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Use of ultrasonic transient elastography (Fibroscan) in the assessment of hepatic focal lesion stiffness

Open Journal of Gastroenterology 2013年第2期3卷 107-112页

作者： Mohamed Yousef Aisha Elsharkawy Mohammad El Beshlawy Gamal Esmat zakaria salama Department of Endemic Medicine and Hepatology Faculty of Medicine Cairo University Cairo Egypt

Background and Aim: Hepatic focal lesions differ in their tissue composition and in the degree of stiffness, so our aim was to evaluate the role of Ultrasonic Transient Elastography (Fibroscan) in the measurement of hepatic focal lesions stiffness in order to differentiate hepatocellular carcinoma (HCC) focal lesions from other non HCC focal lesions. Methods: The study was conducted on 34 patients with hepatic focal lesion(s) in the right lobe located near the liver surface and more than or equal4 cmin diameter, detected by imaging studies and diagnosed by CT and histopathology. Stiffness over the focal lesions was measured by the fibroscan. Results: The median value of stiffness was 72.5 kPa over HCC focal lesions, 17.2 kPa over lymphoma focal lesions, 6.5 kPa over metastatic focal lesions and 10.5 kPa over the sarcoidosis focal lesion. Conclusions: Hepatocellular carcinoma focal lesions are much stiffer than lymphoma, metastasis or sarcoidosis focal lesions. Fibroscan may be a useful non-invasive method in the prediction of hepatocellular carcinoma in the future.

关键词： Hepatic Focal Lesions Hepatocellular Carcinoma Fibroscan Stiffness

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Value of transabdominal bowel ultrasonography and splanchic vascular parameters in the evaluation of inflammatory bowel disease

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Open Journal of Gastroenterology 2013年第2期3卷 99-106页

作者： Manal Kamel Magdy El-Serafy Hussein Attia Hanan Abdeel-Haleem Naglaa Zayed Maha Hasab-Allah zakaria salama Endemic Medicine Department Cairo University Cairo Egypt Gastrointestinal Endoscopy Unit Faculty of Medicine Cairo University Cairo Egypt Radiology Department National Cancer Institute Cairo University Cairo Egypt

Background: Although non-specific, transabdominal bowel ultrasonography, in real time or in color Doppler;has been beneficial in evaluating the location, extent and activity of inflammatory bowel disease (IBD). Aim: To assess the potential role of bowel transabdominal bowel ultrasonography in the diagnosis and follow-up of IBD. Patients and Methods: A cohort of 30 adults histologically-proven active IBD patients;ulcerative colitis (UC) (n = 20), Crohn’s disease (CD) (n = 10) were prospectively assessed in addition to 20 non-IBD participants representing the control group. All participants underwent the full colonoscopy in addition to real time and color Doppler ultrasonography. Bowel wall thickness, peri-enteric changes, and hemodynamic changes in the portal vein and mesenteric arteries were recorded at initial enrollment and after complete remission in 10 IBD patients. Results: Bowel wall was significantly thickened in all active IBD patients with a significant decrease after disease quiescence in CD patients;p value p value

关键词： Bowel Ultrasonography-Inflammatory Bowel Disease Ulcerative Colitis Crohn’s Disease Splanchnic Vessels Doppler

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