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Medicinal Plants Used in Management of Various Mental Illnesses in Goma City, Democratic Republic of Congo

Neuroscience & Medicine 2022年第1期13卷 17-42页

作者： Samuel Kule Kyolo Esther Katuura Godfrey Bbosa Norah Mwebaza zacharie tsongo kibendelwa Noeline Nakasujja Department of Pharmacology and Therapeutics School of Biomedical Sciences College of Health Sciences Mekerere University Kampala Uganda Department of Plant Sciences Microbiology and Biotechnology School of Biological Sciences College of Natural Sciences Makerere University Kampala Uganda Department of Internal Medicine Faculty of Human Medicine University of Goma (UNIGOM) Democratic Republic of Congo Department of Psychiatry School of Medicine College of Health Sciences Makerere University Kampala Uganda

Many mentally ill people in Goma city, Democratic Republic of Congo (DRC), seek treatment from Traditional Health Practitioners (THPs) that utilize medicinal plants (MPs) in management of various ailments. The study aimed to document the MPs used locally to manage mental illnesses (MIs). An in-depth ethnobotanical survey including 43 respondents selected using snow ball method and interviewed using semi-structured questionnaires was conducted in Goma city, in DRC, from May to September 2021. Voucher specimens were collected from the study area and identified at Makerere University Herbarium (MHU). Data were analyzed using ethnobotanical parameters, frequency index, Rahman’s similarity index (RSI) and non-parametric tests as well as Spearman correlation coefficient. A total of 30 plant species, represented amongst 29 genera and 19 families were reportedly used to treat MIs. Of these 63.33% were reported for anxiety, 36.67% for psychosis and 30% for depression. Most abundant taxa were reported for three families including Asteraceae, Lamiaceae and Solanaceae. Among MPs used in Goma city, the two priority plant species for anxiety were Euphorbia abyssinica and Cleome gynandra L. While, the two priority plant species for depression were Conyza sumatrensis and Emilia coccinea. High similarity (RSI = 77.42%) was observed in the use of common species for MIs between THPs from both Goma and Karisimbi communes. Results prove that local people of Goma city use MPs species against MIs that could be further studied for pharmacological effectiveness and safety.

关键词： Medicinal Plants Indigenous Management Mental Illnesses

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Performance of the Peguero-Lo Presti Index in Diagnosis of Left Ventricular Hypertrophy at CIMAK Hospital Center in North Kivu, Democratic Republic of the Congo

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World Journal of Cardiovascular Surgery 2023年第2期13卷 11-25页

作者： Ferdinand Ng’ekieb Mukoso Aliocha Natuhoyila Nkodila Thierry-Samuel Mbuyi Muhemed Trésor Mosomo Kashinde Sévérin Juamungu Ananas Salomo Ndoole Myatsi Ariane Namwiza Gakuru Olivier Gasana Muratwa Zéphirin Tudienzelz Kamuanga Yves Lubenga Bernard Phanzu Kianu Benjamin Longo-Mbenza zacharie kibendelwa tsongo Department of Health Sciences Higher Institute of Medical Techniques of Bandundu Bandundu Democratic Republic of Congo Faculty of Medicine University of Goma Goma Democratic Republic of Congo Service of Cardiology International Clinic for Advanced Medicine in Kivu Goma Democratic Republic of Congo Department of Family Medicine and Primary Health Care Protestant University of Congo Kinshasa Democratic Republic of Congo Faculty of Medicine University of Joseph Kasavubu Boma Democratic Republic of Congo Department of Health Sciences National Pedagogical University Kinshasa Democratic Republic of Congo Department of Cardiology University of Kinshasa Kinshasa Democratic Republic of Congo

Background and Objective: Despite the costs generated in the diagnosis of cardiac pathologies by the use of ultrasound, the ECG indices have demonstrated a high performance in the studies of developed countries in the diagnosis of these pathologies, but the data of these in sub-Saharan Africa are limited. The objective of this study is to evaluate the performance of the Peguero-Lo Presti index in the diagnosis of LVH among Congolese in order to make it a means of LVH diagnosis in an under-equipped environment. Methods: Cross-sectional and analytical study including 413 patients followed and hospitalized at the CIMAK Hospital Center during the period from February 2019 to June 2021. Sociodemographic parameters, history, biology, ultrasound and ECG parameters were studied. The performance of the Peguero-Lo Presti Index was validated by the Youden Index reinforced by the Area under the ROC curve. Results: Of the 413 patients admitted to the study, 69.5% were men versus 30.5% women, i.e. a sex ratio of 2M/1F;the mean age of the patients was 51.1 ± 11.6 years. The frequency of LVH found by echocardiography was 55.9%, it was 50.8% using the Peguero-Lo Presti index, 22% and 10.2% using the Peguero-Lo Presti index, respectively. Sokolow-Lyon and Cornell (p 0.001). The Peguero-Lo Presti curve is higher than the Sokolow-Lyon and Cornell curves. The area under the curve was 0.80 for Peguero-Lo Presti, 0.73 for Sokolow-Lyon and 0.66 for cornell. Conclusion: The newly proposed Peguero-Lo Presti index provides high sensitivity and specificity for the diagnosis of LVH in black Africans as also reported in the European and American population.

关键词： Performance Peguero-Lo Presti ECG Sokolow-Lyon Cornell DRC

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Performance of the Peguero-Lo Presti Index in Diagnosis of Left Ventricular Hypertrophy at CIMAK Hospital Center in North Kivu, Democratic Republic of the Congo

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World Journal of Cardiovascular Surgery（心血管外科国际期刊） 2023年第2期

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