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Rare Metals 2016年第3期35卷 223-229页

作者： Liang-gang guo Shuai Zhu he Yang Xiao-guang Fan Fu-long Chen State Key Laboratory of Solidification Processing Northwestern Polytechnical University Xi'an 710072 China Beijing Aeronautical Manufacturing Technology Research Institute Beijing 100024 China Aeronautical Key Laboratory for Plastic Forming Technologies Beijing 100024 China

Temperature rise is a significant factor influencing microstructure during（α＋β） deformation of TA15 titanium *** experiment was designed to explore microstructure evolution induced by temperature rise due to deformation *** experiment was carried out in（α＋β） phase field at typical temperature rise *** microstructures of the alloy under different temperature rise rates were observed by scanning electron microscopy（SEM）.It is found that the dissolution rate of primary equiaxed a phase increases with the increase in both temperature and temperature rise *** the same temperature range,the higher the temperature rise rate is,the larger the final content and grain size of primary equiaxed a phase are due to less dissolution *** quantitatively depict the evolution behavior of primary equiaxed a phase under any temperature rise rates,the dissolution kinetics of primary equiaxed a phase were well described by a diffusion *** model predictions,including content and grain size of primary equiaxed a phase,are in good agreement with experimental *** work provides an important basis for the prediction and control of microstructure during hot working of titanium alloy.

关键词： TA15 titanium alloy Temperature rise Deformation heat Microstructure evolution model

Stable photocurrent-voltage characteristics of perovskite single crystal detectors obtained by pulsed bias

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Chinese Physics B 2024年第4期33卷 209-214页

作者：刘新陈之龙王虎张雯清董昊王鹏祥邵宇川 Laboratory of Thin Film Optics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Materials for High-Power Laser Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Key Laboratory for Ultrafine Materials of Ministry of Education Shanghai Engineering Research Center of Hierarchical NanomaterialsSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China School of Microelectronics Shanghai UniversityShanghai 201899China Hangzhou Institute for Advanced Study University of Chinese Academy of SciencesHangzhou 310024China

Photocurrent-voltage characterization is a crucial method for assessing key parameters in x-ray or y-ray semiconductor detectors,especially the carrier mobility lifetime ***,the high biases during photocurrent measurements tend to cause severe ion migration,which can lead to the instability and inaccuracy of the test *** the mixed electronic-ionic charac teristics,it is imperative to devise novel methods capable of precisely measuring photocurrentvoltage characteristics under high bias conditions,free from interference caused by ion *** this paper,pulsed bias is employed to explore the photocurrent-voltage characteristics of MAPbBr_(3) single *** method yields stable photocurrent-voltage characteristics at a pulsed bias of up to 30 V,proving to be effective in mitigating ion *** fitting the modified hecht equation,we determined the mobility lifetime products of 1.0×10^(2) cm^(2)·V^(-1)for hole and 2.78×10~(-3)cm^(2)·V^(-1)for *** approach offers a promising solution for accurately measuring the transport properties of carriers in perovskite.

关键词： perovskites ion migration pulsed bias mobility lifetime product

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伦理视域下的家庭共同体建设

中州学刊 2024年第5期 101-109页

作者：龙静云贾英飒华中师范大学马克思主义学院湖北武汉430079 华中师范大学政治哲学研究中心湖北武汉430079 包头师范学院马克思主义学院内蒙古包头014031

家庭是社会的细胞,是以婚姻、血缘、收养等关系为纽带,由夫妻、父母、子女、兄弟姐妹等成员构成的一个小型共同体。家庭共同体具有强烈的伦理属性,这主要表现为:家庭共同体是一个亲情共同体,家庭共同体是一个生活共同体,家庭共同体是一... 详细信息

家庭是社会的细胞,是以婚姻、血缘、收养等关系为纽带,由夫妻、父母、子女、兄弟姐妹等成员构成的一个小型共同体。家庭共同体具有强烈的伦理属性,这主要表现为:家庭共同体是一个亲情共同体,家庭共同体是一个生活共同体,家庭共同体是一个文化共同体。调节家庭共同体关系的伦理规范主要包括:以男女平等为原则,以亲子和谐为依循,以奉献国家和社会为目标。建设新时代家庭共同体的策略是:以法治保障家庭共同体建设,以德治引领家庭共同体建设,以家治推进家庭共同体建设,以自治助力家庭共同体建设,由此让每个家庭成员为家庭共同体和中华民族大家庭共同体做出贡献,这也是推进公民道德建设的重要一环。

关键词：家庭共同体伦理属性依循规范

高校青年科研人员学术产出的组态路径研究——基于社会生态系统理论视角

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科学学研究 2024年第6期42卷 1238-1245页

作者：张征谢佳贺伟山西财经大学工商管理学院山西太原030006 西安交通大学管理学院陕西西安710049

科研人员的发展受到所处的整个社会生态系统的影响,然而现有独立效应的研究无法解释其学术产出路径的复杂性。基于社会生态系统理论,本研究从微观、中观、宏观3个系统中识别出6个前因条件,构建了高校青年科研人员学术产出的多重并发机... 详细信息

科研人员的发展受到所处的整个社会生态系统的影响,然而现有独立效应的研究无法解释其学术产出路径的复杂性。基于社会生态系统理论,本研究从微观、中观、宏观3个系统中识别出6个前因条件,构建了高校青年科研人员学术产出的多重并发机制模型,并运用fsQCA方法分析影响青年科研人员学术产出的组态路径。结果发现:不存在引致高校青年科研人员高学术产出的单个必要条件;存在6条可以引发青年科研人员高学术产出的组态路径,根据核心条件的分布特征,可将其归纳为四种类型:自我发展型、团队合作型、环境支持型、要素聚合型。研究成果从社会生态系统视角探讨了多维前因条件对高校青年科研人员学术产出的组态效应,为提升科研人员学术产出提供实践启示。

关键词：学术产出社会生态系统理论 fsQCA 青年科研人员

新时代中华优秀传统美德的创造性转化创新性发展

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思想教育研究 2024年第5期 102-110页

作者：肖贵清龙正午清华大学马克思主义学院北京100084

中华优秀传统美德是中华优秀传统文化的精髓,代表中华优秀传统文化的价值追求。新时代“两个结合”理论创新和中国式现代化实践要求立足中华优秀传统文化根脉,发挥美德价值导向作用,推动中华优秀传统美德创造性转化和创新性发展。通过... 详细信息

中华优秀传统美德是中华优秀传统文化的精髓,代表中华优秀传统文化的价值追求。新时代“两个结合”理论创新和中国式现代化实践要求立足中华优秀传统文化根脉,发挥美德价值导向作用,推动中华优秀传统美德创造性转化和创新性发展。通过个人品德、家庭美德、职业道德、社会公德、为政以德和邦交德义等层面的社会道德建设,挖掘中华优秀传统美德的时代价值。在去粗取精、去伪存真的基础上,推动中华优秀传统美德与马克思主义相结合,为社会主义核心价值观和思想道德建设提供文化滋养,实现中华优秀传统美德的创造性转化和创新性发展。

关键词：新时代中华优秀传统美德两个结合

TSPO deficiency exacerbates acute lung injury via NLRP3 inflammasome-mediated pyroptosis

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Chinese Medical Journal 2024年第13期137卷 1592-1602页

作者： Jingyi Han Xue zha.g Menghua Cai Feng Tian Yi Xu Hui Chen Wei he Jianmin zha.g Hui Tian Department of Thoracic Surgery Qilu Hospital of Shandong UniversityJinanShandong 250012China CAMS Key Laboratory of T Cell and Immunotherapy Department of ImmunologyInstitute of Basic Medical SciencesChinese Academy of Medical Sciences and School of Basic MedicinePeking Union Medical CollegeState Key Laboratory of Medical Molecular BiologyBeijing 100005China Changzhou Xitaihu Institute for Frontier Technology of Cell Therapy ChangzhouJiangsu 213000China Haihe Laboratory of Cell Ecosystem Chinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300020China

Background:Acute respiratory distress syndrome(ARDS)is a common cause of respiratory failure in many critically ill *** inflammasome activation plays an important role in the induction of acute lung injury(ALI)and ARDS,the regulatory mechanism of this process is still *** cells are stimulated by inflammation,the integrity and physiological function of mitochondria play a crucial part in ***,the underlying mechanisms and function of mitochondrial proteins in the process of pyroptosis are largely not yet ***,we identified the 18-kDa translocator protein(TSPO),a mitochondrial outer membrane protein,as an important mediator regulating nucleotide-binding domain,leucine-rich repeat,and pyrin domain-containing protein 3(NLRP3)inflammasome activation in macrophages during ***:TSPO gene knockout(KO)and lipopolysaccharide(LPS)-induced ALI/ARDS mouse models were employed to investigate the biological role of TSPO in the pathogenesis of *** macrophages were used to further characterize the effect of TSPO on the NLRP3 inflammasome *** of NLRP3 inflammasome was preformed through LPS+adenosine triphosphate(ATP)co-stimulation,followed by detection of mitochondrial membrane potential,reactive oxygen species(ROS)production,and cell death to evaluate the potential biological function of *** between two groups were performed with a two-sided unpaired ***:TSPO-KO mice exhibited more severe pulmonary inflammation in response to LPS-induced *** deficiency resulted in enhanced activation of the NLRP3 inflammasome pathway,promoting more proinflammatory cytokine production of macrophages in LPS-injured lung tissue,including interleukin(IL)-1β,IL-18,and macrophage inflammatory protein(MIP)-*** in TSPO-KO macrophages tended to depolarize in response to cellular *** increased production of mitochondrial damage-associated molecular pattern led to enhanced mitochondrial membr

关键词： Acute respiratory distress syndrome Acute lung injury 18-kDa translocator protein Macrophage NLRP3 inflammasome Inflammation

Fat deposition deficiency is critical for the high mortality of pre-weanling newborn piglets

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Journal of Animal Science and Biotechnology 2018年第4期9卷 917-924页

作者： Ting he long he Enen gao Jinhua Hu Jianjun Zang Chunlin Wang Jinshan zhao Xi Ma State Key Laboratory of Animal Nutrition College of Animal Science and Technology China Agricultural University College of Animal Science and Technology Qingdao Agricultural University Department of Internal Medicine Department of Biochemistry University of Texas Southwestern Medical Center

Background: The high mortality of pre-weanling piglets is a dominant challenge which severely restricts the development of pig industry. A number of factors including nutrients imbalance and temperature variation during postnatal period of piglets have been reported to closely associated with the high mortality of postnatal *** study aims to find out the relationship between fat deposition and survival of newborn ***: There were no differences in organ coefficient and bone density between the surviving and dead piglets(P > 0.05). The body weight and the fat deposition in the dead piglets were lower than the live individuals(P he average sizes of white adipocytes in back and abdominal adipose tissues of dead piglets were smaller than the survivals(P he protein expression levels of adipocyte differentiation markers PPARγ and C/EBPα in the back and abdominal adipose tissues were lower in dead piglets compared to live piglets. The mRNA expressions of thermogenic markers PgC1α and PRDM16 in adipose tissues were decreased in the dead piglets(P he microarray of back fat samples from the surviving and dead piglets were conducted; two down-regulated genes namely AAMDC and CASTOR1 were identified from the dead piglets. According to quantitative real-time PCR(RT-PCR) analysis, the mRNA expression of AAMDC decreased, whereas CASTOR1 expression elevated in the dead piglets compared to the surviving piglets(P he fat deposition and adipocyte differentiation in the dead piglets are insufficient compared to the surviving piglets, which may attenuate the thermogenic ability of white adipose tissue(WAT). Our data indicate that fat deposition in newborn piglets is vital to their survival.

关键词： Fat deposition Mortality Pre-weanling piglets Thermogenesis White adipose tissue

超级数字平台私权力的生成、风险及规制——基于公私二象性视角

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财经问题研究 2024年第7期 74-87页

作者：李凌寒冯彦龙安徽大学经济学院安徽合肥230601 澳门大学宪法与基本法研究中心中国澳门999078

在以数字智能技术为驱动的社会转型背景下,公共性生产不再局限于政府等传统公共机构的参与,而是在主体与领域的扩展中形成了数字异化的态势,超级数字平台便是其中之一。以此为背景,基于开放共享的网络效应,超级数字平台的公共性逐渐形成... 详细信息

在以数字智能技术为驱动的社会转型背景下,公共性生产不再局限于政府等传统公共机构的参与,而是在主体与领域的扩展中形成了数字异化的态势,超级数字平台便是其中之一。以此为背景,基于开放共享的网络效应,超级数字平台的公共性逐渐形成;基于服务依赖的权利让渡,超级数字平台逐渐获得话语权;基于技术优势的双重控制,超级数字平台的私权力得以生成与演进。对超级数字平台私权力进行解构发现,其可能产生算法技术的滥用、合同机制的失效、用户权利的忽视等对私主体的风险,从而引起私法保护核心的坍塌;也将导致政府监管难度增加、垄断地位形成、公共利益受损,进而对公权力产生影响,导致公法规制逻辑的紊乱。因此,应当尝试以公私主体关系为路径对超级数字平台私权力进行规制:一方面,通过格式合同的协同规制、侵权规则的更新解释、私力救济的条款重视等贯彻以私法为核心的意思自治。另一方面,通过明确私权力的责任与义务、监管数字内容与技术应用、保障协议规则的客观公平等再造公益保障的公法逻辑。

关键词：超级数字平台私权力公共性生产公私二象性数字治理

The AVO Effect of Formation Pressure on Time-Lapse Seismic Monitoring in Marine Carbon Dioxide Storage

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哈尔滨工程大学学报（英文版） 2024年第3期23卷 645-655页

作者： Fan Wu Qingping Li Yufa he Jingye Li Beijing Huairou Laboratory Beijing 101499China China National Offshore Oil Corporation Research Institute Co.Ltd Beijing 100027China China University of Petroleum-Beijing Beijing 102249China

The phase change of CO_(2) has a significant bearing on the siting, injection, and monitoring of storage. The phase state of CO_(2) is closely related to pressure. In the process of seismic exploration, the information of formation pressure can be response in the seismic data. Therefore, it is possible to monitor the formation pressure using time-lapse seismic method. Apart from formation pressure, the information of porosity and CO_(2) saturation can be reflected in the seismic data. here, based on the actual situation of the work area, a rockphysical model is proposed to address the feasibility of time-lapse seismic monitoring during CO_(2) storage in the anisotropic formation. The model takes into account the formation pressure, variety minerals composition, fracture, fluid inhomogeneous distribution, and anisotropy caused by horizontal layering of rock layers(or oriented alignment of minerals). From the proposed rockphysical model and the well-logging, cores and geological data at the target layer, the variation of P-wave and S-wave velocity with formation pressure after CO_(2) injection is calculated. And so are the effects of porosity and CO_(2) saturation. Finally, from anisotropic exact reflection coefficient equation, the reflection coefficients under different formation pressures are calculated. It is proved that the reflection coefficient varies with pressure. Compared with CO_(2) saturation, the pressure has a greater effect on the reflection coefficient. Through the convolution model, the seismic record is calculated. The seismic record shows the difference with different formation pressure. At present, in the marine CO_(2) sequestration monitoring domain, there is no study involving the effect of formation pressure changes on seismic records in seafloor anisotropic formation. This study can provide a basis for the inversion of reservoir parameters in anisotropic seafloor CO_(2) reservoirs.

关键词： Time-lapse seismic monitoring Marine carbon dioxide storage AVO modeling Formation pressure Anisotropic Rockphysical model

Potential regulatory mechanism and clinical significance of synaptotagmin binding cytoplasmic RNA interacting protein in colorectal cancer

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World Journal of Clinical Oncology 2024年第11期15卷 1412-1427页

作者： Hui Li he-Qing Huang Zhi-guang Huang Rong-Quan he Ye-Ying Fang Rui Song Jia-Yuan Luo Da-Tong Zeng Kai Qin Dan-Ming Wei gang Chen Department of Colorectal and Anal Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Pathology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Medical Oncology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Radiotherapy The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Radiology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Pathology Redcross Hospital of Yulin CityYulin 537000Guangxi Zhuang Autonomous RegionChina

BACKgROUND Colorectal cancer(CRC)causes many deaths *** binding cytoplasmic RNA interacting protein(SYNCRIP)is an RNA-binding protein that plays an important role in multiple cancers by epigenetically targeting some *** study will examine the expression,potential effect,biological function and clinical value of SYNCRIP in *** To examine the expression,potential effect,biological function and clinical value METHODS The expression of SYNCRIP was examined by immunohistochemistry arrays and high-throughput *** effect of SYNCRIP gene in CRC cell growth was evaluated by CRISPR-Cas9 *** target genes of SYNCRIP were calculated using various algorithms,and the molecular mechanism of SYNCRIP in CRC was explored by mutation analysis and pathway *** clinical value of SYNCRIP in prognosis and radiotherapy was revealed via evidence-based medicine *** The protein and mRNA levels of SYNCRIP were both highly expressed in CRC samples compared to nontumorous tissue based on 330 immunohistochemistry arrays and 3640 CRC *** grew more slowly in eleven CRC cell lines after knocking out the SYNCRIP *** could epigenetically target genes to promote the occurrence and development of CRC by boosting the cell cycle and affecting the tumor *** addition,CRC patients with high SYNCRIP expression are more sensitive to *** SYNCRIP is upregulated in CRC,and highly expressed SYNCRIP can accelerate CRC cell division by exerting its epigenetic regulatory *** addition,SYNCRIP is expected to become a potential biomarker to predict the effect of radiotherapy.

关键词： Synaptotagmin binding cytoplasmic RNA interacting protein Colorectal cancer Radiotherapy Cell mitosis Immune microenvironment