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代谢综合征组分异常人群PM_(2.5)长期暴露与慢性肾脏疾病的关联

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卫生研究 2024年第3期53卷 427-434页

作者：赵泽濛刘露露田雪罗丽丽罗会康晓平王肖南刘相佟郭秀花罗艳侠首都医科大学公共卫生学院首都医科大学临床流行病学北京市重点实验室北京100069 首都医科大学附属北京中医医院疾控处北京100010 北京小汤山医院北京102211

目的探究细颗粒物(fine particulate matter,PM_(2.5))长期暴露与代谢综合征(metabolism syndrome,MS)组分异常人群慢性肾脏疾病(chronic kidney disease,CKD)患病风险的关联。方法基于北京市某医院健康体检数据,采用回顾性队列研究方... 详细信息

目的探究细颗粒物(fine particulate matter,PM_(2.5))长期暴露与代谢综合征(metabolism syndrome,MS)组分异常人群慢性肾脏疾病(chronic kidney disease,CKD)患病风险的关联。方法基于北京市某医院健康体检数据,采用回顾性队列研究方法收集2013—2019年体检数据。问卷调查获取人口学特征和生活习惯信息,测量血压、身高、体重和腰围,检测甘油三酯(triglyceride,TG)、空腹血糖和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)等。同时根据研究对象的地址提取经纬度进行污染物暴露数据的估计。利用Logistic回归模型分析PM_(2.5)长期暴露对MS组分异常人群CKD患病风险的估计效应。建立双污染物和多污染物模型,检验上述结果稳定性。基于年龄、是否患有MS、MS单组分异常情况及MS双组分异常情况进行相应的亚组分析。结果研究共纳入1540名基线期MS组分异常人员,研究期间患CKD者206人,PM_(2.5)两年年均浓度[中位数(四分位间距)]为57.57(17.61)μg/m^(3)。PM_(2.5)长期暴露与MS组分异常人群CKD患病风险增加的关联有统计学意义,PM_(2.5)暴露每增加10μg/m^(3),CKD的患病风险增加2.26倍(OR=3.26,95%CI 2.72~3.90)。双污染物和多污染物模型结果提示,在控制同期其它空气污染物的混杂后,PM_(2.5)长期暴露与MS组分异常人群CKD患病风险增加的关联仍然稳定。亚组分析结果发现,年龄≥45岁,未患MS、TG<1.7 mmol/L、HDL-C≥1.04 mmol/L、未患高血压、患有中心性肥胖和高血糖的人群中PM_(2.5)与CKD相关健康影响更强。结论长期暴露于PM_(2.5)后,MS组分异常人群CKD患病风险增加。年龄≥45岁的中老年人,以及患有中心性肥胖和高血糖者应成为重点关注人群。

关键词：空气污染细颗粒物长期暴露慢性肾脏疾病代谢综合征组分

Ozonation of o-phenylenediamine in the presence of hydrogen peroxide by high-gravity technology

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Chinese Journal of Chemical Engineering 2018年第3期26卷 601-607页

作者： Moses Arowo zemeng zhao Guangjun Li Guangwen Chu Baochang Sun Lei Shao State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical Technology Beijing 100029 China Department of Chemical & Process Engineering Moi University 3900-3100 Eldoret Kenya Research Center of the Ministry of Education for High Gravity Engineering and Technology Beijing University of Chemical Technology Beijing 100029 China Beijing Yanjing Beer Co. Ltd. Beijing 101300 China

The study herein investigated the effectiveness of simultaneous use of ozone and hydrogen peroxide(O_3/H_2O_2 process) to degrade o-phenylenediamine(o-PDA) in a simulated wastewater. A rotor–stator reactor(RSR) was employed to create a high-gravity environment in order to enhance ozone-liquid mass transfer rate and possibly improve the degradation rate of o-PDA. The degradation efficiency of o-PDA(η) as well as the overall gas-phase volumetric mass transfer coefficient(KGa) were determined under different operating conditions of H_2O_2 concentration, initial o-PDA concentration, temperature of reaction, initial p H and rotation speed of RSR in attempt to establish the optimal conditions. Chemical oxygen demand reduction rate(rCOD) of wastewater treated at a particular set of conditions was also analyzed. Additionally, the intermediate products of degradation were identified using a gas chromatography-mass spectrometer(GC/MS) to further evaluate the extent of o-PDA degradation as well as establish its possible degradation pathway. Results were validated by comparison with those of sole use of ozone(O_3 process), and it was noted that η, KGa and rCODachieved by O_3/H_2O_2 process was 24.4%,31.6% and 25.2% respectively higher than those of O_3 process, indicating that H_2O_2 can greatly enhance ozonation of o-PDA. This work further demonstrates that an RSR can significantly intensify ozone-liquid mass transfer rate and thus provides a feasible intensification means for the ozonation of o-PDA as well as other recalcitrant organics.

关键词：氢过氧化物技术 H2O2 转移系数操作条件旋转速度反应堆转移率

Long-term exposure to air pollution and cerebrovascular disease:findings from Beijing Health Management Cohort study

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Frontiers of Environmental Science & Engineering 2023年第7期17卷 79-89页

作者： Yuhan zhao Xiaoping Kang Xue Tian Lulu Liu zemeng zhao Lili Luo Lixin Tao Xiangtong Liu Xiaonan Wang Xiuhua Guo Juan Xia Yanxia Luo School of Public Health Capital Medical UniversityBeijing 100069China Beijing Municipal Key Laboratory of Clinical Epidemiology Capital Medical UniversityBeijing 100069China Beijing Xiaotangshan Hospital Beijing 102211China

The relationship between air pollution and cerebrovascular disease has become a popular topic,yet research findings are highly *** study aims to investigate this association based on detailed individual health data and a precise evaluation of their exposure *** integrated models of generalized additive model,land use regression model and back propagation neural network were used to evaluate the exposure *** doubly robust additive model was conducted to explore the association between cerebrovascular disease and air pollution after adjusted for demographic characteristics,physical examination,disease information,geographic and socioeconomic status.A total of 25097 subjects were included in the Beijing Health Management Cohort from 2013 to *** a 1µg/m^(3)increase in the concentrations of PM_(2.5),SO_(2)and NO_(2),the incidence risk of cerebrovascular disease increased by 1.02(95%CI:1.008–1.034),1.06(95%CI:1.034–1.095)and 1.02(95%CI:1.010–1.029)*** CO exposure could decrease the risk,with an odds ratio of 0.38(95%CI:0.212–0.626).In the subgroup analysis,individuals under the age of 50 with normal BMI were at higher risk caused by PM2.5,and So2 was considered more hazardous to ***,the protective effect of CO on women and those with normal BMI was *** reduction of long-term exposure to PM2.5,SO_(2)and NO_(2)would lead to substantial benefits for decrease the risk of cerebrovascular disease especially for the health of the susceptible individuals.

关键词： Air pollution Cerebrovascular disease Incidence Long-term exposure Doubly robust additive model

Automatic modeling algorithm of stochastic error for inertial sensors

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Control Theory and Technology 2024年第1期22卷 81-91页

作者： Luodi zhao Long zhao School of Automation Science and Electrical Engineering Beihang UniversityBeijing100191China Digital Navigation Center Beihang UniversityBeijing100191China Science and Technology on Aircraft Control Laboratory Beihang UniversityBeijing100191China

This paper proposes an automatic algorithm to determine the properties of stochastic processes and their parameters for inertial error. The proposed approach is based on a recently developed method called the generalized method of wavelet moments (GMWM), whose estimator was proven to be consistent and asymptotically normally distributed. This algorithm is suitable mainly (but not only) for the combination of several stochastic processes, where the model identification and parameter estimation are quite difficult for the traditional methods, such as the Allan variance and the power spectral density analysis. This algorithm further explores the complete stochastic error models and the candidate model ranking criterion to realize automatic model identification and determination. The best model is selected by making the trade-off between the model accuracy and the model complexity. The validation of this approach is verified by practical examples of model selection for MEMS-IMUs (micro-electro-mechanical system inertial measurement units) in varying dynamic conditions.

关键词： GMWM Stochastic process Inertial sensor Sensor calibration Error model Allan variance

Meeting the challenges of invasive alien species

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National Science Review 2024年第3期11卷 296-298页

作者： Weijie zhao NSR news

The Xinjiang Uygur Autonomous Region of China is famous for its tomato production. Abundant sunshine, large day–night temperature difference and the abundant irrigation by snowmelt from the Tianshan Mountains produce...

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Ling-Ling Chen: RNA has its own features;don't study it as a protein

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National Science Review 2024年第2期11卷 301-305页

作者： Weijie zhao NSR

Non-coding RNA(ncRNA) has been a very active research area over the past 30 years. From small nc RNA – the discovery of RNA interference won the lead researchers the Nobel Prize, to long ncRNA(lncRNA), which has attracted much attention in recent years, various nc RNAs participate in all kinds of biological processes and show a variety of biomedical application prospects.

关键词： RNA

One dimensional CeO_(2) nanorods/poly(ethylene oxide) solid composite electrolyte for all-solid-state lithium-ion batteries

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Journal of Rare Earths 2024年第3期42卷 570-577,I0005页

作者： Yudi Guo Erqing zhao Xiaofang zhao Shuailei Liu School of Chemistry and Materials Engineering Xinxiang UniversityXinxiang453003China School of Chemistry and Chemical Engineering Henan Institute of Science and TechnologyXinxiang453003China

The research of poly(ethylene oxide)(PEO)-based solid composite electrolyte with high ionic conductivity and excellent interfacial stability is the key to the development of all-solid-state lithium-ion batteries(ASSLIBs). Herein, uniform nanorod structured CeO_(2) fillers were controllably synthesized by electrospinning, which were subsequently filled into PEO polymer to prepare CeO_(2)/PEO solid composite electrolyte. The addition of CeO_(2) nanorods can reduce both the glass transition temperature and the melting point of PEO polymer, and also interact with PEO and lithium bis(trifluoromethanesulphonyl)imide(LITFSI) by Lewis acid—base reaction. Therefore, the solid composite electrolyte exhibits a high ionic conductivity of 4.52 × 10^(-4)S/cm, a wide electrochemical stability window of about 4.8 V, and a good interfacial stability with Li at 55℃. Moreover, the LiFePO_4/Li ASSLIB divulges the discharging specific capacity of 165, 162, 156 and 146 mA,h/g at 0.2, 0.5, 1 and 2 C, respectively, and achieves the capacity retention of 90.3% after 150 cycles at 0.5 C. Consequently, one dimensional CeO_(2) nanorods can be considered as an alternative filler for polymeric solid electrolyte.

关键词： Poly(ethylene oxide) Solid composite electrolyte CeO_(2)nanorods Ionic conductivity Rare earths

A DIRECT DISCONTINUOUS GALERKIN METHOD FOR TIME FRACTIONAL DIFFUSION EQUATIONS WITH FRACTIONAL DYNAMIC BOUNDARY CONDITIONS

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Journal of Computational Mathematics 2024年第1期42卷 156-177页

作者： Jingjun zhao Wenjiao zhao Yang Xu School of Mathematics Harbin Institute of TechnologyHarbin 150001China

This paper deals with the numerical approximation for the time fractional diffusion problem with fractional dynamic boundary *** well-posedness for the weak solutions is studied.A direct discontinuous Galerkin approach is used in spatial direction under the uniform meshes,together with a second-order Alikhanov scheme is utilized in temporal direction on the graded mesh,and then the fully discrete scheme is ***,the stability and the error estimate for the full scheme are analyzed in *** experiments are also given to illustrate the effectiveness of the proposed method.

关键词： Time fractional diffusion equation Numerical stability Convergence

pyIFPNI:A package for querying and downloading plant fossil data from the IFPNI

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Plant Diversity 2024年第2期46卷 280-282页

作者： Bailong zhao State Key Laboratory of Plant Diversity and Specialty Crops Institute of BotanyChinese Academy of SciencesBeijing100093China University of Chinese Academy of Sciences Beijing100049China

The International Fossil Plant Names Index(IFPNI,2014-onwards)not only serves as an online gateway to the fossil plant name registry for the global scientific community,but also serves as a comprehensive and dynamic archive of fossil plants(Doweld,2016,2022).Since its establishment in 2014,the IFPNI has accumulated more than 80,000 entries of fossil plant names,along with information on over 10,000 documents and over 6000 paleobotanists,all supported by exhaustive data,demonstrating the scope of the IFPNI's work(IFPNI,2014-onwards).

关键词： plant fossil