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Particuology 2022年第4期20卷 83-94页

作者： Anjun Li Zhenbo wang Liyun Zhu zengli wang Jingyuan Shi Wensan Yang School of New Energy China University of Petroleum(East China)266580 ShandongChina CNPC East China Design Institute Co. Ltd.266071 ShandongChina

A90°elbow equipped with guide vanes was developed with the intent of reducing elbow erosion.Numerical models were formed to predict the maximum erosion rate of elbow and Face-1,and the response surface methodology was used to study the relationship between the erosion rate and structural parameters of guide vane.A second-order response surface model was established to determine the relationship between R and variables,and a reduced cubic(RC)polynomial model was obtained to reveal the relation-ship between R2 and the three factors.The numerical results show that the low-speed region is expended and the maximum discrete particle matter(DPM)concentration is reduced after installing the guide vane.This internal component provides a shelter for the elbow from the direct impact of high-speed solids.

关键词： Elbow Particle erosion Guide vane Response surface methodology

地热能全流发电用两相单螺杆膨胀机理论膨胀过程热力特性研究

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西安交通大学学报 2024年第5期58卷 190-199页

作者：聂涛周宏洋邵华王增丽中国石油大学(华东)新能源学院山东青岛266580

针对地热能发电技术存在的系统效率与热源利用率低的问题,对全流循环发电系统中替代传统汽轮机使用的单螺杆膨胀机进行了热力特性分析。基于质量守恒方程、能量守恒方程与湿蒸汽维里状态方程,建立了考虑液体闪蒸与气液平衡的单螺杆膨胀... 详细信息

针对地热能发电技术存在的系统效率与热源利用率低的问题,对全流循环发电系统中替代传统汽轮机使用的单螺杆膨胀机进行了热力特性分析。基于质量守恒方程、能量守恒方程与湿蒸汽维里状态方程,建立了考虑液体闪蒸与气液平衡的单螺杆膨胀机理论全流膨胀过程的热力学模型,探索了进气温度与干度对气液两相工质状态及膨胀机热力特性的影响机理。结果表明:当进气温度由140℃升高至170℃时,湿蒸汽工质的质量、压力和温度均得到提升,单螺杆膨胀机的输出功率也由210 kW提升至约260 kW,等熵效率在进气温度为160℃时取得77%的最佳值;进气干度的提高会减少进入工作腔湿蒸汽工质质量,进而导致膨胀结束后介质压力与温度的降低,但显著促进了膨胀机的性能参数包括输出功率和等熵效率的提高,当进气干度为0.3时,单螺杆膨胀机的输出功率超过了500 kW,等熵效率也可达76.5%。上述研究结果对应用于地热能全流发电的两相单螺杆膨胀机的热力特性分析与改善以及全流发电技术的优化有一定的参考意义。

关键词：地热能两相湿蒸气单螺杆膨胀机热力特性

DeeplabV3+中引入注意力机制的小面积溢油识别方法

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遥感信息 2024年第2期39卷 95-101页

作者：李翔王增利芮小平邹亚荣河海大学地球科学与工程学院南京211100 自然资源部国家卫星海洋应用中心北京100081 自然资源部空间海洋遥感与应用研究重点实验室北京100081

海面溢油危害大、分布广、时间空间不确定性大,对海洋溢油进行高精度识别与监测对全球生态环境的保护有着重要意义。针对传统卷积神经网络模型对小面积溢油分类不准确的问题,提出一种基于深度学习的SAR影像海上小面积溢油的高精度提取... 详细信息

海面溢油危害大、分布广、时间空间不确定性大,对海洋溢油进行高精度识别与监测对全球生态环境的保护有着重要意义。针对传统卷积神经网络模型对小面积溢油分类不准确的问题,提出一种基于深度学习的SAR影像海上小面积溢油的高精度提取方法。该方法以DeeplabV3+网络模型为基础,引入SE注意力机制来提高网络对海面上小面积溢油的分类精度。基于欧空局开源数据集Oil Spill Detection Dataset建立了海面溢油提取模型,训练得到的平均交并比为77.70%,平均像素精度为98.16%。通过目视对比模型预测图和对比两类精度指标,发现经过注意力机制优化后的DeeplabV3+网络模型明显优于原始网络模型,对小面积溢油监测的效果明显提升。

关键词：海洋溢油深度学习注意力机制 DeeplabV3+ SAR影像

高压混相激光脸浅槽机械密封润滑状态转变特性及密封性能分析

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摩擦学学报（中英文） 2024年第1期44卷 49-59页

作者：刘中琪田静郝木明王增丽任宝杰李小卒张菊华中国石油大学(华东)新能源学院山东青岛266580 东营海森密封技术有限公司山东东营257067

以激光脸浅槽微接触式密封为研究对象,求解考虑混相介质特性和密封端面粗糙度效应的雷诺方程,通过分形接触理论求解微凸体接触力,利用不同微凸体接触状态下求解出的液膜承载系数对混相微接触式机械密封混合润滑状态进行分级,探究了压力... 详细信息

以激光脸浅槽微接触式密封为研究对象,求解考虑混相介质特性和密封端面粗糙度效应的雷诺方程,通过分形接触理论求解微凸体接触力,利用不同微凸体接触状态下求解出的液膜承载系数对混相微接触式机械密封混合润滑状态进行分级,探究了压力及转速等工况条件和开槽形式对密封的润滑状态转变的影响规律.结果表明:混相微接触式机械密封混合润滑状态可分为弹性混合润滑状态、弹塑性混合润滑状态和塑性混合润滑状态3个级别;随着转速升高,液膜承载力不断增大,微凸体接触力逐渐趋向于0,密封环分开实现非接触,此时液膜承载系数为1;压差和槽深越大、混相介质气相容积比越高,矩形槽角度和周期数越小,临界转速越大,润滑状态更稳定,摩擦副分离越困难.

关键词：混相机械密封激光脸浅槽润滑状态临界转速

双螺杆压缩机工作性能测试实验平台搭建及教学应用

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实验技术与管理 2024年第6期41卷 143-150页

作者：王增丽朱澳孙卓辉曲燕中国石油大学(华东)新能源学院山东青岛266580

为提升“过程流体机械”实验教学的高阶性、创新性、挑战度,设计开发了双螺杆压缩机工作性能测试实验平台。该平台可实现工作性能测试、示功(p-V)图绘制等常规实验,并支持开展变工况调节特性分析以及啮合副型面优化设计验证等研究性实... 详细信息

为提升“过程流体机械”实验教学的高阶性、创新性、挑战度,设计开发了双螺杆压缩机工作性能测试实验平台。该平台可实现工作性能测试、示功(p-V)图绘制等常规实验,并支持开展变工况调节特性分析以及啮合副型面优化设计验证等研究性实验。平台硬件部分根据啮合副型面特征设计了传感器布置方案;软件部分基于LabVIEW软件完成在变载工况下绘制p-V图、计算指示功率及分析效率等数据处理功能。该平台应用于实验教学可为培养学生的工程实践创新能力提供保障。

关键词：双螺杆压缩机性能测试开放探索式 LabVIEW 实验平台

Bronchiectasis： still a problem

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Chinese Medical Journal 2014年第1期127卷 157-172页

作者： wang zengli Division of Respiratory and Critical Care Medicine West China HospitalSichuan University Chengdu Sichuan 610041 China

Objective The purpose of this descriptive review was to delineate the current knowledge of bronchiectasis in terms of prevalence,burden of disease,pathophysiology,and management.Data sources The National Library of Medicines MEDLINE and PubMed database （2005-2013） were used to conduct a search using the keyword term ＂bronchiectasis＂.The references for articles being considered for inclusion were searched from additional sources such as conference proceedings.Study selection Criteria for inclusion of articles included data outlining epidemiology,pathogenesis,diagnosis,and evidence-based guidelines for management of bronchiectasis.In assessing the quality of the articles,factors such as size of the population studied,clinical setting of the study,and whether or not the studies were prospective or retrospective were taken into consideration.Review articles were also included in our data collection.Results Despite many advances in modem medicine,bronchiectasis still remains a significant public health problem in developed countries and the developing world.It carries a significant burden worldwide in terms of morbidity and mortality,as well as financially to the affected population.In addition,bronchiectasis may associate with chronic airflow obstruction,regardless of smoking status.Conclusions Bronchiectasis is a debilitating illness responsible for significant morbidity with a poor health-related quality of life.The condition has a substantial socioeconomic cost because both primary and secondary healthcare resources are frequently used and periods of sick leave are common.

关键词： bronchiectasis prevalence burden management

Antimicrobial Mechanism of Saponin from Sapindus mukorossi against Escherichia coli

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Medicinal Plant 2019年第6期10卷 52-55页

作者： Faling LEI Lei XIAO Chunyan YAO zengli wang Infinitus(China)Company Ltd. Xinhui 529156China Zhejiang Academy of Medical Sciences Hangzhou 310013China Healthy Star Bio-Tech R&D Ltd. Shanghai 200335China

[Objectives]To investigate the antimicrobial activity and mechanism for saponin from Sapindus mukorossi against Escherichia coli.[Methods]E.coli was used as the test bacteria,and the antimicrobial effect of Sapindus saponin was studied by the minimum inhibitory concentration method.The antimicrobial mechanism of Sapindus saponin was studied in terms of growth curves,membrane potential,activity of cells,cell surface morphology and cell internal structure.[Results]The results indicate that Sapindus saponin can inhibit the growth of E.coli,the minimum inhibitory concentration is 5 mg/mL and has a significant inhibitory effect on the growth of E.coli.After treated with Sapindus saponin,the membrane potential of E.coli increased by 16.7,17.3 and 19.1 times after exposition to 0.5,1,2 MIC Sapindus saponin respectively.PI staining results show that cell viability decreased and permeability of cell membranes increased.The results of SEM and TEM further corroborate the membrane damage,the cell was damaged after exposition to Sapindus saponin.[Conclusions]The antimicrobial mechanism of Sapindus saponin were to changed membrane potential of cell,and damage the cell membrane structures.

关键词： Sapindus mukorossi Saponin Escherichia coli Antimicrobial mechanism

Medical perspectives of nitric oxide

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CHINESE MEDICAL JOURNAL 1996年第1期109卷 60-2页

作者： wang zengli DivisionofPulmonaryDiseases DepartmentofMedicine WestChinaUniversityofMedicalSciences Chengdu

Long-term in vivo chimeric cells tracking in non-human primate

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Protein & Cell 2024年第3期15卷 207-222页

作者： Junmo Wu Yu Kang Xiang Luo Shaoxing Dai Yuxi Shi Zhuoyao Li zengli Tang Zhenzhen Chen Ran Zhu Pengpeng Yang Zifan Li Hong wang Xinglong Chen Ziyi Zhao Weizhi ji Yuyu Niu State Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming 650500China Yunnan Key Laboratory of Primate Biomedical Research Kunming 650500China Faculty of Life Science and Technology Kunming University of Science and TechnologyKunming 650500China

Non-human primates(NHPs)are increasingly used in preclinical trials to test the safety and efficacy of biotech-nology therapies.Nonetheless,given the ethical issues and costs associated with this model,it would be highly advantageous to use NHP cellular models in clinical studies.However,developing and maintaining the naive state of primate pluripotent stem cells(PSCs)remains difficult as does in vivo detection of PSCs,thus limiting biotech-nology application in the cynomolgus monkey.Here,we report a chemically defined,xeno-free culture system for culturing and deriving monkey PSCs in vitro.The cells display global gene expression and genome-wide hypometh-ylation patterns distinct from monkey-primed cells.We also found expression of signaling pathways components that may increase the potential for chimera formation.Crucially for biomedical applications,we were also able to integrate bioluminescent reporter genes into monkey PsCs and track them in chimeric embryos in vivo and in vitro.The engineered cells retained embryonic and extra-embryonic developmental potential.Meanwhile,we generated a chimeric monkey carrying bioluminescent cells,which were able to track chimeric cells for more than 2 years in living animals.Our study could have broad utility in primate stem cell engineering and in utilizing chimeric monkey models forclinical studies.

关键词： pluripotent stem cells bioluminescence imaging non-human primates

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考虑甲烷溶解效应的液膜密封稳态性能研究

摩擦学学报 2023年第6期43卷 645-656页

作者：王青阳厉晓英王增丽于博郝木明中国石油大学(华东)新能源学院山东青岛266580

针对油气混输工况密封腔内含气率变化所引起的液膜承载力不稳定问题,考虑密封腔内油气两相介质的互溶性特征,将溶解度方程引入包含Jakobsson-Floberg-Olsson(JFO)边界条件的广义稳态Reynolds方程,建立了考虑甲烷溶解效应的液膜密封润滑... 详细信息

针对油气混输工况密封腔内含气率变化所引起的液膜承载力不稳定问题,考虑密封腔内油气两相介质的互溶性特征,将溶解度方程引入包含Jakobsson-Floberg-Olsson(JFO)边界条件的广义稳态Reynolds方程,建立了考虑甲烷溶解效应的液膜密封润滑模型.采用有限差分法求解该溶解润滑模型,研究了液膜压力、甲烷溶解度及油相黏度之间的相互影响机制.在不同的螺旋槽结构参数与工况条件下,对比分析了甲烷溶解效应对液膜密封机理及密封性能的影响.结果表明:甲烷溶解效应在液膜高压区对油相黏度影响大;考虑甲烷溶解时所得的液膜开启力减小、空化率增大、摩擦系数增大以及泄漏量减小,且液膜动压效应越强时甲烷溶解效应对密封性能的影响越大.在高压及输送油气介质时,气体溶解对密封性能的影响不可忽略.

关键词：螺旋槽液膜密封甲烷溶解有限差分法空化密封性能