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Acta Geologica Sinica(English Edition) 2024年第4期98卷 1051-1063页

作者： CUI Fengzhen LIU-zeng jing LI Yunshuai XU Qiang TANG Maoyun WANG Heng SUN Zhaotong School of Earth System Science Tianjin UniversityTianjin 300072China State Key Laboratory of Earthquake Dynamics Institute of GeologyChina Earthquake AdministrationBeijing 100029China School of Earth Science and Technology Southwest Petroleum UniversityChengdu 610500China Chongqing Earthquake Agency Chongqing 401147China

The reconstruction of paleo-elevation serves a dual purpose to enhance our comprehension of geodynamic processes affecting terrestrial landforms and to contribute significantly to the interpretation of atmospheric circulation and *** oxygen(δ~(18)O_w)and deuterium(δD_w)isotopes in atmospheric precipitation are systematically depleted with the increase of altitude,which are typical and widely applicated *** utilization of hydrogen isotope of hydrous silicate minerals within the shear zone system,volcanic glass,and plant leaf wax alkanes offers valuable insights for addressing evaporation and *** this paper,we review the principle,application conditions,and influencing factors of the hydrogen isotope *** addition,we discuss the feasibility of utilizing this technique for quantitatively estimating the paleo-elevation of the southeastern Tibetan Plateau,where multiple shear zones extend over hundred kilometers parallel to the topographic gradient.

关键词： paleo-elevation hydrogen isotope hydrous silicate minerals volcanic glass Tibetan Plateau

Inhibiting MMP13 Attenuates Deep Vein Thrombosis in a Mouse Model by Reducing the Expression of Pdpn

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Current Medical Science 2024年第2期44卷 369-379页

作者： Ji LUO Jin ZHOU jing-zeng LUO Hai-long WANG Xue-ling ZHAO Ru-dan ZHOU Department of Intensive Care Unit The First People's Hospital of ZiyangZiyang 641300China Department of Orthopedics Kunming Medical University Second Affiliated HospitalKunming 650033China Department of Orthopedics Kunming Medical University First Affiliated HospitalKunming 650032China Department of Orthopedics The Third People's Hospital of Yunnan ProvinceKunming 650200China

Objective:Matrix metalloproteinase 13(MMP13)is an extracellular matrix protease that affects the progression of atherosclerotic plaques and arterial thrombi by degrading collagens,modifying protein structures and regulating inflammatory responses,but its role in deep vein thrombosis(DVT)has not been *** purpose of this study was to investigate the potential effects of MMP13 and MMP13-related genes on the formation of ***:We altered the expression level of MMP13 in vivo and conducted a transcriptome study to examine the expression and relationship between MMP13 and MMP13-related genes in a mouse model of *** screening genes possibly related to MMP13 in DVT mice,the expression levels of candidate genes in human umbilical vein endothelial cells(HUVECs)and the venous wall were *** effect of MMP13 on platelet aggregation in HUVECs was investigated in ***:Among the differentially expressed genes,interleukin 1 beta,podoplanin(Pdpn),and factor VIII von Willebrand factor(F8VWF)were selected for analysis in *** MMP13 was inhibited,the expression level of PDPN decreased significantly in *** HUVECs,overexpression of MMP13 led to an increase in the expression level of PDPN and induced platelet aggregation,while transfection of PDPN-siRNA weakened the ability of MMP13 to increase platelet ***:Inhibiting the expression of MMP13 could reduce the burden of DVT in *** mechanism involves downregulating the expression of Pdpn through MMP13,which could provide a novel gene target for DVT diagnosis and treatment.

关键词： deep vein thrombosis matrix metalloproteinase 13 podoplanin

Activation of autophagy by Citri Reticulatae Semen extract ameliorates amyloid-beta-induced cell death and cognition deficits in Alzheimer’s disease

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Neural Regeneration Research 2024年第11期19卷 2467-2479页

作者： Yong Tang jing Wei Xiao-Fang Wang Tao Long Xiaohong Xiang Liqun Qu Xingxia Wang Chonglin Yu Xingli Xiao Xueyuan Hu jing zeng Qin Xu Anguo Wu Jianming Wu Dalian Qin Xiaogang Zhou Betty Yuen-Kwan Law Dr.Neher’s Biophysics Laboratory for Innovative Drug Discovery State Key Laboratory of Quality Research in Chinese MedicineMacao University of Science and TechnologyMacao Special Administrative RegionChina Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica Southwest Medical UniversityLuzhouSichuan ProvinceChina Eye School and Key Laboratory of Sichuan Province Ophthalmopathy Prevention&Cure and Visual Function Protection of Chengdu University of TCM ChengduSichuan ProvinceChina School of Basic Medical Sciences Southwest Medical UniversityLuzhouSichuan ProvinceChina Department of Ophthalmology The Affiliated Hospital of Southwest Medical UniversityLuzhouSichuan ProvinceChina Department of Neurology The First People’s Hospital of NeijiangNeijiangSichuan ProvinceChina

Amyloid-beta-induced neuronal cell death contributes to cognitive decline in Alzheimer’s *** Reticulatae Semen has diverse beneficial effects on neurodegenerative diseases,including Parkinson’s and Huntington’s diseases,however,the effect of Citri Reticulatae Semen on Alzheimer’s disease remains *** the current study,the anti-apoptotic and autophagic roles of Citri Reticulatae Semen extract on amyloid-beta-induced apoptosis in PC12 cells were first *** Reticulatae Semen extract protected PC12 cells from amyloid-beta-induced apoptosis by attenuating the Bax/Bcl-2 ratio via activation of *** addition,Citri Reticulatae Semen extract was confirmed to bind amyloid-beta as revealed by biolayer interferometry in vitro,and suppress amyloid-beta-induced pathology such as paralysis,in a transgenic Caenorhabditis elegans in vivo ***,genetically defective Caenorhabditis elegans further confirmed that the neuroprotective effect of Citri Reticulatae Semen extract was *** importantly,Citri Reticulatae Semen extract was confirmed to improve cognitive impairment,neuronal injury and amyloid-beta burden in 3×Tg Alzheimer’s disease *** revealed by both in vitro and in vivo models,these results suggest that Citri Reticulatae Semen extract is a potential natural therapeutic agent for Alzheimer’s disease via its neuroprotective autophagic effects.

关键词： Alzheimer’s disease amyloid-beta apoptosis autophagy Caenorhabditis elegans Citri Reticulatae Semen

Coupling N-doping and confined Co_(3)O_(4) on carbon nanotubes by polydopamine coating strategy for pleiotropic water purification

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Rare Metals 2024年第7期43卷 3146-3160页

作者： Wen-Long Tu Gang Wang Yue Zhang Hong-Yang Zhu Rong-Rong Du Hong-Yao Zhao Sheng Tang zeng-jing Guo Jun Yang Fu Yang Cheng-Zhang Zhu School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Chemistry and Chemical Engineering Liaocheng UniversityLiaocheng 252000China School of Material Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Environmental Science and Engineering Nanjing Tech UniversityNanjing 211816China

The development of effective and sustainable solutions for pleiotropic water purification becomes urgent and *** Fenton-like catalysts for activation of peroxymonosulfate(PMS)to purify organic wastewater show great *** this work,by tuning metal loading with an in-situ polydopamine coating strategy,oxygen vacancy-enriched Co_(3)O_(4) loading on N-doped carbon nanotubes(CNTs)were constructed to enhance PMS activation efficiency for pollutants ***,the obtained modified CNTs afford a well-developed N-containing network structure,which is further endowed with abundant Co(Ⅱ)/Co(Ⅲ)redox cycles and significant metal-carbon *** particular,the surface N doping in CNTs might induce the oriented enrichment of pollutants around the catalyst,which reduces the migration distance and correspondingly improves the utilization of reactive oxidative *** electron transfer efficiency of the catalyst can be further improved by incorporating oxygen vacancy-enriched Co_(3)O_(4).The performance results show that the optimal NC/Co-1 could mineralize 20×10^(-6)of bisphenol A(BPA)by almost 98%in 8 min.A low reaction activation energy(26.05 kJ·mol^(-1))in BPA degradation was demonstrated by the NC/*** importantly,NC/Co-1 can inherit excellent degradation performance towards oxytetracycline,2,4-dichlorophenol,and tetracycline,showing wide practical *** addition,by virtue of the photothermal conversion property,NC/Co-1 achieves an additive function for interfacial solar water evaporation(1.84 kg·m^(-2)·h^(-1),112.51%),showing impressive potential for clean water recovery under complicated environmental pollution conditions.

关键词： Carbon nanotube Advanced oxidation process Co_(3)O_(4) Photothermal conversion Solar water evaporation

Constructing core@shell structured photothermal nanosphere with thin carbon layer confined Co-Mn bimetals for pollutant degradation and solar interfacial water evaporation

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Rare Metals 2024年第4期43卷 1686-1701页

作者： Hong-Yang Zhu Meng-Ting Liu Gang Wang Rong-Rong Du Hong-Yao Zhao Hao Lu Shi-Qi Yang Sheng Tang zeng-jing Guo Jun Yang Cheng-Zhang Zhu Fu Yang School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang212003China School of Chemistry and Chemical Engineering Liaocheng UniversityLiaocheng252000China School of Material Science and Engineering Jiangsu University of Science and TechnologyZhenjiang212003China School of Environmental Science and Engineering Nanjing Tech UniversityNanjing210009China

Photothermal material applied in environmental governance has attracted growing *** combining the Stober method and dopamine-triggered coating strategy,Co-Mn precursor was in situ incorporated into the poly dopamine(PDA)layer over the surface of silica ***,a unique photothermal nanosphere with SiO_(2)core and thin carbon layer and dual Co-Mn oxides shell was allowed to form by sequential heat treatment in the inert atmosphere(SiO_(2)@CoMn/C).The bimetallic fraction of Co/Mn in the carbon layer and post-treatment calcination temperature was comprehensively tuned to optimize the peroxymonosulfate(PMS)activation performance of the *** state of bimetallic species was studied including their physical distribution,chemical valence,and interplay by various ***,Co oxides appear as dominant monodispersed nanoparticles(~10 nm),while Mn with cluster-like morphology is observed to uniformly distribute over thin-layer carbon and adhered to the surface of SiO_(2)nanospheres(~250 nm).The calcined temperature could tune the oxidized state of Co species,leading to the optimization of the catalytic performance of introduced dual metal *** a result,this obtained optimal catalyst integrated the advantages of exposed bimetallic CoMn species and N-doped thin carbon to deliver excellent catalytic PMS activation performance and photothermal synergetic catalytic mineralization ability for diversiform *** reactions condition controls and anion interference studies were conducted to identify the adaptability of the optimal ***,the application of solar-driven interfacial water evaporation using optimal SiO_(2)@Co_3Mn_1/C-600 catalyst was explored,showing a high water evaporation rate of 1.48 kg·m^(-2)·h^(-1)and an efficiency of 95.2%,further revealing a comprehensive governance functionality of obtained material in the complex pollution condition.

关键词： Photothermal Peroxymonosulfate(PMS)activation Bimetallic synergy Water evaporation Advanced oxidation process

Heterostructure:application of absorption-catalytic center in lithium-sulfur batteries

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Rare Metals 2024年第4期43卷 1461-1487页

作者： Fei Wang Chun-Man Yang Yong-Qi Wang Dan You Wen-Hao Yang Rong-Wei Huang Ji-Yue Hou Qian Wang Ying-Jie Zhang Ying Wang Yue-jing zeng Yi-Yong Zhang Xue Li National Local Joint Engineering Research Center for Lithium-Ion Batteries and Materials Preparation Technology Key Laboratory of Advanced Batteries Materials of Yunnan ProvinceFaculty of Metallurgical and Energy EngineeringKunming University of Science and TechnologyKunming650093China College of Electrical Information Engineering Panzhihua UniversityPanzhihua617000China State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Centre of Chemistry for Energy MaterialsState-Province Joint Engineering Laboratory of Power Source Technology for New Energy VehicleEngineering Research Center of Electrochemical TechnologyMinistry of EducationCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen361005China

Due to the high theoretical specific capacity(1675 mAh·g^(-1)),low cost,and high safety of the sulfur cathodes,they are expected to be one of the most promising rivals for a new generation of energy storage ***,the shuttle effect,low conductivity of sulfur and its discharge products,volume expansion,and other factors hinder the commercialization of lithium-sulfur batteries(LSBs).The development of sulfur-fixing materials and the design of multifunctional materials to enhance the electrochemical performance of LSBs have been the main research priorities in recent *** of the advantages of high conductivity,built-in electric field,and good synergism,more and more researchers have employed heterostructure into sulfur-fixing materials to enhance the catalytic and absorption ability for *** this review,the principle of heterostructure and the mechanism of enhancing the performance of lithium-sulfur batteries are *** applications of heterostructure in cathode and interlayer of LSBs in the latest years are ***,the cutting-edge troubles and possibilities of heterostructures in LSBs are briefly presented.

关键词： Lithium-sulfur batteries(LSBs) Heterostructure Built-in electric field Catalytic Absorption

Association of Hypertension and Plant-based Dietary Patterns on Cognitive Impairment: A Nationwide Cohort Study in China

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Food Science and Human Wellness 2024年

作者： Fang Liang Jialin Fu Gabrielle Turner-McGrievy Yechuang Wang Kai Ding jing zeng Justin B Moore Rui Li Chengdu High-tech Zone Center for Diseases Control and Prevention School of Public Health， Wuhan University Department of Implementation Science， Division of Public Health Sciences， Wake Forest School of Medicine Department of Health Promotion， Education， and Behavior Arnold School of Public Health， University of South Carolina Columbia， SC USA School of Nursing， Wuhan University

This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet (PBD) patterns may modify the association. We analyzed 4485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longevity Survey (2011-2018). Cognitive function was assessed by the Mini-mental State Examination (MMSE)， and cognitive impairment was defined as an MMSE score below 18 points. Diet patterns were assessed using the overall plant-based diet index (PDI)， healthful plant-based diet index (hPDI)， and unhealthful plant-based diet index (uPDI) derived from a simplified food frequency questionnaire (FFQ). Blood pressure was measured through physical examination. Cox proportional hazard regression and restricted cubic spline were performed. Participants with hypertension had an increased risk of cognitive impairment compared with normal group. The associations between hypertension and cognitive impairment were more pronounced among participants with lower PDI than those with higher PDI， among participants with lower hPDI than those with higher hPDI， and among participants with higher uPDI than those with lower uPDI. A healthful PBD pattern may attenuate hypertension-induced cognitive impairment， while an unhealthful PBD pattern may exacerbate hypertension-induced cognitive impairment in elderly. Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population.

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“技术—组织—环境”因素联动对互联网企业数字创新的影响--基于TOE框架的模糊集定性比较分析与必要条件分析

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科学学与科学技术管理 2024年第3期45卷 21-40页

作者：张铭曾静曾娜王冬玲三峡大学经济与管理学院湖北宜昌443002

数字创新作为数字经济的源头活水,已成为催生新动能和促进经济高质量发展的重要战略工具。如何优化企业数字创新机制及提高数字创新水平是有待解决的重要问题。但以往研究多强调单一前因对数字创新的“净效应”,较少以整体框架探究技术... 详细信息

数字创新作为数字经济的源头活水,已成为催生新动能和促进经济高质量发展的重要战略工具。如何优化企业数字创新机制及提高数字创新水平是有待解决的重要问题。但以往研究多强调单一前因对数字创新的“净效应”,较少以整体框架探究技术、组织与环境因素影响数字创新的复杂因果机制,一定程度上忽视了不同前因间的联合效应。为进一步探索数字创新的影响机制,促进数字创新实践,以互联网企业为研究对象,选取沪深A股上市的20家互联网企业为案例样本,基于TOE框架,采用模糊集定性比较分析与必要条件分析方法,探寻技术、组织与环境三个层面五个前因条件对互联网企业数字创新的影响。研究发现:(1)单个前因条件不构成引致高水平数字创新的必要条件;(2)存在4条产生高水平数字创新的组态,可归为技术与环境协同的大数据能力赋能型(H1)、技术与环境协同的创新能力支持型(H2a)、技术与环境协同的大数据能力与创新能力联合支持型(H2b)、吸收能力与数字化情境双轮驱动型(H3);(3)存在4条产生非高水平数字创新的组态,且与高水平数字创新组态存在非对称关系。

关键词：数字创新互联网企业 TOE框架模糊集定性比较分析必要条件分析

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资源枯竭城市转型扶助政策与税收可持续能力

税收经济研究 2024年第1期29卷 34-45页

作者：杨得前曾静集美大学地方财政绩效研究中心集美大学财经学院

税收可持续性是税收发挥其在国家治理中基础性、支柱性和保障性作用的重要基础。资源枯竭型城市转型在推动经济社会高质量发展、促进税收可持续能力有效提升等方面被寄予厚望。文章以资源枯竭城市转型扶助政策作为准自然实验,基于新发... 详细信息

税收可持续性是税收发挥其在国家治理中基础性、支柱性和保障性作用的重要基础。资源枯竭型城市转型在推动经济社会高质量发展、促进税收可持续能力有效提升等方面被寄予厚望。文章以资源枯竭城市转型扶助政策作为准自然实验,基于新发展理念构建税收可持续能力度量体系,并采用多时点DID考察了资源枯竭型城市转型对税收可持续能力的影响。结果表明:(1)资源枯竭城市转型扶助政策显著推动了地区税收可持续能力的提升;(2)机制分析表明,扶助政策主要通过优化地区产业结构、缩小地区间居民收入差异两条渠道促进税收可持续能力的提升;(3)政策效果会因城市地理区位、资源类别、税收征管强度的不同而产生显著差异性。基于上述发现,应进一步调整产业结构、利用城市区位优势、发挥市场作用以及优化税收征管,推动资源枯竭型城市转型,进而更加高效地促进税收可持续增长。

关键词：资源枯竭型城市税收可持续能力新发展理念城市转型

Incidence rate and risk factors of second primary neoplasms among older patients with hematological malignancies:Insights from a Chinese single-center experience(1997-2021)

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Cancer Pathogenesis and Therapy 2024年第4期2卷 285-291页

作者： Yadi Zhong Bing Zhai jing zeng Bo Yang Bo Guo Xuechun Lu Department of Hematology The Second Medical Center&National Clinical Research Center for Geriatric DiseasesChinese PLA General HospitalBeijing 100853China Department of Endocrinology The Second Medical Center&National Clinical Research Center for Geriatric DiseasesChinese PLA General HospitalBeijing 100853China

Background:Patients with hematological malignancies face an increased risk of developing second primary neoplasms due to various factors,including immune system compromise and chemotherapy-related ***,the incidence and associated risk factors in older patients remain poorly *** study aimed to assess the incidence,identify risk factors,and evaluate their impact on survival outcomes among older patients with hematological ***:This retrospective single-center study analyzed data from 163 patients,focusing on the occurrence of second primary *** incidence rates were calculated,and risk factor analysis was conducted using a competing risk ***:Among 124 eligible patients with a total follow-up duration of 572.57 person-years,the incidence rate of second primary neoplasms was 15.72/1000 *** standardized incidence ratio(SIR)was 0.81(95%confidence interval[CI][0.39–1.48],P=0.518).History of radiotherapy emerged as a significant risk factor(subdistribution hazard ratio[SHR]=21.61[2.81–166.14],P=0.003),whereas regular natural killer(NK)cell infusion was associated with reduced risk(SHR=3.25 e8[9.81 e9–1.08 e7],P<0.001).Conclusions:These findings underscore the importance of informing older patients with hematological malignancies about the long-term risks of second primary *** providers should carefully weigh risk factors when formulating treatment *** results are valuable for investigating the fundamental principles underlying the occurrence and progression of second primary neoplasms.

关键词： Hematological malignancies Second primary neoplasms Older Incidence Risk factors