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Asian Pacific Journal of Tropical Medicine 2012年第8期5卷 661-664页

作者： Shi-Jin zhang zhan-you xue Department of Traditional Chinese Medicine People's Hospital of Zhengzhou Department of Neurology the First Affiliated Hospital of Zhengzhou University

Objective:To discuss the clinical effects of Western medicine therapy assisted by Ginkgo biloba tablet(GBT) on patients with vascular cognitive impairment of none dementia(VCIND).Methods: A total of 80 patients with VCIND were divided into two groups randomly:Conventional treatment group(control group) and combined treatment *** treatment group was given conventional treatment with anti-platelet *** this group,75 mg aspirin was given three times a day for 3 *** in combined treatment group,19.2 mg CRT was given three times a day for 3 months together with conventional treatment(anti-platelet aggregation drugs). Montreal cognitive assessment(MoCA) and transcranial Doppler(TCD) were used to observe changes of cognitive ability and cerebral blood flow in VCIND patients before and after treatment in both *** the clinical data were analyzed so as to compare the efficacy in two groups. Results:After 3 month-treatment in combined treatment group,the scores of executive ability, attention,abstract,delayed memory,orientation in the MoCA were significantly increased compared with those before treatment and those in control group after ***,blood flow velocity of anterior cerebral artery increased significandy than that before treatment and that in control group after ***:CBT tablet can improve the therapeutic efficacy as well improve cognitive ability and cerebral blood flow supply of patients with VCIND.

关键词： Combination of traditional Chinese and Western medicine Cognitive impairment Ginkgo tablet Clinical evaluation

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木霉拮抗菌的筛选与鉴定

中国食用菌 2011年第2期30卷 55-57,60页

作者：陈发川詹友学吴小平福建农林大学生命科学学院福建福州350002 福建农林大学菌物研究中心福建福州350002

采用涂布平板法从植物和土壤中共分离得到301株细菌,其中从羊蹄甲、芦荟和香蕉皮等植物中分离到内生细菌86株,从土壤中分离到细菌215株。以食用菌栽培中的主要污染菌木霉,包括哈茨木霉(Trichoderma harzianum)、长枝木霉(Trichoderma lo... 详细信息

采用涂布平板法从植物和土壤中共分离得到301株细菌,其中从羊蹄甲、芦荟和香蕉皮等植物中分离到内生细菌86株,从土壤中分离到细菌215株。以食用菌栽培中的主要污染菌木霉,包括哈茨木霉(Trichoderma harzianum)、长枝木霉(Trichoderma longibrachiatum)等4种共8株木霉菌株以及蘑菇(Agaricus bisporus)、香菇(Lentinula edodes)等14种不同食用菌为实验菌,通过平板对峙培养法筛选出对木霉有拮抗作用而对食用菌拮抗性弱甚至无拮抗作用的细菌75株。采用传统分类法以及16S rDNA序列分析对其中作用效果最好的5株细菌进行了鉴定,结果显示,5株细菌均为枯草芽孢杆菌Bacillus subtilis。在实验中还发现,从羊蹄甲、芦荟和香蕉皮等植物中更容易分离到木霉拮抗菌。

关键词：木霉拮抗细菌食用菌植物内生细菌

食用菌栽培中相关木霉的遗传多样性及生物学特性

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福建农林大学学报（自然科学版） 2008年第5期37卷 527-531页

作者：吴小平吴晓金胡方平詹友学福建农林大学生命科学学院福建农林大学植物保护学院福建福州350002

对不同地理来源的49株木霉菌株用5个RAPD引物扩增.结果表明,木霉种间和种内具有丰富的遗传多样性,菌株间差异与地理来源和寄主有一定相关.系统发育树反映的种间关系与形态分类结果基本一致,不同地理来源的相同种可以通过RAPD分析区分开... 详细信息

对不同地理来源的49株木霉菌株用5个RAPD引物扩增.结果表明,木霉种间和种内具有丰富的遗传多样性,菌株间差异与地理来源和寄主有一定相关.系统发育树反映的种间关系与形态分类结果基本一致,不同地理来源的相同种可以通过RAPD分析区分开来.木霉的生物学特性研究结果表明:木霉生长的最适温度、最适含水量和最适pH分别为28℃、70%和5.7;木霉对35℃以上的高温适应性差异较大,在高温干燥环境下易产孢子,在潮湿环境下孢子最易萌发,菌丝生长旺盛,在pH为11的培养基中不能生长.

关键词：木霉食用菌遗传多样性生物学特性 RAPD

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木霉对食用菌侵染能力的分析

福建农业学报 2007年第4期22卷 354-359页

作者：吴晓金詹友学吴小平福建农林大学生命科学学院

研究了49株木霉对食用菌菌丝的侵染能力,结果显示:不同木霉的侵染能力不同,对食用菌侵染能力强的木霉对植物病原真菌的侵染能力并不一定强,表现出木霉对真菌侵染的特异性。木霉侵染食用菌的机理研究结果显示:木霉可通过溶壁、缠绕等方... 详细信息

研究了49株木霉对食用菌菌丝的侵染能力,结果显示:不同木霉的侵染能力不同,对食用菌侵染能力强的木霉对植物病原真菌的侵染能力并不一定强,表现出木霉对真菌侵染的特异性。木霉侵染食用菌的机理研究结果显示:木霉可通过溶壁、缠绕等方式作用于食用菌菌丝细胞壁,木霉发酵液对食用菌和植物病原菌都有很好的抑制作用,但木霉产几丁质酶的能力与木霉的侵染能力没有直接关系。

关键词：木霉食用菌侵染机理生物防治

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氨基酸共聚物修饰的生物相容性MRI造影剂

波谱学杂志 2016年第4期33卷 635-645页

作者：湛游洋薛蓉祝云龙李晓晶裴奉奎冯江华中国科学院长春应用化学研究所吉林长春130022 中国科学院大学北京100049 厦门大学电子科学系福建厦门361005

通过天门冬氨酸(Asp)、异亮氨酸(Ile)热缩聚反应,制备了天门冬氨酸-异亮氨酸共聚物(AI),通过乙二胺(EDA)胺化,并与1,4,7,10-四氮杂环十二烷-1,4,7,10-四羧酸(DOTA)连接,再与钆离子(Gd3+)络合,合成了生物相容性大分子磁共振成像(MRI)造... 详细信息

通过天门冬氨酸(Asp)、异亮氨酸(Ile)热缩聚反应,制备了天门冬氨酸-异亮氨酸共聚物(AI),通过乙二胺(EDA)胺化,并与1,4,7,10-四氮杂环十二烷-1,4,7,10-四羧酸(DOTA)连接,再与钆离子(Gd3+)络合,合成了生物相容性大分子磁共振成像(MRI)造影剂——AI-EDA-DOTA-Gd.运用红外光谱(IR)、核磁共振(NMR)、电感耦合等离子谱(ICP)等方法对其进行结构表征,并通过弛豫性能、溶血性质、急性毒性及动物体内成像对其进行综合评价.体外弛豫结果表明,AI-EDA-DOTA-Gd的纵向弛豫效率(r_1=12.6mmol^(–1)×L×s^(–1))是商用造影剂Gd-DOTA(r_1=5.8 mmol^(–1)×L×s^(–1))的2.2倍.动物组织生理切片和溶血性实验结果说明其具有良好的生物相容性和较低的毒性.动物体内成像结果显示,AI-EDA-DOTA-Gd的最佳成像时间为30~70 min,注射AI-EDA-DOTA-Gd后的肝脏组织信号相比于未注射造影剂时增强了约(55.1±5.7)%.

关键词： MRI造影剂弛豫效率氨基酸共聚物大分子配合物生物相容性

Mechanical properties of Mn-doped ZnO nanowires studied by first-principles calculations

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International Journal of Minerals,Metallurgy and Materials 2012年第1期19卷 89-94页

作者： zhan-jun Gao you-song Gu xue-qiang Wang Yue zhang School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China

First-principles calculations were performed to investigate the mechanical properties of ZnO nanowires and to study the doping and size effects. A series of strains were applied to ZnO nanowires in the axial direction and the elastic moduli of ZnO nanowires were obtained from the energy versus strain curves. Pure and Mn-doped ZnO nanowires with three different diameters （1.14, 1.43, and 1.74 nm） were studied. It is found that the elastic moduli of the ZnO nanowires are 146.5, 146.6, and 143.9 GPa, respectively, which are slightly larger than that of the bulk （140.1 GPa）, and they increase as the diameter decreases. The elastic moduli of the Mn-doped ZnO nanowires are 137.6, 141.8, and 141.0 GPa, which are slightly lower than those of the undoped ones by 6.1%, 3.3%, and 2.0%, respectively. The mechanisms of doping and size effect were discussed in terms of chemical bonding and geometry considerations.

关键词： zinc oxide nanowires mechanical properties doping first-principles calculations manganese

The Feasibility Research on Reusing High Salinity Wastewater as a Plant Nutrient Medium for Plant Hydroponics in CELSS

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Space(Science & Technology) 2022年第1期2022卷 370-380页

作者： Liangchang zhang Yurong xue you Wang Chengbo zhan Weidang Ai Xingyan Wang National Key Laboratory of Human Factors Engineering China Astronaut Research and Training CenterBeijing 100094China Department of Environmental Science and Engineering College of Environment and ResourcesXiangtan UniversityXiangtan 411105China Space Institute of Southern China Shenzhen 518117China

The reuse of wastewater is a key problem in controlled ecological life support system(CELSS).In this study,the feasibility to reuse the treated wastewater(including sanitary wastewater and urine wastewater)as a plant hydroponic medium was *** salt-tolerant plants,apium graveolens Linn(celery)and mesembryanthemum cordifolium L.F.(cordifolium),were cultivated with the reused medium or Hoagland nutrient solution,and the characteristics of crop growth,hydroponic medium composition,and elements absorption by plants were *** results showed that the reused medium replenished with micronutrient elements could maintain the normal growth of cordifolium and celery *** biomass productivity of cordifolium cultivated by the recycled medium(121.53 g FW/strain)was higher than that cultivated by Hoagland nutrient solution(98.33 g FW/strain).The nutrient elements accumulation in plant dry mass indicated that plants could effectively utilize the recycled mineral elements in wastewater,and cordifolium exhibited better stability and adaptability to salt-induced *** absorption capacity of Na and Cl elements in cordifolium cultivated within the reused medium was the highest,which was 4.54%DW and 2.63%DW,*** study demonstrated the feasibility to directly reuse domestic wastewater as the main ingredient for plant hydroponics,which could provide insights into design and operation of plant hydroponics system and water circulation system in CELSS.

关键词： wastewater Plant utilize

Influence of the Choice of Core-Envelope Transition Point on the Binary Merger of Two Main-sequence Components

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Chinese Journal of Astronomy and Astrophysics 2005年第1期5卷 65-76页

作者： xue-FeiChen zhan-WenHan NationalAstronomicalObservatories YunnanObservatoryChineseAcademyofSciencesKunming650011／／GraduateSchooloftheChineseAcademyofSciencesBeijing100039 NationalAstronomicalObservatories YunnanObservatoryChineseAcademyofSciencesKunming650011

We have studied the influence of different choices of core-envelope transition point on the final merger of contact binaries with two main-sequence components. A binary of 1.00 + 0.90M⊙ with an initial orbital period of 0.35d is examined. The mass fraction of the primary mixed with the matter of the secondary, qmix, determined by the chosen core-envelope transition point, ranges from 0.04 to 1.00 in our analysis. If as qmix 0.71, the larger qmix is, the greater the mixing, hence the longer the blue straggler lifetime, tBS, and also the greater the luminosity. For qmix= 1.00, tBS -8.5×108yr. Estimation by (?)r - (?)a = 0.0 shows that the point at which tBS begins to increase is about qmix= 0.68. In comparison with the homogeneously mixed models, the merger with a helium profile similar to that of the primary is less luminous and has a shorter tBS.

关键词： stars: binaries - stars: evolution - stars: blue stragglers

CRISPR/Cas9-based functional analysis of yellow gene in the diamondback moth,Plutella xylostella

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Insect Science 2021年第5期28卷 1504-1508,I0002页

作者： Yajun Wang Yuping Huang xuejiao Xu Zhaoxia Liu Jianyu Li xue zhan Guang Yang Minsheng you Shijun you State Key Laboratory of Ecological Pest Control for Fujian-Taiwan Crops Institute of Applied EcologyFujian Agriculture and Forestry UniversityFuzhou 350002China Joint International Research Laboratory of Ecological Pest Control Ministry of EducationFuzhou 350002China Key Laboratory of Integrated Pest Management for Fujian-Taiwan Crops Ministry of AgricultureFuzhou 350002China ADepartment of Physiology&Neurobiology University of ConnecticutStorrsCT 06269USA Fujian Key Laboratory for Monitoring and Integrated Management of Crop Pests Institute of Plant ProtectionFujian Academy of Agricultural SciencesFuzhou 350013China

The diamondback moth,Plutella xylostella(L.),is an economically important pest of cruciferous crops *** pest is notorious for rapid evolution of the resistance to diferent classes of insecticides,making it increasingly dificult to ***-based control approaches,through manipulation of target genes,have been reported as promising supplements or alternatives to traditional methods of pest *** we identified a gene of pigmentation(yellow)in ***,Pxyellow,which encodes 1674 bp complementary DNA sequence with four exons and three *** the clustered regularly interspersed palindromic repeats(CRISPR)CRISPR-associated protein 9 system,we knocked out Pxyellow,targeting two sites in Exon III,to generate 272 chimeric mutants(57%of the CRISPR-treated individuals)with color-changed phenotypes of the Ist to 3rd instar larvae,pupae,and adults,indicating that Pxyellow plays an essential role in the body pigmentation of P *** analysis revealed no significant difference in the oviposition of adults,the hatchability of eggs,and the weight of pupac between homozygous mutants and wildtypes,suggesting that Pxyellow is not directly involved in regulation of growth,development,or *** work advances our understanding of the genetic and insect science molecular basis for body pigmentation of P xylostella,and opens a wide avenue for development of the genctcally based pest control techniques using Pxyellow as a screening marker.

关键词： CRISPR/Cas9 diamondback moth genetically based control novel marker yellow gene

Wave Attenuation Performance and the Influencing Factors of A Lower Arc-Plate Breakwater

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China Ocean Engineering 2020年第1期34卷 89-98页

作者： LI xue-yan WANG Qing you Zai-jin GUO Wei-jun zhanG Jun-bin zhan Chao zhanG Zhi-chen WANG Li-xue LI Qin Coast Institute Ludong UniversityYantai 264025China Dalian Maritime University Dalian 116026China Institute of Sea-Crossing Engineering Ludong UniversityYantai 264024China College of Environmental Sciences and Engineering Dalian Maritime UniversityDalian 116026China

Comprehensive experimental and numerical studies have been undertaken to investigate wave energy dissipation performance and main influencing factors of a lower arc-plate breakwater. The numerical model, which considers nonlinear interactions between waves and the arc-plate breakwater, has been constructed by using the velocity wave- generating method, the volume of fluid (VOF) method and the finite volume method. The results show that the relative width, relative height and relative submergence of the breakwater are three main influencing factors and have significant influence on wave energy dissipation of the lower arc-plate open breakwater. The transmission coefficient is found to decrease with the increasing relative width, and the minimum transmission coefficient is 0.15 when the relative width is 0.45. The reflection coefficient is found to vary slightly with the relative width, and the maximum reflection coefficient is 0.53 when the relative width is 0.45. The transmission and reflection coefficients are shown to increase with the relative wave height for approximately 85% of the experimental tests when the relative width is 0.19 0.45. The transmission coefficients at relative submergences of 0.04, 0.02 and 0 are clearly shown to be greater than those at relative submergences of 0.02 and 0.04, while the reflection coefficient exhibits the opposite relationship. After the wave interacts with the lower arc-plate breakwater, the wave energy is mainly converted into transmission, reflection and dissipation energies. The wave attenuation performance is clearly weakened for waves with greater heights and longer periods.

关键词： arc-plate breakwater wave attenuation performance influencing factors VOF method