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联合串行式和钟摆式卫星编队精确建立下一代HIP-3S地球重力场模型

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地球物理学报 2017年第8期60卷 3051-3061页

作者：郑伟许厚泽李钊伟吴凡中国空间技术研究院钱学森空间技术实验室北京100094 中国科学院测量与地球物理研究所大地测量与地球动力学国家重点实验室武汉430077

第一,基于扰动星间距离观测量对地球重力场反演精度的敏感性优于星间距离观测值的特性,本文构建了新型扰动星间距离法(DIRM).第二,有效检验了下一代HIP-3S编队的轨道稳定性,结果表明:HIP-3S编队较稳定,有利于提高地球重力场反演精度.第... 详细信息

第一,基于扰动星间距离观测量对地球重力场反演精度的敏感性优于星间距离观测值的特性,本文构建了新型扰动星间距离法(DIRM).第二,有效检验了下一代HIP-3S编队的轨道稳定性,结果表明:HIP-3S编队较稳定,有利于提高地球重力场反演精度.第三,基于扰动星间距离法,分别利用当前GRACE-2S串行式双星编队和下一代HIP-3S复合式三星编队精确反演了120阶地球重力场,在120阶处累计大地水准面精度为2.271×10^(-1)m和1.923×10^(-3)m,结果表明:HIP-3S复合式三星编队有利于建立下一代高精度和高空间分辨率的地球重力场模型.

关键词：扰动星间距离法 Hybrid-Inline-Pendulum-3S编队轨道稳定性南北条带误差卫星重力反演

Intensive cholesterol lowering with statin improves the outcomes of percutaneous coronary intervention in patients with acute coronary syndrome

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Chinese Medical Journal 2009年第6期122卷 659-664页

作者： JIA Xin-wei FU Xiang-hua ZHANG Jing GU Xin-shun FAN wei-ze wu wei-li HAO Guo-zhen LI Shi-qiang JIANG Yun-fa Department of Cardiovascular Disease Second Hospital of Hebei Medical University Shijiazhuang Hebei 050000 China

Background The incidence of no reflow phenomenon limits the clinical outcomes of percutaneous coronary intervention （PCI）. This randomized controlled study was designed to evaluate the immediate protective effects of intensive statin pretreatment on myocardial perfusion and myocardial ischemic injury during PCI.Methods Altogether 228 patients with acute coronary syndrome （ACS） were randomly assigned to standard statin group （SS group, n=115） and intensive statin group （IS group, n=-113）. Patients in the SS group received 20 mg simvastatin and patients in the IS group received 80 mg simvastatin for 7 days before PCI. Thrombolysis in myocardial infarction （TIMI） flow grade （TFG）, corrected TIMI frame count （CTFC） and TIMI myocardial perfusion grade （TMPG） of the intervened vessel were recorded before and after stent deployment. Creatine kinase （CK） isoenzyme MB, troponin I and plasma level of high sensitive-C reactive protein （hs-CRP）, P-selectin and intercellular adhesion molecule （ICAM） were measured before and 24 hours after the procedure.Results The TFG after stent deployment was significantly improved with less TIMI 0-1 and more TIMI 3 blood flow in the IS group than in the SS group （all P〈0.05）. Patients with no reflow phenomenon were less in the IS group （P〈0.001）. The CTFC was lower in the IS group than in the SS group （P 〈0.001）. TMPG was also improved in the IS group than in the SS group （P=0.001）. Although PCI caused a significant increase in CK-MB 24 hours after the procedure, the elevated CK-MB value was lower in the IS group than in the SS group （18.74±8.41 vs 21.78±10.64, P=0.018）. Similar changes were also found in troponin I （0.99±1.07 in the IS group vs 1.47±1.54 in the SS group, P=0.006）. CK-MB elevation occurred in 27.8% （32/115） of the patients in the SS group vs 15.9% （18/113） in the IS group （P=-0.030）. Myocardial necrosis was detected in 4.4% （5/115） of the patients in the SS group, whereas 0.9% （1/113） in the IS group （P=0.341）. But no myo

关键词： simvastatin myocardium perfusion percutaneous coronary intervention acute coronary syndrome no reflow phenomenon

The role of endoscopic retrograde cholangiopancreatography in perioperative period of laparoscopic cholecystectomy

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Hepatobiliary & Pancreatic Diseases International 2002年第1期1卷 114-117页

作者： wei-ze wu Ming-Hua Zheng Jian-Cheng Wang Sheng Chen From the Department of Surgery Ruijin Hospital, Shang hai Second Medical University, Shanghai 200025, China Department of Surgery Ruijin Hospital Shanghai Second Medical University Shanghai 200025 China. wuweize@***

Objective: To explore the indications and the value ofendoscopic retrograde cholangiopancreatography(ERCP)in perioperative phase of laparoscopic ***: From January 1998 to April 1999, a total of1500 consecutive laparoscopic cholecystectomies wereanalyzed. The indications for preoperative group (n=33) included elevated bilirubin level and alkalinephosphatase level, jaundice, pancreatitis, abnormalliver function, dilated bile duct and/or stones on ul-trasound or CT. The indications for postoperativegroup (n=20) included clinical signs or symptoms aswell as common bile duct stones demonstrated by in-traoperative ***: Preoperative ERCP for 32 patients (2.1%)showed abnormalities in 12 (37%). Postoperative ER-CP for 20 patients(1.3%) demonstrated abnormalitiesin 14 (70%). Super-selected criteria for preoperativeERCP would predict more than 66% ductal *** sphincterectomy and duct stones clearancewere performed in all 16 patients with documentedcommon bile duct stones. The morbidity was confinedin 2 patients with self-limited pancreatitis (3%).Conclusions: Using super-selected creteria to selectpatients for preoperative ERCP can avoid unnecessaryERCP. As soon as postoperative patients have clinicalsigns or symptoms, endoscopic treatment should beperformed.

关键词： endoscopic retrograde cholangiopancreatography endoscopic sphincterotomy perioperation laparoscopic cholecystectomy

Calcium overload in the acute myocardial ischemia/reperfusion injury

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Calcium overload in the acute myocardial ischemia/reperfusio...

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

第九届全国钙信号和细胞功能研讨会

作者： Jing-Jun Zhou,Geng-ze wei,Feng wu,Sheng-Hui Bi,Feng Gao Department of Physiology,The Fourth Military Medical University Xi’an,China,710032

Ca overload is a common phenomenon occurring during myocardial ischemia/reperfusion injury,which leads to mechanic dysfunction,arrhythmias,and cell *** no w,its underlying mechanism is still not well ***,we firstly evaluated the role of sodium/calcium exchanger(NCX) in the pathogenesis of myocardial stunning caused by brief simulated ischemia/*** data revealed that the reverse-mode activity of NCX was significantly increased during the first minutes after reperfusion,which was correlated with the increase in the diastolic cytosolic Ca *** of KB-R7943 not only blocked reverse-mode

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang zeng wei Tan Xingxing Chen Shuyuan Bai Qiong wu Yushan Chen Zhen wei Yufei Mei Yan zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

Depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 335-345页

作者： Feng Zhang Chenyang Zhang Linlin wu wei Sun Hongliang Zhang Jianhua Chen Yong Pei Songjiang Li Engineering Research Center of Ministry of Education for Carbon Emission Reduction in Metal Resource Exploitation and Utilization Hunan International Joint Research Center for Efficient and Clean Utilization of Critical Metal Mineral ResourcesSchool of Minerals Processing and BioengineeringCentral South UniversityChangsha 410083China State Key Laboratory of Mineral Processing Beijing General Research Institute of Mining&MetallurgyBeijing 100160China Hunan Provincial Key Laboratory of Micro&Nano Materials Interfaces Science College of Chemistry and Chemical EngineeringCentral South UniversityChangsha 410083China School of Resources Environment and MaterialsGuangxi UniversityNanning 530004China Department of Chemistry Xiangtan UniversityXiangtan 411105China China Railway Resource Group Co.Ltd Beijing 102300China

The depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite still lacked in-depth ***,the depression mechanism of sulfite ions on sphalerite and Pb^(2+)activated sphalerite in the flotation separation of galena from sphalerite was further systematically investigated with experiments and density functional theory(DFT)*** X-ray photoelectric spectroscopy(XPS)results,DFT calculation results,and frontier molecular orbital analysis indicated that sulfite ions were difficult to be adsorbed on sphalerite surface,suggesting that sulfite ions achieved depression effects on sphalerite through other non-adsorption ***,the oxygen content in the surface of sphalerite treated with sulfite ions in creased,which enhanced the hydrophilicity of the sphalerite and further increased the difference in hydrophilicity between sphalerite and ***,sulfite ions were chelated with lead ions to form PbSO_(3)in *** hydrophilic PbSO_(3)was more easily adsorbed on sphalerite than *** interaction between sulfite ions and lead ions could effectively inhibit the activation of *** addition the UV spectrum showed that after adding sulfite ions,the peak of perxanthate in the sphalerite treated xanthate solution was significantly stronger than that in the galena with xanthate solution,indicating that xanthate interacted more readily with sulfite ions and oxygen mo lecules within the sphalerite system,leading to the formation of ***,sulfite ions hardly depressed the flotation of ga lena and could promote the flotation of galena to some *** study deepened the understanding of the depression mechanism o sulfite ions on sphalerite and Pb^(2+)activated sphalerite.

关键词： sphalerite galena sulfite ion density functional theory depression mechanism

A mild, configurable, flexible CoNi-LDH（v）/Zn battery based on H-vacancy-induced reversible Zn2+ intercalation

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Journal of Energy Chemistry 2025年第1期100卷 498-508页

作者： Xinyue Cheng Dingsheng wu Hao Gao Qingqing Wang Pengfei Lv Sam S.Yoon Qufu wei Key Laboratory of Eco-textiles Ministry of Education Jiangnan University School of Mechanical Engineering Korea University

Flexible Zn-based batteries have attracted increasing research interest as essential components of wearable energy storage ***,the advancement of flexible aqueous Zn-based batteries based on Co-Ni layered double hydroxide （CoNi-LDH） as the cathode material is hampered by their poor cycling stability and the corrosiveness of alkaline ***,CoNi-LDH nanosheets enriched with H vacancies (CoNi-LDH（v）) were constructed on a flexible carbon cloth （CC） substrate via electrochemical deposition and *** Zn-based battery comprising CoNi-LDH（v）@CC as the cathode exhibited highly reversible conversion reactions and stable operation in 3 M ZnSO4electrolyte （pH=4）.The battery delivered an excellent specific capacity (225 mA h g-1,0.26 mA h cm-2),acceptable cycling stability（53.9%,900 cycles）,and high discharging *** abundant H vacancies served as active sites for the reversible intercalation of Zn2+and the extravasation of NO3-generated channels and space for Zn2+transport and storage,together enabling an excellent Zn2+storage ***,a sandwich-structured solid-state CoNi-LDH（v）@CC//Zn@CC battery was fabricated and was found to exhibit a noteworthy electrochemical performance and mechanical *** a proof of concept,the unencapsulated battery powered a digital watch under various deformation conditions and operated stably for 80 ***,the flexible battery displayed outstanding customizability,maintaining an open-circuit voltage of 1.42 V even after being cut *** proposed engineering strategy contributes to the realization of textiles with truly wearable energy-storage devices.

关键词： CoNi/Zn battery H vacancies Mild aqueous electrolyte Tailorable battery Wearable energy storage device

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting Li wei Zhang Jian wu Hui Hong wei Quan Xinyu Qiao Chun Cui Chenmeng Qiao weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

锆对Cr-Si-Al电阻薄膜微观结构和电性能的影响

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上海交通大学学报 2003年第2期37卷 236-240页

作者：董显平林泽伟吴建生毛立忠上海交通大学教育部高温材料及高温测试重点实验室上海200030

研究了退火态 Cr- Si- Al和 Cr- Si- Al- Zr薄膜的微观结构和电性能 .结果表明 ,溅射态非晶薄膜 Cr- Si- Al和 Cr- Si- Al- Zr在加热到 70 0°C的过程中 ,主要析出 2种晶化相 :Cr(Al,Si) 2 和 Si纳米晶化相 ,其中 Cr- Si- Al- Zr薄膜中... 详细信息

研究了退火态 Cr- Si- Al和 Cr- Si- Al- Zr薄膜的微观结构和电性能 .结果表明 ,溅射态非晶薄膜 Cr- Si- Al和 Cr- Si- Al- Zr在加热到 70 0°C的过程中 ,主要析出 2种晶化相 :Cr(Al,Si) 2 和 Si纳米晶化相 ,其中 Cr- Si- Al- Zr薄膜中的晶化相 Cr(Al,Si) 2 包含有少量 Zr原子 .Zr原子的加入抑制了晶化相的形核和长大 ,从而 Cr- Si- Al- Zr薄膜与 Cr- Si- Al薄膜相比 ,需更高的退火温度才能达到趋于零的电阻温度系数 .因此 ,Cr- Si- Al- Zr薄膜具有更好的电学稳定性能 .

关键词：电阻薄膜微观结构晶化锆电学稳定性