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Hot Deformation Behavior of Ti-6Al-4V-0.5Ni-0.5Nb Titanium Alloy

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1270-1277页

作者： ZHU Guochuan LIU Qiang SONG Shengyin HUI Songxiao YU Yang YE Wenjun QI jun tang Zhengwei XU Penghai CNPC Tubular Goods Research Institute Xi’an 710077China State Key Laboratory for Fabrication&Processing of Nonferrous Metals Beijing General Research Institute for Nonferrous MetalsBeijing 100088China China Petroleum Tarim Oilfield Company Korla 841000China

Characterization of hot deformation behavior of Ti-6Al-4V-0.5Ni-0.5Nb titanium alloy was investigated through isothermal compression at various temperatures from 750 to 1050℃and strain rate from 0.01 to 10 s^(-1).The isothermal compression experiment results showed that the peak stress of Ti-6Al-4V-0.5Ni-0.5Nb titanium alloy decreased with the temperature increasing and the strain rate *** softening mechanism was dynamic recovery below T_(β)and changed to dynamic recrystallization above T_(β).The arrheniustype relationship was used to calculate the constitutive equation of Ti-6Al-4V-0.5Ni-0.5Nb alloy in two-phase *** was found that the apparent activation energies were 427.095 kJ·mol^(-1)in theα+βphase region and 205.451 kJ·mol^(-1)in theβphase region,*** the basis of dynamic materials model,the processing map is generated,which shows that the highest peak efficiency of power dissipation of 56%occurs at about 1050℃/0.01 s^(-1).It can be found in the processing maps that the strain had significant effect on the peak region of power dissipation efficiency of Ti-6Al-4V-0.5Ni-0.5Nb ***,optimized hot working regions were investigated and validated through microstructure *** optimum thermo mechanical process condition for hot working of Ti-6Al-4V-0.5Ni-0.5Nb titanium alloy was suggested to be in the temperature range of 950-1000℃with a strain rate of 0.01-0.1 s^(-1).

关键词： titanium alloy hot deformation processing map dynamic recrystallization

Cardiotoxicity induced by fluoropyrimidine drugs in the treatment of gastrointestinal tumors

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 251-254页

作者： Mo-Wei Kong Feng-Di Sun Zhen-Ying Pei Li Xu ze-Bi Wang Yan Chen Shu-Qing tang Ting-Fang Yang Guo-Xiang He Department of Cardiology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina Department of Oncology Guiqian International General HospitalGuiyang 550018Guizhou ProvinceChina

In this editorial,we review the article published in World J Gastrointest Oncol 2019,11:*** specifically focus on the occurrence,clinical characteristics,and risk factors of fluoropyrimidine drug-related cardiotoxicity in patients with gastrointestinal *** significant advancements in diagnostic and therapeutic techniques that have reduced mortality rates associated with digestive system tumors,the incidence and mortality rates of treatment-related car-diotoxicity have been increasing,severely impacting the survival and prognosis of cancer *** drugs are widely used as antimetabolites in the treatment of malignant tumors,including gastrointestinal tumors,and they represent the second largest class of drugs associated with ***,there is often a lack of awareness or understanding regarding their cardiotoxic effects and associated risks.

关键词： Cardiotoxicity Gastrointestinal tumors Risk factors Fluoropyrimidine Chest pain

Establishment of predictive models and determinants of preoperative gastric retention in endoscopic retrograde cholangiopancreatography

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2574-2582页

作者： Ying Jia Hao-jun Wu tang Li Jia-Bin Liu Ling Fang Zi-Ming Liu Department of Thyroid Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Division of Biliary Tract Surgery Department of General SurgeryWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Division of General Surgery West China Hospital-Chengdu Shangjin NanfuWest China HospitalChengdu 611730Sichuan ProvinceChina

BACKGROUND Study on influencing factors of gastric retention before endoscopic retrograde cholangiopancreatography(ERCP)background:With the wide application of ERCP,the risk of preoperative gastric retention affects the smooth progress of the *** study found that female,biliary and pancreatic malignant tumor,digestive tract obstruction and other factors are closely related to gastric retention,so the establishment of predictive model is very important to reduce the risk of *** A retrospective analysis was conducted on 190 patients admitted to our hospital for ERCP preparation between January 2020 and February *** baseline clinical data were collected using an electronic medical record *** were randomly matched in a 1:4 ratio with data from 190 patients during the same period to establish a validation group(n=38)and a modeling group(n=152).Patients in the modeling group were divided into the gastric retention group(n=52)and non-gastric retention group(n=100)based on whether gastric retention occurred *** data of patients in the validation group and identify factors influencing preoperative gastric retention in ERCP patients.A predictive model for preoperative gastric retention in ERCP patients was constructed,and calibration curves were used for *** receiver operating characteristic(ROC)curve was analyzed to evaluate the predictive value of the *** We found no statistically significant difference in general data between the validation group and modeling group(P>0.05).The comparison of age,body mass index,hypertension,and diabetes between the two groups showed no statistically significant difference(P>0.05).However,we noted statistically significant differences in gender,primary disease,jaundice,opioid use,and gastrointestinal obstruction between the two groups(P<0.05).Mul-tivariate logistic regression analysis showed that gender,primary disease,jaundice,opioid use,and gastrointestina

关键词： Cholangiopancreatography Gastric retention Influencing factors Predictive model Endoscope

Nuclear charge radius predictions by kernel ridge regression with odd-even effects

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Nuclear Science and Techniques 2024年第2期35卷 94-102页

作者： Lu tang Zhen-Hua Zhang Mathematics and Physics Department North China Electric Power UniversityBeijing 102206China Hebei Key Laboratory of Physics and Energy Technology North China Electric Power UniversityBaoding 071000China

The extended kernel ridge regression(EKRR)method with odd-even effects was adopted to improve the description of the nuclear charge radius using five commonly used nuclear *** are:(i)the isospin-dependent A^(1∕3) formula,(ii)relativistic continuum Hartree-Bogoliubov(RCHB)theory,(iii)Hartree-Fock-Bogoliubov(HFB)model HFB25,(iv)the Weizsacker-Skyrme(WS)model WS*,and(v)HFB25**** the last two models,the charge radii were calculated using a five-parameter formula with the nuclear shell corrections and deformations obtained from the WS and HFB25 models,*** each model,the resultant root-mean-square deviation for the 1014 nuclei with proton number Z≥8 can be significantly reduced to 0.009-0.013 fm after considering the modification with the EKRR *** best among them was the RCHB model,with a root-mean-square deviation of 0.0092 *** extrapolation abilities of the KRR and EKRR methods for the neutron-rich region were examined,and it was found that after considering the odd-even effects,the extrapolation power was improved compared with that of the original KRR *** strong odd-even staggering of nuclear charge radii of Ca and Cu isotopes and the abrupt kinks across the neutron N=126 and 82 shell closures were also calculated and could be reproduced quite well by calculations using the EKRR method.

关键词： Nuclear charge radius Machine learning Kernel ridge regression method

Controlled synthesis of one-dimensional segmented heteronanostructures

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Science China Materials 2024年第8期67卷 2715-2716页

作者： Zhiyong tang CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China

Telluride materials possess distinctive advantages,including the high theoretical volume capacity and electrical conductivity,rendering them promising candidates for a range of energy storage and optoelectronic applications[1].Heterogeneous compositions and interfaces in heteronanostructures have significant implications on the electron transport,magnetic coupling,and phonon scattering,thereby promoting the performances in photocatalysis,and thermoelectrics[2].

关键词： synthesis rendering thereby

A supramolecular self-assembly material based on cucurbituril and cationic TPE as ultra-sensitive probe of energetic pentazolate salts

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Defence Technology（防务技术） 2024年第5期35卷 69-76页

作者： Boan tang Jingxiang Zhong Shutao Wang Shiyu Zhou Yongxing tang Wei Huang School of Chemistry and Chemical Engineering Nanjing University of Science and TechnologyNanjing 210094China

The successful synthesis of the pentazolate anion(cyclo-N-5)has been a great breakthrough in the field of energetic ***,the detection methods for these energetic materials based on the pentazolate anion are quite ***,two fluorescent probes for cyclo-N-5anion were *** 1(TPE2N)was synthesized with a tetraphenylethylene functionalized by two cationic groups which can generate strong electrostatic interactions with pentazolate anion and result in specific fluorescent *** 2 was designed based on sensor 1 and supramolecular cucurbit[7]uril(CB[7]).The unique structural features of CB[7]provide sites for the interaction between the cations and N-5anion in its cavity,which would generate a platform for the detection and enhance the recognition *** titration calorimetry(ITC)experiment and fluorescence titration experiment indicate the binding molar ratio between sensor 1 with CB[7]is 1:*** sensors display typical aggregation-induced emission(AIE)features and good *** sensors demonstrate excellent sensitivity to pentazole hydrazine salt with high enhancement constant(sensor 1:1.34×10^(6);sensor 2:3.78×10^(6))and low limit of detection(LOD:sensor 1=4.33μM;sensor 2=1.54μM).The formation of an AIE-based supramolecular sensor effectively improves the sensitivity to *** addition,the probes also have good selectivity of N-5anion *** research would shed some light on the design of novel fluorescent sensors to detect pentazolate-based molecules and provides an example of supramolecular chemistry combined with fluorescent probes.

关键词： Pentazolate anion Explosives detection Aggregation-induced emission(AIE) Host-guest interaction

Flexible and Robust Functionalized Boron Nitride/Poly(p‑Phenylene Benzobisoxazole)Nanocomposite Paper with High Thermal Conductivity and Outstanding Electrical Insulation

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Nano-Micro Letters 2024年第2期16卷 423-437页

作者： Lin tang Kunpeng Ruan Xi Liu Yusheng tang Yali Zhang junwei Gu Chongqing Key Laboratory of Green Synthesis and Applications College of ChemistryChongqing Normal UniversityChongqing 401331People’s Republic of China Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an 710072People’s Republic of China

With the rapid development of 5G information technology,thermal conductivity/dissipation problems of highly integrated electronic devices and electrical equipment are becoming *** this work,“high-temperature solid-phase&diazonium salt decomposition”method is carried out to prepare benzidine-functionalized boron nitride(m-BN).Subsequently,m-BN/poly(pphenylene benzobisoxazole)nanofiber(PNF)nanocomposite paper with nacremimetic layered structures is prepared via sol–gel film transformation *** obtained m-BN/PNF nanocomposite paper with 50 wt%m-BN presents excellent thermal conductivity,incredible electrical insulation,outstanding mechanical properties and thermal stability,due to the construction of extensive hydrogen bonds andπ–πinteractions between m-BN and PNF,and stable nacre-mimetic layered ***λ∥andλ_(⊥)are 9.68 and 0.84 W m^(-1)K^(-1),and the volume resistivity and breakdown strength are as high as 2.3×10^(15)Ωcm and 324.2 kV mm^(-1),***,it also presents extremely high tensile strength of 193.6 MPa and thermal decomposition temperature of 640°C,showing a broad application prospect in high-end thermal management fields such as electronic devices and electrical equipment.

关键词： Poly(p-phenylene-2,6-benzobisoxazole)nanofiber Boron nitride Thermal conductivity Electrical insulation

ACTN1 promotes malignant progression in cutaneous squamous cell carcinoma by downregulating the p53 signaling pathway

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中华医学杂志(英文版) 2024年第14期137卷 1759-1761页

作者： Yuan Tao Lu Xiaohong Jiang Jiahui Chen Nan tang Biao He Caifeng Liu Wenbei Wang jun Ci Chao Department of Dermatology Yijishan Hospital the First Affiliated Hospital of Wannan Medical College Wuhu Anhui China

To the Editor: Cutaneous squamous cell carcinoma (CSCC) originates from the keratinocytes of the epidermal layer and (or) its associated appendages, manifesting as a rapidly proliferating, highly destructive malignancy, with almost 20,000 cases occurring in China in 2022. The pathogenesis of CSCC is complex, but recent studies have made significant progress. Our previous research identified eight proteins, including actinin alpha 1 (ACTN1), tenascin C (TNC), fascin actin-bundling protein 1 (FSCN1), serpin family B member 1 (SERPINB1), ras-related protein 31 (RAB31), collagen type III alpha 1 chain (COL3A1), collagen type I alpha 1 chain (COL1A1), and cluster of differentiation 36 (CD36), which are markedly linked to CSCC invasion and metastasis. Besides, our subsequent assays also revealed the elevated serum level of ACTN1 in CSCC patients, which correlated with tumor cell differentiation, invasion depth, and primary tumor diameter. This underscores the potentially pivotal role of ACTN1 in CSCC pathogenesis. This study aimed to further investigate the role of ACTN1 in the pathogenesis of CSCC.

关键词： CANCER STAT3

Establishment and validation of a predictive model for peripherally inserted central catheter-related thrombosis in patients with liver cancer

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2221-2231页

作者： Xiao-Fei Chen Hao-jun Wu tang Li Jia-Bin Liu Wen-Jie Zhou Qiang Guo Department of Thyroid Surgery West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina The Second Department of General Surgery Chengdu Shangjinnanfu HospitalWest China Hospital of Sichuan UniversityChengdu 611730Sichuan ProvinceChina Department of Biliary Surgery West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Hepatobiliary and Pancreatic Surgery Chengdu Shangjinnanfu HospitalWest China Hospital of Sichuan UniversityChengdu 611730Sichuan ProvinceChina Department of Vascular Surgery West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Peripherally inserted central catheters(PICCs)are commonly used in hospitalized patients with liver cancer for the administration of chemotherapy,nutrition,and other ***,PICC-related thrombosis is a serious complication that can lead to morbidity and mortality in this patient *** risk factors have been identified for the development of PICC-related thrombosis,including cancer type,stage,comorbidities,and catheter *** these risk factors and developing a predictive model can help healthcare providers identify high-risk patients and implement preventive measures to reduce the incidence of *** To analyze the influencing factors of PICC-related thrombosis in hospitalized patients with liver cancer,construct a predictive model,and validate *** Clinical data of hospitalized patients with liver cancer admitted from January 2020 to December 2023 were ***-five cases of PICC-related thrombosis in hospitalized patients with liver cancer were collected,and 220 patients who underwent PICC placement during the same period but did not develop PICC-related thrombosis were randomly selected as controls.A total of 255 samples were collected and used as the training set,and 77 cases were collected as the validation set in a 7:3 *** patient information,case data,catheterization data,coagulation indicators,and Autar Thrombosis Risk Assessment Scale scores were *** and multivariate unconditional logistic regression analyses were performed on relevant factors,and the value of combined indicators in predicting PICC-related thrombosis in hospitalized patients with liver cancer was evaluated using receiver operating characteristic(ROC)curve *** Univariate analysis showed statistically significant differences(P<0.05)in age,sex,Karnofsky performance status score(KPS),bedridden time,activities of daily living impairment,parenteral nutrition,catheter duration,d

关键词： Liver cancer Peripherally inserted central catheters Thrombosis Model Verify