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Open Journal of Anesthesiology 2013年第2期3卷 93-96页

作者： Carrie rosenberg Ricardo Gomez Department of Anesthesiology New Mexico Veterans Affairs Health Care System Albuquerque USA

Undiagnosed pheochromocytoma is a cause of hypertension intraoperatively. Hypertension from pheochromocytoma catecholamine secretion is potentially fatal and requires immediate treatment with cardiac afterload reduction and preload augmentation for end-organ protection. Diagnosis and management in the acute period can be complex in the context of co-existing disease, other possible causes of hypertension, and the anesthetized patient who is unable to provide historical clues. This case report highlights the plausibility that pheochromocytomas may be more likely to present sub-clinically in elderly patients with severe vascular disease, so we suggest the potential utility of studying whether reduced vascular responsiveness is protective in any way to catecholamine load. Above all, as an increasing number of case reports of pheochromocytoma discovery intra-operatively emerge, many with catastrophic outcomes, the development value and feasibility of a rapid, on-site blood metanephrine test should be considered. Existing diagnostic methods of pheochromocytoma are relatively time-consuming and not useful in the acute situation.

关键词： Pheochromocytoma Metanephrines Catecholamines Perioperative Hypertension

Atlas of Clinical Neurology 3rd ed. 2012

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serological surveillance for sARs-CoV-2 antibodies among students,faculty and staff within a large university system during the pandemic

2009年

作者： Roger N. rosenberg

来源：畅想之星图书光盘版（南... 评论

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World Journal of Virology 2025年第1期14卷 99-107页

作者： Marcos G Pinheiro Gabriela G O Alves Maria Eduarda R Conde sofia L Costa Regina C s sant’Anna Isa M F Antunes Mônica C Carneiro Fabio s Ronzei Julia C scaffo Felipe R Pinheiro Lialyz s Andre Helvecio C Povoa Valéria T Baltar Fabíola Giordani Eduarda s Hemerly Gisele C Alexandre Karla C de Paula Márcio Watanabe Antonio Claudio L da Nóbrega Jackeline Christiane P Lobato Fabio Aguiar-Alves Laboratory of Molecular Epidemiology and Biotechnology Rodolpho Albino University LaboratoryFluminense Federal UniversityNiterói 24241000Rio de JaneiroBrazil Estácio de sáUniversity Nova Friburgo 28611135Rio de JaneiroBrazil Pathology Program Medicine schoolFluminense Federal UniversityNiterói 24070090Rio de JaneiroBrazil Department of Pharmaceutical sciences Lloyd L.Gregory School of PharmacyPalm Beach Atlantic UniversityWest Palm BeachFL 33401United States Health Institute of Nova Friburgo Fluminense Federal UniversityNova Friburgo 28613001Rio de JaneiroBrazil Department of Epidemiology and Biostatistics Institute of Collective Health(ISC)Fluminense Federal UniversityNiterói 24033900Rio de JaneiroBrazil Institute of Physical Education Fluminense Federal UniversityNiterói 24020005Rio de JaneiroBrazil Department of statistics Fluminense Federal UniversityNiterói 24210200Rio de JaneiroBrazil Department of Physiology and Pharmacology Fluminense Federal UniversityNiterói 24210130Rio de JaneiroBrazil

BACKGROUND At the end of December 2019,the world faced severe acute respiratory syndrome-coronavirus 2(sARs-CoV-2),which led to the outbreak of coronavirus disease 2019(COVID-19),associated with respiratory *** virus has shown significant challenges,especially for senior citizens,patients with other underlying illnesses,or those with a sedentary *** tests conducted early on have helped identify how the virus is transmitted and how to curb its *** study hypothesis was that the rapid serological test for sARs-CoV-2 antibodies could indicate the immunoreactive profile during the COVID-19 pandemic in a university *** To conduct active surveillance for serological expression of anti-sARs-CoV-2 antibodies in individuals within a university setting during the COVID-19 *** This sectional study by convenience sampling was conducted in a large university in Niteroi-RJ,Brazil,from March 2021 to July *** study population consisted of students,faculty,and administrative staff employed by the university.A total of 3433 faculty members,60703 students,and 3812 administrative staff were invited to *** were gathered through rapid serological tests to detect immunoglobulin(Ig)M and IgG against ***χ²or Fisher's exact test was used to conduct statistical analysis.A 0.20 significance level was adopted for variable selection in a multiple logistic regression model to evaluate *** A total of 1648 individuals were enrolled in the *** proportion of COVID-19 positivity was 164/1648(9.8%).The adjusted logistic model indicate a positive association between the expression of IgM or IgG and age[odds ratio(OR)=1.16,95%CI:1.02-1.31](Ps who had been in contact with a COVID-19-positive case(OR=3.49,95%CI:2.34-5.37)(Pse who had received the COVID-19 vaccine(OR=2.33,95%CI:1.61-3.35)(Psocial isolation(OR=0.59,95%CI:0.41-0.84)(Psho

关键词： serological surveillance sARs-CoV-2 antibodies COVID-19 serological rapid test Risk factors for COVID-19

self-Assembly of Colloidosome shells on Drug-Containing Hydrogels

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Journal of Biomaterials and Nanobiotechnology 2011年第1期2卷 1-7页

作者： Rachel T. rosenberg Nily Dan 不详

Colloidosomes are composed of an aqueous or hydrogel corethat is coated by a semi-permeable colloidal shell. The properties of the shell can be varied to control the rate of release of encapsulated components such as drugs. specifi-cally, the pores formed between the colloidal particles suppress transport of large components, while allowing diffusion of smaller ones. self-assembly of colloidal particles on hydrogel films is a convenient method forcolloidosome synthesis, but to date little is known regarding the effect (if any) of the encapsulated drug on the shell packing density. In this paper we examined self-assembly of colloidal shells on alginate films containing four model drugs: aspirin, caffeine, theophylline and theobromine. We find that the packing density in the colloidal shells is low for all drugs, and ranges between 0.16 and 0.3. There is no clear correlation between drug properties (in particular, water solubility) and the packing density of the self-assembled colloidal shell.

关键词： Drug delivery Diffusion Colloids Colloidosomes

Covid-19 and Immunity in the Elderly

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Journal of Geriatric Medicine 2020年第1期2卷 1-4页

作者： Hom Nath Chalise Edwin rosenberg Faculty Member Department of Public HealthNobel College affiliated to Pokhara UniversitySinamangalKathmanduNepal Vice President Population Association of NepalKathmandu Nepal Department of sociology Appalachian State UniversityBooneNorth Carolina28608USA

Population ageing is an issue of worldwide *** are living longer due to advances in education,technology,medicine,food distribution,and public *** the COVID-19 pandemic has significant global impacts,in many countries the elderlyface threats and challenges that are unique and disproportionately *** such threat is that aging results in a decline in immune function,meaning elderly bodies respond more slowly and less effectively to external threats like *** at individual,family,community and societal levels should take into account the heightened vulnerability of older adults during this pandemic.

关键词： Coronavirus COVID-19 Older adults Immune system

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噩运之钻“希望之星”

疯狂英语（初中天地） 2007年第11期 50-53页

作者： Jennifer rosenberg KC

"希望之星"(因其主人亨利·菲利普·霍普的姓氏意为"希望"而得此译名)是世间罕有的蓝色钻石,几个世纪以来辗转于各大皇室贵族之手。据说拥有者都会被诅咒,不得善终。不管你是否相信诅咒之说,这颗传世名钻总会引起人们的无限退想。这个... 详细信息

"希望之星"(因其主人亨利·菲利普·霍普的姓氏意为"希望"而得此译名)是世间罕有的蓝色钻石,几个世纪以来辗转于各大皇室贵族之手。据说拥有者都会被诅咒,不得善终。不管你是否相信诅咒之说,这颗传世名钻总会引起人们的无限退想。这个诅咒是真的吗?希望之星魔力何在?为什么这样一颗钻石最终会成为博物馆的展品?请看——

关键词：希望之星卡地亚菲利普路易十四克莱恩

Identification and Charaterization of Genes Encoding Melanoma Antigens Recognized by Tumor-infiltrating Lymphocytes

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中国肿瘤生物治疗杂志 1995年第4期2卷 243-244页

作者： Rong-FuWang stevenA.rosenberg NIH NCIBethesdeMD20892USA surgeryBranch NationalCancerInstituteNIHBethesdaMD20892USA

Adoptive transfer of tumor infiltrating lymphocytes (TILs) into the autologous patient with melanoma resulted in the objective regression of tumor, suggesting that these TILs recognize tumor rejection antigens on the ... 详细信息

关键词：基因编码黑素瘤免疫抗原肿瘤细胞淋巴细胞

Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion

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Neural Regeneration Research 2025年第4期20卷 1192-1206页

作者： Tyler A.smith Liwen Zhou Cameron L.Ghergherehchi Michelle Mikesh Cathy Z.Yang Haley O.Tucker JuliAnne Allgood Jared s.Bushman George D.Bittner Department of Molecular Biosciences University of Texas at AustinAustinTXUSA Department of Neuroscience University of Texas at AustinAustinTXUSA Division of Pharmaceutical sciences University of WyomingLaramieWYUSA

Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal ***,such peripheral nerve allografts undergo immunological rejection by the host immune *** contrast,peripheral nerve injuries repaired by polyethylene glycol fusion of peripheral nerve allografts exhibit excellent behavioral recovery within weeks,reduced immune responses,and many axons do not undergo Wallerian *** relative contribution of neurorrhaphy and polyethylene glycol-fusion of axons versus the effects of polyethylene glycol per se was unknown prior to this *** hypothesized that polyethylene glycol might have some immune-protective effects,but polyethylene glycol-fusion was necessary to prevent Wallerian degeneration and functional/behavioral *** examined how polyethylene glycol solutions per se affect functional and behavioral recovery and peripheral nerve allograft morphological and immunological responses in the absence of polyethylene glycol-induced axonal ***-type sciatic nerve injuries in outbred sprague–Dawley rats were repaired according to a modified protocol using the same solutions as polyethylene glycol-fused peripheral nerve allografts,but peripheral nerve allografts were loose-sutured(loose-sutured polyethylene glycol)with an intentional gap of 1–2 mm to prevent fusion by polyethylene glycol of peripheral nerve allograft axons with host *** to negative control peripheral nerve allografts not treated by polyethylene glycol and in contrast to polyethylene glycol-fused peripheral nerve allografts,animals with loose-sutured polyethylene glycol peripheral nerve allografts exhibited Wallerian degeneration for all axons and myelin degeneration by 7 days postoperatively and did not recover sciatic-mediated behavioral functions by 42 days *** morphological signs of rejection,such as col

关键词： allograft rejection axotomy macrophage myelin nerve repair polyethylene glycol(PEG) sciatic nerve T cell transplantation Wallerian degeneration

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不确定性与创新文化

自然辩证法研究 2001年第Z1期17卷 9-12页

作者： Nathan rosenberg 宋建元 stanford University America美国斯坦福大学　

　　1　　在考虑科学和技术文化时,有一个在讨论中起支配作用的关键词,即不确定性.当在科学和技术领域进行研究时,其研究结果不可能事先预测,简单的现实是,当必须获得并不可利用的信息时,研究仍在进行.但是,由于各种原因,大多数高技术... 详细信息

　　1　　在考虑科学和技术文化时,有一个在讨论中起支配作用的关键词,即不确定性.当在科学和技术领域进行研究时,其研究结果不可能事先预测,简单的现实是,当必须获得并不可利用的信息时,研究仍在进行.但是,由于各种原因,大多数高技术领域的研究并没有带来有商业价值的发现.……

关键词：不确定性高技术领域支配作用商业价值科学技术文化关键词预测信息

北京市老年人居家养老满意度与机构养老意愿研究

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地理科学进展 2015年第12期34卷 1577-1585页

作者：余杰 Mark W.rosenberg 程杨女王大学地理系北京师范大学地理学与遥感科学学院北京00875

在20世纪婴儿潮、计划生育政策和人口死亡率下降的影响下,中国过去几十年中人口老龄化的速度不断加快。中国政府已经将"居家养老"和"养老服务社会化"确定为应对人口老龄化的基本方针。要想实现引导老年人居家养老的目标,必须充分把握老... 详细信息

在20世纪婴儿潮、计划生育政策和人口死亡率下降的影响下,中国过去几十年中人口老龄化的速度不断加快。中国政府已经将"居家养老"和"养老服务社会化"确定为应对人口老龄化的基本方针。要想实现引导老年人居家养老的目标,必须充分把握老年人现有生活的实体环境和社会环境。本文的目标是剖析老年人对实体与社会环境的认知,并阐明其与居家养老体验的关联性,并进而研究其对老年人入住养老机构意愿的影响程度。研究北京对社会养老服务的政策具有典型意义,因此本文选择北京市作为案例研究区。研究结果表明,老年人对实体和社会环境的负面评价与其对居家养老体验的负面认知是有关联的,对拥有机构养老意愿的老年人可以通过人口学与健康属性得以细分。此外,子女的看望对老年人居家养老满意度及其机构养老意向具有重要的影响。

关键词：就地养老健康地理学老年人群社会环境北京