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Hydrogen storage thermodynamics and kinetics of as-cast Ce-Mg-Ni-based alloy

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Journal of Iron and Steel Research International 2024年第3期31卷 752-766页

作者： Yan Qi Xin zhang Jun Li Dong-liang Zhao Shi-hai Guo Yang-huan zhang Department of Functional Material Research Central Iron and Steel Research InstituteBeijing 100081China China Rare Earth New Material(Weishan)Co..Ltd. Jining 277600ShandongChina Collaborative Innovation Center of Integrated Exploitation of Bayan Obo Multi-Metal Resources Inner Mongolia University of Science and TechnologyBaotou 014010Inner MongoliaChina

The reaction kinetics of alloys based on magnesium are known to be greatly improved by the partial substitution of Mg with rare earths and transition metals,particularly *** enhanced superficial hydrogen dissociation rate,the weakened Mg-H bond and the lower activation energy following element replacement are thought to be related to the better *** experimental alloys Ce5Mg_(95-x)Ni_(x)(x=5,10,15)were smelted by the vacuum induction *** phase transformation and structural evolution of experimental alloys before and after reaction with hydrogen were char-acterized by X-ray diffraction,scanning electron microscopy and transmission electron *** cast specimens contain CeMg_(12),Mg and Mg_(2)Ni phases,and the increase in Ni content results in an obvious growth of Mg_(2)Ni *** isothermal and non-isothermal hydrogenation and dehydrogenation kinetics of the experimental specimens were investi-gated using the Sievert apparatus,differential scanning calorimetry and thermal gravimetric *** activation energy may be calculated using the Arrhenius and Kissinger *** experimental alloys have been shown to have good activation properties,with a reversible hydriding and dehydriding capacities of around 5.0 wt.%in the first *** initial dehydrogenation temperature of MgH_(2) decreases from 557.5 to 537.7 K with changing Ni content from 5 to 15 at.%.The dehydrogenation activation energy also reduces from 77.09 to 62.96 kJ/mol,which explains the improved hydrogen storage performance caused by Ni *** can be shown that the impact of Ni on the decomposition enthalpy of MgH_(2) is quite modest,with the absolute enthalpy(ΔHr)only decreasing from 78.48 to 76.15 kJ/mol.

关键词： Mg-based alloy Ni content Hydrogen storage kinetics Thermodynamic property Activation energy

Analysis of metabolic characteristics of metabolic syndrome in elderly patients with gastric cancer by non-targeted metabolomics

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2419-2428页

作者： huan zhang Wen-Bing Shen Lin Chen Medical School of Chinese PLA Chinese PLA General HospitalBeijing 100853China Department of Gastrointestinal Surgery Shanghai Sixth People’s HospitalShanghai 250063China Department of General Surgery The First Medical Center of Chinese PLA General HospitalBeijing 100853China

BACKGROUND The relationship between metabolic syndrome(MetS)and gastric cancer(GC),which is a common metabolic disease,has attracted much ***,the specific metabolic characteristics of MetS in elderly patients with GC remain *** To investigate the differentially abundant metabolites and metabolic pathways between preoperative frailty and MetS in elderly patients with GC based on nontargeted metabolomics *** In this study,125 patients with nonfrail nonmeal GC were selected as the control group,and 50 patients with GC in the frail group were selected as the frail ***-five patients with GC combined with MetS alone were included in the MetS group,and 50 patients with GC combined with MetS were included in the MetS *** metabolomics techniques were used to measure plasma metabolite levels by ultrahigh-performance liquid chromatography-mass *** statistical analysis was performed by principal component analysis,orthogonal partial least squares,pattern recognition analysis,cluster analysis,and metabolic pathway *** A total of 125 different metabolites,including amino acids,glycerophospholipids,sphingolipids,fatty acids,sugars,nucleosides and nucleotides,and acidic compounds,were identified via nontargeted metabolomics *** with those in the control group,there were 41,32,and 52 different metabolites in the MetS group,the debilitated group,and the combined group,*** metabolites were significantly increased in the MetS *** the weak group,amino acids and most glycerol phospholipid metabolites decreased significantly,and fatty acids and sphingosine increased *** combined group was characterized by significantly increased levels of nucleotide metabolites and acidic *** alanine,aspartic acid,and glutamate metabolic pathways were obviously enriched in the asthenic group,and the glycerol and phospholipid metabolic pathways were obv

关键词： Nervous breakdown Metabolic syndrome Elderly individuals Gastric cancer Nontargeted metabolomics

A new abdominal drainage tube fixation method for 3-port laparoscopic cholecystectomy improves patients’postoperative quality of life

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第3期7卷 107-112页

作者： Fenghua zhang Lin Lin huan zhang Jinghua Liu Rui Wang Department of Operating Room Linyi People’s HospitalLinyi 276000China Department of Health Care Linyi People’s HospitalLinyi 276000China Department of Hepatobiliary Surgery Guangzhou University of Chinese MedicineGuangzhou 510006China Department of Hepatobiliary Surgery and Minimally Invasive Institute of Digestive Surgery Linyi People’s HospitalLinyi 276000China

Objective Laparoscopic surgery has become a routine general surgery with many advantages,such as alleviating abdominal ***,postoperative pain caused by abdominal drainage tubes has attracted little attention from medical *** aim of this study was to explore the influence of a new abdominal drainage tube fixation method for 3-port laparoscopic cholecystectomy(LC)on patients’postoperative quality of *** Patients who underwent 3-port LC with abdominal drainage tubes in the Department of Hepatobiliary Surgery of Linyi People’s Hospital from March 1,2023 to October 31,2023 due to gallstones with chronic cholecystitis were selected for this *** patients were randomly divided into an experimental group and a control *** the experimental group,the new abdominal drainage tube fixation method was used,while in the control group,the traditional method was ***,the quality of life of patient in terms of pain,activity,recovery time,and mental health status was *** exudate around the patient’s drainage tube was collected for bacterial culture and *** A total of 139 patients were randomly divided into an experimental group(70 patients)and a control group(69 patients).The patients’baseline characteristics were not significantly *** patients in the experimental group had better outcomes in quality of life,with higher pain scores(24.03±2.37 vs.15.48±2.29,p<0.001)and activity scores(20.57±1.78 vs.14.13±1.43,p<0.001),and a shorter postoperative recovery time(2.36±0.68 d vs.2.96±1.34 d,p<0.001).The same results were shown in linear regression analysis scores of the 2 *** positive rate of bacterial culture in the exudate around the patient’s drainage tube in the experimental group was significantly lower than that in the control group(12.9%vs.43.5%,p<0.001);and furthermore,the positive rate of conditional pathogenic bacteria was even lower(7.1%vs.33.3%,p<0.001)in the experimental group than in the contro

关键词： Abdominal drainage tube Surgical site infection Quality of life Fixation method Laparoscopic cholecystectomy

Bibliometric study of sepsis-associated liver injury from 2000 to 2023

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World Journal of Gastroenterology 2024年第30期30卷 3609-3624页

作者： Zheng zhang Xiao-Jiao Tan Hai-Qing Shi huan zhang Jian-Bo Li Xue-Lian Liao Department of Critical Care Medicine West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Critical Care Medicine West China Tianfu Hospital of Sichuan UniversityChengdu 610200Sichuan ProvinceChina

BACKGROUND Sepsis-associated liver injury(SLI)is a severe and prevalent complication of *** To explore the literature on SLI via a bibliometric *** Reviews and articles correlated with SLI published from January 1,2000 to October 28,2023 were searched from the Web of Science Core ***,the searched data were analyzed using VOSviewer,CiteSpace,and R *** There were 787 publications involved in this paper,comprising 745 articles and 42 ***,the United States,and Germany are the primary publication sources in this *** related to SLI primarily focused on mechanisms of pathogenesis,as evidenced by analyzing keywords,references,and the counting of original *** studies mainly involved tumor necrosis factor alpha,inflammation,oxidative stress,and nuclear factor-kappa *** There is significant growth in the research on *** investigations primarily involve basic experiments that aimed at uncovering pathogenic *** to the analyzed literature,the identified pathogenic mechanisms and potential therapeutic targets serve as the foundation for translating findings from basic research to clinical applications.

关键词： Sepsis Liver injury Bibliometric analysis Cite space VOS viewer

Pairs of thiol-substituted 1,2,4-triazole-based isomeric covalent inhibitors with tunable reactivity and selectivity

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Chinese Chemical Letters 2024年第7期35卷 329-335页

作者： Shiqi Xu Zi Ye Shuang Shang Fengge Wang huan zhang Lianguo Chen Hao Lin Chen Chen Fang Hua Chong-Jing zhang State Key Laboratory of Bioactive Substance and Function of Natural Medicines Beijing Key Laboratory of Active Substance Discovery and Druggability EvaluationInstitute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China State Key Laboratory of Bioactive Substance and Function of Natural Medicines Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study(BZ0150)Institute of Materia MedicaPeking Union Medical College and Chinese Academy of Medical SciencesBeijing 100050China The First Affiliated Hospital of Wenzhou Medical University Wenzhou 325000China

Covalent bioactive compounds are successfully used in clinic and attracted intense research efforts in the fundamental study as well as drug *** advantageous effects of covalent compounds compared with non-covalent ones are highly dependent on electrophilic ***,electrophilic warheads with tunable reactivity and selectivity are highly demanded in fields of medicinal chemistry and chemical ***,we report a novel electrophilic warhead,chloromethyl group activated by thiol-substituted 1,2,***,a pair of regioisomers could be simultaneously occurred in the step of alkylation during the synthesis of this unique *** is a rare example that the alkylation could simultaneously generate these two separable regioisomers of 1,2,4-triazole at the nitrogen or sulfur *** covalent-working mechanism of this new warhead is confirmed by various chemoproteomics experiments including target identification and binding site ***,the reactivity and selectivity of this new electrophilic warhead could be efficiently tuned by virtue of stereo ***,one pair of regioisomers(19S and 19X)induced distinct modes of cell *** 19S could induce apoptosis of colon cancer cells while 19X could induce both apoptosis and ***,this study provides pairs of novel electrophilic warheads that could be useful not only in supporting the design of covalent compounds for drug discovery but also in providing chemical probes for the fundamental biological study.

关键词： Electrophilic warhead Covalent inhibitor 1,2,4-Triazole Chemical proteomics GSTO1

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沙尘暴中多物理场的结构和耦合特征

Acta Mechanica Sinica 2024年第3期40卷 28-39页

作者：张欢 Center for Particle-laden Turbulence Lanzhou UniversityLanzhou730000China Key Laboratory of Mechanics on Disaster and Environment in Western China Attached to the Ministry of Education of China Lanzhou UniversityLanzhou730000China Department of Mechanics and Engineering Science College of Civil Engineering and MechanicsLanzhou UniversityLanzhou730000China

沙尘暴是典型的分散两相大气湍流,其中沙尘颗粒高度带电.虽然在单相高雷诺数湍流中已经确认存在超大尺度运动(very-large-scale motions,VLSMs),但在沙尘暴中,尤其是涉及湍动电场方面的研究还相对较少.在本文中,利用大气表面层内现场观... 详细信息

沙尘暴是典型的分散两相大气湍流,其中沙尘颗粒高度带电.虽然在单相高雷诺数湍流中已经确认存在超大尺度运动(very-large-scale motions,VLSMs),但在沙尘暴中,尤其是涉及湍动电场方面的研究还相对较少.在本文中,利用大气表面层内现场观测数据,我们证明沙尘暴的风速、直径小于10微米的沙尘颗粒浓度(PM10沙尘浓度)和电场存在大致相同大小的VLSMs.此外,我们发现这些多物理场在VLSMs尺度上具有最大的线性耦合,线性相干谱在0.5–0.8之间.通过传递熵分析,我们进一步证明风速和PM10沙尘浓度在波数k_(1)=0.002 m^(-1)处具有最大的非线性耦合,而PM10沙尘浓度和电场在k_(1)=0.15 m^(-1)处具有最大的非线性耦合,这表明风场-粉尘和粉尘-静电相互作用之间存在不同的非线性耦合行为.我们的研究结果揭示了沙尘暴中多物理场的结构和耦合特征,从而为理解复杂的分散两相湍流流动提供了关键信息.

关键词： Very-large-scale motions Electric fields Particle-laden flow Dust storms

Early Urban Planning of Harbin(1898-1917) by Russia: Impact of Colonialism and the Railway Economy on Emerging Cities in Modern Times

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China City Planning Review 2024年第3期33卷 75-87页

作者： zhang Bocheng Wang Qinglian Zhao Zhiqing zhang huan School of Architecture and Urban Planning Suzhou University of Science and TechnologySuzhouP.R.China School of Architecture Harbin Institute of TechnologyHarbinP.R.China

Harbin, a typical emerging colonial city in modern times, has drawn worldwide attention due to its quick transformation from a fishing village to a modern globalized metropolis. With Harbin and its urban planning from 1898 to 1917 as the subject of study from the perspective of planning historiography, this paper probes into the driving force behind Harbin's early modern urban development, historical phasing and characteristics of its urban planning, as well as evolution of planning and construction activities during this period. The findings reveal that Harbin's urban planning and construction activities were closely linked to Russia's political and economic interests and also reflected the political game between the powers led by Japan and Russia in the Manchurian region.

关键词： history of urban planning modern urbanization railway hub city colonialism Harbin

Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario

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Journal of Oceanology and Limnology 2024年第2期42卷 522-532页

作者： Li ZHOU Mengna LI Zhaoshan ZHONG Minxiao WANG Hao CHEN Chao LIAN Hao WANG huan zhang Lei CAO Chaolun LI Center of Deep Sea Research Institute of OceanologyChinese Academy of SciencesQingdao 266071China Laoshan Laboratory Qingdao 266237China South China Sea Institute of Oceanology Chinese Academy of SciencesGuangzhou 510301China CAS Key Laboratory of Marine Ecology and Environmental Sciences Institute of OceanologyChinese Academy of SciencesQingdao 266071China University of Chinese Academy of Sciences Beijing 100049China

Deep-sea mining activities can potentially release metals,which pose a toxicological threat to deep-sea ***,due to the remoteness and inaccessibility of the deep-sea biosphere,there is insufficient knowledge about the impact of metal exposure on its *** this study,deep-sea mussel Gigantidas platifrons,a commonly used deep-sea toxicology model organism,was exposed to manganese(100,1000μg/L)or iron(500,5000μg/L)for 7 d,*** and iron were chosen for their high levels of occurrence within deep-sea *** accumulation and a battery of biochemical biomarkers related to antioxidative stress in superoxide dismutase(SOD),catalase(CAT),malondialdehyde(MDA);immune function in alkaline phosphatase(AKP),acid phosphatase(ACP);and energy metabolism in pyruvate kinase(PK)and hexokinase(HK)were assessed in mussel *** showed that deep-sea mussel *** exhibited a high capacity to accumulate Mn/*** addition,most tested biochemical parameters were altered by metal exposure,demonstrating that metals could induce oxidative stress,suppress the immune system,and affect energy metabolism of deep-sea *** integrated biomarker response(IBR)approach indicated that the exposure to Mn/Fe had a negative impact on deep-sea mussels,and Mn demonstrated a more harmful impact on deep-sea mussels than ***,SOD and CAT biomarkers had the greatest impact on IBR values in Mn treatments,while ACP and HK were most influential for the low-and high-dose Fe groups,*** study represents the first application of the IBR approach to evaluate the toxicity of metals on deep-sea fauna and serves as a crucial framework for risk assessment of deep-sea mining-associated metal exposure.

关键词： mussel metal deep-sea mining biomarker environmental monitoring

Self-consistent and precise measurement of time-dependent radiative albedo of gold based on specially symmetrical triple-cavity Hohlraum

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Matter and Radiation at Extremes 2024年第3期9卷 57-64页

作者： Zhiyu zhang Yang Zhao Xiaoying Han Liling Li Bo Qing Lifei Hou Yulong Li YuXue zhang huan zhang Xiangming Liu Bo Deng Gang Xiong Min Lv Tuo Zhu Chengwu huang Tianming Song Yan Zhao Yingjie Li Lu zhang Xufei Xie Jiyan zhang Jiamin Yang Laser Fusion Research Center China Academy of Engineering PhysicsMianyang 621900China National Key Laboratory of Plasma Physcis Mianyang 621900China Institute of Applied Physics and Computational Mathematics Beijing 100088China

A self-consistent and precise method to determine the time-dependent radiative albedo,i.e.,the ratio of the reemission flux to the incident flux,for an indirect-drive inertial confinement fusion Hohlraum wall material is proposed.A specially designed symmetrical triple-cavity gold Hohlraum is used to create approximately constant and near-equilibrium uniform radiation with a peak temperature of 160 *** incident flux at the secondary cavity waist is obtained from flux balance analysis and from the shock velocity of a standard *** results agree well owing to the symmetrical radiation in the secondary cavity.A self-consistent and precise time-dependent radiative albedo is deduced from the reliable reemission flux and the incident flux,and the result from the shock velocity is found to have a smaller uncertainty than that from the multi-angle flux balance analysis,and also to agree well with the result of a simulation using the HYADES opacity.

关键词： precise cavity radiative