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Different patterns of association between white matter microstructure and plasma unsaturated fatty acids in those with high risk for psychosis and healthy participants

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General Psychiatry 2022年第2期35卷 109-118页

作者： Wenjun Su Zhixing Li Lihua Xu Jiahui zeng yingying Tang Xiaochen Tang Yanyan Wei Qian Guo Tianhong Zhang Jijun Wang Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Heaith Center Shanghai Jiao Tong University School of MedicineShanghaiChina CAS Center for Excellence in Brain Science and Intelligence Technology(CEBSIT) Chinese Academy of ScienceShanghaiChina Institute of Psychology and Behavioral Science Shanghai Jiao Tong UniversityShanghaiChina

Background Disrupted white matter(WM)microstructure has been commonly identified in youth at clinical high risk(CHR)for *** lines of evidence suggest that fatty acids,especially unsaturated fatty acids(UFAs),might play a crucial role in the WM pathology of early onset ***,evidence linking UFA and WM microstructure in CHR is quite *** We investigated the relationship between the plasma UFA level and WM microstructure in CHR participants and healthy controls(HC).Methods Plasma fatty acids were assessed and diffusion tensor imaging(DTI)data were performed with tract-based spatial statistics(TBSS)analysis for 66 individuals at CHR for psychosis and 70 *** Both the global and regional diffusion measures showed significant between-group differences,with decreased fractional anisotropy(FA)but increased mean diffusivity(MD)and radial diffusivity(RD)found in the CHR group compared with the HC *** top of that,we found that in the HC group,plasma arachidic acid showed obvious trend-level associations with higher global FA,lower global MD and lower global RD,which regionally spread over the corpus callosum,right anterior and superior corona radiata,bilateral anterior and posterior limb of the internal capsule,and bilateral superior longitudinal ***,there were no associations between global WM measures and any UFA in the CHR ***,we even found negative associations between arachidic acid levels and regional FA values in the right superior longitudinal fasciculus and right retrolenticular part of the internal capsule in the CHR *** Compared with the HC group,CHR subjects exhibited a different pattern of association between WM microstructure and plasma UFA,with a neuroprotective effect found in the HC group but not in the CHR *** discrepancy could be due to the excessively upregulated UFAs accumulated in the plasma of the CHR group,highlighting the role of balanced plasma-membrane fatty

关键词： unsaturated diffusion linking

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短肢剪力墙节点推覆力模拟分析

湖南工业大学学报 2018年第1期32卷 22-28页

作者：曾萤萤杨晓华蒋国维李小岗湖南工业大学土木工程学院湖南株洲412007

通过改变短肢剪力墙节点模型的轴压比,利用ANSYS软件对其节点做推覆力分析。通过5组(轴压比分别为:0.1,0.2,0.3,0.4,0.5)节点模拟实验,对比分析各轴压比下节点的耗能性能、刚度退化、裂缝的发展、极限承载力、极限承载力下对应的极限位... 详细信息

通过改变短肢剪力墙节点模型的轴压比,利用ANSYS软件对其节点做推覆力分析。通过5组(轴压比分别为:0.1,0.2,0.3,0.4,0.5)节点模拟实验,对比分析各轴压比下节点的耗能性能、刚度退化、裂缝的发展、极限承载力、极限承载力下对应的极限位移、延性等的变化规律。研究结果表明:反向加载时裂缝的发展速度远大于正向加载时裂缝的发展速度;连梁与墙肢交接处为其薄弱环节;轴压比在0.3左右时节点的耗能性质最优,极限承载力、极限位移最大,抗震性能最好。

关键词：短肢剪力墙裂缝轴压比

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短肢剪力墙节点扭转性能的有限元分析

湖南工业大学学报 2018年第2期32卷 1-7页

作者：蒋国维杨晓华曾莹莹李小岗湖南工业大学土木工程学院湖南株洲412007

由于混凝土塑性变形的影响,短肢剪力墙节点在受到扭转作用加剧时,与按弹性理论计算的结果相差较大。因此,利用ANSYS有限元计算软件,模拟在水平低周反复荷载作用下的T型短肢剪力墙节点,通过分析其结构变形、裂缝和混凝土应力情况等研究... 详细信息

由于混凝土塑性变形的影响,短肢剪力墙节点在受到扭转作用加剧时,与按弹性理论计算的结果相差较大。因此,利用ANSYS有限元计算软件,模拟在水平低周反复荷载作用下的T型短肢剪力墙节点,通过分析其结构变形、裂缝和混凝土应力情况等研究节点的扭转性能。研究结果表明:在梁端施加水平作用力可以对节点造成扭转破坏,且梁与墙连接处因出现应力集中而最先出现裂缝,裂缝出现后因部分混凝土退出工作,节点的受力性能发生质的改变;在一定范围内,适当增加轴压比可以提高短肢剪力墙节点的耗能能力,增加其延性;对于容易受到扭转作用的短肢剪力墙节点,可以适当加强节点配筋布置以承受全部的外扭作用,避免节点被过早破坏。

关键词：短肢剪力墙节点有限元分析扭转

竖向低周反复荷载作用下短肢剪力墙节点滞回性能的有限元分析

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湖南工业大学学报 2018年第3期32卷 30-36页

作者：李小岗杨晓华曾莹莹蒋国维湖南工业大学土木工程学院湖南株洲412007

利用ANSYS软件建立有限元模型,分析短肢剪力墙节点在竖向低周反复荷载作用下的耗能特性。根据所建立的有限元模型,得到结构模型在不同轴压比下的梁端荷载-位移滞回曲线和骨架曲线。研究结果表明:在一定范围内增大轴压比能提高节点的耗... 详细信息

利用ANSYS软件建立有限元模型,分析短肢剪力墙节点在竖向低周反复荷载作用下的耗能特性。根据所建立的有限元模型,得到结构模型在不同轴压比下的梁端荷载-位移滞回曲线和骨架曲线。研究结果表明:在一定范围内增大轴压比能提高节点的耗能能力。

关键词：短肢剪力墙节点轴压比滞回曲线骨架曲线耗能性能

A hippocampal anti-hypertensive mechanism induced by twirling reinforcing-reducing manipulation in rats

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Journal of Traditional Chinese Medical Sciences 2023年第1期10卷 106-117页

作者： Jiao Sun Liu Yan Yunhong Zhu Jingrong Liang yingying Zang Tianxiao zeng Xiaomin Hao Pui Yee Wong Qingguo Liu School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese MedicineBeijing 102488China Department of Rehabilitation Qingdao Hospital of Traditional Chinese Medicine(Qingdao Hiser Hospital)Qingdao 266033China Department of Acupuncture Mediseed Chinese Medicine Consulting CentrePetaling Jaya 46200Malaysia

Objective:To investigate a hippocampal anti-hypertensive mechanism induced by twirling reinforcingreducing manipulation(TRRM)using proteomics in ***:Forty-two male spontaneously hypertensive rats were randomly divided into 3 groups,and 14 Wistar-Kyoto rats were served as control *** the twirling reinforcing(TRF)group,needles were directly inserted into the Taichong(LR 3)point,then thumbs were moved heavily forward and lightly backward for 3 min,while needles remained inserted for 17 *** the twirling reduction(TRD)group,the same treatment was applied as in the TRF group except that the thumb moved lightly forward and heavily *** the model and control groups,only the corresponding grasping and fixation were *** interventions were conducted for 14 *** blood pressure(BP)of all rats was measured one day before intervention and every other day *** hematoxylin-eosin(H&E)staining,label-free and parallel reaction monitoring proteomic techniques were used to assess hippocampal samples from each ***:Systolic BPs showed a significant decrease in the TRF and TRD groups compared with the model group(P<.01).In the model group,H&E staining showed obvious pathological changes in the hippocampus,while in the TRF and TRD groups,the hippocampal morphology was only slightly *** proteomic analysis revealed 1163 differential protein expressions between *** Ontology enrichment analysis confirmed that the differentially expressed proteins were enriched in different biological processes,cellular components,and molecular *** Encyclopedia of Genes and Genomes enrichment analysis showed that TRRM proteins were expressed in the serotonergic synapse pathway,renin-angiotensin system,the mitogen-activated protein kinase signaling pathway,and the peroxisome pathway,which were all also related to BP ***:TRRM can significantly lower the BP of *** mode of action may be through the activation

关键词： Twirling reinforcing-reducing method Blood pressure Hypertension Hippocampus Proteomics Spontaneously hypertension rats Taichong Acupuncture

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不同改良方式对豆禾混播草地AMF的影响

四川农业大学学报 2024年第2期42卷 364-370页

作者：孙雨豪李旭旭曾园石雨鑫弓晋超苏颖颖冯恣萱贾雨圻陈延涛周冀琼四川农业大学草业科技学院成都611130

【目的】探究不同改良方式对豆禾混播草地的丛枝菌根真菌(arbuscular mycorrhizal fungi,AMF)群落及区系特征的影响机制。【方法】以云南省种羊场豆禾混播草地为研究对象,调查2019年直接改良(DR)草地与轮作改良(CR)草地,以围封(NG)草地... 详细信息

【目的】探究不同改良方式对豆禾混播草地的丛枝菌根真菌(arbuscular mycorrhizal fungi,AMF)群落及区系特征的影响机制。【方法】以云南省种羊场豆禾混播草地为研究对象,调查2019年直接改良(DR)草地与轮作改良(CR)草地,以围封(NG)草地为对照,借助高通量测序、菌丝测定与孢子密度测定技术,测定AMF群落特征。【结果】直接改良草地中孢子密度、球囊霉属(Glomus)显著高于轮作改良方式。孢子密度与土壤硝态氮、土壤微生物氮含量呈显著正相关关系,菌丝长度、菌丝密度与土壤氨态氮含量呈极显著正相关关系,与土壤速效磷含量呈极显著负相关关系。【结论】直接改良方式比轮作改良方式更有利于土壤养分的增加,更有利于AMF与植物共生关系的构建。

关键词：丛枝菌根真菌豆禾混播轮作草地恢复

N-Heterocyclic Carbene Copper(Ⅰ)Complex Catalyzed Coupling of(Hetero)aryl Chlorides and Nitrogen Heterocycles:Highly Efficient Catalytic System

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Chinese Journal of Chemistry 2020年第11期38卷 1252-1256页

作者： Mengyao Zhang yingying Zhang Huixin Zhang Yongfei zeng Guiyan Liu Tianjin Key Laboratory of Structure and Performance for Functional Molecules Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry(Tianjin Normal University)Ministry of EducationCollege of ChemistryTianjin Normal UniversityTianjin 300387China

of main observation and conclusion A highly efficient catalytic system for the N-arylation reactions of(hetero)aryl chlorides and nitrogen heterocycles with a copper(l)complex containing a 1,10-phenanthroline analogue N-heterocyclic carbene(NHC)has been *** complex was characterized by^lH NMR and^13C NMR spectroscopy and elemental analysis,and its structure was determined by single-crystal X-ray *** NHC-copper(l)complex was employed as pre-catalyst for Ullmann type N-arylation reactions of(hetero)aryl chlorides with various azoles.A variety of hindered and functionalized azoles and(hetero)aryl chlorides were transformed in good to excellent yields.

关键词： diffraction. copper Catalytic

国审高蛋白大豆品种泉豆17的选育及高产稳产特性

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中国种业 2024年第1期 122-125页

作者：吕美琴李明松林文磊康蓉蓉曾红英施迎迎王智卿福建省泉州市农业科学研究所泉州362212 福建省泉州市农业农村局种子站泉州362000

泉豆17是以浙9703为母本、南春201为父本进行有性杂交,经系谱法选育而成的春大豆新品种,2016-2017年参加国家热带亚热带地区春大豆组区域试验,2年每667m^(2)平均产量为155.2kg;2018年参加国家热带亚热带地区春大豆组生产试验,平均产量为... 详细信息

泉豆17是以浙9703为母本、南春201为父本进行有性杂交,经系谱法选育而成的春大豆新品种,2016-2017年参加国家热带亚热带地区春大豆组区域试验,2年每667m^(2)平均产量为155.2kg;2018年参加国家热带亚热带地区春大豆组生产试验,平均产量为147.1kg。泉豆17粗蛋白质含量46.15%,粗脂肪含量18.56%,蛋白含量脂肪含量之和为64.71%,为高蛋白质品种。2020年通过福建省农作物品种审定委员会审定(闽审豆20200001),2021年通过国家农作物品种审定委员会审定(国审豆20210078),适合在福建省、广东省、广西自治区、海南省、江西省南部、湖南省南部春播种植。

关键词：大豆泉豆17 高蛋白选育高产稳产

Responses of soil nematode community to monoculture or mixed culture of a grass and a legume forage species in China

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Pedosphere 2020年第6期30卷 791-800页

作者： yingying YE Yichao RUI Zhaoxia zeng Xunyang HE Kelin WANG Jie ZHAO Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125China Huanjiang Observation and Research Station for Karst Ecosystems Chinese Academy of SciencesHuanjiang 547100China Department of Soil Science University of Wisconsin-MadisonMadison WI 53705USA University of Chinese Academy of Sciences Beijing 100049China

Mixed cultivation of fast-growing grasses and nitrogen(N)-fixing legumes for forage production is widely considered effective for obtaining sustained high forage yields without depleting soil N ***,the effects of monoculture and mixed culture of these species on soil food webs are poorly *** this study,soil nematode communities were examined as indicators of the soil food web structure of monoculture and mixed culture of grass and legume at three N levels,i.e.,338(low),450(moderate),and 675(high)kg N ha-1 year-1,across 2 years in wet and dry seasons,using the grass Paspalum wetsfeteini and the legume Medicago sativa(alfalfa),both commonly cultivated ***-measures analysis of covariance showed that compared with grass monoculture,legume monoculture and grass-legume mixture increased abundances of herbivorous,bacterivorous,and fungivorous nematodes in the soil food web under the low and moderate N fertilization *** response curve results showed that the abundance of Helicotylenchus,a plant parasite,was significantly higher under legume monoculture than other planting systems at the low N fertilization *** equation model analysis indicated that the legume increased bacterivore abundance,while increasing N fertilization decreased omnivore *** legume might increase the quantity and quality of food resources for soil biota,resulting in the bottom-up control of soil nematode *** results indicate that targeted control of a soilborne pathogen,Helicotylenchus,is required in alfalfa-based planting *** addition,high inorganic N application,which is detrimental to legume-rhizobia symbiosis,nullified the otherwise positive effects of legumes on soil nematodes.

关键词： bacterivore bottom-up control fertilization fungivore herbivore nitrogen soil food web soilborne pathogen