检索结果-南通市图书馆

MXene Hybridized Polymer with Enhanced Electromagnetic Energy Harvest for Sensitized Microwave Actuation and Self‑Powered Motion Sensing

引用

Nano-Micro Letters 2025年第3期17卷 265-279页

作者： Yu‑ze wang Yu‑Chang wang Ting‑Ting Liu Quan‑Liang Zhao Chen‑Sha Li Mao‑Sheng Cao School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081People’s Republic of China School of Materials Science and Engineering Peking UniversityBeijing 100871People’s Republic of China School of Mechanical and Material Engineering North China University of TechnologyBeijing 100144People’s Republic of China Key Laboratory of Functional Inorganic Material Chemistry Ministry of Education of the People’s Republic of ChinaHeilongjiang UniversityHarbin 150080People’s Republic of China

Polymeric microwave actuators combining tissue-like softness with programmablemicrowave-responsive deformation hold great promise for mobile intelligentdevices and bionic soft robots. However, their application is challenged by restricted electromagneticsensitivity and intricate sensing coupling. In this study, a sensitized polymericmicrowave actuator is fabricated by hybridizing a liquid crystal polymer with Ti3C2Tx(MXene). Compared to the initial counterpart, the hybrid polymer exhibits unique spacechargepolarization and interfacial polarization, resulting in significant improvements of230% in the dielectric loss factor and 830% in the apparent efficiency of electromagneticenergy harvest. The sensitized microwave actuation demonstrates as the shortenedresponse time of nearly 10 s, which is merely 13% of that for the initial shape memory polymer. Moreover, the ultra-low content of MXene (upto 0.15 wt%) benefits for maintaining the actuation potential of the hybrid polymer. An innovative self-powered sensing prototype that combinesdriving and piezoelectric polymers is developed, which generates real-time electric potential feedback (open-circuit potential of ~ 3 mV) duringactuation. The polarization-dominant energy conversion mechanism observed in the MXene-polymer hybrid structure furnishes a new approachfor developing efficient electromagnetic dissipative structures and shows potential for advancing polymeric electromagnetic intelligent devices.

关键词： Microwave absorption Electromagnetic response Energy harvest Self-sensing Soft actuator

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Strength through unity: Alkaline phosphatase-responsive AIEgen nanoprobe for aggregation-enhanced multi-mode imaging and photothermal therapy of metastatic prostate cancer

引用

Chinese Chemical Letters 2025年第2期36卷 289-296页

作者： ze wang Hao Liang Annan Liu Xingchen Li Lin Guan Lei Li Liang He Andrew K.Whittaker Bai Yang Quan Lin State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University Department of Endocrinology Lequn Branch the First Hospital of Jilin University Department of Urology the First Hospital of Jilin University Australian Institute for Bioengineering and Nanotechnology the University of Queensland

Prostate cancer(PCa) is characterized by high incidence and propensity for easy metastasis, presenting significant challenges in clinical diagnosis and treatment. Tumor microenvironment(TME)-responsive nanomaterials provide a promising prospect for imaging-guided precision therapy. Considering that tumor-derived alkaline phosphatase(ALP) is over-expressed in metastatic PCa, it makes a great chance to develop a theranostics system with ALP responsive in the TME. Herein, an ALP-responsive aggregationinduced emission luminogens(AIEgens) nanoprobe AMNF self-assembly was designed for enhancing the diagnosis and treatment of metastatic PCa. The nanoprobe exhibited self-aggregation in the presence of ALP resulted in aggregation-induced fluorescence, and enhanced accumulation and prolonged retention period at the tumor site. In terms of detection, the fluorescence(FL)/computed tomography(CT)/magnetic resonance(MR) multi-mode imaging effect of nanoprobe was significantly improved post-aggregation, enabling precise diagnosis through the amalgamation of multiple imaging modes. Enhanced CT/MR imaging can achieve assist preoperative tumor diagnosis, and enhanced FL imaging technology can achieve “intraoperative visual navigation”, showing its potential application value in clinical tumor detection and surgical guidance. In terms of treatment, AMNF showed strong absorption in the near infrared region after aggregation, which improved the photothermal treatment effect. Overall, our work developed an effective aggregation-enhanced theranostic strategy for ALP-related cancers.

关键词： AIE ALP responsive Enhanced multi-mode imaging Enhanced photothermal therapy Prostate cancer

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

In vivo self-assembled bispecific fluorescence probe for early detection of bladder cancer and metastasis

引用

Science Bulletin 2025年第3期70卷 407-418页

作者： Da-Yong Hou Ni-Yuan Zhang Peng Zhang Xiang-Peng Li Jiong-Cheng Wu Mei-Yu Lv Zhi-Jia wang Xing-Jie Hu Jian-Xiao Liang Hong-Lei wang Yue-ze wang Hui-Hui You Hong-Wei An Hao wang Wanhai Xu NHC Key Laboratory of Molecular Probe and Targeted Theranostics Heilongjiang Key Laboratory of Scientific Research in UrologyHarbin Medical UniversityHarbin 150001China Department of PET-CT/MRI Harbin Medical University Cancer HospitalHarbin 150001China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology(NCNST)Beijing 100190China

Tumor metastasis accounts for over 90%of tumor-related deaths,prompting the development of fluorescently labeled tumor-specific molecular imaging agents for differentiating tumors from normal ***,early detection of metastasis lesions by tracking tumor markers alone has proven to be ***,we reported a glycopeptide-based bispecific fluorescence probe(bsProbe)for earlier detection of bladder cancer and *** simultaneously recognition(tumor&tumor microenvironment)and in vivo self-assembly,the tumor accumulation of bsProbe(12.3%ID/g)was obviously increased by∼6 fold compared with that in CXCR4 specific fluorescence probe(sProbe),indicating the obvious advantages of bsProbe over existing tumor metastasis detection ***,bsProbe substantially broadens the tumor diagnosis window and enhances the detection signal to noise ratio(SNR:approximately 9.5),permitting early diagnosis of lung micro-metastasis(∼1 mm),precise identifying of tumor boundaries and micro-tumors in orthotopic tumor *** importantly,bsProbe was demonstrated to distinguish malignant from benign specimen with a specificity of 90.48%and sensitivity of 92.22%in 195 clinical specimens of bladder cancer *** together,this novel synergetic targeting(CD206×CXCR4)strategy provides an attractive method for earlier detection of bladder cancer and metastasis,which might be further extended to the imaging-guided surgery of clinical invisible tumors.

关键词： Self-assembly Peptide Nanomaterial Fluorescence imaging Bladder cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimization-based conformal path planning for in situ bioprinting during complex skin defect repair

引用

Bio-Design and Manufacturing 2025年第1期8卷 1-19,I0001页

作者： Wenxiang Zhao Chuxiong Hu Yunan wang Shize Lin ze wang Tao Xu State Key Laboratory of Tribology in Advanced Equipment Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China Beijing Key Laboratory of Precision and Ultra-Precision Manufacturing Equipment and Control Tsinghua UniversityBeijing 100084China Center for Bio-intelligent Manufacturing and Living Matter Bioprinting Research Institute of Tsinghua University in ShenzhenTsinghua UniversityShenzhen 518057China

The global demand for effective skin injury treatments has prompted the exploration of tissue engineering *** three-dimensional(3D)bioprinting has shown promise,challenges persist with respect to achieving timely and compatible solutions to treat diverse skin *** situ bioprinting has emerged as a key new technology,since it reduces risks during the implantation of printed scaffolds and demonstrates superior therapeutic ***,maintaining printing fidelity during in situ bioprinting remains a critical challenge,particularly with respect to model layering and path *** study proposes a novel optimization-based conformal path planning strategy for in situ bioprinting-based repair of complex skin *** strategy employs constrained optimization to identify optimal waypoints on a point cloud-approximated curved surface,thereby ensuring a high degree of similarity between predesigned planar and surface-mapped 3D ***,this method is applicable for skin wound treatments,since it generates 3D-equidistant zigzag curves along surface tangents and enables multi-layer conformal path planning to facilitate the treatment of volumetric ***,the proposed algorithm was found to be a feasible and effective treatment in a murine back injury model as well as in other complex models,thereby showcasing its potential to guide in situ bioprinting,enhance bioprinting fidelity,and facilitate improvement of clinical outcomes.

关键词： In situ bioprinting Path planning Robot control Skin injury repair

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

朱英诞谐诗观及其实践

引用

西北大学学报(哲学社会科学版) 2025年第1期55卷 130-141页

作者：王泽龙温琳舒华中师范大学文学院湖北武汉430079

“谐”是中国文学中重要的审美范畴,广泛存在于文学创作中。朱英诞的诗与“谐”存在不解之缘。朱英诞谐诗观,推重真实平淡的诗质,寓庄于谐的诗意,谐隐结合的诗语。依据谐诗的成分构成、情感色彩与书写内容,朱英诞谐诗呈现为典型性谐诗... 详细信息

“谐”是中国文学中重要的审美范畴,广泛存在于文学创作中。朱英诞的诗与“谐”存在不解之缘。朱英诞谐诗观,推重真实平淡的诗质,寓庄于谐的诗意,谐隐结合的诗语。依据谐诗的成分构成、情感色彩与书写内容,朱英诞谐诗呈现为典型性谐诗与渗透性谐诗、谐谑性谐诗与讽刺性谐诗、梦幻性谐诗与现实性谐诗。朱英诞谐诗实践表现出的特质为:反常合道、曲径通幽的诗思建构,雅俗结合、新鲜陌生的诗语选取,以奇取胜、以怪致笑的修辞手段。朱英诞将“谐”从一种乐观的人生态度转化为趣味性的诗学营养,其诗呈现出庄谐杂陈、奇趣盎然的独特美学风貌。

关键词：朱英诞诗歌谐诗观谐隐结合乖讹消解

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Wnt信号通路在近视发病中作用及机制的研究进展

引用

国际眼科杂志 2025年第1期25卷 99-103页

作者：王泽颉瑞萍刘雪甘肃中医药大学中医临床学院甘肃省兰州市730000 甘肃中医药大学附属医院眼科甘肃省兰州市730020

近视是全球范围内日益严重的公共卫生问题,其发病机制复杂,涉及多种信号通路和基因的相互作用。Wnt信号通路在细胞增殖、分化和凋亡,以及组织重塑等生物学过程中发挥着重要作用,近年来其在近视发病中的作用逐渐受到关注。研究表明,Wnt... 详细信息

近视是全球范围内日益严重的公共卫生问题,其发病机制复杂,涉及多种信号通路和基因的相互作用。Wnt信号通路在细胞增殖、分化和凋亡,以及组织重塑等生物学过程中发挥着重要作用,近年来其在近视发病中的作用逐渐受到关注。研究表明,Wnt信号通路通过调节视网膜细胞(包括RPE细胞和ipRGCs)的增殖、分化和凋亡,以及巩膜成纤维细胞的增殖和细胞外基质成分(如Ⅰ型胶原蛋白)的表达,进而影响巩膜重塑和眼轴增长,最终影响近视的发生发展。文章总结了不同眼组织(视网膜和巩膜)中Wnt信号通路在近视发生发展中的作用并在此基础上对基于Wnt信号通路的近视防治策略进行了探讨,以期为近视相关机制研究及临床治疗提供思路。

关键词：近视 Wnt信号通路发病机制巩膜视网膜细胞

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

蛹虫草水提物影响人胃癌细胞BGC-823不同RCD通路的转录组分析

引用

食品工业科技 2025年第4期46卷 10-18页

作者：崔明琦于凯雯宋扬徐方旭王升厚王泽沈阳师范大学生命科学学院辽宁沈阳110034 辽宁省功能性蛹虫草重点实验室辽宁沈阳110034 沈阳师范大学实验教学中心辽宁沈阳110034

目的:基于转录组测序技术,分析预测蛹虫草(XG)水提物影响人胃癌细胞BGC-823生长活性的主要调节性细胞死亡(Regulated Cell Death,RCD)信号通路。方法:MTT法测定XG水提物对胃癌细胞增殖能力的影响,转录组测序分析显著差异基因及其京都基... 详细信息

目的:基于转录组测序技术,分析预测蛹虫草(XG)水提物影响人胃癌细胞BGC-823生长活性的主要调节性细胞死亡(Regulated Cell Death,RCD)信号通路。方法:MTT法测定XG水提物对胃癌细胞增殖能力的影响,转录组测序分析显著差异基因及其京都基因与基因组百科全书(Kyoto Encyclopedia of Genes and Genomes,KEGG)通路富集情况,获得凋亡、自噬、坏死性凋亡及铁死亡信号通路的hub基因(10个)。通过激光共聚焦、流式细胞术、实时荧光定量PCR(qRT-PCR)进一步验证XG水提物对胃癌细胞凋亡的诱导情况。结果:XG水提物对人胃癌细胞BGC-823生长活性的抑制作用具有剂量依赖特征。转录组测序共筛选到5885个差异表达基因,并在凋亡(P=0.001)及自噬(P=0.008)信号通路存在显著性富集,除铁死亡外,其它信号通路的hub基因的表达量均被显著性抑制,包括caspase依赖性凋亡信号通路的关键因子CASP3、CASP9、CASP7和APAF1,自噬小体形成相关的基因ULK1、ULK2、UVRAG、Atg14及Atg5。细胞学检测结果显示,胃癌细胞经XG水提物处理后呈典型的凋亡形态学特征,早期凋亡率为24.8%,细胞周期阻滞于G2/M期。qRT-PCR检测显示,BCL2、BCL2L1、CASP3、CASP9及XIAP的表达受到显著抑制(P<0.01),ENDOG和AIF表达量显著上调(P<0.01),与转录组测序结果一致。结论:蛹虫草主要通过caspase非依赖性线粒体凋亡途径抑制人胃癌细胞BGC-823的生长活性,同时可以影响自噬等信号通路的激活,为蛹虫草在功能性食品的开发提供理论支持。

关键词：蛹虫草凋亡自噬坏死性凋亡铁死亡

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hepatic hemangiomas mimicking gastrointestinal stromal tumors: A case report

引用

World Journal of Clinical Cases 2025年第11期13卷 66-71页

作者： Ji-ze wang Hao Chen Department of Surgical Oncology Oncology CenterLanzhou University Second HospitalLanzhou 730030Gansu ProvinceChina

BACKGROUND Hepatic hemangiomas can be challenging to diagnose,particularly when they present with atypical features that mimic other conditions,such as gastrointestinal stromal tumors(GISTs).This case highlights the diagnostic difficulties encountered when imaging subepithelial lesions,especially when conventional methods such as computed tomography(CT)and endoscopic ultrasound(EUS)are *** SUMMARY A 44-year-old woman presented with intermittent abdominal distension and heartburn for three *** medical history included iron deficiency anemia,menorrhagia,and previous *** week prior to admission,an endoscopy suggested a bulging gastric fundus,which was likely a GIST,along with chronic nonatrophic gastritis and bile *** and EUS revealed nodules in the gastric fundus,which were initially considered benign tumors with a differential diagnosis of stromal tumor or *** surgery,unexpected lesions were found in the liver pressing against the gastric fundus,leading to laparoscopic liver *** pathology confirmed the diagnosis of hepatic cavernous *** patient recovered well and was discharged five days later,with normal follow-up results at three *** This case underscores the challenges in the preoperative diagnosis of GISTs,particularly the limitations of the use of CT and EUS for the evaluation of subepithelial *** CT is the primary tool for visualizing abdominal tumors,it is difficult to detect smaller lesions and assess the layers of the gastrointestinal wall on *** is recommended for the evaluation of nodules smaller than 2 cm and is useful for distinguishing GISTs from other lesions;however,its accuracy with regard to the differential diagnosis is relatively *** this case,the gastric distension observed on imaging led to the compression of a liver tumor against the stomach,resulting in the misinterpretation of the tumor as a gastric wall lesion.

关键词： Hepatic hemangioma Gastrointestinal stromal tumors Left lobe tumor Subepithelial lesions Extragastric lesions Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nonreciprocal Head-on Collision Between Two Nonlinear Solitary Waves in Granular Metamaterials with an Interface

引用

Acta Mechanica Solida Sinica 2022年第1期35卷 139-151页

作者： Qi Lu Yi-ze wang Department of Mechanics Tianjin UniversityTianjin 300350China

In this work,the head-on collision and transmission with nonreciprocal properties of opposite propagating solitary waves are studied,in which the interface between different granular chains is *** to the discontinuity of two periodic granular systems,the transmitted and reflected solitary waves are *** head-on collision appears at the interface and the reductive perturbation method is applied to derive the generated solitary *** to the derivation and numerical simulation,we can find that the transmitted and reflected solitary waves can propagate with the same speed when they locate at the same ***,the influences of both the arrangement and prestress are *** is found that the amplitude and velocity of solitary waves become larger because of a bigger prestress,which result in the nonreciprocal collision and transmission in the granular mechanical *** study is expected to be helpful for the design and application of elastic wave metamaterials and mechanical diodes with nonlinear solitary waves.

关键词： Granular metamaterial Nonlinear solitary waves Head-on collision Interface Nonreciprocal properties

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Small Solutions of Quadratic Equations with Prime Variables in Arithmetic Progressions

引用

Acta Mathematica Sinica,English Series 2009年第2期25卷 299-320页

作者： Tian ze wang School of Mathematics and Information Sciences He'nan University Kaifeng 475001 P. R. China School of Mathematics and Information Sciences North China University of Water Conservancy and Electric Power Zhengzhou 450011 P. R. China

A necessary and sufficient solvable condition for diagonal quadratic equation with prime variables in arithmetic progressions is given, and the best qualitative bound for small solutions of the equation is obtained,

关键词： quadratic equation prime variable small solution arithmetic progression

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：