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西安航空学院学报 2013年第4期31卷 17-19页

作者：张雷西安航空学院外语与旅游系陕西西安710077

"美丽中国"作为一个新的时代名词,赋予了丰富的政治、经济、文化与社会内涵,站在人文主义的角度,解析它的美学价值与思想内涵,进而更好认识"美丽中国"的历史意义和时代主旨。

关键词：美丽中国美学价值思想内涵

微信群作为教学管理平台在心内科实习生医患沟通技能培养中的应用研究

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中国卫生产业 2018年第31期15卷 197-198页

作者：王蕾四川省德阳市人民医院四川德阳618000

临床实习是医学生走向医学道路必不可少的关键环节,在整个实习过程中医患沟通是最普通且最需要注意的环节。为了提升医学实习生在医患交流中的语言表达能力和表达技巧,该文将微信群这一交流形式带入到临床实习的教学课堂中,建立起通过... 详细信息

临床实习是医学生走向医学道路必不可少的关键环节,在整个实习过程中医患沟通是最普通且最需要注意的环节。为了提升医学实习生在医患交流中的语言表达能力和表达技巧,该文将微信群这一交流形式带入到临床实习的教学课堂中,建立起通过微信群来与患者进行交流的教学管理系统,对以微信群为医学实习生的医患交流平台的技能培养进行研究。

关键词：临床实习医患沟通技能培养

Rapid analysis of fifteen sulfonamide residues in pork and fish samples by automated on-line solid phase extraction coupled to liquid chromatography–tandem mass spectrometry

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Food Science and Human Wellness 2020年第4期9卷 363-369页

作者： Junmei Ma Sufang Fan lei Sun Liangna He Yan zh.ng Qiang Li Hebei Key Laboratory of Forensic Medicine College of Forensic MedicineHebei Medical UniversityShijiazhuang 050017China Hebei Food Safety Key Laboratory Hebei Food Inspection and Research InstituteShijiazhuang 050227China

The aim of this work was to develop an automated on-line solid phase extraction(SPE)with liquid chromatography-tandem mass spectrometry method for the detection of fifteen sulfonamides in pork and fish *** were extracted with 0.2%formic acid acetonitrile solution,purified by on-line SPE device with HLB column,then separated by XBridge C18 column,using 0.1%formic acid solution and acetonitrile as the mobile *** spectrometric data was acquired under multiple reaction monitoring(MRM)mode using positive ionization *** standard method was used in the quantification,good linear relationship was got in range of 0.1–100 ng/mL and correlation coefficient was higher than *** limits of detection were in the range of 0.125–2.00g/kg and the limits of quantitation were in the range of 0.250–5.00g/*** of the method were in range of 78.3%–99.3%,relative standard deviation were lower than 10%.The method was simple,sensitivity,and could be used for routine supervision and analysis of fifteen sulfonamides in pork and fish.

关键词： Liquid chromatography–tandem mass spectrometry On-line solid phase extraction Sulfonamides Internal standard quantification

Achieving Efficient Thick Film All-polymer Solar Cells Using a Green Solvent Additive

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Chinese Journal of Polymer Science 2020年第4期38卷 323-331,I0005页

作者： zhen-Ye Li Wen-Kai zh.ng lei Ying Ning Li Feng Liu Fei Huang Yong Cao Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and DevicesSouth China University of TechnologyGuangzhou 510640China South China Institute of Collaborative Innovation Dongguan 523808China Institute of Materials for Electronics and Energy Technology(i-MEET) FAU Erlangen-Nurnberg91058 ErlangenGermany Department of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai200240China

Adva nces in orga nic photovoltaic tech no logies have been geared toward industrial high-throughput printing manufacturing,which requires in sensitivity of photovoltaic performance reg a rd i ng to the light-harvesting layer ***,the thickness of light-harvesti ng layer for all polymer solar cells(all-PSCs)is often limited to about 100 nm due to the dramatically decreased fill factor upon increasing film thickness,which hampers the light harvesting capability to in crease the power con versio n efficie ncy,and is un favorable for fabricating large-area *** we dem on strate that by tuning the bulk heterojuncti on morphology using a non-halogenated solvent,cyclopentyl methyl ether,in the presence of a gree n solve nt additive of dibenzyl ether,the power con versio n efficie ncy of all-PSCs with photoactive layer thick nesses of over 500 nm reached an impressively high value of 9%.The gen eric applicability of this gree n solvent additive to boost the power conversion efficiency of thick-film devices is also validated in various bulk heterojunction active layer systems,thus representing a promising approach for the fabrication of all-PSCs toward industrial production,as well as further commercialization.

关键词： Thick-film all-polymer solar cell Gree n solve nt additive Dibenzyl ether

Development of a UHPLC-MS/MS method for the quantification of ilaprazole enantiomers in rat plasma and its pharmacokinetic application

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Journal of Pharmaceutical Analysis 2020年第6期10卷 617-623页

作者： Fengting Ou Ying zhou Jinxiu lei Su Zeng Fuhai Wu Ning zh.ng Lushan Yu Institute of Drug Metabolism and Pharmaceutical Analysis College of Pharmaceutical SciencesZhejiang UniversityHangzhou310058China School of Pharmacy Guangdong Pharmaceutical UniversityGuangdong510006China School of Public Health Guangdong Pharmaceutical UniversityGuangdong510006China Institute of Nuclear Agricultural Sciences Zhejiang UniversityHangzhou310058China

In Korea and China,ilaprazole is a widely used proton pump inhibitor in the treatment of gastric *** this study,a specific and sensitive LC-MS/MS method has been developed and validated for the quantification of ilaprazole enantiomers in the rat plasma,using R-lansoprazole as the internal *** enantioseparation was achieved on a CHIRALPAK AS-RH column(4.6 mm×150 mm,i.d.5 mm),with a mobile phase composed of 10 m M ammonium acetate aqueous solution and acetonitrile(60:40,V/V),at a flow-rate of 0.5 m L/*** method was validated over the concentration range of 0.5 e300 ng/m L for both,R-and *** lower limit of quantification was 0.5 ng/m L for both *** relative standard deviation(RSD)of intra-and inter-day precision of R-ilaprazole and S-ilaprazole was less than 10.9%,and the relative error accuracy(RE)ranged fromà0.5%e2.0%.Finally,the method was successfully evaluated in rats in a stereoselective pharmacokinetic study of the ilaprazole racemate.

关键词： Ilaprazole Enantiomer LC-MS/MS Pharmacokinetics

十二指肠镜下乳头括约肌切开术后胆总管结石复发的手术治疗

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中国普通外科杂志 2014年第8期23卷 1136-1138页

作者：周宗庆傅志红雷慧菁浙江省龙游县人民医院外一科浙江龙游324400

目的:探讨十二指肠镜下乳头括约肌切开术(EST)后胆总管结石复发的手术方式。方法:回顾性分析2007年—2013年共收治的EST术后胆总管结石复发25例患者临床资料,所有患者均采取了手术治疗,其中行肝叶切除+胆肠吻合术1例,肝叶切除+胆总管切... 详细信息

目的:探讨十二指肠镜下乳头括约肌切开术(EST)后胆总管结石复发的手术方式。方法:回顾性分析2007年—2013年共收治的EST术后胆总管结石复发25例患者临床资料,所有患者均采取了手术治疗,其中行肝叶切除+胆肠吻合术1例,肝叶切除+胆总管切开取石2例,胆肠吻合术12例,胆总管切开取石6例,胆总管与十二指肠侧侧吻合术2例,再行EST 2例。结果:全组无死亡,并发症发生率为20.0%,残余结石发生率为16.0%,治愈好转率达100%。结论:胆肠吻合术是处理EST术后胆总管结石复发的最佳选择。

关键词：胆总管结石外科学乳头括约肌切开术胆肠吻合术

Reactive protein, plasminogen activator inhibitor type-1 （PAI-1） levels, PAI-1 promoter 4G/5G polymorphism and acute myocardial infarction

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Journal of Geriatric Cardiology 2010年第3期7卷 147-151页

作者： Xue-lei Cao Chang-Yong zhou lei Yin Shao-Chun Wang Xiu-Ling Jia Huan Huang Xiao-Hong Sun Qingdao University Medical College Qingdao266003China Emergency Department Affiliated Hospital of Qingdao University Medical College Qingdao 266003 China.

Objective To investigate the relationship between CRP, plasminogen activator inhibitor type 1 （PAI-1） levels, PAI-1 gene promoter 4G/5G polymorphism and the type of acute myocardial infarction （ST elevation myocardial infarction, STEMI vs the non-ST elevation Myocardial infarction, NSTEMI）. Methods One hundred seventy-six consecutive patients with AMI were included for the study, of whom 60 had STEMI and 56 had NSTEMI, and 60 adults without cardiovascular and cerebrovascular disease were selected as controls. Blood samples were obtained from patients within 6 h of AMI and the plasma PAI-1, CRP, and the gene polymorphism were measured. Results Plasma levels of PAI- 1 and CRP were higher in AMI groups, compared those in the control group, and plasma levels of PAI-1 were significantly higher in patients with STEMI compared to those with NSTEMI （80.12ng/ml VS.73.01ng/ml, P 〈0.01）, while CRP levels were not significantly different between patient with STEMI and NSTEMI （3.87 ± 0.79 mg/ml VS.4.01 ±0.69mg/ml, P〉0.05）. PAI-1 levels presented a significant correlation with CRP levels in the NSTEMI subjects. However, PAI-1 and CRP levels could explain the lack of a significant relationship between them in control and STEMI *** frequencies of 4G/4G genotype in the AMI group were higher than those in the control group and higher in patient with STEMI than in patient with NSTEMI. Plasma levels of PAI-1 in subjects with 4G/4G genotype were significantly increased as compared to those in subjects with 4G/5G and 5G/5G genotype. Conclusions Plasma PAI-1 levels were associated with different myocardial infarction type, and PAI-1 promoter 4G/5G polymorphisms and CRP may be related to plasma PAI-1 levels

关键词： ST-segment elevation myocardial infarction non-ST segment elevation myocardial infarction Plasminogen activatorinhibitor- 1 C-reactive protein

Chemical characteristics of PM_(2.5) during haze episodes in the urban of Fuzhou,China

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Particuology 2013年第3期11卷 264-272页

作者： Fuwang zh.ng Lingling Xu Jinsheng Chen Xiaoqiu Chen zhenchuan Niu Tong lei Chunming Li Jinping zhao Key Lab of Urban Environment and Health Institute of Urban EnvironmentChinese Academy of Sciences Graduate University of Chinese Academy of Sciences Environmental Monitoring Center of Fujian Environmental Monitoring Center of Guangdong

Atmospheric fine particles （PM2.5） were collected in this study with middle volume samplers in Fuzhou, China, during both normal days and haze days in summer （September 2007） and winter （january 2008）. The concentrations, distributions, and sources of polycyclic aromatic hydrocarbons （PAHs）, organic carbon （OC）, elemental carbon （EC）, and water soluble inorganic ions （WSIls） were determinated. The results showed that the concentrations of PM2.s, PAHs, OC, EC, and WSIIs were in the orders of haze 〉 normal and winter〉 summer. The dominant PAHs of PM2.s in Fuzhou were Fluo, Pyr, Chr, BbF, BkF, BaP, BghiP, and IcdP, which represented about 80.0% of the total PAHs during different sampling periods. The BaPeq concentrations of ^-~PAHs were 0.78, 0.99, 1.22, and 2.43 ng/m3 in summer normal, summer haze, winter normal, and winter haze, respectively. Secondary pollutants （SO42 , NO3 , NH4＊, and OC） were the major chemical compositions of PM2.5, accounting for 69.0%, 55.1%, 63.4%, and 64.9% of PM2.s mass in summer normal, summer haze, winter normal, and winter haze, respectively. Correspondingly, secondary organic carbon （SOC） in Fuzhou accounted for 20.1%, 48.6%, 24.5%, and 50.5% of OC. The average values of nitrogen oxidation ratio （NOR） and sulfur oxidation ratio （SOR） were higher in haze days （0.08 and 0.27） than in normal days （0.05 and 0.22）. Higher OC/EC ratios were also found in haze days （5.0） than in normal days （3.3）. Correlation analysis demonstrated that visibility had positive correlations with wind speed, and neg- ative correlations with relative humidity and major air pollutants. Overall, the enrichments of PM2.5, OC, EC, SO42 ,andNO3 promoted haze formation. Furthermore, the diagnostic ratios of IcdP/（IcdP ＋ BghiP）, lcdP/BghiP, OC/EC, and NO3 /SO42 indicated that vehicle exhaust and coal consumption were the main sources of pollutants in Fuzhou.

关键词： Fine particles Haze Polycyclic aromatic hydrocarbons Organic carbon Elemental carbon Water soluble inorganic ions

Tunable nitrogen crafted 2D-graphene nano-hybrid from industrial expansive and ecological approach as robust cathode microporous layer to improve performance of a direct methanol fuel cell

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Science China(Technological Sciences) 2023年第9期66卷 2669-2680页

作者： BALAKRISHNAN Prabhuraj GUAN Li LIU HuiYuan LEUng PuiKi SHAH Akeel XIng lei SU HuaNeng XU Qian Institute for Energy Research Jiangsu UniversityZhenjiang 212013China School of Energy and Power Engineering Chongqing UniversityChongqing 400030China Department of Chemical Process Engineering University of SurreyGuildford GU27XHUK

In this work, the excess water-stagnation issue in the high current region in direct methanol fuel cells(DMFCs) is resolved by using atomic precision modulated nitrogen-crafted graphene(ng) in the cathode microporous layer by utilizing simplistic,industrial-expansive and ecological strategy. Few-layer 2D-graphene(~2–5 nm thickness) is prepared by bath sonication approach from abundant feedstock-graphite and is treated with nitric acid to yield 1.8 wt.% uniformly dispersed nitrogen containing ng. Specifically, 1:4 weight ratio ng:carbon-black(CB) hybrid architecture, displays 0.252 V in 370 mA cm^(-2) with the peak power density of 93.4 mW cm^(-2), improving cell power density by 45.6% compared with standard one at 60℃ and 1 mol/L methanol/oxygen conditions at ultra-low catalyst loadings and displaying exceptional stability. Atomic insights into ng reveal that interplay between bonding configurations, altered hydrophobic/hydrophilic porosity of graphene(10.6% less wettability from contact angle and 13.1% high electrode porosity measurements) contribute to the better mass-transport-porogenic effect(16.3% high oxygen-permeability), mildly affecting the electron pathway(6.5% reduced in-plane electrical conductivity),overall significantly improving cell performance. Altogether, this work delivers multiple advantages, i.e., the usage of material from facile, sustainable and cost-effective routes, while improving DMFC performance with potential industrial promise.

关键词： direct methanol fuel cells(DMFCs) membrane electrode assembly(MEA) 2D materials liquid phase exfoliation nitrogen doping

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Selenium distribution and nitrate metabolism in hydroponic lettuce(Lactuca sativa L.): Effects of selenium forms and light spectra

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Journal of Integrative Agriculture 2020年第1期19卷 133-144页

作者： BIAN zh.ng-hua lei Bo CHEng Rui-feng WAng Yu LI Tao YAng Qi-chang Institute of Environment and Sustainable Development in Agriculture Chinese Academy of Agricultural SciencesBeijing 100081P.R.China School of Animal Rural and Environmental SciencesNottingham Trent UniversityBrackenhurst CampusNG250QFUK

A deficiency in selenium(Se) in the human diet is a worldwide problem. The intake of Se-rich vegetables can be a safe way to combat Se deficiency for humans. However, most leafy vegetables can accumulate a high content of nitrates, which poses a potential threat to human health. Light is an important environmental factor that regulates the uptake and distribution of mineral elements and nitrogen metabolism in plants. However, the effects of Se forms and light conditions, especially light spectra, on the uptake and translocation of Se and on nitrate reduction are poorly understood. In this study, lettuce(Lactuca sativa L.) was treated with exogenous Se applied as selenate(10 mmol L^-1) and selenite(0.5 mmol L^-1) and grown under five different light spectra: fluorescent light(FL), monochromatic red LED light(R), monochromatic blue LED light(B), and mixed red and blue LED light with a red to blue light ratio at 4(R/B=4), 8(R/B=8), and 12(R/B=12), respectively. The effects of light spectra and Se forms on plant growth, photosynthetic performance, Se accumulation and nitrate reduction were investigated. The results showed that the light spectra and Se forms had significant interactions for plant growth, foliar Se accumulation and nitrate reduction. The Se concentration and nitrate content in the leaves were negatively correlated with the percentage of red light from the light sources. Compared to Se applied as selenite, exogenous Se applied as selenate was more effective in reducing nitrate via promoting nitrate reductase and glutamate synthase activities. The lowest nitrate content and highest plant biomass were observed under R/B=8 for both the selenate and selenite treatments. The significant effect of the light spectra on the root concentration factor and translocation factor of Se resulted in marked variations in the Se concentrations in the roots and leaves. Compared with FL, red and blue LED light led to significant decreases in the foliar Se concentration. The r

关键词： selenium light spectra nitrates nitrogen metabolism enzymes LEDs Lactuca sativa L.