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Plant extract-loaded bacterial cellulose composite membrane for potential biomedical applications

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Journal of Bioresources and Bioproducts 2021年第1期6卷 26-32页

作者： Atiya Fatima Sumayia Yasir MohdShariq Khan Sehrish Manan Muhammad Wajid ullah Mazhar ul-islam Department of Chemical Engineering College of EngineeringDhofar UniversitySalalahSultanate of Oman Department of Biomedical Engineering Huazhong University of Science and TechnologyWuhan 430074China

Bacterial cellulose(BC)has been extensively explored as biomaterial for various biomedical applications owing to its non-toxic nature and unique structural morphology and impressive physicochemical and mechanical ***,its high production cost and lack of antimicrobial activity have restricted its large-scale production and therapeutic ***,the current study is aimed to devise a strategy for low-cost BC production and develop its composite with bioactive materials to bless it with antimicrobial ***,5 mm thick reticulated fibrous and highly porous BC was produced by utilizing the wasted rotten tomatoes as the production *** produced bacterial cellulose waste(BCW)(i.e.,produced from wastes)was ex-situ modified with bioactive plant extract(PE)obtained from Euclea schimperi,and the bactericidal activity of the developed BCW/PE was evaluated against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli through disc diffusion and colony forming unit(CFU)count *** BCW/PE composite showed high bactericidal activities against *** and produced clear inhibition zone whereas negligible activity was observed against ***,indicating its bactericidal activity mainly against the Gram-positive ***,this study illustrates that there is a huge potential for developing valuable biomaterials from food wastes and utilizing their liquid holding capabilities for value-added applications in medical and pharmaceutical fields.

关键词： Bacterial cellulose Food waste Plant extract Bactericidal activity Biomedical application

Long-term outcomes of titanium-nitride-oxide coated stents and drug-eluting stents in acute coronary syndrome:A systematic review and meta-analysis

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World Journal of Cardiology 2024年第5期16卷 293-305页

作者： Muhammad Ahmed Ali Fahim Afia Salman Hira Anas Khan Syed Muhammad Hasan Muskan FatimaBhojani Sarah Aslam Amna Zia ul Haq Vishal Reddy Bejugam Beena Muntaha Nasir Wajiha Gul Abdul Moeed Abdelrahman S Abdalla Muhammad Majid Muhammad Sohaib Asghar Md Al Hasibuzzaman Department of Internal Medicine Dow University of Health SciencesKarachi 74200Pakistan Department of Internal Medicine North Central Bronx HospitalBronxNY 10467United States Department of Urology Center for Academic MedicineStanford University School of MedicinePalo AltoCA 33872United States Department of Cardiovascular Imaging Cleveland ClinicClevelandOH 44195United States Division of Nephrology and Hypertension Mayo Clinic RochesterRochesterMN 55905United States Institute of Nutrition and Food Science University of DhakaDhaka 1000Bangladesh

BACKGROUND In severe cases of coronary artery disease,percutaneous coronary intervention provide promising *** stent used could be a drug-eluting stent(DES)or a titanium-nitride-oxide coated stent(TiNOS).AIM To compare the 5-year effectiveness and safety of the two stent *** The following systematic review and meta-analysis was conducted in accordance with the preferred reporting items for systematic reviews and meta-analysis guidelines,and PubMed/MEDLINE,Scopus,and Cochrane Central were searched from inception till August *** outcomes were major adverse cardiac events(MACE),cardiac death,myocardial infarction(MI),cardiac death or MI,and ischemia-driven total lesion revascularization(ID-TLR).RESulTS Four randomized controlled trials(RCT),which analyzed a sum total of 3045 patients with acute coronary syndrome(ACS)after a median follow-up time of 5 years were *** statistically insignificant,an increase in the ID-TLR was observed in patients receiving TiNOSs vs *** addition,MI,cardiac death and MI,and definite stent thrombosis(DST)were significantly decreased in the TiNOS *** analysis revealed no significant results with meta-regression presenting non-ST elevated MI(NSTEMI)as a statistically significant covariate in the outcome of *** TiNOS was found to be superior to DES in terms of MI,cardiac death or MI,and DST outcomes,however,the effect of the two stent types on ID-TLR and MACE was not significant.A greater number of studies are required to establish an accurate comparison of patient outcomes in TiNOS and DES.

关键词： Stents Drug-eluting Major adverse cardiac events All-cause death Meta-analysis

Buoyancy Effects in the Peristaltic Flow of a Prandtl-Eyring Nanofluid with Slip Boundaries

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Fluid Dynamics & Materials Processing 2023年第6期19卷 1507-1519页

作者： Hina zahir Department of Mathematics Shaheed Benazir Bhutto Women UniversityPeshawar25000Pakistan

The interaction of nanoparticles with a peristaltic flow is analyzed considering a Prandtl-Eyring fluid under various conditions,such as the presence of a heat source/sink and slip effects in channels with a *** problem has extensive background links with various fields in medical science such as chemotherapy and more in general nanotechnology.A similarity transformation is used to turn the original balance equations into a set of ordinary differential equations,which are then integrated *** investigation reveals that nanofluids have valuable thermal capabilitises.

关键词： Curved channel Prandtl-Eyring nanofluid slip conditions flexible walls heat source or sink mixed convection

In Vitro Antioxidant and Radio Protective Activities of Lycopene from Tomato Extract against Radiation—Induced DNA Aberration

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Journal of Biosciences and Medicines 2024年第2期12卷 202-213页

作者： Safaiatul islam Abu Hena Mostofa Kamal Md. Ziaur Rahman Protul Kumar Roy A.Y.K. Md. Masud Rana Molecular Radiobiology and Biodosimetry Division Institute of Food and Radiation Biology Bangladesh Atomic Energy Commission Savar Bangladesh

Background: The accumulation of free radicals is linked to a number of diseases. Free radicals can be scavenged by antioxidants and reduce their harmful effects. It is therefore essential to look for naturally occurring antioxidants that come from plants, as synthetic antioxidants are toxic, carcinogenic and problematic for the environment. Lycopene is one of the carotenoids, a pigment that dissolves in fat and has antioxidant properties. Materials and Methods: The antioxidant and free radical scavenging activity were assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The impact of lycopene on bacteria (E. coli) susceptibility to γ-radiation was examined by radio sensitivity assay. The study also examined the induction of strand breaks in plasmid pUC19 DNA and how lycopene extract protected the DNA from γ-radiation in vitro. Results: At varying concentrations, lycopene demonstrated its ability to scavenge free radicals such as 2, 2-diphenyl-1-picrylhydrazyl (DPPH). IC50 for lycopene was determined at 112 μg/mL which was almost partial to IC50 of standard antioxidant L-ascorbic acid. The D10 value 180 Gy of E. coli was found to be >2-fold higher in the extract-containing lycopene sample than in the extract-free controls. The lycopene extracts inhibited the radiation-induced deterioration of the plasmid pUC19 DNA. At an IC50 concentration, lycopene provided the highest level of protection. Conclusion: Lycopene functions as an efficient free radical scavenger and possible natural antioxidant source. For cancer patients and others who frequently expose themselves to radiation, lycopene may be a useful plant-based pharmaceutical product for treating a variety of diseases caused by free radicals.

关键词： Radio Protective Antioxidants Free Radical DNA Damage pUC19 Plasmid Gamma Irradiation DPPH

Optimal trajectory and heat load analysis of different shape lifting reentry vehicles for medium range application

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Defence Technology（防务技术） 2015年第4期11卷 350-361页

作者： S.Tauqeer ul islam RIZVI Lin-shu HE Da-jun XU School of Astronautics Beihang University

The objective of the paper is to compute the optimal burn-out conditions and control requirements that would result in maximum down-range/cross-range performance of a waverider type hypersonic boost-glide(HBG) vehicle within the medium and intermediate ranges,and compare its performance with the performances of wing-body and lifting-body vehicles vis-a-vis the g-load and the integrated heat load experienced by vehicles for the medium-sized launch vehicle under *** optimization studies were carried out by considering the heat rate and dynamic pressure *** trajectory optimization problem is modeled as a nonlinear,multiphase,constraint optimal control problem and is solved using a hp-adaptive pseudospectral *** modeling aspects of mass,aerodynamics and aerothermodynamics for the launch and glide vehicles have been *** was found that the optimal burn-out angles for waverider and wing-body configurations are approximately 5° and 14.8°,respectively,for maximum down-range performance under the constraint heat rate *** down-range and cross-range performance of HBG waverider configuration is nearly 1.3 and 2 times that of wing-body configuration *** integrated heat load experienced by the HBG waverider was found to be approximately an order of magnitude higher than that of a lifting-body configuration and 5 times that of a wing-body *** footprints and corresponding heat loads and control requirements for the three types of glide vehicles are discussed for the medium range launch vehicle under consideration.

关键词：再入飞行器载荷分析最佳轨迹翼身组合体形状最优控制问题控制要求运载火箭

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不同铜线芯直径超声波焊接头性能的研究

兵器材料科学与工程 2024年第5期47卷 8-12页

作者：沈中华张永祺赵伦龚涛梁召峰许龙周光平 Md Shafiqul islam 广西高校先进制造与自动化技术重点实验室广西桂林541006 深圳职业技术大学超声技术研究所广东深圳518055 瑞典布京理工学院机械学院布莱金厄卡尔斯克鲁纳37179

对3种不同的线芯直径的10 mm双铜(Cu)导线接头进行超声波焊接试验。通过剥离试验、孔隙率计算、温度测量、扫描电子显微镜(SEM)研究分析了铜导线接头性能和失效形式。结果表明:线芯直径与接头抗剥离力正相关,线芯直径越粗接头力学性能... 详细信息

对3种不同的线芯直径的10 mm双铜(Cu)导线接头进行超声波焊接试验。通过剥离试验、孔隙率计算、温度测量、扫描电子显微镜(SEM)研究分析了铜导线接头性能和失效形式。结果表明:线芯直径与接头抗剥离力正相关,线芯直径越粗接头力学性能越好。两根线芯直径为0.1 mm导线焊接的接头抗剥离强度未达标,失效形式为结合面完全分离无线芯断裂。直径增至0.2 mm时,接头抗剥离强度均达到标准,失效形式变为结合面处线芯的韧性断裂。焊接时的峰值温度有效影响了接头孔隙率,但孔隙率并不能完全作为判断接头成型质量的依据,部分导线在高温下仅发生塑性变形,而未能实现原子键合。此外,通过观察接头剖面发现,焊接接头形成了外紧内松的结构,与压块接触的接头上侧和与焊头接触的接头下侧几乎无空隙,而接头中间内侧则存在大量空隙。

关键词：超声波焊接铜导线力学行为断口形貌

Suggestion Mining from Opinionated Text of Big Social Media Data

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Computers, Materials & Continua 2021年第9期68卷 3323-3338页

作者： Youseef Alotaibi Muhammad Noman Malik Huma Hayat Khan Anab Batool Saif ul islam Abdulmajeed Alsufyani Saleh Alghamdi Department of Computer Science College of Computer and Information SystemsUmm Al-Qura UniversitySaudi Arabia Department of Computer Science Faculty of Engineering and Computer SciencesNational University of Modern LanguagesIslamabadPakistan Department of Software Engineering Faculty of Engineering and Computer SciencesNational University of Modern LanguagesIslamabadPakistan Department of Computer Sciences Institute of Space TechnologyIslamabadPakistan Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Information Technology College of Computers and Information TechnologyTaif UniversityTaifSaudi Arabia

:Social media data are rapidly increasing and constitute a source of user opinions and tips on a wide range of products and *** increasing availability of such big data on biased reviews and blogs creates challenges for customers and businesses in reviewing all content in their decision-making *** overcome this challenge,extracting suggestions from opinionated text is a possible *** this study,the characteristics of suggestions are analyzed and a suggestion mining extraction process is presented for classifying suggestive sentences from online customers’reviews.A classification using a word-embedding approach is used via the XGBoost *** two datasets used in this experiment relate to online hotel reviews and Microsoft Windows App Studio discussion reviews.F1,precision,recall,and accuracy scores are *** results demonstrated that the XGBoost classifier outperforms—with an accuracy of more than 80%.Moreover,the results revealed that suggestion keywords and phrases are the predominant features for suggestion ***,this study contributes to knowledge and practice by comparing feature extraction classifiers and identifying XGBoost as a better suggestion mining process for identifying online reviews.

关键词： Suggestion mining word embedding Naïve Bayes random forest XGBoost dataset

Variable-fidelity optimization with design space reduction

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Chinese Journal of Aeronautics 2013年第4期26卷 841-849页

作者： Mohammad Kashif zahir Gao Zhenghong School of Aeronautics Northwestern Polytechnical University

Advanced engineering systems, like aircraft, are defined by tens or even hundreds of design variables. Building an accurate surrogate model for use in such high-dimensional optimization problems is a difficult task owing to the curse of dimensionality. This paper presents a new algorithm to reduce the size of a design space to a smaller region of interest allowing a more accurate surrogate model to be generated. The framework requires a set of models of different physical or numerical fidelities. The low-fidelity （LF） model provides physics-based approximation of the high-fidelity （HF） model at a fraction of the computational cost. It is also instrumental in identifying the small region of interest in the design space that encloses the high-fidelity optimum. A surrogate model is then constructed to match the low-fidelity model to the high-fidelity model in the identified region of interest. The optimization process is managed by an update strategy to prevent convergence to false optima. The algorithm is applied on mathematical problems and a two-dimen-sional aerodynamic shape optimization problem in a variable-fidelity context. Results obtained are in excellent agreement with high-fidelity results, even with lower-fidelity flow solvers, while showing up to 39% time savings.

关键词： Airfoil optimization Curse of dimensionality Design space reduction Genetic algorithms Kriging Surrogate models Surrogate update strategies Variable fidelity

平板间方柱绕流的格子Boltzmann方法模拟

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哈尔滨工业大学学报 2010年第11期42卷 1753-1757页

作者：周超英葛家 islam Shams ul 哈尔滨工业大学深圳研究生院广东深圳518055

为研究平板间方柱绕流上下平板对置于其中的方柱绕流所产生的影响,采用格子Boltzmann方法对二维平板间低雷诺数(Re=100)方柱绕流问题进行了数值模拟研究.分析了3种不同阻塞比下,平板边壁对方柱的升、阻力系数、Strouhal数和尾涡流场的影... 详细信息

为研究平板间方柱绕流上下平板对置于其中的方柱绕流所产生的影响,采用格子Boltzmann方法对二维平板间低雷诺数(Re=100)方柱绕流问题进行了数值模拟研究.分析了3种不同阻塞比下,平板边壁对方柱的升、阻力系数、Strouhal数和尾涡流场的影响.结果表明:平板对方柱绕流特性有明显的影响,随着阻塞比的增加,阻力系数和Strouhal数均增大,与无边壁相比阻力系数可增加达30%,而升力系数却随之减小.计算结果与相关实验数据相吻合,验证了格子Boltzmann方法对钝体绕流非定常问题模拟的有效性。

关键词：格子Boltzmann方法方柱绕流壁面效应阻塞比