检索结果-南通市图书馆

Preparation of water-soluble tantalum nanoparticles and their radiosensitization application

在线全文

学校读者我要写书评

暂无评论

Tungsten 2024年第4期6卷 748-758页

作者： Wang zhang Shuang-Long Du Zhi-guo zhang Tao Wang Chun-Jian Su Xing-Hua Dong Shuang Zhu zhan-jun gu College of Mechanical and Electronic Engineering Shandong University of Science and Technology CAS Key Laboratory for Biomedical Eff ects of Nanomaterials and Nanosafety Institute of High Energy Physics Chinese Academy of Science GBA Research Innovation Institute for Nanotechnology CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology of China Chinese Academy of Sciences

Radiation therapy(RT) that utilizes high dose of ionizing radiation to kill tumor cells is a common cancer treatment ***,the effectiveness of RT is limited by the tolerance of normal tissue surrounding the *** high atom number(Z) element-based radio sensitizers to increase energy deposit inside tumor cells can achieve better carcinoma *** nanoparticles(Ta NPs) exhibit good radiotherapy sensitization ***,achieving the water solubility of Ta NPs is *** study reported a mechanochemical method for obtaining Ta NPs modified with sodium hexametaphosphate(SHMP) for radiotherapy sensitization *** results showed that the water solubility of Ta NPs modified with SHMP was significantly *** biocompatibility and radio sensitizing ability are also verified at both cellular and animal levels.

关键词： Mechanochemical method Radiotherapy sensitization Sodium hexametaphosphate Tantalum nanoparticles

Volume of fluid simulation of single argon bubble dynamics in liquid steel under RH vacuum conditions

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第4期31卷 828-837页

作者： gu-jun Chen Sheng-ping He College of Materials Science and Engineering Yangtze Normal UniversityChongqing 400044China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China

Single argon bubble dynamics in liquid steel under Ruhrstahl-Heraeus(RH)vacuum conditions were simulated using the volume of fluid method,and the ideal gas law was used to consider bubble growth due to heat transfer and pressure *** simulation with a constant bubble density was also performed to validate the numerical method,and the predicted terminal bubble shape and velocity were found to agree with those presented in the Grace diagram and calculated by drag correlation,*** simulation results under RH conditions indicate that the terminal bubble shape and velocity cannot be *** primary bubble growth occurs within a rising distance of 0.3 m owing to heating by the high-temperature liquid steel;subsequently,the bubble continues to grow under equilibrium with the hydrostatic *** the initial diameter is 8-32 mm,the bubble diameter and rising velocity near the liquid surface are 80-200 mm and 0.5-0.8 m/s,*** bubble rises rectilinearly with an axisymmetric shape,and the shape evolution history includes an initial sphere,(dimpled)ellipsoid,and spherical cap with satellite bubbles.

关键词： Bubble dynamics Liquid steel Volume of fluid Bubble growth Bubble shape Rising velocity

Prediction of liquid circulation flow rate in RH degasser:improvement of decarburization at low atmospheric pressure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第7期31卷 1661-1667页

The two-fluid model coupled with population balance model was used for simulating the gas-liquid flow in the Ruhrstahl-Heraeus(RH)*** predicted circulation flow rate was compared with that measured from a water model experiment to validate the mathematical ***,influence of snorkel immersion depth on liquid circulation flow rate was numerically investigated under an atmospheric pressure of 101 and 84 kPa,*** result indicates that the circulation flow rate of the RH degasser in the high-altitude area was severely reduced because of the decrease in atmospheric ***,increasing the snorkel immersion depth from 0.5 to 0.7 m can compensate for the decrease in atmospheric *** test result indicates that decarburization rate is significantly enhanced by increasing the snorkel immersion *** optimization,the percentage of heats with a final carbon content less than 0.002 wt.%is significantly increased from 22.0%to 96.4%.

关键词： RH degasser Two-fluid model Population balance model-Circulation flow rate Decarburization Snorkel immersion depth

Impact of atmospheric circulations on droughts and drought propagation over China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2024年第8期67卷 2633-2648页

作者： Ziye gu Lei gu Jiabo YIN Wei FANG Lihua XIONG jun guO Ziyue ZENG jun XIA School of Civil and Hydraulic Engineering Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Water Resources Engineering and Management Wuhan 430072China Changjiang River Scientific Research Institute Wuhan 430010China

The GRACE satellite mission provides a new approach for monitoring,tracking,and assessing drought conditions by detecting changes in Earth's gravitational fields and inversing signals of terrestrial water storage *** studies of terrestrial water storage anomalies related droughts paid rare attention to the behind atmospheric physical mechanisms,nor quantified the risk propagation patterns between terrestrial water storage deficits and hydrological or agricultural *** this study,we first extract terrestrial water storage(TWS) droughts,hydrological droughts,and agricultural droughts by using multiple variables including TWS from the GRACE/GRACE-FO satellites,runoff and soil moisture from the ERA5-Land reanalysis *** then identify key atmospheric and oceanic oscillation indices affecting water deficits by employing machine learning *** characterize the joint distributions between drought duration and severity by using the Copula function and quantify the risk propagation of hydrological and agricultural droughts to TWS *** results show that:(1) From 2002 to 2021,there is a significant decrasing trend of TWS in China;the WPIO group atmospheric circulation indices(sea surface temperature index within the Western Pacific and Indian Ocean) contributes the most to ***,the sea surface temperature anomalies within the NINO 3.4 region as well as the Western Pacific Warm Pool area index show significantly positive correlation relationships with TWS in southern China;(2) The northwestern China,the Yangtze River basin,and the downstream of the Pearl River basin are the hotspots of TWS ***,the hotspots of hydrological droughts locate in northwestern China and the hotspots of agricultural droughts locate in South China and eastern Tibetan Plateau;(3) The elastic coefficients of hydrological droughts propagating to TWS droughts are higher than those of agricultural droughts,indicating that the TWS droughts

关键词： GRACE satellites Drought Drought propagation Atmospheric circulation Copula function

同方期刊数据库

The essential roles of m^(6)A modification in osteogenesis and common bone diseases

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第1期11卷 335-345页

作者： Yuxi gu Yidan Song Yihua Pan jun Liu State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases Department of OrthodonticsWest China Hospital of StomatologySichuan UniversityChengduSichuan 610041China

N6-methyladenosine(m^(6)A)is the most prevalent modification in the eukaryotic transcriptome and has a wide range of functions in coding and noncoding *** affects the fate of the modified RNA,including its stability,splicing,and translation,and plays an important role in post-transcriptional *** play a key role in supporting and pro-tecting muscles and other organs,facilitating the movement of the organism,ensuring blood production,*** diseases such as osteoarthritis,osteoporosis,and bone tumors are serious public health *** processes of bone development and osteogenic differen-tiation require the precise regulation of gene expression through epigenetic mechanisms including histone,DNA,and RNA *** a reversible dynamic epigenetic mark,m^(6)A modifications affect nearly every important biological process,cellular component,and molecular function,including skeletal development and *** recent years,studies have shown that m^(6)A modification is involved in osteogenesis and bone-related *** this review,we summarized the proteins involved in RNA m^(6)A modification and the latest progress in elucidating the regulatory role of m^(6)A modification in bone formation and stem cell direc-tional *** also discussed the pathological roles and potential molecular mech-anisms of m^(6)A modification in bone-related diseases like osteoporosis and osteosarcoma and suggested potential areas for new strategies that could be used to prevent or treat bone de-fects and bone diseases.

关键词： Bone diseases m^(6)A modification Osteogenesis Regulatory role Stem cells

Compressed Data Separation via ℓ_(q)-Split Analysis with ℓ_(∞)-Constraint

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年第7期40卷 1655-1673页

作者： Ming Yang gu Song Li jun Hong Lin School of Mathematical Science Zhejiang UniversityHangzhou310027P.R.China Center for Data Science Zhejiang UniversityHangzhou310027P.R.China

In this paper,we study compressed data separation(CDS)problem,i.e.,sparse data separation from a few linear random *** propose the nonconvex ℓ_(q)-split analysis with ℓ_(∞)-constraint and 0 详细信息

In this paper,we study compressed data separation(CDS)problem,i.e.,sparse data separation from a few linear random *** propose the nonconvex ℓ_(q)-split analysis with ℓ_(∞)-constraint and 0

关键词： Data separation ℓ_(q)-split analysis Dantzig selector frames restricted isometry property compressed sensing

Special Issue: Functional Polymer Materials

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第7期42卷 895-896,I0004页

作者： gu, jun-Wei Wang, Du-Jin Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical Engineering Northwestern Polytechnical University Xi’an China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Engineering Plastics Institute of Chemistry Chinese Academy of Sciences Beijing China

The rapid development of science has led to a significant role for polymer materials in multitude fields,including industry,medicine,energy,and the environment,*** a leading academic journal in the field of polymer,Chinese Journal of Polymer Science has been dedicated to fostering the advancement and utilization of polymer science.

关键词： polymer Polymer Functional

Suppressing dendritic metallic Li formation on graphite anode under battery fast charging

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第4期91卷 484-500页

作者： Shiyu Liu Baoqi gu Zihe Chen Renming zhan Xiancheng Wang Ruikang Feng Yongming Sun Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074HubeiChina

Lithium-ion batteries(LIBs)with fast-charging capability are essential for enhancing consumer experience and accelerating the global market adoption of electric ***,achieving fast-charging capability without compromising energy density,cycling lifespan,and safety of LIBs remains a significant challenge due to the formation of dendritic Li metal on graphite anode under fast charging *** view of this,the fundamentals for the dendritic metallic Li formation and the strategies for suppressing metallic Li plating based on analyzing the entire Li^(+)transport pathway at the anode including electrolyte,pore structure of electrode,and surface and bulk of materials are summarized and discussed in this ***,we highlight the importance of designing thick electrodes with fast Li^(+)transport kinetics and comprehensively understanding the interaction between solid electrolyte interphase(SEI)and Li^(+)migration in order to avoid the formation of dendritic Li metal in practical fast-charging ***,the regulation of Li metal plating with plane morphology,instead of dendritic structure,on the surface of graphite electrode under fast-charging condition is analyzed as a future direction to achieve higher energy density of batteries without safety concerns.

关键词： Safety Fast-charging lithium-ion batteries Dendritic metallic lithium Li^(+) transport

Modulated Degradation Rates of Bone Mineral-Like Calcium Phosphate Glass to Support the Proliferation and Osteogenic Differentiation of Bone Marrow-Derived Stem Cells

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2024年第4期21卷 1960-1974页

作者： Lizhe He Yuye Huang Jiafei gu Xiaoling Liu jun Yin Xiang Gao Department of Neurosurgery The First Affiliated Hospital of Ningbo UniversityNingbo315010China Center for Medical and Engineering Innovation The First Affiliated Hospital of Ningbo UniversityNingbo315010China The State Key Laboratory of Fluid Power Transmission and Control Systems Key Laboratory of 3D Printing Process and Equipment of Zhejiang ProvinceSchool of Mechanical EngineeringZhejiang UniversityHangzhou310028China Faculty of Science and Engineering University of Nottingham Ningbo ChinaNingbo315100China

With an elemental composition similar to bone mineral,and the ability to release phosphorus and calcium that benefit bone regeneration,Calcium Phosphate Glass(CPG)serves as a promising component of bone tissue engineering ***,the degradation of CPG composites typically results in increased acidity,and its impact on bone-forming activity is less *** this work,we prepared 3D-printed composite scaffolds comprising CPG,Poly-ε-caprolactone(PCL),and various Magnesium Oxide(MgO)*** the MgO content effectively suppressed the degradation of CPG,maintaining a physiological pH of the degradation *** the degradation of CPG/PCL scaffolds resulted in upregulated apoptosis of Rat Bone Marrow-derived Stem Cells(rBMSC),scaffolds containing MgO were free from these negative impacts,and an optimal MgO content of 1 wt%led to the most pronounced osteogenic differentiation of *** work demonstrated that the rapid degradation of CPG impaired the renewability of stem cells through the increased acidity of the surrounding media,and MgO effectively modulated the degradation rate of CPG,thus preventing the negative effects of rapid degradation and supporting the proliferation and osteogenic differentiation of the stem cells.

关键词： Phosphate glass Polymer composites 3D printing Bone tissue engineering Scaffolds