检索结果-南通市图书馆

Indication of hydrogen and oxygen stable isotopes on the characteristics and circulation patterns of medium-low temperature geothermal resources in the Guanzhong Basin,China

在线全文

学校读者我要写书评

暂无评论

Journal of Groundwater Science and Engineering 2022年第1期10卷 70-86页

作者： Feng Ma Gui-ling Wang Hong-li Sun zhan-xue Sun The Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuang 050061China Technology Innovation Center for Geothermal&Hot Dry Rock Exploration and Development Minstry of Natural ResourcesShijiazhuang 050061China School of Water Resources&Environmental Engineering East China University of TechnologyNanchang 330000China

Guanzhong Basin is a typical medium-low temperature geothermal field mainly controlled by geo-pressure in the west of *** characteristics of hydrogen and oxygen isotopes were used to analyze the flow and storage modes of geothermal resources in the *** this paper,the basin was divided into six geotectonic units,where a total of 121 samples were collected from geothermal wells and surface water bodies for the analysis of hydrogen-oxygen *** results show that the isotopic signatures of hydrogen and oxygen throughout Guanzhong Basin reveal a trend of gradual increase from the basin edge areas to the basin *** terms of recharge systems,the area in the south edge belongs to the geothermal system of Qinling Mountain piedmont,while to the north of Weihe fault is the geothermal system of North mountain piedmont,where the atmospheric temperature is about 0.2℃-1.8℃in the recharge *** main factors that affect the geothermal waterδ18O drifting include the depth of geothermal reservoir and temperature of geothermal reservoir,lithological characteristics,water-rock interaction,geothermal reservoir environment and residence ***δ18O-δD relation shows that the main source is the meteoric water,together with some sedimentary water,but there are no deep magmatic water and mantle water which recharge the geothermal water in the *** examining the distribution pattern of hydrogen-oxygen isotopic signatures,the groundwater circulation model of this basin can be divided into open circulation type,semi-open type,closed type and sedimentary *** provides some important information for rational exploitation of the geothermal resources.

关键词： Guanzhong Basin Hydrogen-oxygen isotopes Storage characteristics Circulation model

Interval Valued (∈,∈ ∨q)-Fuzzy Filters of MTL-Algebras

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mathematical Research and Exposition 2010年第2期30卷 265-276页

作者： xue Ling MA Jian Ming zhan Kar Ping SHUM Department of Mathematics Hubei Institute for Nationalities Hubei 445000 P. R. China Department of Mathematics The University of Hong Kong Hong Kong P. R. China (SAR)

The concepts of interval valued （∈,∈ ∨q）-fuzzy Boolean, MV - and G- filters in a MTL-algebra are introduced. The properties of these generalized fuzzy filters are studied and in particular, the relationships betw... 详细信息

关键词： MTL-algebra filter interval valued (∈,∈ ∨q)-fuzzy (Boolean, MV- and G-) filters.

Diagnosis and spontaneous healing of asymptomatic renal allograft extra-renal pseudo-aneurysm:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第16期9卷 3943-3950页

作者： Rui-Fang Xu En-Hui He zhan-Xiong Yi Li Li Jun Lin Lin-xue Qian Department of Ultrasound Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Department of Urology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China

BACKGROUND Transplant renal artery stenosis is a relatively frequent vascular complication after ***,extra-renal pseudo-aneurysms(EPSAs)are rare after transplantation;they can be life-threatening and usually need open surgical *** discuss the diagnosis and spontaneous healing of an asymptomatic renal allograft EPSA caused by renal artery anastomotic stenosis,which was diagnosed in a timely manner and managed by conservative *** SUMMARY We present a 37-year-old male patient diagnosed with a renal allograft EPSA caused by renal artery anastomotic stenosis due to multiple atherosclerotic plaques with ultrasonographic examination 6 mo post *** stenosis rate of 90%and the EPSA were verified by computed tomography *** diagnosis was further confirmed with digital subtraction *** transluminal angiography was conducted,and a metallic stent was successfully implanted at the stenosed site of the main renal artery *** further intervention for the EPSA was undertaken due to the difficulty of stenting and the risk of bleeding;regular ultrasonographic follow-ups were *** stenosis was significantly relieved immediately after stent implantation and the EPSA was healed spontaneously by completely filling with hypo-echoic thrombosis 8 mo after *** Ultrasonography combined with a high-frequency linear probe can detect vascular complications post renal transplantation at an early stage and improve prognosis.

关键词： Renal transplantation Renal artery stenosis Pseudo-aneurysm Ultrasonography Vascular complications Case report

Efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in nasopharyngeal carcinoma in vitro and in vivo

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Communications 2018年第1期38卷 179-187页

作者： Yan Huang Ying Tian Yuanyuan Zhao Cong xue Jianhua zhan Lin Liu Xiaobo He Li zhang State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapySun Yat-sen University Cancer CenterGuangzhou 510060GuangdongP.R.China Department of Medical Oncology Sun Yat-sen University Cancer CenterGuangzhou 510060GuangdongP.R.China Department of Experimental Research Sun Yat-Sen University Cancer CenterGuangzhou 510060GuangdongP.R.China Department of Medical Oncology The Fifth Affiliated HospitalSun Yat-Sen UniversityZhuhai 519000GuangdongP.R.China Department of Radiation Oncology The Fifth Affiliated HospitalSun Yat-Sen UniversityZhuhai 519000GuangdongP.R.China

Background:Tumor hypoxia is considered an important factor in metastasis and disease *** is a hypoxia-activated prodrug that selectively targets the hypoxic regions of solid *** hypoxia-inducible factor-1α(HIF-1α)is overexpressed in nasopharyngeal carcinoma(NPC)tissues,we performed the present study to evaluate the efficacy profile of evofosfamide in ***:We evaluated the efficacy of evofosfamide as a single agent or combined with cisplatin(DDP)in the NPC cell lines CNE-2,HONE-1 and HNE-1,and in nude mouse xenograft tumor ***:Evofosfamide exhibited hypoxia-selective cytotoxicity in NPC cell lines,with 50%inhibition concentration(IC50)values of 8.33±0.75,7.62±0.67,and 0.31±0.07μmol/L under hypoxia in CNE-2,HONE-1 and HNE-1 cells,*** sensitization ranged from ninefold to greater than 300-fold under hypoxia compared with normoxia *** combination of evofosfamide with DDP had a synergistic effect on cytotoxicity in the NPC cell lines by combination index values *** cycle G2 phase was arrested after treated with 0.05μmol/L evofosfamide under *** H2AX phosphorylation(γH2AX)(a marker of DNA damage)expression increased while HIF-1αexpression suppressed after evofosfamide treatment under hypoxic *** the HNE-1 NPC xenograft models,evofosfamide exhibited antitumor activity both as a single agent and combined with *** regions in xeno-graft tissue were reduced after both evofosfamide monotherapy and combined therapy with ***:Our results present preclinical evidence for targeting the selective hypoxic portion of NPC by evofosfa-mide as a single agent and combined with DDP and provide rationale for the potential clinical application of evofosfa-mide for the treatment of nasopharyngeal carcinoma.

关键词： Nasopharyngeal carcinoma(NPC) Hypoxia-induced factor-1α(HIF-1α) Hypoxia-activated prodrug Chemotherapy Xenograft tumor models

煤岩变形破坏电磁辐射记忆效应的力电耦合规律

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

地球物理学报 2006年第5期49卷 1517-1522页

作者：撒占友何学秋王恩元青岛理工大学安全工程系青岛266520 中国矿业大学能源与安全工程学院徐州221008

理论分析了煤岩变形破坏过程中电磁辐射脉冲数与损伤之间的关系,探讨了煤岩变形破坏电磁辐射产生机制及电磁辐射记忆效应的力电耦合规律,建立了等围压三轴应力状态下含瓦斯煤岩变形破坏电磁辐射记忆效应的力电耦合模型,实验测定并分析... 详细信息

理论分析了煤岩变形破坏过程中电磁辐射脉冲数与损伤之间的关系,探讨了煤岩变形破坏电磁辐射产生机制及电磁辐射记忆效应的力电耦合规律,建立了等围压三轴应力状态下含瓦斯煤岩变形破坏电磁辐射记忆效应的力电耦合模型,实验测定并分析了单轴压缩状况下含瓦斯煤岩变形破坏电磁辐射记忆效应的力电耦合规律.结果表明,含瓦斯煤岩变形破坏电磁辐射记忆效应力电耦合模型很好地反映了煤岩变形破坏电磁辐射记忆效应特征规律和微观损伤机理.

关键词：煤岩电磁辐射记忆效应力电耦合

Burst Phase Distribution of SGR J1935+2154 Based on Insight-HXMT

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2023年第3期23卷 68-74页

作者： xue-Feng Lu Li-Ming Song Ming-Yu Ge you-Li Tuo Shuang-Nan zhang Jin-Lu Qu Ce Cai Sheng-Lun Xie Cong-zhan Liu Cheng-Kui Li Yu-Cong Fu Ying-Chen Xu Tian-Ming Li Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China College of Physics and Hebei Key Laboratory of Photophysics Research and Application Hebei Normal UniversityShijiazhuang 050024China Institute of Astrophysics Central China Normal UniversityWuhan 430079China

On 2020 April 27,the soft gamma-ray repeater SGR J1935+2154 entered its intense outburst episode ***-HXMT carried out about one month observation of the source.A total number of 75 bursts were detected during this activity episode by Insight-HXMT,and persistent emission data were also *** report on the spin period search result and the phase distribution of burst start times and burst photon arrival times of the Insight-HXMT high energy detectors and Fermi/Gamma-ray Burst Monitor(GBM).We find that the distribution of burst start times is uniform within its spin phase for both Insight-HXMT and Fermi/GBM observations,whereas the phase distribution of burst photons is related to the type of a burst’s energy *** bursts with the same spectrum have different distribution characteristics in the initial and decay episodes for the activity of magnetar SGR J1935+2154.

关键词： spectrum Fermi distribution

Tumor-derived miR-20b-5p promotes lymphatic metastasis of esophageal squamous cell carcinoma by remodeling the tumor microenvironment

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2023年第2期8卷 369-372页

作者： Zitong Zhao Liyan xue Leilei Zheng Liying Ma Zhuo Li Ning Lu Qimin zhan Yongmei Song State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Pathology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Laboratory of Molecular Oncology Peking University Cancer HospitalBeijingChina

DEAREDITOR,Esophageal squamous cell carcinoma(ESCC)is one of the most common fatal malignancies worldwide and is especially common in East Asian regions,including *** lymph node metastasis(LNM)-related biomarkers and elucidating the mechanism could provide promising therapeutic targets and help ESCC patients to select reasonable individual therapies.

关键词： metastasis squamous esophageal

Darboux Transformation and Soliton Solutions for Inhomogeneous Coupled Nonlinear Schr(o|¨)dinger Equations with Symbolic Computation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2009年第11期52卷 888-896页

作者： xue Yu-Shan TIAN Bo zhanG Hai-Qiang LIU Wen-Jun LI Li-Li QI Feng-Hua zhan Yan School of Science Beijing University of Posts and Telecommunications P.O. Box 122 Beijing 100876 China State Key Laboratory of Software Development Environment Beijing University of Aeronautics and Astronautics Beijing 100191 China Key Laboratory of Information Photonics and Optical Communications （BUPT） Ministry of Education P.O. Box 128 Beijing University of Posts and Telecommunications Beijing 100876 China

With the aid of computation, we consider the variable-coefficient coupled nonlinear Schrodinger equations with the effects of group-velocity dispersion, self-phase modulation and cross-phase modulation, which have potential applications in the long-distance communication of two-pulse propagation in inhomogeneous optical fibers. Based on the obtained nonisospectral linear eigenvalue problems （i.e. Lax pair）, we construct the Darboux transformation for such a model to derive the optical soliton solutions. In addition, through the one- and two-soliton-like solutions, we graphically discuss the features of picosecond solitons in inhomogeneous optical fibers.

关键词： variable-coefficient coupled nonlinear Schrodinger equations optical solitons Darboux transformation symbolic computation

Robust neutralizing antibody response to the XBB.1.5 trivalent recombinant protein vaccine booster

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第9期9卷 3560-3562页

作者： Bing-Dong zhan xue-Dong Song Xin Yu Guo-Jian Yang Sheng Wan Mai-Juan Ma Quzhou Center for Disease Control and Prevention QuzhouChina State Key Laboratory of Pathogen and Biosecurity Academy of Military Medical SciencesBeijingChina Qujiang District Center for Disease Control and Prevention QuzhouChina Department of Microbiological Laboratory Technology School of Public HealthCheeloo College of MedicineShandong UniversityJinanChina

Dear Editor,The global prevalence of XBB subvariants,known for their significant immune evasion,has driven the development and adaptation of XBB *** XBB.1.5 mRNA vaccines have been developed and shown to provoke robust immune responses against XBB.1.5,EG.5.1,and BA.2.86 following vaccination.1 In June 2023,the XBB.1.5-recombinant COVID-19 trivalent(XBB.1.5+BA.5+Delta)protein vaccine(trivalent XBB.1.5 vaccine)(WestVac Biopharma Co.,Ltd.,China)was approved for emergency use against XBB *** preliminary data from the manufacturer suggest neutralization of several earlier Omicron subvariants and XBB.1.5,there is limited real-world evidence,and persisting immune imprinting may affect the induction of antibodies against new SARS-CoV-2 sublineages,2 such as JN.1,which has increased transmissibility and the ability to evade immunity.3 Additionally,subsequent XBB infection after BA.5/BF.7 breakthrough infection does not efficiently induce humoral immunity against JN.1,4 raising questions about the ability of the trivalent XBB.1.5 vaccine to provide adequate protection against this *** measured the neutralizing antibody responses in 32 individuals who experienced a BA.5/BF.7 breakthrough infection and a subsequent XBB infection before and after receiving the trivalent XBB.1.5 *** detailed demographic information of the study participants and their vaccination and infection histories are described in the Supplementary Methods.

关键词： valent neutral breakthrough