检索结果-南通市图书馆

Field evaluation of COVID-19 rapid antigen test:Are rapid antigen tests less reliable among the elderly?

World Journal of Clinical Cases 2022年第19期10卷 6456-6463页

作者： Irena Tabain Djivo Cucevic Nikola Skreb Anna Mrzljak Ivana Ferencak zeljka hruskar Anita Misic Josipa Kuzle Ana Marija Skoda Hrvojka Jankovic Tatjana Vilibic-Cavlek Department of Virology Croatian Institute of Public HealthZagreb 10000Croatia Department of Emergency Medicine Institute of Emergency Medicine of the City of ZagrebZagreb 10000Croatia School of Medicine University of ZagrebZagreb 10000Croatia Department of Gastroenterology and Hepatology University Clinical Hospital ZagrebZagreb 10000Croatia

BACKGROUND The global outbreak of coronavirus disease 2019(COVID-19)leads to the development of accessible and cost-effective rapid antigen-detection tests(RATs),as quick and accurate diagnosis is crucial to curb the *** To evaluate the Humasis COVID-19 Ag Test(Humasis Co.,Ltd.,Gyeonggi-do,Republic of Korea)in the diagnosis of severe acute respiratory syndrome coronavirus-2(SARS-CoV-2).METHODS This retrospective study was carried out at the Croatian Institute of Public Health and included patients with clinical symptoms of COVID-19 lasting no longer than 5 d prior to testing,whose nasopharyngeal swabs were primarily tested with *** RAT samples underwent confirmatory real-time reverse transcription-polymerase chain reaction(RT-PCR).Diagnostic efficacy was determined compared to *** patients were divided into three age groups(65 years).Statistical analysis was performed with the significance level set at P<*** total,2490 symptomatic patients were tested;953 samples were positive on RAT,and 1537 *** negative RAT samples were subjected to RT-PCR;266 samples were positive andmarked as false-negative results on *** calculated negative predictive value as a measure ofRAT efficacy was 82.69%.The χ^(2) test and Kruskal-Wallis test showed a significant difference in theproportion of false negatives(P<0.001)and RT-PCR cycle(Ct)values for false-negative RATs(P=0.012)among the age *** young age group was significantly less likely to be falsenegative,whereas the false negatives from the elderly group experienced significantly lower Ctvalues than the other two age *** RAT demonstrated satisfactory performance with more reliable results in *** COVID-19 Ag RAT is potentially a valuable tool in areas where access tomolecular methods is limited;however,RT-PCR remains a gold standard for SARS-CoV-2detection.

关键词： Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus-2 Rapid antigen test Real-time reverse transcription-polymerase chain reaction Croatia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Parvovirus B19 status in liver,kidney and pancreas transplant candidates:A single center experience

引用

World Journal of Transplantation 2022年第11期12卷 378-387页

作者： Bojana Simunov Anna Mrzljak zeljka Jurekovic Snjezana Zidovec Lepej Ana Bainrauch Jadranka Pavicic Saric zeljka hruskar Leona Radmanic Tatjana Vilibic-Cavlek Department of Nephrology Merkur University HospitalZagreb 10000Croatia Department of Gastroenterology and Hepatology University Clinical Hospital ZagrebZagreb 10000Croatia School of Medicine University of ZagrebZagreb 10000Croatia Department of Immunological and Molecular Diagnostics University Hospital for Infectious Diseases“Dr.Fran Mihaljevic”Zagreb 10000Croatia Department of Medicine Merkur University HospitalZagreb 10000Croatia Department of Anesthesiology Merkur University HospitalZagreb 10000Croatia Department of Virology Croatian Institute of Public HealthZagreb 10000Croatia

BACKGROUND Parvovirus B19(B19V)is associated with a wide range of clinical *** major presentation is erythema ***,a persistent infection may cause pure red cell aplasia and chronic anemia in immunocompromized *** B19V seroprevalence varies with age and geographical *** To determine the B19V serological status and DNAemia in kidney,liver,and pancreas transplant *** Patients who underwent kidney,liver,or simultaneous kidney and pancreas/liver transplantation between January 2021 and May 2022 were included in the *** serum samples were collected before *** detection of B19V DNA,a LightMix Kit B19V EC(TIB MOLBIOL,Berlin,Germany)was used.B19V IgM and IgG antibodies were detected using a commercial ELISA test(Euroimmun,Lübeck,Germany).RESULTS One hundred and thirty-one transplant candidates were included in the study,71.0%male,with an average age of 53.27 years±12.71 *** were 68.7%liver,27.5%kidney,3.0%simultaneous pancreas/kidney transplant(SPKT),and 0.8%simultaneous liver/kidney transplant *** patients had detectable B19V DNA.B19V IgG seroprevalence was 77.1%.No acute or recent infections were detected(IgM antibodies).There was no difference in the mean age of seronegative and seropositive patients(51.8 years±12.9 years vs 53.7 years±12.7 years,t=-0.603;P=0.548).Although seropositivity was lower in patients aged less than 30 years(66.6%)compared to the patients aged 30-59 years and>60 years(80.4%and 78.1%,respectively),this difference was not *** addition,there was no difference in seropositivity between male and female transplant candidates,76.3%and 78.9%(χ^(2)=0.104;P=0.748).The seroprevalence did not differ among organ recipients,with 77.8%,80.6%,and 50.0%for liver,kidney,and SPKT,respectively,(χ^(2)=5.297;P=0.151).No significant difference was found in the seroprevalence in kidney transplant patients according to dialysis *** was 71.

关键词： Parvovirus B19 Seroprevalence DNA Kidney transplantation Liver transplantation Pancreas transplantation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：