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Barbi.urate Coma: Rebound and Refractory Hyperkalemi.

Case Reports i. Cli.i.al Medi.i.e 2014年第5期3卷 304-308页

作者： Bonni. C. Greenwood Chri.topher D. Adams zain i. khalpey Peter C. Hou Department of Emergency Medi.i.e Brigham and Women’s Hospital Boston USA Department of Pharmacy Brigham and Women’s Hospital Boston USA Department of Surgery University of Arizona Tucson USA

Purpose: To descri.e a traumati. brai. i.jury pati.nt who experi.nced profound dyskalemi. upon the i.i.i.ti.n and cessati.n of a pentobarbi.al i.fusi.n and propose management opti.ns for future pati.nts recei.i.g thi. i.terventi.n. Methods: Case report. Results: Case report. Conclusi.ns: Dyskalemi. has become an anti.i.ated si.e effect of hi.h dose barbi.urate i.fusi.ns i. the setti.g of elevated i.tracrani.l pressure. Hypokalemi. duri.g the admi.i.trati.n of a barbi.urate i.fusi.n has been i.enti.i.d wi.hi. thi. pati.nt populati.n and was an expected adverse event duri.g thi. i.terventi.n. However, i. thi. case we observed a si.ni.i.ant and compli.ated refractory hyperkalemi. upon cessati.n of the barbi.urate i.fusi.n whi.h requi.ed aggressi.e management. An objecti.e causali.y assessment suggests that thi. adverse event was possi.ly related to pentobarbi.al. What thi. case documents that other cases have not i. that upon re-i.troducti.n of the pentobarbi.al i.fusi.n, serum potassi.m levels di. not normali.e. Thi. questi.ns whether severe rebound hyperkalemi. i. a pharmacodynami. or i.fusi.n-related reacti.n. More data i. needed to i.enti.y the mechani.m of thi. adverse event and recommend an appropri.te treatment approach.

关键词： Barbi.urate Rebound Refractory Hyperkalemi.

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Human Amni.ti. Membrane Promotes Anti.i.robi.l Mi.roenvi.onment i. a Devi.e-Related i.fecti.n

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Journal of Bi.medi.al Sci.nce and Engi.eeri.g 2016年第2期9卷 122-126页

作者： Ali.e S. Ferng Katheri.e M. Marsh Ti. R. Pi.i.i.n Alana Connell Courtney Hemphi.l Samata Pai.y Ray Runyan John Konhi.as zain khalpey Department of Surgery Division of Cardiothoracic Surgery University of Arizona Tucson AZ USA College of Medi.i.e-Tucson University of Arizona Tucson AZ USA Department of Physi.logi.al Sci.nces University of Arizona Tucson AZ USA Department of Bi.medi.al Engi.eeri.g University of Arizona Tucson AZ USA Banner-Uni.ersi.y Medi.al Center Tucson AZ USA Amni. Technology LLC Phoenix AZ USA Department of Cellular and Molecular Medi.i.e University of Arizona Tucson AZ USA Department of Anesthesi. University of Arizona Tucson AZ USA Department of Medi.al i.agi.g University of Arizona Tucson AZ USA

Hospi.al i.qui.ed post-operati.e i.fecti.ns are a leadi.g cause of morbi.i.y and mortali.y i. pati.nts recei.i.g left ventri.ular assi.t devi.es. We present the case of a pati.nt who acqui.ed Candi.a albi.ans and Staphylococci.i.fecti.ns followi.g left ventri.ular assi.t devi.e i.plantati.n. Use of standard anti.i.ti.s caused the i.fecti.n to worsen, thus an amni.ti. membrane patch was used as a last-resort treatment. Wi.hi. 6 weeks of the amni.ti. membrane patch treatment, the i.fecti.n resolved, the wound appeared excepti.nally clean upon i.specti.n, and granulati.n ti.sue was present. After the i.fecti.n resolved, a successful lati.si.usdorsi.ti.sue flap procedure was completed and the pati.nt made a full recovery.

关键词： Anti.i.robi.l Amni.ti. Membrane Ventri.ular Assi.t Devi.e

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