检索结果-南通市图书馆

Congenital Hernia of the Diaphragmatic Dome with Neonatal Revelation, Experience from the Neonatology and Neonatal Intensive Care Unit at the University Hospital Center of Oujda

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Pediatrics 2024年第5期14卷 790-799页

作者： Addou Bebana Anass Ayyad Mohammed ec-Chebab Sahar Messaoudi Rim Amrani Pediatrics/Residency Mohammed VI University Hospital Oujda Morocco Department of Neonatology and Neonatal Intensive Care Unit Mohammed VI University Hospital Medical School Mohammed First University Oujda Morocco The Maternal-Child & Mental Health Research Laboratory Oujda Morocco

Congenital hernia of the diaphragmatic dome (CHDD) is an embryonic malformation in which all or part of the diaphragmatic dome fails to develop properly. In the majority of cases (80% to 90%), this malformation affects the left posterolateral part of the diaphragm, while in 10% to 15% of cases it affects the right. Bilateral cases are extremely rare, accounting for less than 1% of cases. This malformation is estimated to occur at a frequency of around 1 in 3500 births, with a male predominance. The diaphragmatic defect causes the abdominal organs to rise into the thoracic cavity during critical phases of lung development. These anomalies result in bilateral pulmonary hypoplasia, a reduced number of pulmonary vessels, and pulmonary arterial hypertension (PAH). The combination of these anatomical and functional anomalies, in varying degrees, explains the wide variability of symptoms at birth. Diagnosis is usually made prenatally by ultrasound, which enables severe forms of the disease to be detected and appropriate management initiated. The prognosis remains generally grave, with a neonatal mortality rate of between 30% and 60% depending on the study, and around half of all children will have long-term sequelae.

关键词： Congenital Diaphragmatic Hernia Prenatal Diagnosis Pulmonary Hypoplasia Pulmonary Hypertension Medical-Surgical Treatment

On the Nature of the P-Wave Velocity Gradient in the Inner Core beneath Central America

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Earth Science 2013年第5期24卷 699-705页

作者： Hrvoje tkali Thomas Bodin Mallory Young Malcolm Sambridge Research School of Earth Sciences the Australian National University Berkeley Seismological Laboratory University of California at Berkeley

We conduct an experiment to investigate whether linearity in the observed velocity gradient in the volume of the inner core sampled by the PKP ray paths beneath Central America is a robust approximation. Instead of solving an optimization problem, we approach it within the Bayesian inference. This is an ensemble approach, where model specification is relaxed so that in- stead of only one solution, groups of reasonable models are acceptable. Furthermore, in transdimen- sional Bayesian inference used here, the number of basis functions needed to model observations is by itself an unknown. Our modeling reveals that in the ensemble of models, the most likely are those containing only 2 nodes （linear trend）. Thus our result justifies the assumption used for the deter- mination of inner core rotation with respect to the rest of the mantle that the observed gradient is constant in its nature （linear）. Recent observations in seismology suggest that it is likely that the spa- tial variability in elastic parameters is a widespread phenomenon in the inner core. Future array observations will further constrain spatial extent and magnitude of velocity changes and show whether there is a significant difference between these observations in the two quasi-hemispheres of the inner core.

关键词： solid earth physics deep geophysics.

On Ductile Damage Modelling of Heterogeneous Material Using Second-Order Homogenization Approach

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2021年第3期126卷 915-934页

作者： Jurica Soric Tomislav Lesicar zdenko Tonkovic Faculty of Mechanical Engineering and Naval Architecture University of ZagrebZagreb10000Croatia

The paper deals with the numerical modelling of ductile damage responses in heterogeneous materials using the classical second-order homogenization *** scale transition methodology in the multiscale framework is *** structure at the macrolevel is discretized by the triangular C^(1) finite elements obeying nonlocal continuum theory,while the discretization of microstructural volume element at the microscale is conducted by means of the mixed type quadrilateral finite element with the nonlocal equivalent plastic strain as an additional nodal *** ductile damage evolution at the microlevel is modelled by using the gradient enhanced *** macrolevel softening is governed by two criterions expressed by the increase in homogenized damage variable and the threshold of the local equivalent *** softening at each material point at the macrolevel is detected by the critical value of the homogenized damage,where homogenization of the damage variable is performed onlywithin softening *** to the nonlocal continuumtheory applied,a realistic softening behaviour is demonstrated after the damage initiation,compared to the widely used first-order homogenization *** algorithms derived have been embedded into the finite element code ABAQUS by means of the user subroutines and verified on the standard benchmark *** damage evolution at both microlevel and macrolevel has been demonstrated.

关键词： Ductile damage second-order homogenization multiscale approach C1 finite element

Pathophysiology profile-an outcome of international survey:General pathophysiology and integrative clinical reasoning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国病理生理杂志 2009年第11期25卷 2243-2244页

作者： zdenko Kovac Department of Pathophysiology Medical School University of Zagreb

Short international survey has been done among the members of International Society for Pathophysiology. 42 to 46 valid answers,which came from 22 countries,were accumulated and analyzed. The average of teaching hours of pathophysiology course in various curricula is 146 out of 5 788 total teaching hours of medical curricula (lecture 58,seminars 44,practical 52). Average teaching materials consist of 863 pages of obligatory texts and 1 225 pages of recommended materials. An estimated students' 'study time' for successful mastering of the exam is 164 hours (along with 146 contact teaching/learning hours). A survey concerning an educational profile of the pathophysiologist (A),contents of teaching (B),a selective advantage of pathophysiology teaching (C) and personal advise of pathophysiologists with respect of educational curricula (D) have been quantified by number 1 through 10; one being the weakest and ten being the strongest. Each of the survey features (A through D) was described in advance by 8 different statements,among which participants gave their 'intensity of support' using numerical values 1-10. The outcome indicates that the best profile of pathophysiologists' education scheme is that with 'MD + PhD + postdoctoral training + any residency' (score 8.57) and weakest profile 'PhD in the field of molecular biology' (4.93). The strongest 'power and relevance of pathophysiology' has been given to type of the subject which '…represents an integrative frame of reference describing common principles of disease' (8.59),whereas the weakest to the 'It leads to the evidence based practice and reduces medical costs' (7.65). With reference to the teaching contents the highest rank was given to 'Symptoms/signs/dysfunctions correlations with molecular nature of etiopathogenetic processes' (8.67),whereas the weakest points were given to 'quantitative aspects of etiopathogenetic processes' (6.60). When pathophysiologists were asked to give 'an educated

关键词：病理生理学国际调查配置文件推理临床教学时数学习时间课程

A Multiscale Method for Damage Analysis of Quasi-Brittle Heterogeneous Materials

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2019年第7期120卷 123-156页

作者： Filip Putar Jurica Soric Tomislav Lesicar zdenko Tonkovic Faculty of Mechanical Engineering and Naval Architecture University of ZagrebIvana Lucica 5Zagreb 10000Croatia

A novel multiscale algorithm based on the higher-order continuum at both micro-and macrostructural level is proposed for the consideration of the quasi-brittle damage response of heterogeneous ***,the microlevel damage is modelled by the degradation of the homogenized stress and tangent stiffness tensors,which are then upscaled to govern the localization at the *** C^1 continuity finite element employing a modified case of Mindlin’s form II strain energy density is derived for the softening *** the authors’knowledge,the finite element discretization based on the strain gradient theory is applied for the modeling of damage evolution at the microstructural level for heterogeneous materials for the first *** advantage of the novel C1 finite element formulation in comparison with the standard finite element discretization in terms of the regularization efficiency as well as the objectivity has been *** isotropic damage law is used for the reduction of the constitutive and nonlocal material behaviour,which is necessary for the physically correct description of the localization formation in quasi-brittle *** capabilities of the derived finite element to capture the fully developed localization zones are tested on a random representative volume element(RVE)for several different loading *** employing the conventional second-order computational homogenization,the microstructural material constitutive response is averaged over the whole RVE *** order to model the loss of structural integrity when sharp localization is formed across RVE,the specific conditions which detect a completely formed localization zone are developed.A new failure criterion at the microstructural level has been *** derived finite element formulation,as well as the multiscale damage algorithm,are implemented into the finite element program *** capabilities of the presented multiscale scheme to capture the effects of the deformat

关键词： Multiscale analysis second-order computational homogenization damage,C^(1) continuity finite element quasi-brittle material

Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2019年第2期13卷 238-252页

作者： Anna Khlyustova Cédric Labay zdenko Machala Maria-Pau Ginebra Cristina Canal Biomaterials Biomechanics and Tissue Engineering GroupDepartment of Materials Science and MetallurgyUniversitat Politecnica de CatalunyaBarcelona 08019Spain Research centre in Multiscale Science and Engineering Universitat Politecnica de CatalunyaBarcelona 08019Spain Faculty of Mathematics Physics and InformaticsComenius UniversityBratislava 84248Slovakia

Reactive oxygen and nitrogen species (RONS) are among the key factors in plasma medicine. They are generated by atmospheric plasmas in biological fluids, living tissues and in a variety of liquids. This ability of plasmas to create a delicate mix of RONS in liquids has been used to design remote or indirect treatments for oncological therapy by treating biological fluids by plasmas and putting them in contact with the tumour;Documented effects include selective cancer cell toxicity, even though the exact mechanisms involved are still under investigation. However, the "right" dose for suitable therapeutical activity is crucial and still under debate. The wide variety of plasma sources hampers comparisons. This review focuses on atmospheric pressure plasma jets as the most studied plasma devices in plasma medicine and compiles the conditions employed to generate RONS in relevant liquids and the concentration ranges obtained. The concentrations of H2O2, NO2^-, NO3^- and short-lived oxygen species are compared critically to provide a useful overview for the reader.

关键词： atmospheric plasma jets liquids ROS RNS plasma-dose

Association of Psb28 and Psb27 Proteins with PSII-PSI Supercomplexes upon Exposure of Synechocystis sp. PCC 6803 to High Light

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2017年第1期10卷 62-72页

作者： Martina Beckova zdenko Gardian Jianfeng Yu Peter Konik Peter J. Nixon Josef Komenda Institute of Microbiology Center Algatech Opatovicky mlyn37981 Trebon Czech Republic Faculty of Science University of South Bohemia Branisovska 1760 37005 Ceske Budejovice Czech Republic Institute of Plant Molecular Biology Biology Centre Academy of Sciences Branisovska 3137005 Ceske Budejovice Czech Republic Sir Ernst Chain Building-Wolfson Laboratories Department of Life Sciences Imperial College London South Kensington Campus London SW7 2AZ UK

Formation of the multi-subunit oxygen-evolving photosystem II （PSII） complex involves a number of auxiliary protein factors. In this study we compared the localization and possible function of two homolo- gous PSU assembly factors, Psb28-1 and Psb28-2, from the cyanobacterium Synechocystis sp. PCC 6803. We demonstrate that FLAG-tagged Psb28-2 is present in both the monomeric PSII core complex and a PSII core complex lacking the inner antenna CP43 （RC47）, whereas Psb28-1 preferentially binds to RC47. When cells are exposed to increased irradiance, both tagged Psb28 proteins additionally associate with oligo- meric forms of PSII and with PSII-PSI supercomplexes composed of trimeric photosystem I （PSI） and two PSII monomers as deduced from electron microscopy. The presence of the Psb27 accessory protein in these complexes suggests the involvement of PSI in PSII biogenesis, possibly by photoprotecting PSII through energy spillover. Under standard culture conditions, the distribution of PSII complexes is similar in the wild type and in each of the single psb28 null mutants except for loss of RC47 in the absence of Psb28-1. In comparison with the wild type, growth of mutants lacking Psb28-1 and Psb27, but not Psb28-2, was retarded under high-light conditions and, especially, intermittent high-light/dark conditions, emphasizing the physiological importance of PSII assembly factors for light acclimation.

关键词： Psb28 proteins photosystem I and II Synechocystis

Global Distributive Justice and Education

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Philosophy Study 2016年第9期6卷 523-527页

作者： zdenko Kodelja Educational Research Institute

Global distributive justice is directly connected to the increased inequality in the world. This inequality, which includes the huge inequality of education opportunities, is usually understood as unjust. There are two main approaches to this problem： cosmopolitan and statist. Looking from the cosmopolitan point of view, this kind of injustice is related predominantly with the socio-economic relationships among the individuals on the planet. Just the opposite is the view of the so-called statists, who claim that a more just world is not a world of persons who are equal among themselves, but rather a world of nation states which are able to achieve a more just society within their borders and, consequently, a more just and egalitarian global society as well.

关键词： global justice distributive justice education political philosophy cosmopolitanism

3-位取代的三环[3.2.1.0^(3,6)]辛烷衍生物的合成

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

北京大学学报（自然科学版） 1993年第4期29卷 445-451页

作者：李季 zdenko Majerskj 北京大学化学系 Rudjer Boskovic Institute

本文报道了3-位取代的三环[3.***.1.0^(3,6)]辛烷衍生物的合成,并讨论了合成反应中所包含的区域及立体选择效应。

关键词：合成三环辛烷立体选择效应