检索结果-南通市图书馆

Frequency of Neurological Disorders and Related EEG Finding in a Tertiary Care Hospital of Karachi

Journal of Biosciences and Medicines 2019年第11期7卷 56-64页

作者： Danish Mohammad Syeda Saba Zaidi Bina Fawad Muhammad Fazal Hussain Qureshi zain jawed abubaker Muhammad Zubair Shaikh Muzna Shah Mahira Lakhani Sara Sadiq Ziauddin University Karachi Pakistan Department of Neurology Liaquat National Hospital Karachi Pakistan Department of Community Health Sciences Ziauddin University Karachi Pakistan Department of Physiology CMH Institute of Medical Sciences Bahawalpur Pakistan

Background: Electroencephalogram (EEG) is defined as a method of detecting brain waves signifying the electrical conductivity of the brain. Globally, EEG is used to further classify neuropsychiatric disorders. Objective: To evaluate the prevalence of abnormal EEGs and related neurological disorders and it’s correlation with age and gender. Methodology: A descriptive cross sectional study was conducted in Neurology department, Ziauddin hospital, Karachi, Pakistan from June 2018 to May 2019. A total of 440 individuals based on inclusion criteria were selected through Non-probability consecutive sampling. Informed consent was obtained from study participants. A self-designed structured questionnaire and EEG record were used for data collection. Data were entered and analyzed using SPSS v 20. Mean and standard deviation was calculated for numerical variable and frequency and percentages were calculated for categorical variable. Independent t-test and chi square was used to check association of abnormal EEG with age and gender. P value of ≤0.05 was considered statistically significant. Results: The mean age of study participants was 52.98 ± 22.68 years. There were 54.5% (n = 240) males. Approximately 45.2% (n = 199) participants had predisposing condition which can lead to abnormal EEG. EEG records of 39.8% (n = 175) of the patients was normal while 60.2% (n = 265) had abnormal records. Diffuse neuronal dysfunction consistent with encephalopathy was found in 45.2%. Mild neuronal dysfunction consistent with encephalopathy accounted for 33.5% of cases. Significant difference was found in Abnormal EEG among different age group (p = 0.01). Chi square shows an association between abnormal EEG and male gender (p = 0.025). Conclusion: EEG plays a vital role in the diagnosis of neuropsychiatric conditions in developing countries. EEGs can further help to determine the relationship of different neuropsychiatric conditions and can help in early diagnosis and better prognosis.

关键词： Neurological Disorders EEG Association

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fuzzy User Access Trust Model for Cloud Access Control

引用

Computer Systems Science & Engineering 2023年第1期44卷 113-128页

作者： Aakib jawed Khan Shabana Mehfuz Department of Electrical Engineering Jamia Millia IslamiaNew Delhi110025India

Cloud computing belongs to a set of policies,protocols,technologies through which one can access shared resources such as storage,applications,net-works,and services at relatively low *** the tremendous advantages of cloud computing,one big threat which must be taken care of is data security in the *** are a dozen of threats that we are being exposed to while avail-ing cloud *** identity and access management,insecure inter-faces and Applications interfaces(APIs),hijacking,advanced persistent threats,data threats,and many more are certain security issues with the cloud *** and service providers face a huge challenge to ensure the security and integ-rity of both network and *** overcome these challenges access control mechanisms are *** access control mechanisms fail to monitor the user operations on the cloud platform and are prone to attacks like IP spoofing and other attacks that impact the integrity of the *** ensuring data integrity on cloud platforms,access control mechanisms should go beyond authentication,identification,and ***,in this work,a trust-based access control mechanism is proposed that analyzes the data of the user behavior,network beha-vior,demand behavior,and security behavior for computing trust value before granting user *** method that computes thefinal trust value makes use of the fuzzy logic *** trust value-based policies are defined for the access control mechanism and based on the trust value outcome the access control is granted or denied.

关键词： Cloud architecture fuzzy logic trust-based access mechanism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

GDF15 promotes prostate cancer bone metastasis and colonization through osteoblastic CCL2 and RANKL activation

引用

Bone Research 2022年第1期10卷 150-164页

作者： jawed Akhtar Siddiqui Parthasarathy Seshacharyulu Sakthivel Muniyan Ramesh Pothuraju Parvez Khan Raghupathy Vengoji Sanjib Chaudhary Shailendra Kumar Maurya Subodh Mukund Lele Maneesh Jain Kaustubh Datta Mohd Wasim Nasser Surinder Kumar Batra Department of Biochemistry and Molecular Biology University of Nebraska Medical CenterOmahaNEUSA Department of Pathology and Microbiology University of Nebraska Medical CenterOmahaNEUSA Fred&Pamela Buffett Cancer Center University of Nebraska Medical CenterOmahaNE 68198-5870USA Eppley Institute for Research in Cancer and Allied Diseases University of Nebraska Medical CenterOmahaNEUSA

Bone metastases occur in patients with advanced-stage prostate cancer(PCa). The cell-cell interaction between PCa and the bone microenvironment forms a vicious cycle that modulates the bone microenvironment, increases bone deformities, and drives tumor growth in the bone. However, the molecular mechanisms of PCa-mediated modulation of the bone microenvironment are complex and remain poorly defined. Here, we evaluated growth differentiation factor-15(GDF15) function using in vivo preclinical PCa-bone metastasis mouse models and an in vitro bone cell coculture system. Our results suggest that PCa-secreted GDF15 promotes bone metastases and induces bone microarchitectural alterations in a preclinical xenograft model. Mechanistic studies revealed that GDF15 increases osteoblast function and facilitates the growth of PCa in bone by activating osteoclastogenesis through osteoblastic production of CCL2 and RANKL and recruitment of osteomacs. Altogether, our findings demonstrate the critical role of GDF15 in the modulation of the bone microenvironment and subsequent development of PCa bone metastasis.

关键词： GDF15 metastasis RANKL

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Novel virulence factor dupA of Helicobacter pylori as an important risk determinant for disease manifestation:An overview

引用

World Journal of Gastroenterology 2020年第32期26卷 4739-4752页

作者： jawed Alam Avijit Sarkar Bipul Chandra Karmakar Mou Ganguly Sangita Paul Asish K Mukhopadhyay Division of Infectious Diseases Institute of Life ScienceBhubaneswar 751023India Division of Bacteriology ICMR-National Institute of Cholera and Enteric DiseasesKolkata 700010India

Helicobacter pylori(***)is a microaerophilic,Gram-negative,human gastric pathogen found usually in the mucous lining of *** infects more than 50%of the world’s population and leads to gastroduodenal *** outcome of disease depends on mainly three factors:Host genetics,environment and bacterial *** these,bacterial virulence factors such as cagA,vacA are well known for their role in disease ***,based on the global epidemiological results,none of the bacterial virulence(gene)factors was found to be associated with particular diseases like duodenal ulcer(DU)in all ***,substantial importance has been provided for research in strain-specific genes outside the cag pathogenicity island,especially genes located within the plasticity *** found within the plasticity regions was first demonstrated in 2005 and was proposed for duodenal ulcer development and reduced risk of gastric cancer in certain geographical *** to the discrepancies in report from different parts of the world in DU development related to *** virulence factor,dupA became an interesting area of research in elucidating the role of this gene in the disease *** this review,we shed light on the detailed information available on the polymorphisms in dupA and their clinical *** have critically appraised several pertinent studies on dupA and discussed their merits and *** review also highlights dupA gene as an important biomarker for DU in certain populations.

关键词： Helicobacter pylori Plasticity region Duodenal ulcer Gastric cancer dupA gene

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of thrombectomy on oedema progression and clinical outcome in patients with a poor collateral profile

引用

Stroke & Vascular Neurology 2021年第2期6卷 222-229页

作者： Gabriel Broocks Andre Kemmling Tobias Faizy Rosalie McDonough Noel Van Horn Matthias Bechstein Lukas Meyer Gerhard Schon jawed Nawabi Jens Fiehler Helge Kniep Uta Hanning Department of Diagnostic and Interventional Neuroradiology University Medical Center Hamburg-EppendorfHamburgGermany Institute of Neuroradiology University Hospital of LuebeckLuebeckGermany Neuroradiology WestpfalzklinikumKaiserslauternGermany Department of Diagnostic and Interventional Neuroradiology Stanford UniversityStanfordCaliforniaUSA Department of Medical Biometry and Epidemiology University Medical Center Hamburg EppendorfHamburgGermany Department of Radiology CharitéUniversitätsmedizin BerlinBerlinGermany

Background and purpose The impact of the cerebral collateral circulation on lesion progression and clinical outcome in ischaemic stroke is well ***,collateral status modifies the effect of endovascular treatment and was therefore used to select patients for therapy in prior *** purpose of this study was to quantify the effect of vessel recanalisation on lesion pathophysiology and clinical outcome in patients with a poor collateral *** and methods 129 patients who had an ischaemic stroke with large vessel occlusion in the anterior circulation and a collateral score(CS)of 0-2 were *** profile was defined using an established 5-point scoring system in CT *** progression was determined using quantitative lesion water uptake measurements on admission and follow-up CT(FCT),and clinical outcome was assessed using modified Rankin Scale(mRS)scores after 90 *** Oedema formation in FCT was significantly lower in patients with vessel recanalisation compared with patients with persistent vessel occlusion(mean 19.5%,95%CI:17%to 22%vs mean 27%,95%CI:25%to 29%;p<0.0001).In a multivariable linear regression analysis,vessel recanalisation was significantly associated with oedema formation in FCT(ß=−7.31,SD=0.015,p<0.0001),adjusted for CS,age and Alberta Stroke Program Early CT Score(ASPECTS).Functional outcome was significantly better in patients following successful recanalisation(mRS at day 90:4.5,IQR:2-6 vs 5,IQR:5-6,p<0.001).Conclusion Although poor collaterals are known to be associated with poor outcome,endovascular recanalisation was still associated with significant oedema reduction and comparably better outcome in this patient *** with poor collaterals should not generally be excluded from thrombectomy.

关键词： collateral patients edema

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research on Investment Decision Method for Transportation System Based on PPP Model

Research on Investment Decision Method for Transportation Sy...

引用

作者： jawed Kootwal 东南大学

学位级别：硕士

在阿富汗,传统采购方法已不能及时完成项目并导致了一些关于项目成本、质量以及可持续性方面的担忧。因此,公共私营合作制(PPP)已被当做一种可选且重要的工具,用于吸引项目社会投资和相应的政府资金。本研究在分析交通PPP关键问题以及... 详细信息

在阿富汗,传统采购方法已不能及时完成项目并导致了一些关于项目成本、质量以及可持续性方面的担忧。因此,公共私营合作制(PPP)已被当做一种可选且重要的工具,用于吸引项目社会投资和相应的政府资金。本研究在分析交通PPP关键问题以及阿富汗道路交通现状的基础上,提出了一个基于PPP的道路投资决策模型并进行了应用分析。本文指出了PPP在阿富汗高速建设中起到的重要作用,即PPP能实现阿富汗高速的盈利性以及可持续性。本文以阿富汗最长的高速(Kabul-Herat)为例,进一步对PPP在阿富汗道路工程中的可行性进行评价。关于调研-改造-操作-转移(SROT)这个新模型的应用情况,本文对中国沈大高速运营情况进行分析并对其PPP经验进行借鉴。具体的,本文针对沈大高速以及Kabul-Herat高速的可行性、投标过程、建造过程、运营过程、转移过程以及风险分配和管理等展开了研究。尽管新老沈大高速项目已经成功完结,但项目实施过程中仍存在一些问题。例如新老高速承建商的自动选择、建造成本超支、项目筹资带来的政府公债、过路费用征收金额以及征收次数增多给民众带来的负荷加重、新技术带来的总成本增加等问题。另外,本文还提出了一些未来研究方向,例如深入分析流量和收益(T&R)以及PPP道路项目对阿富汗经济增长的影响。

关键词：公共私营合作制投资交通阿富汗

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Mineragraphic Study of Manganese Ore Deposits of Kandri, Mansar, Beldongri and Satak Mines, Nagpur District (Maharashtra) Central India

引用

International Journal of Geosciences 2014年第7期5卷 710-727页

作者： Talat jawed F. N. Siddiquie Department of Geology Aligarh Muslim University Aligarh India

In Nagpur, M.P.-Maharashtra Manganese Belt is exposed which is part of Sausar Belt. In Nagpur, four manganese mines viz Mansar, Kandri, Beldongri and Satak are selected for the ore microscopic study. These mining areas are situated in that part of Central India which are highly deformed and metamorphosed and are characterised by high grade amphibolite facies to low grade greenschist facies. The Precambrian manganese ore deposits of Nagpur are formed by the metasediments of Sausar belt which is rich in manganese sediments. The manganese ores of the study area are co-folded with distinct rock types i.e. “gondites” and predominantly composed of a mixture of braunite, bixbyite, hausmannite, hollandite, jacobsite, vredenburgite, pyrolusite, cryptomelane and psilomelane. The dominant rocks are tirodi migmatitic gneiss, argillaceous and calcareous rock types. This paper discusses the mineralogy of the manganese ores of Kandri, Mansar, Satak and Beldongri. After the careful assessment of mineralogy, texture and paragenesis of the manganese ore of the study area, it has been concluded that the manganese ores of the study area are formed by the multiple processes i.e. metamorphism and supergene enrichment. These supergene enrichments are evidence of colloidal influx. Occurrence of free braunite, free hausmannite and free jacobsite indicates the high grade metamorphism. Pyrolusite, rhodonite, and psilomelane-cryptomelane are formed by supergene enrichment. The presence of lamellar twinning in braunite indicates about shear pressure. In this area the different manganese mineral assemblages and their textures suggest about the occurrence of different metamorphic activity and depositional environment. The texture and paragenesis of manganese ore of the study area are discussed here.

关键词： Sausar Belt Precambrian Metasediments Manganese Mineralization Central India

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Temporal change assessment of agricultural land by Satellite Remote Sensing (SRS) technique

引用

Natural Science 2013年第6期5卷 689-694页

作者： Gohar Ali Mahar Razzaq Ahmed Mohammad jawed Iqbal Ain Zubaida Unit for Rehabilitation and Groundwater Research King Abdulaziz University Jeddah KSA Department of Geography Federal Urdu University of Art Sciences and Technology Karachi Pakistan

Agriculture is the vital economic activity of rural society in nearly all of Pakistan. The Winder-Sonmiani area located at the Makran coast near the city of Hub in Pakistan is economically very promising. Cropping, horticulture, fruit farming and animal husbandry are the common land use activities in the area while fishing along the coast is an important economic activity. Owing to the use of the Satellite Remote Sensing technique (SRST), the triangular basin shape structure of the Winder area has been found to be spatially very promising for agricultural activities. Positive change in the use of agriculture land was detected from the Satellite images of different periods. Use of modern technology and incentives provided by the government have advanced improvement in agriculture.

关键词： Agriculture Spatiotemporal Satellite Remote Sensing (SRS) GIS Landsat

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of Seasonal Low on Sea Level Rise

引用

International Journal of Geosciences 2019年第1期10卷 29-38页

作者： Mirza Jawwad Baig M. jawed Iqbal Saba Naz Institute of Space & Planetary Astrophysics (ISPA) University of Karachi Karachi Pakistan Department of Mathematics University of Karachi Karachi Pakistan

Every region around the globe has its unique climatic conditions which are set based on different orographic constant and atmospheric dynamic features. These features posses’ variability on different time scales. Determining the local sea level change based on terrestrial non-tidal, short-term variability is complicated. Some internal mechanisms of ocean are also taking place along with the external physical ones. We show that variability at Sindh-Baluchistan coastal belt can be greatly explained via dimensional indices of the position and intensity of the atmospheric center of action (COAs). This technique has already proved its usefulness at number of location especially in Northern Atlantic. It takes into account the changes in the atmospheric pressure which is exerted on the sea surface influencing the variability in sea level on seasonal scale and on inter-annual basis. As warming causes thermal expansion of water it also causes changes in atmospheric circulation. Both of these processes affect the sea level variability on their respective time scales. Atmospheric being the quicker one of the two to pass on the effect is also more influential to explain the variability in local sea level. In this attempt the COA approach is used to assess the impact of low pressure on local sea levels.

关键词： Sea Level South Asia Low pressure Indian Ocean

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Analysis of Robust Performance of Active Suspension Control of Vehicle with Parametric uncertainty

Analysis of Robust Performance of Active Suspension Control ...

引用

第二十三届中国控制会议

作者： jawed Akhtar Dr.Vali Uddin Pakistan Iqra University KarachiPakistan

＜正＞ This paper deals with the analysis an active suspension system control using LMI approach. First an issue of modeling a real physical system is discussed. We model the parameter uncertainty by the polyhedral system, in which the real system is assumed to reside. Second, based on the set of plant models, we setup robust performance control objectives by choosing weighting functions on inputs and outputs. Third, we make use of the LMI approach for the state feedback controller design which meets multiple objectives of stability and robustness. In his paper we maintained robust stability by checking stability at the edges of the polyhedral with the help of quadratic stability criterion and made LMI formulation for H2and H∞for different specifications of active suspension system with parametric uncertainty. We have investigated the system at different indexes of performances and robustness, have shown the trade-off ion H2 performance as we increase robustness including parametric uncertainties, finally we have made static state feedback gain at different robustness indexes.

关键词： Robust Controller analysis parameter uncertainty LMI Active suspension system.

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：