study

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Chinese Medical Journal 2017年第5期130卷 516-521页

作者： Li-jian Zhao Bo Han jian-jun zhang Ying-Chun Yi Dian-Dong jiang jian-Li Lyu Department of Pediatric Cardiology Shandong Provincial Hospital Affiliated to Shandong University Jinan Shandong 250021 China

Background： Currently, transcatheter closure of perimembranous ventricular septal defect （pmVSD） is a widely accepted therapeutic modality. However, arrhythmias, especially postprocedural heart blocks, are a concern and outcomes are not very clear. This study explored the outcomes and risk factors of arrhythmias associated with transcatheter device closure ofpmVSD. Methods： A total of 395 patients diagnosed with pmVSD who successfully underwent transcatheter intervention between January 2010 and December 2015 in our center were retrospectively reviewed. Electrocardiographic data before and after the procedure were collected and analyzed. We first evaluated the potential risk factors including gender, age, weight, inlet and outlet diameters of defect, subaortic rim length, occluder size, corrected occluder size into body surface area, fluoroscopy time, presence of aneurysm, and deployment position. We compared the potential risk factors between arrhythmia and nonarrhythmia groups using univariate analysis, followed by logistic analysis for independent risk factors. Results： Various arrhythmias were detected in 95 cases （24.1%） following transcatheter closure procedure. Logistic regression analysis revealed that eccentric （odds ratio [OR] 2.9, 95% confidence interval [（CI]： 1.2-7.2） and large occluders （OR 2.0, 95% （.7： 1.6-2.5）, as well as long fluoroscopy time （OR 1.1, 95% CI： 1.1-1.2）, were correlated with postprocedural arrhythmia. During 35.5 months （range： 9-80 months） of follow-up, most of the patients （74 out of 95） reverted to normal heart rhythm. Conclusions： The mid-term outcome of patients with arrhythmias after transcatheter closure of pmVSD was satisfactory as most of the patients recovered normal rhythm. Eccentric, large device and long fluoroscopy time increase the risk of arrhythmias after transcatheter closure of pmVSD.

关键词： Arrhvthmia Occluder Outcomes Percutaneous Closure Perimembranous Ventricular Septal Defect Risk Factors

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The exploration and practice of low-altitude airspace flight service and traffic management in China

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Green Energy and Intelligent Transportation 2024年第2期3卷 1-8页

作者： Xiangmin Guan Hongxia Shi Dongsong Xu Binhua zhang jian Wei jun Chen CAAC Key Laboratory of General Aviation Operation Department of General AviationCivil Aviation Management Institute of ChinaBeijing 100102China Research Institute of Civil Aviation Regulations and Standardization China Academy of Civil Aviation Science and TechnologyBeijing 100028China Department of Technology Platform Phoenix Wings Technology(Shen zhen)Co.LtdShenZhen 518054China Shenzhen Highgreat Innovation Technology Development Co. Ltd dShenzhen 518000China School of Engineering and Materials Science Queen Mary University of LondonLondonE14NSUK

Due to the inherent nature of being highly digitalized,networked and intelligent,Unmanned Aerial System(UAS)operations pose a huge challenge to traditional aviation regulation and technical *** to keep safe,efficient and integrated operation for different Airspace users has become a pressing issue faced by civil aviation around the *** paper focuses on the main operational scenarios and characteristics of unmanned aviation development in *** operational characteristics and associated challenges due to diverse low-altitude users are analyzed,including operation concepts,UAS traffic management,technological test and verification,and *** light on the practices in Europe and the United States,this paper summarizes China's practices and progress in low-altitude operations management,and analyzes future technological development needs and trends,as well as feasible implementation pathways and measures based on actual needs.

关键词： UAS Low-altitude airspace UAS traffic management Exploration and practice

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Physician-dependent diagnosis delay in Crohn's disease:A pseudoproposition or not?

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World Journal of Gastroenterology 2024年第38期30卷 4242-4245页

作者： Yan Zeng jun-Wen zhang jian Yang Department of Psychology The Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China Department of Gastroenterology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

The challenge of diagnosis delay in inflammatory bowel disease(IBD)has emerged as a significant concern for both patients and healthcare *** widely accepted notion that there is an extended time frame from the onset of symptoms to the definitive diagnosis is often attributed to the heterogeneity of IBD and the non-specificity of clinical *** to patients with Crohn’s disease,the issue of delayed diagnosis appears to be more pronounced across different regions *** intricate interplay of real-world factors has led to debates regarding the primary contributors to these diagnostic *** a comparison solely between patients and physicians and implicating the latter as the predominant influence factor may fall into a simplistic either-or logical trap that may obscure the *** letter,grounded in published evidence,explores areas for improvement in a forthcoming paper within the field,hoping to pinpoint the culprit behind the diagnosis delay issue for IBD patients rather than simply attributing it to so-called“physician-dependent factors”.Our objective is to motivate healthcare providers and policymakers in relevant fields to reflect on strategies for addressing this problem to reduce diagnostic delays and enhance patient outcomes.

关键词： Inflammatory bowel disease Crohn’s disease Diagnosis delay Influencing factors Culprit

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Towards adaptable synchrotron image restoration pipeline

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NUCLEAR SCIENCE AND TECHNIQUES 2024年第10期35卷 1-13页

作者： Li, Chun Bi, Xiao-Xue zhang, Yu-jun zhang, Zhen Wang, Li-Wen Zhuang, jian Chen, Dong-Liang Dong, Yu-Hui zhang, Yi Chinese Acad Sci Inst High Energy Phys Beijing Synchrotron Radiat Facil Beijing 100049 Peoples R China Spallat Neutron Source Sci Ctr Dongguan 523803 Peoples R China Univ Chinese Acad Sci Beijing 100049 Peoples R China Univ Sci & Technol China Natl Synchrotron Radiat Lab Hefei 230029 Peoples R China

Synchrotron microscopic data commonly suffer from poor image quality with degraded resolution incurred by instrumentation defects or experimental conditions. Image restoration methods are often applied to recover the reduced resolution, providing improved image details that can greatly facilitate scientific discovery. Among these methods, deconvolution techniques are straightforward, yet either require known prior information or struggle to tackle large experimental data. Deep learning (DL)-based super-resolution (SR) methods handle large data well, however data scarcity and model generalizability are problematic. In addition, current image restoration methods are mostly offline and inefficient for many beamlines where high data volumes and data complexity issues are encountered. To overcome these limitations, an online image-restoration pipeline that adaptably selects suitable algorithms and models from a method repertoire is promising. In this study, using both deconvolution and pretrained DL-based SR models, we show that different restoration efficacies can be achieved on different types of synchrotron experimental data. We describe the necessity, feasibility, and significance of constructing such an image-restoration pipeline for future synchrotron experiments.

关键词： Synchrotron Deconvolution Deep learning Super-resolution Pipeline SUPERRESOLUTION REGULARIZATION DECONVOLUTION SOFTWARE

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维持性血液透析患者躯体衰弱测量工具及影响因素的研究进展

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中国血液净化 2024年第8期23卷 612-615页

作者：朱铮炜张建军曹惠婷孙诣深陶幸娟上海交通大学医学院上海200025 上海交通大学护理学院上海200025

维持性血液透析患者往往合并衰弱,而衰弱可导致多种临床不良结局,给患者的生活质量和生命安全带来极大威胁。衰弱是一种复杂的综合征,通常涵盖躯体、认知和社会等方面,这三方面是相互联系、相互作用、相互影响的。躯体衰弱发病率较高且... 详细信息

维持性血液透析患者往往合并衰弱,而衰弱可导致多种临床不良结局,给患者的生活质量和生命安全带来极大威胁。衰弱是一种复杂的综合征,通常涵盖躯体、认知和社会等方面,这三方面是相互联系、相互作用、相互影响的。躯体衰弱发病率较高且通常会引起认知衰弱和社会衰弱,若能在早期及时评估并进行干预,可减轻或扭转病情发展。因此,本文对躯体衰弱的评估工具、影响因素等进行综述,以期为我国维持性血液透析患者开展衰弱的干预治疗提供借鉴。

关键词：维持性血液透析躯体衰弱评估影响因素

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Grain boundary-induced drastic sensing performance enhancement of Fe_(2)O_(3) gas sensors for acetone

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Rare Metals 2024年第9期43卷 4412-4424页

作者： Tian-jun Hu Yi-Fan Li Yu-Zhu Tian Ying Wang Ya-Ru Chen jun-Ming zhang Er-Gui Luo jian-Feng Jia Key Laboratory of Magnetic Molecules&Magnetic Information Materials Ministry of Education School of Chemical and Material ScienceShanxi Normal UniversityTaiyuan 030032China

Exploring the structure-activity relationship between the performance of gas sensors and the structure of semiconductor metal oxide(SMO)nanomaterials is crucial for understanding and designing gas-sensing materials and overcoming the application limitations of SMO-based gas *** of a single SMO microstructure provides a promising solution to address this scientific problem due to its controllable *** this study,we control the grain boundary(GB)density of Fe_(2)O_(3)nanomaterials using a simple solvothermal *** have similar chemical compositions and crystal phases,providing an ideal platform for studying the influence of the GB density on the gas-sensing ***-sensing tests showed that the Fe_(2)O_(3)-1 sensor with medium GB density and the Fe_(2)O_(3)-2 sensor with high GB density had higher sensitivity and selectivity than the Fe_(2)O_(3)-0 sensors with low GB density before reaching the optimal operating ***,when the GB density increased,the response to acetone decreased slightly,whereas the optimal operating temperature *** work highlights the unique performance of the GB density in enhancing the gas sensitivity of a single SMO.

关键词： Semiconductor metal oxide(SMO) Grain boundary(GB)density Oxygen adsorption Charge transfer Gas sensors

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Al吸附在Pt,Ir和Au的(111)面的低覆盖度研究

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物理学报 2010年第6期59卷 4143-4149页

作者：张建军张红四川大学物理科学与技术学院成都610065

应用密度泛函理论,系统研究了Al原子在Pt(111),Ir(111)和Au(111)表面的桥位、顶位、三重面心立方(fcc)洞位和六角密排(hcp)洞位这四个典型位置的吸附情况.主要计算了三吸附体系的几何结构、平均结合能和差分电荷密度,并系统讨论了相关... 详细信息

应用密度泛函理论,系统研究了Al原子在Pt(111),Ir(111)和Au(111)表面的桥位、顶位、三重面心立方(fcc)洞位和六角密排(hcp)洞位这四个典型位置的吸附情况.主要计算了三吸附体系的几何结构、平均结合能和差分电荷密度,并系统讨论了相关原子的密立根电荷布居数和投影态密度.研究发现,对于Pt(111)和Ir(111)表面,Al原子在hcp洞位最稳定,但是对于Au(111)表面,Al原子在fcc洞位最稳定.

关键词：吸附密度泛函理论结合能电子结构

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Psychological distress, family functioning, and social support in family caregivers for patients with dementia in the mainland of China

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Chinese Medical Journal 2013年第18期126卷 3417-3421页

作者： zhang Hong XIONG Rong-hong Sara Hujiken zhang jun-jian zhang Xiao-qin Department of Neurology Zhongnan Hospital of Wuhan University Wuhan Hubei 430071 China Teaching and Research Section of Neuropsychiatry Zhongnan Hospital of Wuhan University Wuhan Hubei 430071 China Department of Neurology Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine Urumqi Xinjiang 830000 China

Background Dementia is a chronic progressive disease seriously affecting the patient＇s daily life and working skills and may cause the patient disability and dependence. Thus, caring for dementia patients inevitably falls on families in the mainland of China. Unfortunately, there are rarely enough reports available about mental health and social support in family caregivers for domestic dementia patients. This study aimed to investigate the changes in psychological status and social support in domestic dementia family caregivers and hope the government and relevant departments pay more attention to the family caregiver＇s psychological change, which may be better for dementia patients. Methods Fifty-eight immediate family caregivers （family group） for dementia patients, including 21 Alzheimer＇s disease （AD） and 37 vascular dementia inpatients, were recruited for interview. Fifty-eight age- and sex-matched normal volunteers （control group） were also interviewed in the same period. The psychiatric distress was assessed by the Symptom Checklist 90 （SCL-90）, family functioning was assessed by the Family Assessment Device （FAD）, and the social support was assessed by the Multidimensional Scale of Perceived Social Support （MSPSS）. Group differences were analyzed using unpaired t test for comparison of SCL-90, FAD, and MSPSS mean scores. Pearson＇s correlation coefficient was used to find the association between the various dimensions of FAD and the social support from dementia family caregivers. Results Except phobic anxiety dimension, the other dimensions of SCL-90 mean scores were significantly higher in the family group than those in the control group （P 〈0.05）. In the family group, except affective involvement dimension, the other dimensions of FAD mean scores were within the scope of unhealthy family functioning. Significant differences in problem solving, communication, roles, affective responsiveness, behavioral control, general functioning, and the total MSPSS mean

关键词： dementia family caregivers psychiatric distress familyfunctioning social support

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Regulating metal-acid double site balance on mesoporous SiO2-Al2O3 composite oxide for supercritical n-decane cracking

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Petroleum Science 2024年第4期21卷 2881-2891页

作者： Liu-Ling Chen jun zhang Chun-Guang Li Li-Qun Fei Bo Wang Chen-Qi zhang Yi Jiao jian-Li Wang Institute of New Energy and Low-Carbon Technology Sichuan University Engineering Research Center of Combustion and Cooling for Aerospace Power Ministry of Education School of Chemical Engineering Sichuan University State Key Laboratory of Industrial Vent Gas Reuse Southwest Institute of Chemical Co. Ltd Science and Technology on Scramjet Laboratory Beijing Power Machinery Research Institute

The balance between metal and acid sites directly affects the preparation of high-performance cracking catalysts with high heat sink and low ***,how to control acid-metal sites balance and its relationship with cracking performance are reported *** this work,a series of Pt/Al2O3-SiO2dual sites catalysts with different metal to acid active sites ratio(CM/CSA) were constructed by ethanolassisted impregnation method and the impact on n-decane cracking under supercritical conditions was systematically and deeply *** results showed that the conversion and carbon deposition increased gradually with varied CM/CSAand reached the balance at CM/CSAof *** proper ratio CM/CSA（0.13） can balance the deep dehydrogenation coking over metal active sites and high heat sink of cracking over acid active sites,the chemical heat sink reaches amazing 1.75 MJ/kg and carbon deposition is only22.03 mg/cm2at 750℃.Meanwhile,the few metal sites at low CM/CSAand the few strong acid sites at high CM/CSAare the main factors limiting the cracking *** CM/CSAlimit the activation of C-H bond and deep dehydrogenation of coking precursor,resulting in relative low cracking activity and carbon deposition,while high CM/CSAlimit the activation of C-C bond and increase the deep *** this contribution,design and construction of metal-acid dual sites can not only provide the technical solution for the preparation of high heat sink and low coking cracking catalyst,but also deepen the understanding of the cracking path of hydrocarbon fuel.

关键词： Metal-acid dual sites balance Catalytic cracking Hydrocarbon fuels Chemical heat sink Carbon deposition

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Research on the solid particle erosion wear of pipe steel for hydraulic fracturing based on experiments and numerical simulations

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Petroleum Science 2024年第4期21卷 2779-2792页

作者： Si-Qi Yang jian-Chun Fan Ming-Tao Liu De-Ning Li jun-Liang Li Li-Hong Han jian-jun Wang Shang-Yu Yang Si-Wei Dai Lai-Bin zhang State Key Laboratory of Oil and Gas Equipment CNPC Tubular Goods Research Institute Key Laboratory of Oil and Gas Safety and Emergency Technology China University of Petroleum Oil Production Technology Research Institute of Liaohe Oilfield Company Tianjin Gas Storage Branch PetroChina Dagang Oilfield Company Petroleum Production Engineering Research Institute Daqing Oilfield Company

Erosion wear is a common failure mode in the oil and gas industry. In the hydraulic fracturing, the fracturing pipes are not only in high-pressure working environment, but also suffer from the impact of the high-speed solid particles in the fracturing fluid. Beneath such complex conditions, the vulnerable components of the pipe system are prone to perforation or even burst accidents, which has become one of the most serious risks at the fracturing site. Unfortunately, it is not yet fully understood the erosion mechanism of pipe steel for hydraulic fracturing. Therefore, this article provides a detailed analysis of the erosion behavior of fracturing pipes under complex working conditions based on experiments and numerical simulations. Firstly, we conducted erosion experiments on AISI 4135 steel for fracturing pipes to investigate the erosion characteristics of the material. The effects of impact angle, flow velocity and applied stress on erosion wear were comprehensively considered. Then a particle impact dynamic model of erosion wear was developed based on the experimental parameters, and the evolution process of particle erosion under different impact angles, impact velocities and applied stress was analyzed. By combining the erosion characteristics, the micro-structure of the eroded area, and the micro-mechanics of erosion damage, the erosion mechanism of pipe steel under fracturing conditions was studied in detail for the first time. Under high-pressure operating conditions, it was demonstrated through experiments and numerical simulations that the size of the micro-defects in the eroded area increased as the applied stress increased, resulting in more severe erosion wear of fracturing pipes.

关键词： Erosion wear Applied stress Particle impact dynamics Erosion mechanism

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