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中小博物馆高质量发展路径探索——基于河北省中小博物馆专题调研

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文物春秋 2024年第2期 51-59页

作者：熊慧彪迟畅张晓虹河北博物院河北石家庄050011

中小博物馆数量大、分布广,是博物馆事业发展的主力军,在推进实施文化惠民工程,构建均等化、广覆盖的博物馆公共文化服务体系等方面具有重要且特殊的意义。然而,中小博物馆大多零散分布在区县、乡镇中,存在体量小、客流量少、规模效应... 详细信息

中小博物馆数量大、分布广,是博物馆事业发展的主力军,在推进实施文化惠民工程,构建均等化、广覆盖的博物馆公共文化服务体系等方面具有重要且特殊的意义。然而,中小博物馆大多零散分布在区县、乡镇中,存在体量小、客流量少、规模效应差等问题,发展后劲不足,如何使中小博物馆得到均衡、充分的发展,已成为我国博物馆界关注的焦点问题。基于河北博物院2022—2023年中小博物馆专题调研成果,广泛借鉴国内外中小博物馆发展理论研究成果与优秀经验,应从找准自我定位、形成集群效应、集合多方力量三个方面探索中小博物馆高质量发展的有效路径。

关键词：中小博物馆高质量发展路径河北省专题调研

Progress in Chemical Synthesis of Peptides and Proteins

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Transactions of Tianjin University 2017年第5期23卷 401-419页

作者： Wen Hou xiaohong zhang Chuan-Fa Liu School of Life Sciences Tianjin University School of Biological Sciences Nanyang Technological University

For the proteins that cannot be expressed exactly by cell expression technology (e.g., proteins with multiple posttranslational modifications or toxic proteins), chemical synthesis is an important substitute. Given the limited peptide length offered by solid-phase peptide synthesis invented by Professor Merrifield, peptide ligation plays a key role in long peptide or protein synthesis by ligating two small peptides to a long one. Moreover, high-molecular-weight proteins must be synthesized using two or more peptide ligation steps, and sequential peptide ligation is such an efficient way. In this paper, we reviewed the development of chemical protein synthesis, including solid-phase peptide synthesis, chemical ligation, and sequential chemical ligation. © 2017, The Author(s).

关键词： Chemical modification Peptides Proteins Surgical equipment Synthesis (chemical)

我国南方桉树人工林区水体泛黑物质分子组成及形成机理

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湖泊科学 2024年第4期36卷 1069-1081,I0008页

作者：黎明杰蒋彬郭晋川潘越蒋然廖玉宏张晓红朱新海陈子龙中国科学院广州地球化学研究所有机地球化学国家重点实验室广州510640 中国科学院深地科学卓越创新中心广州510640 广西壮族自治区水利科学研究院广西壮族自治区水工程材料与结构重点实验室南宁530023 中国科学院大学北京100049 珠江水利委员会珠江水利科学研究院水利部珠江河口治理与保护重点实验室广州510640 中山大学广州510275

我国南方桉树人工林区水库在秋冬季频繁出现黑水现象。现有研究指出,桉树叶中单宁酸等物质与金属离子(如铁离子)反应产生的金属-有机质络合物是导致这一现象的主要原因。然而,目前对于桉树叶中能形成金属-有机质络合物的潜在有机质前体... 详细信息

我国南方桉树人工林区水库在秋冬季频繁出现黑水现象。现有研究指出,桉树叶中单宁酸等物质与金属离子(如铁离子)反应产生的金属-有机质络合物是导致这一现象的主要原因。然而,目前对于桉树叶中能形成金属-有机质络合物的潜在有机质前体物认识仍然有限,基于分子组成层面的桉树人工林区水库水体泛黑形成机理也尚不清楚。为此,本研究利用傅立叶变换离子回旋共振质谱(FT-ICR MS)等手段,对桉树叶浸泡液与典型桉树林区水库(金窝水库和天雹水库)水体中可溶性有机物进行了分子组成的分析。研究结果显示,桉树叶浸泡液主要由以苯三酚、没食子酸为母体的多酚类化合物及其多聚衍生物构成,其中最典型的化合物是鞣花酸(C_(14)H_(6)O_(8))。冬季水库水中鞣花酸强度远高于夏季,且表层水体高于底层水体,这表明秋冬季大量凋落的桉树叶释放出的这些芳香多酚类物质会显著促进水库黑水的形成。进一步的实验证明,鞣花酸、苯三酚和没食子酸都会与铁离子发生络合反应,生成黑色沉淀。这些结果均表明,桉树叶溶解出的芳香多酚类物质是导致水库变黑的核心因素。本研究基于分子组成层面提出了桉树人工林区水库水体泛黑形成机理,对于桉树人工林区的黑水治理和保障水库饮用水安全具有十分重要的意义。

关键词：桉树黑水芳香多酚类物质鞣花酸金属-有机质络合物傅立叶变换离子回旋共振质谱

Simultaneous Thermoluminescence and Thermally Stimulated Current in Polyamide

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Journal of Materials Science & Technology 1998年第4期14卷 357-360页

作者： Fan, Yong Wang, Xuan zhang, xiaohong Lin, Jiaqi Lei, Qingquan Harbin Univ Sci & Technol Dept Elect Mat Engn Harbin 150040 Peoples R China

The simultaneous thermoluminescence (TL) and thermally stimulated current (TSC) spectra were obtained in two types of polyamide film, such as nylons 6 and 11 under study of electron detrapping and recombination. There are three main relaxation peaks or regions, designated gamma , beta and alpha in order of increasing temperature in the TSC spectra, in contrast, a high temperature relaxation peak in TL spectra disappears. The centers of peaks of these relaxation regions are located at near 180, 230 and 310 K, respectively, deviating plus or minus 10 K. However, two anomalous phenomena were observed: firstly, a very large, short-circuited, thermally stimulated discharge current (TSDC) is up to 10** minus **8A, but reversible in direction for non-polarized nylons 6 and 11, even after several times repeatedly; secondly, there is no TL signal except for non-polarized nylon 6 film. (Edited author abstract) 11 Refs.

关键词： Polyamides

多元化延续性干预在乳腺癌术后上肢淋巴水肿康复中的应用效果

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癌症进展 2024年第1期22卷 76-78,83页

作者：张俊霞张小红汪云朋王鹏河南科技大学第一附属医院影像中心河南洛阳471000 河南科技大学第一附属医院普外科河南洛阳471000 河南科技大学第一附属医院康复中心河南洛阳471000 郑州大学护理学院社区护理教研组郑州450000

目的分析多元化延续性干预在乳腺癌患者术后上肢淋巴水肿康复中的应用效果。方法根据干预方法的不同将96例乳腺癌手术患者分为对照组(n=47)和研究组(n=49),对照组患者采用常规干预,研究组患者在对照组的基础上采用多元化延续性干预。比... 详细信息

目的分析多元化延续性干预在乳腺癌患者术后上肢淋巴水肿康复中的应用效果。方法根据干预方法的不同将96例乳腺癌手术患者分为对照组(n=47)和研究组(n=49),对照组患者采用常规干预,研究组患者在对照组的基础上采用多元化延续性干预。比较两组患者的满意度、上肢功能活动情况[臂肩手功能障碍评估表(DASH)]、上肢淋巴水肿情况。结果研究组患者的总满意度为97.96%,明显高于对照组患者的80.85%,差异有统计学意义(P﹤0.01)。干预后,两组患者DASH评分均明显低于本组干预前,研究组患者DASH评分明显低于对照组,差异均有统计学意义(P﹤0.01)。干预后,研究组患者上肢淋巴水肿情况优于对照组(P﹤0.05)。结论多元化延续性干预可减轻乳腺癌患者术后上肢淋巴水肿,促进患者上肢功能恢复,提高满意度,值得临床推广应用。

关键词：多元化延续性干预乳腺癌上肢淋巴水肿康复

Different influences of nucleating agents on crystallization behavior of polyethylene and polypropylene

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Science China Chemistry 2012年第6期55卷 1140-1147页

作者： JIANG HaiBin zhang xiaohong QIAO JinLiang College of Materials Science and Engineering Beijing University of Chemical Technology Beijing 100029 China SINOPEC Beijing Research Institute of Chemical Industry Beijing 100013 China

The crystallization behavior of polyethylene (PE) and polypropylene (PP), including the neat ones and the ones nucleated with the same nucleating agent (NA), was studied by DSC. It was found that the nucleating agent decelerated the PE nonisothermal crystallization process. NA did enhance the nucleating rates for both PE and PP, but the linear growth rate dominated the volumetric growth rate for PE, and the volumetric growth rate dominated the overall crystallization rate. That is why PE nucleated with NA had a slower overall crystallization rate than the neat one.

关键词： nucleating agent crystallization polyethylene polypropylene

TDS-1 GNSS reflectometry wind geophysical model function response to GPS block types

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Geo-Spatial Information Science 2022年第2期25卷 312-324页

作者： Fade Chen xiaohong zhang Fei Guo Jiazhu Zheng Yang Nan Mohamed Freeshah School of Geodesy and Geomatics Wuhan UniversityWuhanChina College of Civil Engineering Nanjing Forestry UniversityNanjingChina GNSS Research Center Wuhan UniversityWuhanChina State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhanChina Surveying Engineering Department Shoubra Faculty of EngineeringBenha UniversityBenhaEgypt

This paper presents the TDS-1 GNSS reflectometry wind Geophysical Model Function(GMF)response to GPS block *** observables were extracted from Delay Doppler Maps(DDMs)after taking the receiver antenna gains effects and GNSS-R geometry effects into *** the DDM is affected by GPS EffectiveIsotropic Radiated Power(EIRP),we first investigate the sensitivity of observables to the GPS ***,the observables at high SNRs are more sensitive to wind speed,but the spatial coverage at high signal to noise ratios(SNRs)is lower,while DDMs at low SNRs have the opposite *** balance the accuracy and spatial coverage,the DDM datasets are divided into two parts:high SNR(>0 dB)and low SNR(>−10 dB and≤0 dB)to develop wind ***,the influences of GPS block on wind speed retrieval both at high and low SNR is *** show that the block types have impacts on wind GMF and the use of a prior GPS block can contribute to a better wind speed retrieval both at high and low *** with ASCAT,the Root Mean Square Error(RMSE)value of wind speed retrieval at high and low SNR are 2.19 m/s and 3.13 m/s,respectively,when all TDS data are processed without distinguishing GPS block ***,if the TDS data are separately processed and used to develop wind GMF through different blocks,both the accuracy and correlation coefficient can be improved to some ***,the influence of significant height of the swell(Hs)on SNR observables is analyzed,and it is demonstrated that there is no obvious linear or nonlinear relationship between them.

关键词： Global Navigation Satellite System-Reflectometry(GNSS-R) Delay-Doppler Map(DDM) wind speed Geophysical Model Function(GMF) TechDemoSat-1(TDS-1) GPS block

Controlled 2D growth of organic semiconductor crystals by suppressing “coffee-ring” effect

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Nano Research 2020年第9期13卷 2478-2484页

作者： Wei Wang Bei Lu Wei Deng Xiujuan zhang Zhengjun Lu Di Wu Jiansheng Jie xiaohong zhang Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou 215123China Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China

Owing to enhanced charge transport efficiency arising from the ultrathin nature,two-dimensional(2D)organic semiconductor single crystals(OSSCs)are emerging as a fascinating platform for high-performance organic field-effect transistors(OFETs).However,ucoffee-ring"effect induced by an evaporation-induced convective flow near the contact line hinders the large-area growth of 2D OSSCs through a solution ***,we develop a new strategy of suppressing the"coffee-ring"effect by using an organic semiconductor:polymer blend *** the high-viscosity polymer in the organic solution,the evaporation-induced flow is remarkably weakened,ensuring the uniform molecule spreading for the 2D growth of the *** an example,wafer-scale growth of crystalline film consisting of few-layered 2,7-didecylbenzothienobenzothiophene(C10-BTBT)crystals was successfully accomplished via blade *** based on the crystalline film exhibited a maximum hole mobility up to 12.6 cm^2·V^-1·s^-1,along with an average hole mobility as high as 8.2 cm^2·V^-1·s^-*** work provides a promising strategy for the large-area growth of 2D OSSCs toward high-performance organic electronics.

关键词： two-dimensional(2D)organic semiconductor single crystals two-dimensional(2D)growth mode coffee-ring effect organic field-effect transistors

Gga3 gene-deleted C57BL/6J mice have elevated fasting blood glucose levels

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Genes & Diseases 2023年第6期10卷 2206-2209页

作者： xiaohong zhang Song Yue Dongjun Jiang Guoan zhang Jianli Liu Xuezhi Li Shandong Collaborative Innovation Center for Diagnosis Treatment and Behavioral Interventions of Mental DisordersInstitute of Mental HealthJining Medical UniversityJiningShandong 272013China Shandong Key Laboratory of Behavioral Medicine School of Mental HealthJining Medical UniversityJiningShandong 272013China Department of Pathology Weifang Medical UniversityWeifangShandong 261053China Institute of Forensic Medicine and Laboratory Medicine Jining Medical UniversityForensic Science Center of Jining Medical UniversityJiningShandong 272067China Department of Pathology Affiliated Hospital of Jining Medical UniversityJiningShandong 272000China

Diabetes mellitus(DM)is one of the most common diseases in the elderly,and among DM patients,more than 90%have type 2 DM(T2DM).The etiology of T2DM is complex and associated with risk factors such as age,genetic disposition,and *** genetic factors underlying T2DM are currently the focus of intense research,and it has been established that the susceptibility genes associated with T2DM vary among different populations.A recent longitudinal exome-wide association study in the Japanese population has identified GGA3 as a susceptible locus for T2DM.1 GGA3 is one of the Golgi-localized-ear-containing ARF binding proteins(GGAs)that function widely in the transport of Golgi-derived vesicles and in endocytic trafficking ***,although it is widely acknowledged that the control of glucose homeostasis via endocytosis and glucose metabolism plays a vital role in T2DM,the associations between intracellular trafficking and diabetes pathogenesis have not been sufficiently *** this study,we used a Gga3 gene knockout mouse strain to investigate the potential involvement of GGA3 in controlling blood *** study was approved by the ethics committee of Jining Medical University(No.2019-JS-005).Our results indicate that the GGA3 gene might play a protective role against diabetes.

关键词： metabolism elevated protective