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World Journal of Gastroenterology 2007年第39期13卷 5226-5231页

作者： Mehmet zafer Sabuncuoglu Kemal Kismet Sibel Serin Kilicoglu Bulent Kilicoglu Serap Erel Sabahattin Muratoglu Asli Elif Sunay Esra Erdemli Mehmet Ali Akkus 4th General Surgery Department Ankara Training and Research Hospital Ulucanlar Ankara 06340 Turkey Department of Histology and EmbriologyUfuk University School of Medicine Ankara 06520 Turkey Microbiology Department Ankara Training and Research Hospital Ulucanlar Ankara 06340 Turkey Food Engineer Balparmak Pazarlama Cekmekoy 34760 Istanbul Turkey Department of Histology and Embriology Ankara University School of Medicine 06100 Ankara Turkey

AIM： To investigate the effects of propolis on bacterial translocation and ultrastructure of intestinal morphology in experimental obstructive jaundice. METHODS： Thirty Wistar-Albino male rats were randomly divided into three groups, each including 10 animals： group Ⅰ, sham-operated; group Ⅱ, ligation and division of the common bile duct （BDL）; group Ⅲ, BDL followed by oral supplementation of propolis 100 mg/kg per day. Liver, blood, spleen, mesenteric lymph nodes, and ileal samples were taken for microbiological, light and transmission electron microscopic examination on postoperative 7^th d after sacrification. RESULTS： The mean number of villi per centimeter and mean mucosal height of the propolis group were significantly different in the BDL group （P = 0.001 and 0.012, respectively）. The electron microscopic changes were also different between these groups. Sham and BDL＋propolis groups had similar incidence of bacterial translocation （BT）. The BDL group had significantly higher rates of BT as compared with sham and BDL ＋ propolis groups. BT was predominantly detected in MLNs and the most commonly isolated bacteria was Escherichia coil CONCLUSION： Propolis showed a significant protective effect on ileal mucosa and reduced bacterial translocation in the experimental obstructive jaundice model. Further studies should be carried out to explain the mechanisms of these effects,

关键词： Obstructive jaundice Bacterial translocation Ileal morphology

Importance and Risk Prediction of ABO Blood Group and Rh Factor in Papillary Thyroid Cancer

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Journal of Endocrinology Research 2022年第1期4卷 8-13页

作者： Dilek Geneş zafer Pekkolay MehmetŞimşek Hüsna Saraçoğlu Mehmet Turgut Alpaslan Kemal Tuzcu Dicle University Faculty of Medicine Department of Adult Endocrinology and MetabolismDiyarbakir21090Turkey

Objective:There are limited data in the literature regarding the potential relationship between thyroid cancer and ABO blood types and Rh *** aim of our study was to investigate whether papillary thyroid cancer(PTC)is associated with blood *** and Methods:The present study included patients who presented to Dicle University Faculty of Medicine between June 2009 and December 2020 and were diagnosed with PTC as a result of postoperative(thyroidectomy)histopathological *** control group consisted of individuals whose blood type was analyzed at a random blood ***:Of the 223 patients diagnosed with PTC,163(73.1%)were females and 60(26.9%)were *** the comparison of patients based on ABO blood types and Rh factor,A Rh positive blood type was found 31%less frequently in the PTC group compared with the control group,and thus it was associated with a lower risk of PTC(OR:0.69;95%Confidence Interval:0.50-0.96,p=0.029).Conclusions:In our study,we found A Rh positive blood type to be significantly less frequent among patients with PTC.A Rh positive blood type can be considered as a protective factor indicating a reduced risk of PTC.

关键词： Papillary thyroid cancer Blood types ABO Rh

Fractional Flow Reserve-Guided Lesion or Patient Management？

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Chinese Medical Journal 2015年第23期128卷 3266-3266页

作者： zafer Isilak Murat Yalcin Haluk Un Ejder Kardesoglu Department of Cardiology Gulhane Military Medical Academy Haydarpasa Training Hospital Istanbul Turkey

To the Editor： In one of the latest issues, Hu et al, carried out a national retrospective cohort study and investigated the clinical outcomes and cost of fractional flow reserve （FFR） guided percutaneous coronary intervention （PCI） in daily practice. FFR guided PCI was shown to improve the clinical outcomes with reduced cost, as demonstrated in the literature. We would like to expand the discussion part a little to figure out this issue more comprehensively.

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钽、铌、钛的表面特性与生物相容性

中国口腔种植学杂志 2013年第4期18卷 169-171页

作者：吴锋董兵辉 ALAJMI zafer 付涛西安交通大学医学院西安710061 西安交通大学生命科学与技术学院西安710061

目的:筛选心血管支架材料。方法:考察Ta、Nb、Ti的表面特性、血液相容性和内皮化能力。结果:Ta表面平整,Nb、Ti表面较为粗糙;三者均表现出弱的疏水性和良好的耐蚀性。三种试样的溶血率均低于5%,Ta表面粘附的血小板较少。内皮细胞培养3天... 详细信息

目的:筛选心血管支架材料。方法:考察Ta、Nb、Ti的表面特性、血液相容性和内皮化能力。结果:Ta表面平整,Nb、Ti表面较为粗糙;三者均表现出弱的疏水性和良好的耐蚀性。三种试样的溶血率均低于5%,Ta表面粘附的血小板较少。内皮细胞培养3天时,Ta表面的细胞增殖活性较好,而Nb表面的细胞生长较差。结论:Ta是一种良好的心血管支架材料。

关键词：钽铌钛腐蚀血液相容性内皮化

An independent prognostic factor for heart failure： sympathetic hyperactivity

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Chinese Medical Journal 2011年第7期124卷 1118-1118页

作者： Kardesoglu, Ejder Isilak, zafer Uz, Omer Yiginer, Omer Haydarpasa Training Hosp Gulhane Mil Med Acad Dept Cardiol Istanbul Turkey

To the editor： We read with attention the research article titled Long-term prognostic value of analysis of sympathetic drivewith dilated cardiomyopathy, and its prognostic value was assessed in a 54-month follow-up ... 详细信息

关键词： independent prognostic factor heart failure sympathetic hyperactivity

Caseous calcification of the mitral annulus： a rare variant of mitral annular calcification

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Chinese Medical Journal 2014年第16期127卷 3035-3035页

作者： Mehmet Dogan zafer Isilak Murat Atalay Omer Uz Department of Cardiology Gulhane Military Medical Academy Haydarpasa Training Hospital Istanbul 34668 Turkey Department of Cardiology Merzifon Military HospitalAmasya Turkey

To the editor： Mitral annular calcification （MAC） is a common echocardiographic iraage mostly seen in elderly women, found in almost 10% of the population over 50 years old. MAC describes a degenerative process of the mitral annulus, particularly involving the posterior mitral valve annulus. Caseous calcification of the mitral annulus （CCMA） is a rare variant of MAC, constituting 0.6% of all MAC cases. Herein we present a case of CCMA, which can be misdiagnosed as cyst, abscess or mass.

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The mechanisms of the relationship between glucocorticoids and cardiovascular diseases

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Chinese Medical Journal 2010年第23期123卷 3504-3504页

作者： Eider Kardesoglu zafer Isilak Omer Uz Turgay Celik Department of Cardiology Haydarpasa Training Hospital GulhaneMilitary Medical Academy Istanbul Turkey

To the editor： We have enjoyed reading an original article by Ji et al,1 entitled Influence of drug treatment on glucocorticoid receptor levels in patients with coronary heart disease, published in a recent issue of the Chinese Medical Journal. Herein, 80 patients with coronary artery disease were divided into four groups according to given drugs, and glucocorticoid （GC） receptor protein levels in peripheral blood lymphocytes were investigated before and I month after treatment in each group. In groups receiving beta blocker and nifedipine, increased levels were observed. They proposed that these increased levels might account for antiinflammatory effects of these drugs.

关键词：冠状动脉疾病内皮缩血管肽类气相色谱-质谱法受体糖皮质激素糖皮质激素类心血管疾病亚洲大陆世系人群药用制剂

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钽注入医用316L不锈钢的表面结构与性能

中国材料科技与设备 2013年第6期9卷 30-32页

作者：付涛 ALAJMI zafer 董兵辉马胜歌西安交通大学生命科学与技术学院陕西西安710049 深圳八六三计划材料表面技术研发中心广东深圳518029

采用钽离子注入对医用316L不锈铜进行表面改性，并以镍钛合金作为对照。钽注入后316L试样的表面形貌没有发生明显变化．而镍钛合金表面形成了纳米结构。X射线光电子能谱分析在注入试样的外表面层和基体较大的深度内检测到Ta2O5、TaC和金... 详细信息

采用钽离子注入对医用316L不锈铜进行表面改性，并以镍钛合金作为对照。钽注入后316L试样的表面形貌没有发生明显变化．而镍钛合金表面形成了纳米结构。X射线光电子能谱分析在注入试样的外表面层和基体较大的深度内检测到Ta2O5、TaC和金属Ta。水接触角测量表明钽注入后两种材料变得更为疏水（接触角大于95°）。在0．9％NaCI溶液中的动电位极化测试表明，注入后两种材料的耐蚀性均提高．但由于改性层厚度有限．316L试样的耐蚀性仍然较弱。

关键词：不锈钢钽离子注入亲水性耐蚀性

Ischemic conditioning： a current concept in reducing reperfusion injury

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Chinese Medical Journal 2011年第3期124卷 480-480页

作者： Ejder Kardesoglu zafer lsilak Omer Uz Omer Yiginer Department of Cardiology Gulhane Military Medical AcademyHaydarpasa Training Hospital lstanbul Turkey

To the editor： We read with great enthusiasm an interesting and exciting research article by Lin et al,1 who studied two different postconditioning protocols applied four times for 30 and 60 seconds. They compared with each other in terms of its effect on tumor necrosis factor-α （TNF-α） levels as well as on the echocardiographic parameters. They concluded that the 60-second postconditioning prevented the increase of TNF-α on the seventh day with the long-term cardiac protection.

关键词： a current reducing reperfusion cardiac protection