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Stepping up after spinal cord injury:negotiating an obstacle during walking

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Neural Regeneration Research 2025年第7期20卷 1919-1929页

作者： Alain Frigon Charly g.Lecomte Department of Pharmacology-Physiology Faculty of Medicine and Health SciencesUniversitéde SherbrookeCentre de recherche du Centre Hospitalier Universitaire de SherbrookeSherbrookeQCCanada

Every day walking consists of frequent voluntary modifications in the gait pattern to negotiate *** spinal cord injury,stepping over an obstacle becomes *** over an obstacle requires sensorimotor transformations in several structures of the brain,including the parietal cortex,premotor cortex,and motor *** information and planning are transformed into motor commands,which are sent from the motor cortex to spinal neuronal circuits to alter limb trajectory,coordinate the limbs,and maintain *** spinal cord injury,bidirectional communication between the brain and spinal cord is disrupted and animals,including humans,fail to voluntarily modify limb trajectory to step over an ***,in this review,we discuss the neuromechanical control of stepping over an obstacle,why it fails after spinal cord injury,and how it recovers to a certain extent.

关键词： biomechanics locomotion neurophysiology obstacle negotiation spinal cord injury

Projective Hilbert modules and sequential approximations

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Science China Mathematics 2025年第1期 137-168页

作者： Lawrence g.Brown Huaxin Lin Department of Mathematics Purdue University Department of Mathematics East China Normal University Department of Mathematics University of Oregon Shanghai Institute for Mathematics and Interdisciplinary Sciences

We show that when A is a separable C*-algebra,every countably generated Hilbert A-module is projective（with bounded module maps as morphisms）.We also study the approximate extensions of bounded module *** the case where A is a σ-unital simple C*-algebra with strict comparison,and every strictly positive lower semicontinuous affine function on quasitraces can be realized as the rank of an element in the Cuntz semigroup,we show that the Cuntz semigroup is equivalent to unitarily equivalent classes of countably generated Hilbert A-modules if and only if A has stable rank one.

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Bioelectronic medicine in modulation of cortical spreading depolarization and beyond

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Neural Regeneration Research 2025年第2期20卷 481-482页

作者： Khaled Alok Timothy g.White Chunyan Li Department of Neurosurgery Donald and Barbara Zucker School of Medicine at Hofstra/NorthwellHempsteadNYUSA Translational Brain Research Laboratory The Feinstein Institutes for Medical ResearchManhassetNYUSA

Bioelectronic interventions,specifically trigeminal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading depolarizations(CSDs)accompanied by compromised cerebral perfusion may exacerbate neurological *** pharmacological interventions have demonstrated initial potential in addressing CSDs,a standardized treatment approach has not yet been *** objective of this perspective is to explore emerging bioelectronic methodologies for addressing CSDs,particularly emphasizing TNS,and to underscore TNS’s capacity to enhance neurovascular coupling and cerebral perfusion.

关键词： cerebral perfusion electronic

Effect of 5-Aza-2’-deoxycytidine on immune-associated proteins in exosomes from hepatoma

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World Journal of gastroenterology 2010年第19期16卷 2371-2377页

作者： gao-wa Sanren Department of Histology and Embryology Inner Mongolia Medical College Hohhot 010010 Inner Mon-golia Autonomous Region China

AIM: To study the effect of 5-Aza-2’-deoxycytidine (5-Aza-CdR) on heat shock protein 70 (HSP70), human leucocyte antigen-Ⅰ (HLA-Ⅰ) and NY-ESO-1 proteins in exosomes produced by hepatoma cells, Hepg2 and Hep3B. METHODS: Exosomes derived from Hepg2 and Hep3B cells treated with or without 5-aza-CdR were isolated and purified by ultrafiltration centrifugation and sucrose gradient ultracentrifugation. The number of exosomes was counted under electron microscope. Concentration of proteins in exosomes was measured by bicinchoninic acid protein assay. Expression of HSP70, HLA-Ⅰ and NY-ESO-1 proteins in exosomes was detected by Western blotting and immunoelectron microscopy. mRNA expression of p53 gene was detected by reverse transcription polymerase chain ***: The mRNA expression of p53 gene was increased in both hepatoma cell lines after treatment with 5-Aza-CdR. The number of exosomes and the concentration of total proteins in exosomes were increased signifi cantly after treatment with 5-aza-CdR (P g showed that the HSP70, HLA-Ⅰ and NY-ESO-1 proteins were increased in exosomes produced by both hepatoma cell lines. CONCLUSION: 5-aza-CdR, an inhibitor of DNA methyltransferase, can increase exosomes produced by hepatoma cells and immune-associated protein component of exosomes, which may be mediated by p53 gene upregulation and 5-Aza-CdR demethylation.

关键词： 5-Aza-2’-deoxycytidine Exosome Immu-nomolecule Hepatoma cell

Impact of Zika virus non-structural protein mutations on hippocampal damage

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Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa M.g.Cassiano Roney S.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNS)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

Identities Involving Powers and Inverse of Binomial Coefficients

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Journal of Mathematical Research and Exposition 2011年第6期31卷 1021-1029页

作者： Wu Yun g ao wa Department of Mathematics College of Sciences and Technology Inner Mongolia University Inner Mongolia 010021 P. R. China

In this paper,we give several identities of finite sums and some infinite series involving powers and inverse of binomial coefficients,which extends the results of ***.

关键词： inverse of binomial coefficient identities stirling numbers

The use of Phanerochaete chrysosporium,Trichoderma harzianum and Trichoderma viride for biogas production

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Studies in Fungi 2020年第1期5卷 368-380页

作者： Mahmoud YA-g Awadalla OA Estafanous AN Etawy wa Tanta University Faculty of ScienceBotany and Microbiology DepartmentMycology Research Lab.Tanta 31527Egypt Agriculture Microbiology Department SoilWater and Environment Research InstituteAgriculture Research CenterCairoEgypt

The expanding cost of ordinary fuel in urban zones requires the investigation of other vitality *** exploitation of agricultural wastes for biogas production could protect our environment and can also solve emerging energy crises *** chrysosporium,Trichoderma virdie and Trichoderma harzianum were used to ferment rice straw and cattle dung for production of compost and *** yield was determined using displacement technique,using acidified water(1 N H_(2)SO_(4))to prevent solubilization of carbon dioxide contained in the *** results showed that the highest rate of biogas and methane were recorded with treated rice straw mixed with cattle dung where the amount of production from the total gas was 51.84 of biogas and 37.86 of methane per Liter(L)/Kilogram(Kg)of fermented ***,the results showed that the consumed biogas and methane related to volatile solids gave the highest amount with untreated rice straw(86.32 and 56.72 L/Kg respectively)followed by treated rice straw and untreated and treated mixtures of rice straw and cattle dung *** results also showed that the highest bacterial count was obtained from fungi treated rice straw mixed with cattle dung(125×10^(3)cells/g)followed by treated rice straw(32×10^(3)cells/g).This study confirms that ***,*** and *** significantly speed up the process of aerobic and anaerobic fermentation of rice straw in respect to biogas and methane production.

关键词： Aerobic fermentation Anaerobic fermentation Methane Rice straw

A building-based data capture and data mining technique for air quality assessment

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Frontiers of Environmental Science & Engineering 2011年第4期5卷 543-551页

作者： Ni SHENg U wa TANg Faculty of Management and Administration Macao University of Science and TechnologyMacaoChina Department of Civil and Environmental Engineering University of MacaoMacaoChina Dirccao dos Servicos de Proteccao Ambiental MacaoChina

Recently,a building-based air quality model system which can predict air quality in front of individual buildings along both sides of a road has been *** the Macao Peninsula as a case study,this paper shows the advantages of building-based model system in data capture and data *** with the traditional grid-based model systems with input/output spatial resolutions of 1-2 km,the building-based approach can extract the street configuration and traffic data building by building and therefore,can capture the complex spatial variation of traffic emission,urban geometry,and air *** non-homogeneous distribution of air pollution in the Macao Peninsula was modeled in a highspatial resolution of 319 receptors·km^(-2).The spatial relationship among air quality,traffic flow,and urban geometry in the historic urban area is *** study shows that the building-based approach may open an innovative methodology in data mining of urban spatial data for environmental *** results are particularly useful to urban planners when they need to consider the influences of urban form on street environment.

关键词： traffic air pollution spatial distribution high resolution geographic information system

Xiamen after 20 Years of Ecological Transformation

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China Today 2025年第1期74卷 66-68页

作者： ZACHARY g.LUNDQUIST 不详

The efforts Xiamen has made in ecological protection over the last 20 years have helped it become a beautiful and clean *** years ago,I had the opportunity to travel to the city of Xiamen in southeastern China’s Fujian ***,due to the fact that I was in a rush,I did not have the chance to see the whole *** memory of Xiamen was its pleasant climate and unforgettable beauty-I knew if I ever got the opportunity,I would revisit this *** years went by until I was able to return to this city *** emerging from the airport,I realized that I had grown older,while Xiamen was becoming increasingly youthful and *** exactly had given this city such vitality?

关键词： Ecological Xiamen Transformation