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Prediction and analysis of albumin-bilirubin score combined with liver function index and carcinoembryonic antigen on liver metastasis of colorectal cancer

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1670-1680页

作者： zhan-mei Wang Shu-Ping Pan Jing-Jing zhang Jun Zhou Department of Medical Oncology Qilu Hospital(Qingdao)Cheeloo College MedicineShandong UniversityQingdao 266000Shandong ProvinceChina Department of Gastroenterology Feicheng People’s HospitalFeicheng 271600Shandong ProvinceChina Department of Anus and Intestine Surgery Xiangya Hospital of Central South UniversityChangsha 410008Hunan ProvinceChina Department of Oncology Qilu Hospital(Qingdao)Cheeloo College MedicineShandong UniversityQingdao 266000Shandong ProvinceChina

BACKGROUND Colorectal cancer(CRC)is a common malignant tumor,and liver metastasis is one of the main recurrence and metastasis modes that seriously affect patients’survival rate and quality of *** such as albumin bilirubin(ALBI)score,liver function index,and carcinoembryonic antigen(CEA)have shown some potential in the prediction of liver metastasis but have not been fully *** To evaluate its predictive value for liver metastasis of CRC by conducting the combined analysis of ALBI,liver function index,and CEA,and to provide a more accurate liver metastasis risk assessment tool for clinical treatment *** This study retrospectively analyzed the clinical data of patients with CRC who received surgical treatment in our hospital from January 2018 to July 2023 and were followed up for 24 *** to the follow-up results,the enrolled patients were divided into a liver metastasis group and a nonliver metastasis group and randomly divided into a modeling group and a verification group at a ratio of 2:*** risk factors for liver metastasis in patients with CRC were analyzed,a prediction model was constructed by least absolute shrinkage and selection operator(LASSO)logistic regression,internal validation was performed by the bootstrap method,the reliability of the prediction model was evaluated by subject-work characteristic curves,calibration curves,and clinical decision curves,and a column graph was drawn to show the prediction *** Of 130 patients were enrolled in the modeling group and 65 patients were enrolled in the verification group out of the 195 patients with CRC who fulfilled the inclusion and exclusion *** LASSO regression variable screening and logistic regression *** ALBI score,alanine aminotransferase(ALT),and CEA were found to be independent predictors of liver metastases in CRC patients[odds ratio(OR)=8.062,95%confidence interval(CI):2.545-25.540],(OR=1.037,95%CI:1.004-1.071)and(OR=1.0

关键词： Albumin-bilirubin Carcinoembryonic antigen Colorectal cancer Tumor metastasis Prediction model

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Design,preparation,microstructure and mechanical property of the lightweight radiation-shielding Mg-Ta-Al composites basing differential temperature hot rolling

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Journal of Magnesium and Alloys 2024年第6期12卷 2433-2446页

作者： Wenbo Luo Songya Feng Xiuzhu Han Li Zhou Qinke Kong Zhiyong Xue Jianzhao Wang mei zhan Xianhua Chen Fusheng Pan Institute for Advanced Materials North China Electric Power UniversityBeijing 102206China Beijing Institute of Spacecraft System Engineering Beijing 100094China Sinosteel Equipment&Engineering Co Ltd.Beijing100080China State Key Laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive Utilization Inner Mongolia 014030China School of Materials Science Northwestern Polytechnical UniversityXi’an 710072China College of Materials Science and Engineering Chongqing UniversityChongqing 400045China

A novel lightweight,radiation-shielding Mg-Ta-Al layered metal-matrix composite(LMC)was successful designed by doping the extremely refractory metal(Ta)into Mg *** Mg-based LMCs sheets shows excellent radiation-dose shield effect,about 145 krad·a^(−1),which is about 17 times of traditional Mg alloy,while its surface density is only about 0.9 g·cm^(−2),reducing by 60%than that of pure *** quantitate relationship between radiation-dose and the materials’thickness was also confirmed to the logistic function when the surface density is in the range of 0.6-1.5 g·cm^(−2).Meantime,the rolling parameters,interface microstructure and mechanical properties in both as-rolled and annealing treated samples were *** sheets possess a special dissimilar atoms diffusion transitional zone containing an obvious inter-diffusion Mg-Al interface and the unique micro-corrugated Ta-Al interface,as well as a thin Al film with a thickness of about 10μ*** special zone could reduce the stress concentration and enhance the strength of Mg-Ta-Al *** interface bonding strength reaches up to 54-76 *** ultimate tensile strength(UTS)and yield strength(TYS)of the Mg-Ta-Al sheet were high to 413 MPa and 263 MPa,respectively,along with an elongation of 5.8%.The molecular dynamics(MD)analysis results show that the two interfaces exhibit different formation mechanism,the Mg-Al interface primarily depended on Mg/Al atoms diffusion basing point defects movement,while the Ta-Al interface with a micro-interlock pining shape formed by close-packed planes slipping during high temperature strain-induced deformation process.

关键词： Dissimilar metals composites Mg based alloys Radiation shielding Hot rolling Lightweight

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高性能高聚物黏结炸药压制成型研究进展与展望

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中国机械工程 2024年第1期35卷 160-180页

作者：孙海涛詹梅樊晓光郭靖韩超张君西北工业大学材料学院西安710072 中国工程物理研究院化工材料研究所绵阳621900 中国重型机械研究院股份公司金属挤压与锻造装备技术国家重点实验室西安710032

压装型高聚物黏结炸药(PBX)因具有优异的爆轰性能和力学性能而被广泛应用于现代高效毁伤武器战斗部。未来作战环境和战略需求的不断变化,促使压装型PBX朝着高质量、高安全、高效率成型制造的方向发展。综述了压装型PBX在成型质量与性能... 详细信息

压装型高聚物黏结炸药(PBX)因具有优异的爆轰性能和力学性能而被广泛应用于现代高效毁伤武器战斗部。未来作战环境和战略需求的不断变化,促使压装型PBX朝着高质量、高安全、高效率成型制造的方向发展。综述了压装型PBX在成型质量与性能调控、压制安全性、自动化制造三方面的相关研究现状及面临的问题。首先探讨了PBX在成型质量与性能调控方面的研究进展,包括炸药颗粒致密化演变规律与密度均匀性、损伤演化机制与界面性能调控、残余应力检测与调控;进而分析讨论了PBX的压制安全性以及在数字化和自动化制造方面的研究现状;最后基于对研究现状的分析,展望了PBX压制成型领域未来的发展趋势与面临的挑战。

关键词：高聚物黏结炸药压制成型成型质量安全性数字化

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A Review on Ultrasonic-Assisted Forming:Mechanism,Model,and Process

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Chinese Journal of Mechanical Engineering 2021年第5期34卷 147-170页

作者： Guangda Shao Hongwei Li mei zhan Shaanxi Key Laboratory of Precision Forming Technology and Equipment School of Materials Science and Engineering Northwestern Polytechnical University Xi’an China

Compared with conventional forming processes,ultrasonic-assisted forming technology with a high frequency and small amplitude can significantly improve the forming quality of *** to the advantages of reduced forming force,improved surface quality,avoidance of forming defects,and strengthened surface structure,ultrasonic-assisted forming technology has been applied to increasingly advanced forming processes,such as incremental forming,spinning,and ***,in the ultrasonic-assisted forming process,there are multiple ultrasonic mechanisms,such as the volume effect and surface *** explanation of the effect of ultrasonic vibration(UV)on plastic deformation remains controversial,hindering the development of related ***,many researchers have proposed many new theories and technologies for ultrasonic-assisted *** summarize these developments,systematic discussions on mechanisms,theoretical models,and forming performances are provided in this *** this basis,the limitations of the current study are *** addition,an outlook for ultrasonic-assisted forming is proposed:efficient and stable UV systems,difficulty forming components with complex geometry,explanation of the in-depth mechanism,a systematic theoretical prediction model,and multi-field-coupling energy-assisted forming are considered to be hot spots in future *** present review enhances existing knowledge of ultrasonic-assisted forming,and facilitates a fast reference for related researchers.

关键词： Ultrasonic vibration Forming Mechanism Model Processing performance

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数智融合发展赋能制造业企业绿色技术创新的影响研究

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价值工程 2024年第2期43卷 14-16页

作者：黎丹占美玲湖南工商大学经济与贸易学院长沙410205

本文利用2010-2020年沪深A股制造业上市企业的面板数据,实证检验数智融合发展对绿色技术创新的影响机制。研究发现:数智融合发展能够促进制造业企业绿色技术创新的提升;数智融合发展主要通过提高制造业企业人力资本水平和增加研发资源... 详细信息

本文利用2010-2020年沪深A股制造业上市企业的面板数据,实证检验数智融合发展对绿色技术创新的影响机制。研究发现:数智融合发展能够促进制造业企业绿色技术创新的提升;数智融合发展主要通过提高制造业企业人力资本水平和增加研发资源投入两个作用机制促进绿色技术的创新水平。

关键词：数智融合绿色技术创新人力资本研发投入

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A Numerical-analytic Method for Quickly Predicting Springback of Numerical Control Bending of Thin-walled Tube

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Journal of Materials Science & Technology 2006年第5期22卷 713-720页

作者： mei zhan He YANG Liang HUANG College of Materials Science and Engineering Northwestern Polytechnical University Xi＇an 710072 China

Springback is one of important factors influencing the forming quality of numerical control （NC） bending of thin-walled tube. In this paper, a numerical-analytic method for springback angle prediction of the process was put forward. The method is based on springback angle model derived using analytic method and simulation results from three-dimensional （3D） rigid-plastic finite element method （FEM）. The method is validated through comparison with experimental results. The features of the method are as follows：（1） The method is high in efficiency because it combines advantages of rigid-plastic FEM and analytic method. （2） The method is satisfactory in accuracy, since the field variables used in the model is resulting from 3D rigid-plastic FEM solution, and the effects both of axial force and strain neutral axis shift have been included. （3） Research on multi-factor effects can be carried out using the method due to its advantage inheriting from rigid-plastic FEM. The method described here is also of general significance to other bending processes.

关键词： Thin-walled tube Numerical control bending Springback Numerical-analytic method 3D rigid-plastic FEM

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Advances and trends in plastic forming technologies for welded tubes

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Chinese Journal of Aeronautics 2016年第2期29卷 305-315页

作者： zhan mei Guo Kun Yang He State Key Laboratory of Solidification Processing School of Materials Science and EngineeringNorthwestern Polytechnical University

With the implementation of environmental protection, sustainable development and conservation-oriented policies, components and parts of thin-walled welded tubes have gained increasing application in the aircraft and automotive industries because of their advantages： easily achieving forming and manufacturing process at low cost and in a short time. The current research on welded tube plastic forming is mainly concentrated on tube internal high-pressure forming, tube bending forming, and tube spinning forming. The focuses are on the material properties and char- acterization of welded tubes, finite element modeling for welded tube forming, and inhomogeneous deformation behavior and the mechanism and rules of deformation coordination in welded tube plastic forming. This paper summarizes the research progress in welded tube plastic forming from these aspects. Finally, with a focus on the urgent demand of the aviation, aerospace and automotive industries for high-strength and light-weight tubes, this paper discusses the development trends and challenges in the theory and technology of welded tube plastic forming in the future. Among them, laser tailor-welded technology will find application in the manufacture of high-strength steel tubes. Tube-end forming technology, such as tube flaring and flanging technology, will expand its appli- cation in welded tubes. Therefore, future studies will focus on the FE modeling regarding how to consider effects of welding on residual stresses, welding distortions and microstructure, the inhomo- geneous deformation and coordination mechanism of the plastic forming process of tailor-welded tubes, and some end-forming processes of welded tubes, and more comprehensive research on the formin~ mechanism and limit of welded tubes.

关键词： Constraint effects Deformation coordination Finite element modeling Forming Forming limit Inhomogeneous deforma-tion Material characteristics Welded tube

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Dependence on forming parameters of an integral panel during the electromagnetic incremental forming process

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Chinese Journal of Aeronautics 2018年第7期31卷 1625-1634页

作者： Jinqiang TAN mei zhan Hongwei LI State Key Laboratory of Solidification Process School of Materials Science & Engineering Northwestern Polytechnical University

Nowadays, more and more attentions are paid to electromagnetic incremental forming（EMIF）, especially for a part with a large-scale size, e.g., an integral panel with stiffened ribs. In this work, the bending of a panel into a double-curvature profile via EMIF is carried out experimentally and evaluated by comparing the formed profile with the desired profile. During the process,discharges at four positions along different discharge paths are designed. The effects of forming parameters on the die-fittingness of the workpiece are discussed, for which two evaluation indices are used to judge forming results. The results show that a discharge voltage in an incremental mode is helpful to improve the fittingness and avoid the collision rebound against the die at the same *** at the diagonal positions with the ‘‘X＂ discharge path exhibits the minimal shape deviation and the best forming uniformity. On the contrary, discharging at the parallel positions with the ‘‘Z＂ discharge path obtains the worst forming quality. Overlap of the coil at different positions should be given during EMIF; however, a lower overlap rate of the coil helps improve the forming quality. The results obtained in this work are useful for forming integral panels with stiffened ribs via the EMIF process.

关键词： Electromagnetic incrementalforming (EMIF) Forming uniformity Integral panel Parameters Shape deviation

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A Method of Obtaining Deformation Information by Tracing Deformation from Sections for 3D FE Simulation

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Journal of Materials Science & Technology 2003年第z1期19卷 65-68页

作者： mei zhan He YANG Yuli LIU College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China

With the development of computer technology and finite element method, the priority research area of plasticforming has focused on 3D FE simulation of forming processes for components with complicated geometrical *** processes have complex deforming mechanism, and different sections have different deforming ***, for making a simple, convenient, and practical analysis of its deforming law, how to obtain deformationinformation of key sections from the results of 3D FE simulation has become one of problems urgently to be ***, a method of obtaining deformation information by tracing deformation from sections for 3D FE simulation hasbeen proposed. From the deformation information got by this method, the deformation law of key locations and thewhole deforming body can be obtained. This method can also help to compare the result from FE simulation withthat from physical modeling. Key procedures of this method have been presented in detail, and it has been testedby applying to 3D FE simulation of precision forging of the blade with a damper platform. The result shows thatthe method is practicable and reliable, and it can also be applied to 3D FE simulation of plastic forming processes ofother components.

关键词： Plastic forming, 3D FE simulation, Deformation information

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Prediction of Grain Size for Blade Precision Forging Process under Thermo-Mechanical Coupling

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Journal of Materials Science & Technology 2003年第z1期19卷 156-158页

作者： He YANG Yuli LIU Wang CAI mei zhan College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China

Blade precision forging is a high temperature and large plastic deformation process. Interaction of deformation andheat conduction results in producing large temperature unevenness inside the billet. The unevenness has a greateffect on the mechanical property and microstructure of the forged blade. However, internal quality of the blade isdecided by its microstructure, it is necessary to conduct a research on the microstructure of the blade forging *** a blade with a tenon as an object, its precision forging process is simulated and analyzed using a 3D coupledthermo-mechanical FEM code. And based on the prediction model of Ti-6Al-4V presented by the predecessor, astudy of the evolution of grain size in the forging process is made. The distribution characteristics of grain size intypical sections are obtained under various deformation degrees. This study may provide a base for designing theblade forging process and working out its parameters.

关键词： Blade, Precision forging, Grain size, Prediction

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