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TURBULENT MIXING AND EVOLUTION IN A STABLY STRATIFIED FLOW WITH A TEMPERATURE STEP

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Journal of Hydrodynamics 2009年第1期21卷 84-92页

作者： qiu Xiang ZHANG Dao-xiang LU Zhi-ming LIU Yu-lu Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China Department of Mathematics Shanghai University Shanghai 200444 China

Large-Eddy Simulation （LES） is applied to examine the turbulent mixing and evolution in a stably stratified flow with a thermally sharp interface. Turbulent velocity intensities and turbulent kinetic energy are analyzed by considering the mean shear and stratification effects. The evolution of turbulent mixing layer and turbulent structures are mainly investigated. The results show that the streamwise intensities are much larger than the vertical intensities, and vertical fluctuations decay more rapidly at the presence of stratification. The qualitatively computational results suggest that the mixing layer, defined by the mean temperature, inclines to the side with small inlet velocity. The evolution of the half-width of the mixing layer shows two different slopes. The turbulent structure with high vorticity is restricted in the mixing layer especially in strong stratified cases.

关键词： stratified turbulence turbulent mixing turbulent structure Large-Eddy Simulation (LES)

学习贯彻党的十六届六中全会精神,努力构建和谐校园

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贵阳学院学报（社会科学版） 2007年第1期2卷 1-8页

作者：蒙秋明贵阳学院贵州贵阳550005

古往今来,和谐社会都是人们向往和追求的理想社会。只有在马克思主义的科学指导下,和谐社会才有可能实现。十六届六中全会通过的《中共中央关于构建社会主义和谐社会若干重大问题的决定》中关于社会和谐是中国特色社会主义的本质属性的... 详细信息

古往今来,和谐社会都是人们向往和追求的理想社会。只有在马克思主义的科学指导下,和谐社会才有可能实现。十六届六中全会通过的《中共中央关于构建社会主义和谐社会若干重大问题的决定》中关于社会和谐是中国特色社会主义的本质属性的论断,是中国共产党半个多世纪艰辛探索、不懈奋斗的实践和认识成果,是我们构建和谐校园的指南。

关键词：和谐社会根本属性和谐校园

Physiognomy： Personality Traits Prediction by Learning

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International Journal of Automation and computing 2017年第4期14卷 386-395页

作者： Ting Zhang Ri-Zhen Qin qiu-Lei Dong Wei Gao Hua-Rong Xu Zhan-Yi Hu National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences Beijing 100190 China Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences Beijing 100190 Chins University of Chinese Academy of Sciences Beijing 100049 China Department of Computer Science &: Technology Xiamen Institute of Technology Xiamen 361024 China

Evaluating individuals＇ personality traits and intelligence from their faces plays a crucial role in interpersonal relationship and important social events such as elections and court sentences. To assess the possible correlations between personality traits （also measured intelligence） and face images, we first construct a dataset consisting of face photographs, personality measurements, and intelligence measurements. Then, we build an end-to-end convolutional neural network for prediction of personality traits and intelligence to investigate whether self-reported personality traits and intelligence can be predicted reliably from a face image. To our knowledge, it is the first work where deep learning is applied to this problem. Experimental results show the following three points： 1）＂Rule-consciousness＂ and ＂Tension＂ can be reliably predicted from face images. 2） It is difficult, if not impossible, to predict intelligence from face images, a finding in accord with previous studies. 3） Convolutional neural network （CNN） features outperform traditional handcrafted features in predicting traits.

关键词： Personality traits physiognomy face image deep learning convolutional neural network (CNN).

Flavonoid-Rich Extract of Oldenlandia diffusa(Willd.)*** Gastric Cancer by Activation of Caspase-Dependent Mitochondrial Apoptosis

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Chinese Journal of Integrative Medicine 2023年第3期29卷 213-223页

作者： LING Jia-yin WANG qiu-lan LIANG Hao-nan LIU Qing-bo YIN Dong-hong LIN Li First School of Clinical Medicine Gansu University of Chinese MedicineLanzhou(730000)China Gansu Provincial Hospital Lanzhou(730000)China College of Pharmacy Gansu University of Chinese MedicineLanzhou(730000)China Institute of Chinese(Tibetan)Medicine Resources Gansu University of Chinese MedicineLanzhou(730000)China

Objective:To evaluate the apoptosis and cycle arrest effects of Oldenlandia diffusa flavonoids on human gastric cancer cells,determine the action mechanisms in association with the mitochondrial dependent signal transduction pathway that controls production of reactive oxygen species(ROS),and evaluate the pharmacodynamics of a mouse xenotransplantation model to provide a reference for the use of flavonoids in prevention and treatment of gastric ***:Flavonoids were extracted by an enzymatic-ultrasonic assisted method and purified with D-101 *** components were characterized by high-performance liquid *** lines MKN-45,AGS,and GES-1 were treated with different concentrations of flavonoids(64,96,128,and 160μg/mL).The effect of flavonoids on cell viability was evaluated by MTT method,and cell nuclear morphology was observed by Hoechst *** apoptosis rate and cell cycle phases were measured by flow cytometry,the production of ROS was detected by laser confocal microscope,the mitochondrial membrane potential(MMP)were observed by fluorescence microscope,and the expression of apoptotic proteins related to activation of mitochondrial pathway were measured by ***-45cells were transplanted into BALB/c nude mice to establish a xenograft tumor *** and eosin staining was used to reveal the subcutaneous tumor *** tumor volume and tumor weight were measured,the expression levels of proliferation markers proliferating cell nuclear antigen(PCNA)and Ki-67were detected by immunohistochemistry,and the expression levels of CA72-4 were measured by enzyme linked immunosorbent ***:Oldenlandia diffusa flavonoids inhibited proliferation of MKN-45 and AGS human gastric cancer cells,arrested the cell cycle in G1/S phase,induced accumulation of ROS in the process of apoptosis,and altered *** addition,flavonoids increased Apaf-1,Cleaved-Caspase-3,and Bax,and decreased Cyclin A,Cdk2,Bcl-2,Pro-Caspase-9,a

关键词： Chinese medicine Oldenlandia diffusa flavonoids gastric cancer apoptosis mitochondria

Atmospheric gaseous elemental mercury in the Arctic:role of long-range transport and sea ice

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Advances in Polar Science 2024年第4期35卷 449-458页

作者： qiu Yue YUE Fange JIANG Bei XIE Zhouqing Institute of Polar Environment&Anhui Key Laboratory of Polar Environment and Global Change Department of Environmental Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China Suzhou Institute for Advanced Study University of Science and Technology of ChinaSuzhou 215123China

The potential sources of atmospheric mercury in the Arctic are still not well ***,we analyzed the round-year observations of atmospheric gaseous elemental mercury(GEM)concentrations in 2010 at two sites in the Arctic:Zeppelin Observatory(78.90°N,11.88°E)and Alert Observatory(82.47°N,62.50°W).The results showed clearly different characteristics at these two *** the winter of 2010,the long-range transport of anthropogenic emissions was the dominant factor for elevated GEM at Zeppelin Observatory while which had little contribution to GEM at Alert *** change in GEM at Zeppelin Observatory during January,February and October was dominated by long-range transported anthropogenic *** emission inventory combined with backward trajectoryanalysis suggested that the main sources were unintentional industrial sources,stationary combustion sources,and intentional use and product waste-associated sectors,which contributed 49%,33%,and 18%,*** source contribution function analysis was then conducted and found that Europe was the important source *** the summer of 2010,sea ice concentration was an important factor affecting GEM at Alert Observatory while which had little effect on GEM at Zeppelin *** results further indicated the role of anthropogenic sources and climate warming on the spatial variation in GEM over the Arctic.

关键词： mercury anthropogenic emissions sea ice Arctic

An InP-Based Dual-Depletion-Region Electroabsorption Modulator with Low Capacitance and Predicted High Bandwidth

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Chinese Physics Letters 2011年第11期28卷 124-127页

作者： SHAO Yong-Bo ZHAO Ling-Juan YU Hong-Yan qiu Ji-Fang qiu Ying-Ping PAN Jiao-Qing WANG Bao-Jun ZHU Hong-Liang WANG Wei Key Laboratory of Semiconductor Materials Science Institute of SemiconductorsChinese Academy of SciencesP.O.Box 912Beijing 100083 School of Space Science and Physics Shandong University at WeihaiWeihai 264209

A novel dual-depletion-region electroabsorption modulator(DDR-EAM)based on InP at 1550nm is *** measured capacitance and extinction ratio of the DDR-EAM reveal that the dual depletion region structure can reduce the device capacitance significantly without any degradation of extinction ***,the bandwidth of the DDR-EAM predicted by using an equivalent circuit model is larger than twice the bandwidth of the conventional lumped-electrode EAM(L-EAM).

关键词： modulator extinction capacitance

Enhanced uptake and anti-maturation effect of celastrol-loaded mannosylated liposomes on dendritic cells for psoriasis treatment

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Acta Pharmaceutica Sinica B 2022年第1期12卷 339-352页

作者： Long Xi Zibei Lin Fen qiu Shaokui Chen Ping Li Xin Chen Zhenping Wang Ying Zheng State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao 999078China Beijing Hospital of Traditional Chinese Medicine Affiliated with Capital Medical UniversityBeijing 100050China Department of Dermatology School of MedicineUniversity of CaliforniaSan DiegoCA 92093USA

Psoriasis is an autoimmune skin disease in which dendritic cells(DCs) trigger the progression of psoriasis by complex interactions with keratinocytes and other immune cells. In the present study,we aimed to load celastrol, an anti-inflammatory ingredient isolated from Chinese herbs, on mannosylated liposomes to enhance DC uptake as well as to induce DC tolerance in an imiquimod-induced psoriasis-like mouse model. Mannose was grafted onto liposomes to target mannose receptors on DCs. The results demonstrated that compared with unmodified liposomes, DCs preferred to take up more fluorescence-labeled mannosylated liposomes. After loading celastrol into mannose-modified liposomes,they effectively inhibited the expression of maturation markers, including CD80, CD86 and MHC-II, on DCs both in vitro and in vivo. Additionally, after intradermal injection with a microneedle, celastrolloaded mannose-modified liposomes(CEL-MAN-LPs) achieved a superior therapeutic effect compared with free drug and celastrol-loaded unmodified liposomes in the psoriasis mouse model in terms of the psoriasis area and severity index, histology evaluation, spleen weight, and expression of inflammatory cytokines. In conclusion, our results clearly revealed that CEL-MAN-LPs was an effective formulation for psoriasis treatment and suggested that this treatment has the potential to be applied to other inflammatory diseases triggered by activated DCs.

关键词： Psoriasis Celastrol Mannose Liposome Anti-maturation Dendritic cells Microneedle Inflammation

Constitutive behavior and processing maps of low-expansion GH909 superalloy

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International Journal of Minerals,Metallurgy and Materials 2017年第4期24卷 432-443页

作者： Zhi-hao Yao Shao-cong Wu Jian-xin Dong qiu-ying Yu Mai-cang Zhang Guang-wei Han School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China The Fu Foundation School of Engineering and Applied Science Columbia University New York 10027 USA Beijing Institute of Aeronautical Materials Beijing 100095 China Department of High Temperature Materials Research Central Iron and Steel Research Institute Beijing 100081 China

The hot deformation behavior of GH909 superalloy was studied systematically using isothermal hot compression tests in a temperature range of 960 to 1040°C and at strain rates from 0.02 to 10 s−1with a height reduction as large as 70%. The relations considering flow stress, temperature, and strain rate were evaluated via power-law, hyperbolic sine, and exponential constitutive equations under different strain conditions. An exponential equation was found to be the most appropriate for process modeling. The processing maps for the superalloy were constructed for strains of 0.2, 0.4, 0.6, and 0.8 on the basis of the dynamic material model, and a total processing map that includes all the investigated strains was proposed. Metallurgical instabilities in the instability domain mainly located at higher strain rates manifested as adiabatic shear bands and cracking. The stability domain occurred at 960–1040°C and at strain rates less than 0.2 s−1; these conditions are recommended for optimum hot working of GH909 superalloy. © 2017, University of Science and Technology Beijing and Springer-Verlag Berlin Heidelberg.

关键词： Compression testing Constitutive equations Deformation Hot working Microstructural evolution Shear bands Strain Superalloys

氟烷基化和氟烷氧基化的研究 13. 2-卤四氟乙基物种的β-断裂

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化学学报 1987年第4期45卷 354-358页

作者：陈庆云裘再明中国科学院上海有机化学研究所中国科学院上海有机化学研究所上海

用典型自由基引发(hv,Cu,S2O42-,ABN,DBP等),可以使2-卤四氟碘乙烷（1）（XCF2CF2I,X=Cl,I）产生四氟乙烯。从而证实了2-卤四氟乙基自由基在温和实验条件下能够发生β-断裂。1与亲核试剂（如PPh3,F-,Cl-,Br-,CH3O-,PhS-等）作用结果,同... 详细信息

用典型自由基引发(hv,Cu,S2O42-,ABN,DBP等),可以使2-卤四氟碘乙烷（1）（XCF2CF2I,X=Cl,I）产生四氟乙烯。从而证实了2-卤四氟乙基自由基在温和实验条件下能够发生β-断裂。1与亲核试剂（如PPh3,F-,Cl-,Br-,CH3O-,PhS-等）作用结果,同样能得到四氟乙烯。这是符合离子型亲卤反应机理的。由此可见,1具有参与自由基机理和亲卤机理反应的双重性质。

关键词：四氟自由基游离基全氟代烃四氟乙烯乙基碘碘乙烷链烷基乙基