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Research 2024年第2期2024卷 55-79页

作者： Yang Yang Lee zaini abdul halim Mohd Nadhir Ab Wahab Tarik Adnan Almohamad School of Electrical and Electronic Engineering Universiti Sains MalaysiaNibong Tebal 14300 Penang Malaysia School of Computer Sciences Universiti Sains MalaysiaGelugor11800 PenangMalaysia Electrical-Electronics Engineering Department Faculty of EngineeringKarabuk University78050 KarabukTurkiye

Stochastic computing(SC)has a substantial amount of study on application-specific integrated circuit(ASIC)design for artificial intelligence(AI)edge computing,especially the convolutional neural network(CNN)***,SC has little to no optimization on field-programmable gate array(FPGA).Scaling up the ASIC logic without FPGA-oriented designs is inefficient,while aggregating thousands of bitstreams is still challenging in the conventional *** research has reinvented several FPGA-efficient 8-bit SC CNN computing architectures,i.e.,SC multiplexer multiply-accumulate,multiply-accumulate function generator,and binary rectified linear unit,and successfully scaled and implemented a fully parallel CNN model on Kintex7 *** proposed SC hardware only compromises 0.14%accuracy compared to binary computing on the handwriting Modified National Institute of Standards and Technology classification task and achieved at least 99.72%energy saving per image feedforward and 31?more data throughput than modern *** to SC,early decision termination pushed the performance baseline exponentially with minimum accuracy loss,making SC CNN extremely lucrative for AI edge computing but limited to classification *** SC's inherent noise heavily penalizes CNN regression performance,rendering SC unsuitable for regression tasks.

关键词： hardware Highly rendering

Determination of Suspended Structure in Microhotplate Using Gradient Method

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材料科学与工程（中英文版） 2010年第11期4卷 89-93页

作者： zaini abdul halim Zarina Tardan Othman Sidek CEDEC （Collaborative pElectronic Design Excellent Center） Universiti Sains Malaysia Nibong Tebal 14300 Pulau Pinang Malaysia School of Electrical and Electronic Engineering Universiti Sains Malaysia Nibong Tebal 14300 Pulau Pinang Malaysia

A review on promising phytochemical, nutritional and glycemic control studies on Moringa oleifera Lam. in tropical and sub-tropical regions

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Asian Pacific Journal of Tropical Biomedicine 2016年第10期6卷 896-902页

作者： Hafiz Irfan Muhammad Mohd zaini Asmawi Nurzalina abdul Karim Khan Discipline of Pharmacology School of Pharmaceutical Sciences Universiti Sains Malaysia Department of Pharmacology Faculty of Pharmacy University of Sargodha Discipline of Pharmaceutical Technology School of Pharmaceutical Sciences Universiti Sains Malaysia

Plants have provided sources to find novel compounds. These plants are being used as therapeutic purposes since the birth of mankind. The traditional healers normally utilize medicinal plants as crude drugs while scientists using the folk claim as guides to explore medicinal plants. Moringa oleifera is a famous edible plant having therapeutic and nutritive values. The present study was designed to cumulate the research data regarding to what extent, phytochemical, nutritional and glycemic control studies has been explored using its different extracts. The articles indicated that the powder, aqueous, methanol and ethanol extracts of Moringa oleifera(leaves, pods, seeds, stem and root bark) have significant therapeutic herbal potential to treat diabetes mellitus. Collectively, the mechanism behind is intestinal glucose inhibition, insulin release as well as decrease in insulin resistance probably regeneration of b-cells of pancreas, increase in glutathione and reduction in malondialdehyde. Conclusively, this article give descriptive information about antidiabetic effect, claimed marker compounds and proposed antihyperglycemic mechanism of a single plant. It can be suggested a potential herbal source to treat diabetes mellitus as being widely accepted by major population as nutrition and therapeutic agent.

关键词： Antihyperglycemic Aqueous Ethanol Moringa oleifera Antidiabetic

In vivo hypoglycemic investigation, antihyperglycemic and antihyperlipidemic potentials of Pereskia bleo Kunth. in normal and streptozotocin-induced diabetic rats

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Asian Pacific Journal of Tropical Biomedicine 2019年第2期9卷 73-79页

作者： Anis Najwa abdul Rani Roziahanim Mahmud Norliyana Amran Mohd zaini Asmawi Nornisah Mohamed Shanmugapriya Perumal School of Pharmaceutical Sciences Universiti Sains Malaysia

Objective: To elucidate the in vivo hypoglycemic capability, antihyperglycemic and antihyperlipidemic activities of Pereskia bleo(Kunth) leaves extracts and bioactive fraction. Methods: The various solvent extracts of Pereskia bleo were investigated for the hypoglycemic and antihyperglycemic activities using a relevant in vivo normal rat model and streptozotocininduced diabetic rat model with glibenclamide and metformin utilized as positive controls. The effects of the most potent extract and its bioactive fraction on the insulin level, lipid profile and body weight of the diabetic rats were also analyzed. Results: All the extracts showed no hypoglycemic effect while petroleum ether, chloroform and aqueous extracts demonstrated significant(P<0.05) reduction in blood sugar level in the intraperitoneal glucose tolerance test. Aqueous extract and aqueous fraction significantly(P<0.05) reduced the blood glucose level in streptozotocin-induced diabetic rats as early as day 6 compared to the diabetic control as well as significantly restored the serum insulin of diabetic rats. Moreover, the aqueous extract and aqueous fraction disclosed a significant(P<0.05) reduction in total cholesterol, triglycerides, and low-density lipoprotein levels. An elevation in high-density lipoprotein as well as improved body weight loss of the diabetic rats were also observed. Conclusions: In summary, Pereskia bleo appears effective in the management of diabetes and correlated impairments arising from high blood sugar level. Further studies will possibly bring about the discovery of effective and secure plant derived antidiabetic drugs.

关键词： Antihyperglycemic Antihyperlipidemic Pereskia bleo Aqueous fraction Hypoglycemic

Antidiabetic and antioxidant activities of Nypa fruticans Wurmb. vinegar sample from Malaysia

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Asian Pacific Journal of Tropical Medicine 2015年第8期8卷 589-597页

作者： Nor Adlin Yusoff Mun Fei Yam Hooi Kheng Beh Khairul Niza abdul Razak Tri Widyawati Roziahanim Mahmud Mariam Ahmad Mohd zaini Asmawi School of Pharmaceutical Sciences Universiti Sains Malaysia Integrative Medicine Cluster Advanced Medical and Dental InstituteUniversiti Sains Malaysia Pharmacology Department Medical FacultyUniversity of Sumatera Utara

Objective: To study the antidiabetic and antioxidant activities of nipa palm vinegar(NPV) used in traditional Malay medicine for treating diabetes. Methods: NPV was extracted using liquid-liquid extraction method and the obtained samples were subjected to antidiabetic studies using normal and streptozotocin-induced diabetic rat models whereas antidoxidant activities were investigated via in vitro antioxidant tests namely 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azinobis-3-ethylbenzothiozoline-6-sulfonic acid free radicals scavenging activities and the reducing power assay. Results: Single administration of NPV and its extracts were not effective in both normal and diabetic rats. In intraperitoneal glucose tolerance test, NPV and its aqueous extract showed significant blood glucose lowering effect. In the sub-acute study, compared with the diabetic control, aqueous extract of NPV showed the most notable blood glucose lowering effect(56.6%) and a significant improvement in serum insulin levels(79.8%, P<0.05). To assess NPV's antioxidant activity, three in vitro antioxidant tests were employed: 2,2-diphenyl-1-picryhydrazyl and 2,2'-azinobis-3-ethylbenzothiozoline-6-sulfonic acid free radical-scavenging assays, and the reducing power assay. Ethyl acetate extract had the greatest antioxidant potential and content of phenolic and flavonoid compounds. A linear positive correlation between the antioxidant parameters was observed. Chemical profiling analysis of aqueous extract of NPV revealed the presence of acetic acid(35.25%), the main active constituent which significantly contributed to the observed antidiabetic activity. Conclusions: Aqueous extract of NPV possesses antihyperglycaemic activities comparable to the metformin, while the ethyl acetate extract precipitated significant antioxidant effects attributable to its high phenolic content. These findings suggest that antioxidant compounds of NPV do not contribute much towards the overall observed antidiabetic effect.

关键词： Nypa fruticans Wurmb. Vinegar Antidiabetic Streptozotocin-induced diabetes Antioxidant Phenolics

Seroprevalence of dengue among healthy adults in a rural community in Southern Malaysia:a pilot study

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Infectious Diseases of Poverty 2018年第1期7卷 1-13页

作者： Amreeta Dhanoa Sharifah Syed Hassan Nowrozy Kamar Jahan Daniel D.Reidpath Quek Kia Fatt Mohtar Pungut Ahmad Cheong Yuet Meng Lau Wee Ming Anuar zaini Zain Maude Elvira Phipps Iekhsan Othman Aman Bin Rabu Rowther Sirajudeen Ahmad abdul Basitz Ahmad Fatan Faidzal Adlee Ghafar Hamdan Bin Ahmad Pascale Allotey Jeffrey Cheah School of Medicine and Health Sciences Monash University MalaysiaJalan Lagoon SelatanBandar Sunway47500 Petaling JayaMalaysia Segamat District Public Health Office Ministry of Health MalaysiaPeti Surat 102Jalan Gudang UbatKampung Gubah85000 SegamatJohor Darul TakzimMalaysia Infection and Immunity Cluster Tropical Medicine and Biology PlatformMonash University MalaysiaJalan Lagoon SelatanBandar Sunway47500 Petaling JayaMalaysia South East Asia Community Observatory(SEACO) 146 Jalan Sia Her YamSuite 601-606Wisma Centrepoint85000 SegamatJohor Darul TakzimMalaysia Hospital Segamat Ministry of Health MalaysiaKM 6Jalan Genuang85000 SegamatJohor Darul TakzimMalaysia Universiti Sains Malaysia 11800 GelugorPenangMalaysia.

Background:The frequency and magnitude of dengue epidemics continue to increase exponentially in Malaysia,with a shift in the age range predominance toward adults and an expansion to rural *** this,information pertaining to the extent of transmission of dengue virus(DENV)in the rural community is *** communitybased pilot study was conducted to establish DENV seroprevalence amongst healthy adults in a rural district in Southern Malaysia,and to identify influencing ***:In this study undertaken between April and May 2015,a total of 277 adult participants were recruited from households across three localities in the Sungai Segamat subdistrict in Segamat *** were tested for immunoglobulin G(IgG)(Panbio®Dengue Indirect IgG ELISA/high-titer capture)and immunoglobulin M(IgM)(Panbio®)*** plaque reduction neutralization test(PRNT)was conducted on random samples of IgGpositive sera for further *** history and a recall of previous history of dengue were collected through interviews,whereas sociodemographic information was obtained from an existing ***:The overall seroprevalence for DENV infection was 86.6%(240/277)(95%CI:83-91%).Serological evidence of recent infection(IgM/high-titer capture IgG)was noted in 11.2%(31/277)of participants,whereas there was evidence of past infection in 75.5%(209/277)of participants(indirect IgG minus recent infections).The PRNT assay showed that the detected antibodies were indeed specific to *** multivariate analysis showed that the older age group was significantly associated with past DENV *** increased with age;48.5%in the age group of45 years(P<0.001).No associations with occupation,study site,housing type,comorbidity,educational level,and marital status were observed,although the latter two were statistically significant in the univariate *** of the studied factors were significantl

关键词： Dengue Dengue virus Rural Community-based study Seroprevalence Subclinical infection Malaysia