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闽北方言的调值与"弱化声母"的拟测

方言 2004年第1期26卷 54-75页

作者： zev Handel 陈宝贤 Departmet of Asian Languages and Literature University of WashingtonSeattle 北京大学中文系 2002级博士生北京100871

罗杰瑞所拟测的原始闽语"弱化声母"而分化出的闽北方言的声调,从相关调型的音高来看,遵循了完全一致的类型。本文证明,该音高类型不可能解释为借入或层次造成的。它构成了支持罗杰瑞拟音的强有力证据,同时也为确定"弱化"声母的语音实质... 详细信息

罗杰瑞所拟测的原始闽语"弱化声母"而分化出的闽北方言的声调,从相关调型的音高来看,遵循了完全一致的类型。本文证明,该音高类型不可能解释为借入或层次造成的。它构成了支持罗杰瑞拟音的强有力证据,同时也为确定"弱化"声母的语音实质提供了依据。本研究涉及八个闽北方言的材料,其中之一是本文首次描写的。文章证明,其中的某些方言构成了源头上有联系的土语群,该土语群的原始声调系统(包括绝对音高值)可以有把握地构拟。通过进一步的比较,整个原始闽北语的声调系统也可以构拟出来。原始闽北语具有八个调类和三套发音方法不同的塞音、塞擦音声母。根据声调的音高模式和普遍音理,本文将与罗杰瑞原始闽语"弱化声母"相对应的原始闽北语的声母,构拟为伴有气嗓音除阻的浊声母。

关键词：闽北方言调值声母音高声调

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Premorbid Use of Clopidogrel Portends Worse Outcomes in Patients Treated Surgically for Intracranial Hemorrhage

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Open Journal of Modern Neurosurgery 2014年第4期4卷 173-180页

作者： Eric Marvin Aaron Danison Greg Davis zev Elias Gary Simonds Virginia Tech Carilion Clinic Virginia Tech Carilion School of Medicine Roanoke Virginia USA

Background: Widespread use of antiplatelet and anticoagulation medications (APACs) can be a difficult challenge in the presence of a neurosurgical emergency. Premorbid use of APACs, particularly clopidogrel, has been shown to affect outcomes in patients with stroke and traumatic brain injury. Objective: We hypothesized that pre-morbid clopidogrel use in patients with intracranial hemorrhage necessitating surgical intervention would lead to a greater risk of death and need for re-operation than those taking other APACs. Methods: Retrospective single institution review was conducted from January, 2010 through November, 2012 for intracranial hemorrhages necessitating surgical evacuation. Acute, subacute and chronic subdural, epidural and intraparenchymal hemorrhages were included. Results: 185 of 410 patients that required surgery for intracranial hemorrhage were on APACs. Overall mortality rate was 33%, with a 37% mortality rate in the APAC group. Overall reoperation rate was 7.5%, and 13% in the APAC group. Chi-square testing demonstrated significance between mortality and clopidogrel use (p = 0.0038), but not in APAC, warfarin or aspirin groups. There was statistical significance between the need for reoperation and APAC use (p = 0.002), aspirin use (p = 0.0097), and clopidogrel use (p = 0.0152), but not warfarin. Multivariate regression demonstrated only clopidogrel use is associated with higher mortality (p = 0.05) and need for reoperation (p = 0.0206). Conclusion: APAC use in the setting of intracranial hemorrhage necessitating surgical evacuation have higher intraoperative blood loss, need for transfusion and risk for adverse cardiac events. Premorbid clopidogrel use is associated with an increased risk in mortality and need for reoperation.

关键词： Antiplatelets Anticoagulation Clopidgrel Mortality Outcomes Reoperation

Pseudotumor cerebri and leukoencephalopathy as the presenting symptom in systemic lupus erythematosus

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Pseudotumor cerebri and leukoencephalopathy as the presentin...

Clinical amelioration of murine lupus by a peptide based on the complementarity determining region-1 of an autoantibody and by cyclophosphamide:similarities and differences in the mechanisms of action

The 8th International Congress on SLE

作者： Ilan Asher Ergas David zev Sthoeger Internal Medicine B Kaplan Medical CenterRechovotIsrael Internal Medicine B Kaplan Medical CenterRechovotIsrael Internal Medicine B Kaplan Medical CenterRechovotIsrael

＜正＞A 41-year-old,previously healthy women,was admitted with general physical and mental deterioration,fatigue and progressive headache for the past three *** examination revealed a butterfly rash over her face,disc...

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Clinical amelioration of murine lupus by a peptide based on ...

A modified protocol for <i>in vitro</i>maturation of mouse oocytes from secondary preantral follicles

The 8th International Congress on SLE

作者： Amir Sharabi zev M Sthoeger Edna Mozes Department of Immunology The Weizmann.Institute of ScienceRehovotIsrael Department of Medicine‘B’ Kaplan HospitalRehovotIsrael Department of Immunology The Weizmann Institute of ScienceRehovotIsrael

＜正＞Purpose:To compare the effects on the clinical manifestations and the mechanism of action of a peptide designated hCDRI（Edratide）and of cyclophosphamide （CYC）in a mouse model of lupus.

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Advances in Bioscience and Biotechnology 2012年第1期3卷 57-74页

作者： Weidong Wang Yaxu Tang Lujuan Ni Theerayut Jongwutiwes Hung-Ching Liu zev Rosenwaks The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine Weill Medical College of Cornell University New York USA

A 2-step culture system was designed and tested for the in vitro maturation efficiency of oocytes from pre-puberty preantral follicles of FVB/N inbred mice. The following modifications were made: 1) The concentration of ITS was reduced by half in the basal MIF medium to minimize uncoordinated growth between oocyte and GC cells;2) Heterogeneous preantral follicles were cultured in groups of 3 - 5 follicles in hanging drops of medium with reduced concentration of ITS for six days to induction follicular aggregation. This hanging drop method mimics a 3-D IVM culture system at the early stage of cultivation in which the sphere structure of each follicle is well maintained. It also enables follicles in each aggregate to communicate with each other, synchronize their growth, and thus prevent immature follicular rupture. 3) Medium was further supplemented with retinoic acid to enhance developmental capacity of meiotically arrested oocytes. After a 14-day culture in vitro, ~37% of the collected inbred preantral follicles completed nuclear maturation. Approximately 94% of the mature oocytes tested were able to be fertilized;and 77% of them developed into healthy embryos. These results demonstrate that our IVM system is reliable to produce a satisfactory number of high quality oocytes. In addition, multiple cytoplasmic parameters, including gene expression of key regulators, chromosome/spindle organization, mitochondrial proliferation and distribution, and total ATP content were explored to characterize the supportive and limiting components of our IVM system so that the culture system can be further optimized.

关键词： Follicle Oocyte In Vitro Maturation In Vitro Fertilization Hanging Drops Fertility Spindle Mitochondrion and ATP Content

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晚期精原细胞瘤治疗观点的改变

国际泌尿系统杂志 1984年第5期04卷 219-220页

作者： zev Wajsman 陆金华

最近复习精原细胞瘤病人的治疗,证实有很高的成功率,临床Ⅰ—Ⅱ期病者的生存率升至97％。然而,发现转移性精原细胞瘤或放疗后复发病者的生存率极低。Ⅲ—Ⅳ期病者若单使用放疗,总的生存率大约为35％。放疗后复发腹部有巨大结节的病人(Ⅱ... 详细信息

最近复习精原细胞瘤病人的治疗,证实有很高的成功率,临床Ⅰ—Ⅱ期病者的生存率升至97％。然而,发现转移性精原细胞瘤或放疗后复发病者的生存率极低。Ⅲ—Ⅳ期病者若单使用放疗,总的生存率大约为35％。放疗后复发腹部有巨大结节的病人(ⅡB期)再用放疗或化疗均不能挽救。该院自1970年至1979年观察到63例经治疗的转移性精原细胞瘤者的生

关键词：精原细胞瘤转移性生存率病者放疗后生殖器肿瘤长春新碱争光霉素搏莱霉素

回应陈忠敏对于《历史比较法和层次分析法》的回应

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语言学论丛 2015年第1期 333-343页

作者：韩哲夫 Department of Asian Languages & Literature University of Washington

为了对使用比较法构拟汉语史进行辩护,尤其是阐明比较法在闽语史中的作用,本文强调两个要点:(1)原始语言"单一性"的含义,(2)罗杰瑞原始闽语构拟的"自然性"(naturalness)。

关键词：历史比较法历史层次分析法原始闽语语言接触

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Semantic Keys and Reading

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宏观语言学 2016年第2期4卷 1-10页

作者： zev bar-Lev San Diego State University USA

Semantic Keys are elements (word-parts) of written language that give an iconic,general representation of the whole word’s meaning. In written Sino-Japanese the “radical”or semantic components play this role. For example, the character meaning 'woman,female’ is the Semantic Key of the character for Ma 'Mama’ (alongside the phonetic component Ma, which means 'horse’ as a separate character). The theory of semantic Keys in both graphic and phonemic aspects is called qTheory or *** most innovative aspect of the present article is the hypothesis that, in languages using alphabetic writing systems, the role of Semantic Key is played by consonants, more specifically the first consonant. Thus, L meaning 'Lif t ’ is the Semantic Key of English L f,Ladle, Lofty, aLps，eLevator，oLympus; Spanish Leva, Lecantarse，aLto，Lengua; Arabic aLLah, and Hebrew? aeL-0aL ‘upto-above’ （the Israeli airline), Polish Lot ‘flight’ （the Polish airline); Hebrew aeL, aeLohim ‘God’， and haLLeluyah ‘praise-ye God’ （using Parallels, 'Lift up God’). Evidence for the universality of the theory is shown by many examples drawn from various languages, including Indo-European Semitic, Chinese and Japanese. The theory reveals hundreds of relationships within and between languages,related and unrelated, that have been “Hiding in Plain Sight”, to mention just one example:the Parallel between Spanish Pan 'bread’ and Mandarin Fan 'rice’.

关键词： Lexicon Semantic Theory Key-letters ambiguity

Characterizing cellular mechanical phenotypes with mechanonode-pore sensing

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Microsystems & Nanoengineering 2018年第1期4卷 438-449页

作者： Junghyun Kim Sewoon Han Andy Lei Masaru Miyano Jessica Bloom Vasudha Srivastava Martha R.Stampfer zev J.Gartner Mark A.LaBarge Lydia L.Sohn Department of Mechanical Engineering University of California at BerkeleyBerkeleyCA 94720-1740USA Department of Bioengineering University of California at BerkeleyBerkeleyCA 94720-1762USA Department of Population Sciences Beckman Research InstituteCity of HopeDuarteCA 91010USA Department of Pharmaceutical Chemistry University of CaliforniaSan FranciscoSan FranciscoCA 94143USA Biological Systems and Engineering Division Lawrence Berkeley National LaboratoryCA 94720USA Graduate Program in Bioengineering University of CaliforniaBerkeleyand University of CaliforniaSan FranciscoBerkeleyCA 94720USA

The mechanical properties of cells change with their differentiation,chronological age,and malignant ***,these properties may be useful label-free biomarkers of various functional or clinically relevant cell ***,we demonstrate mechano-node-pore sensing(mechano-NPS),a multi-parametric single-cell-analysis method that utilizes a four-terminal measurement of the current across a microfluidic channel to quantify simultaneously cell diameter,resistance to compressive deformation,transverse deformation under constant strain,and recovery time after *** define a new parameter,the whole-cell deformability index(wCDI),which provides a quantitative mechanical metric of the resistance to compressive deformation that can be used to discriminate among different cell *** wCDI and the transverse deformation under constant strain show malignant MCF-7 and A549 cell lines are mechanically distinct from non-malignant,MCF-10A and BEAS-2B cell lines,and distinguishes between cells treated or untreated with cytoskeleton-perturbing small *** categorize cell recovery time,ΔT_(r),as instantaneous(ΔTr~0 ms),transient(ΔT_(r)≤40 ms),or prolonged(ΔT_(r)>40 ms),and show that the composition of recovery types,which is a consequence of changes in cytoskeletal organization,correlates with cellular *** the wCDI and cell-recovery time,mechano-NPS discriminates between sub-lineages of normal primary human mammary epithelial cells with accuracy comparable to flow cytometry,but without antibody ***-NPS identifies mechanical phenotypes that distinguishes lineage,chronological age,and stage of malignant progression in human epithelial cells.

关键词： microfluidics mechanical phenotyping node-pore sensing biosensors label-free