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Fractal model of spontaneous imbibition in low-permeability reservoirs coupled with heterogeneity of pore seepage channels and threshold pressure

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Petroleum Science 2024年第2期21卷 1002-1017页

作者： Ming-sheng zuo Hao Chen Xi-Liang Liu Hai-peng Liu Yi Wu Xin-Yu Qi National Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China College of Safety and Ocean Engineering China University of Petroleum(Beijing)Beijing102249China

Spontaneous imbibition(SI)is an important mechanism for enhancing oil recovery in low-permeability *** to the strong heterogeneity,and the non-Darcy flow,the construction of SI model for lowpermeability reservoirs is extremely ***,traditional SI models based on single or averaged capillary tortuosity ignore the influence of heterogeneity of pore seepage channels and the threshold pressure(TP)on ***,in this work,based on capillary model and fractal theory,a mathematical model of characterizing SI considering heterogeneity of pore seepage channels is *** this basis,the threshold pressure was introduced to determine the pore radius at which the wetted phase can displace *** proposed new SI model was verified by imbibition experimental *** study shows that for weakly heterogeneous cores with permeability of 0-1 m D,the traditional SI model can characterize the imbibition process relatively accurately,and the new imbibition model can increase the coefficient of determination by 1.05 ***,traditional model has serious deviations in predicting the imbibition recovery for cores with permeability of 10-50 m *** new SI model coupling with heterogeneity of pore seepage channels and threshold pressure effectively solves this problem,and the determination coefficient is increased from 0.344 to 0.922,which is increased by2.68 *** low-permeability reservoirs,the production of the oil in transitional pores(0.01-0.1μm)and mesopores(0.1-1μm)significantly affects the imbibition recovery,as the research shows that when the heterogeneity of pore seepage channels is ignored,the oil recovery in transitional pores and mesopores decreases by 7.54%and 4.26%,*** analysis shows that increasing interfacial tension,decreasing contact angle,oil-water viscosity ratio and threshold pressure will increase imbibition *** addition,there are critical values for the influence of these factors o

关键词： Spontaneous imbibition Low-permeability reservoir Fractal model Threshold pressure Capillary tube

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New perspectives in free nitrous acid (FNA) uses for sustainable wastewater management

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Frontiers of Environmental Science & Engineering 2024年第2期18卷 161-168页

作者： Zhiqiang zuo Min Zheng Tao Liu Yongzhen peng Zhiguo Yuan National Engineering Laboratory for Advanced Municipal Wastewater Treatment and Reuse Technology Engineering Research Center of BeijingBeijing University of TechnologyBeijing 100124China Australian Centre for Water and Environmental Biotechnology The University of QueenslandSt.LuciaQLD 4072Australia Water Research Centre School of Civil and Environmental EngineeringUniversity of New South WalesSydneyNew South Wales 2052Australia Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong 999077China School of Energy and Environment City University of Hong KongHong Kong 999077China

The biocidal effects of free nitrous acid (FNA) have found applications in multiple units in an urban wastewater system, including sewer networks, wastewater treatment processes, and sludge treatment processes. However, these applications are associated with chemical costs as both nitrite and acid are needed to produce FNA at the required levels. The recent discovery of novel acid-tolerant ammonia oxidizers offers the possibility to produce FNA from domestic wastewater, enabling the development of next-generation FNA-based technologies capable of achieving self-sustaining FNA production. In this study, we focus on the concept of in situ FNA generation facilitated by acid-tolerant ammonia oxidizers and highlight the multiple benefits it creates, after a brief review of the historical development of FNA-based technologies. We will discuss how wastewater systems can be made more energy-efficient and sustainable by leveraging the potential of acid-tolerant ammonia oxidizers.

关键词： Free nitrous acid Acid-toler antammonia oxidizer In situ generationl Wastewater management

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Wireless electrical stimulation generated by piezoelectric nanomaterial promotes the dental pulp regeneration via regulating mitochondrial Ca^(2+)/PKA signaling pathway

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Journal of Materials Science & Technology 2024年第1期168卷 24-34页

作者： Jianmao Zheng Jiyuan zuo Cairong Xiao Qining Guo Xiaobin Fu Chengyun Ning peng Yu Guangdong Provincial Key Laboratory of Stomatology Hospital of StomatologySun Yat-Sen UniversityGuangzhou 510080China School of Materials Science and Engineering National Engineering Research Center for Tissue Restoration and ReconstructionSouth China University of TechnologyGuangzhou 510641China

The induction of dental pulp stem cells(DPSCs)into odontogenic differentiation is a cutting-edge method of dental pulp regeneration ***,it remains a challenge to develop biomaterials and ther-apies that can induce odontogenic ***,we propose a wireless electrical stimulation strat-egy to induce DPSCs odontogenic differentiation via K_(0.5)Na_(0.5)NbO_(3)piezoelectric nanoparticles(KNN)and polarized KNN(PKNN),which can be endocytosed by *** vitro,several odontogenic differentiation indexes were also increased in DPSCs treated with KNN and PKNN,and the increase was more obvious in the PKNN *** wireless electrical field promoted mitochondrial calcium concentration via mitochondrial calcium unidirectional transporter(MCU),increased the production of adenosine triphos-phate(ATP),and induced odontogenic differentiation through the activation of the cAMP-PKA signaling *** vivo,dental pulp-like tissue was induced by electrical stimulation wirelessly with KNN and PKNN,which was more clinically friendly compared with the wired device,and the induction was more obvious in the PKNN group consistent with in vitro *** conclusion,this work demonstrates the potential of PKNN as an effective stimulus that can induce odontogenic differentiation of DPSCs and be applied to dental pulp regeneration treatment.

关键词： Piezoelectric nanoparticles Dental pulp stem cells Odontogenic differentiation

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Numerical study on influence of protrusion heights on Reynolds stress and viscous stress variations in turbulent vortical structures

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Chinese Journal of Aeronautics 2024年第9期37卷 59-71页

作者： Zhiping LI Long HE Jingsai ZHOU Yueren zuo Yao YIN peng ZHANG Bo MENG Research Institute of Aero-Engine Beihang UniversityBeijing 100191China School of Energy and Power Engineering Beihang UniversityBejing 100191China Institute of Acoustics Chinese Academy of SciencesBeijing 100190China College of Aeronautical Engineering Civil Aviation University of ChinaTianjin 300300China AECC Hunan Aviation Powerplant Research Institute Zhuzhou 412002China

Analysing the infuence mechanism of the riblet protrusion height on turbulent drag components is more beneficial in organising the vortical structure over the riblet ***,the Large Eddy Simulation(LES)is used to investigate the vortex structure over the rib-let surface with different protrusion ***,the variations of Reynolds stress and viscous shear stress in a turbulent channel are *** a result,the drag reduction rate increases from 3.4%when the riblets are completely submerged in the turbulent boundary layer to 7.9%when the protrusion height is *** analysis shows that the protrusion height affects the streamwise vortices and the normal diffusivity of spanwise and normal vortices,thus driving the variation of Reynolds *** with the smooth surface,the vorticity strength and the number of streamwise vortices are weakened near the wall but increase in the logarithmic layer with increased protrusion ***,the normal diffusivity of spanwise vorticity decreases with the increase of protrusion height,and the normal diffusivity of normal vorticity is the smallest when the protrusion height is ***,the protrusion height affects the velocity gradient of the riblet tip and riblet valley,thus driving the variation of viscous shear *** the increase of protrusion height,the velocity gradient of the riblet tip increases dramatically but decreases in the riblet valley.

关键词： Riblet Dragreduction Protrusion height Vortical structure Vortexdiffusivity Reynolds stress Viscous stress

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A layered multifunctional framework based on polyacrylonitrile and MOF derivatives for stable lithium metal anode

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Journal of Energy Chemistry 2024年第6期93卷 282-288,I0007页

作者： Fanfan Liu peng zuo Jing Li pengcheng Shi Yu Shao Linwei Chen Yihong Tan Tao Ma Engineering Research Center of High-frequency Soft Magnetic Materials and Ceramic Powder Materials of Anhui Province School of Chemistry and Material EngineeringChaohu UniversityHefei 238024AnhuiChina Frontiers Science Center for Transformative Molecules School of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240China School of Pharmacy Anhui University of Chinese MedicineHefei 230012AnhuiChina School of Materials and Energy Guangdong University of TechnologyGuangzhou 510006GuangdongChina Jiujiang DeFu Technology Co. Ltd.Jiujiang 332000JiangxiChina

Composite Li metal anodes based on three-dimensional(3D) porous frameworks have been considered as an effective material for achieving stable Li metal batteries with high energy ***,uneven Li deposition behavior still occurs at the top of 3D frameworks owing to the local accumulation of Li *** promote uniform Li deposition without top dendrite growth,herein,a layered multifunctional framework based on oxidation-treated polyacrylonitrile(OPAN) and metal-organic framework(MOF) derivatives was proposed for rationally regulating the distribution of Li ions flux,nucleation sites,and electrical *** from these merits,the OPAN/carbon nano fiber-MOF(CMOF) composite framework demonstrated a reversible Li plating/stripping behavior for 500 cycles with a stable Coulombic efficiency of around 99.0% at the current density of 2 mA/cm~***,such a Li composite anode exhibited a superior cycle lifespan of over 1300 h under a low polarized voltage of 18 mV in symmetrical *** the Li composite anode was paired with LiFePO_(4)(LFP) cathode,the obtained full cell exhibited a stable cycling over 500 ***,the COMSOL Multiphysics simulation was conducted to reveal the effects on homogeneous Li ions distribution derived from the above-mentioned OPAN/CMOF framework and electrical insulation/conduction *** electrochemical and simulated results shed light on the difficulties of designing stable and safe Li metal anode via optimizing the 3D frameworks.

关键词： Lithium metal anode Layered multifunctional framework Ions flux redistribution Electrical insulation/conduction structure Uniform Li deposition

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Progress and prospects of pH-neutral aqueous organic redox flow batteries:Electrolytes and membranes

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Journal of Energy Chemistry 2024年第9期96卷 89-109页

作者： Kang peng Gonggen Tang Chao Zhang Xian Yang Peipei zuo Zhanfeng Xiang Zhong Yao Zhengjin Yang Tongwen Xu Key Laboratory of Precision and Intelligent Chemistry Department of Applied ChemistrySchool of Chemistry and Materials ScienceUniversity of Science and Technology of ChinaHefei 230026AnhuiChina Suqian Time Energy Storage Technology Co. Ltd.Suqian 223800JiangsuChina

Aqueous organic redox flow batteries(AORFBs),which exploit the reversible electrochemical reactions of water-soluble organic electrolytes to store electricity,have emerged as an efficient electrochemical energy storage technology for the grid-scale integration of renewable ***-neutral AORFBs that feature high safety,low corrosivity,and environmental benignity are particularly promising,and their battery performance is significantly impacted by redox-active molecules and ion-exchange membranes(IEMs).Here,representative anolytes and catholytes engineered for use in pH-neutral AORFBs are outlined and summarized,as well as their side reactions that cause irreversible battery capacity *** addition,the recent achievements of IEMs for pH-neutral AORFBs are discussed,with a focus on the construction and tuning of ion transport ***,the critical challenges and potential research opportunities for developing practically relevant pH-neutral AORFBs are presented.

关键词： Aqueous organic redox flow battery pH-Neutral Anolyte Catholyte Membrane

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Regulatory RNAs in Bacillus subtilis:A review on regulatory mechanism and applications in synthetic biology

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Synthetic and Systems Biotechnology 2024年第2期9卷 223-233页

作者： Anqi peng Guobin Yin Wenjie zuo Luyao Zhang Guocheng Du Jian Chen Yang Wang Zhen Kang The Science Center for Future Foods Jiangnan UniversityWuxi214122China The Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxi214122China The Key Laboratory of Industrial Biotechnology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxi214122China

Bacteria exhibit a rich repertoire of RNA molecules that intricately regulate gene expression at multiple hierarchical levels,including small RNAs(sRNAs),riboswitches,and antisense ***,the majority of these regulatory RNAs lack or have limited protein-coding capacity but play pivotal roles in orchestrating gene expression by modulating transcription,post-transcription or translation *** and redesigning these regulatory RNA elements have emerged as pivotal strategies in the domains of metabolic engineering and synthetic *** previous investigations predominantly focused on delineating the roles of regulatory RNA in Gram-negative bacterial models such as Escherichia coli and Salmonella enterica,this review aims to summarize the mechanisms and functionalities of endogenous regulatory RNAs inherent to typical Gram-positive bacteria,notably Bacillus ***,we explore the engineering and practical applications of these regulatory RNA elements in the arena of synthetic biology,employing *** as a foundational chassis.

关键词： Regulatory RNA devices Small RNAs Riboswitches Synthetic biology Bacillus subtilis

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Giant reversible barocaloric effects with high thermal cycle stability in epoxybonded(MnCoGe)_(0.96)(CuCoSn)_(0.04) composite

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International Journal of Minerals,Metallurgy and Materials 2024年第11期31卷 2528-2534页

作者： Yafei Kuang Kun Tao Bo Yang peng Tong Yan Zhang Zhigang Sun Kewei Zhang Dunhui Wang Jifan Hu Liang zuo College of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024China Shanxi Key Laboratory of Magnetic and Electric Functional Materials and Applications Taiyuan University of Science and TechnologyTaiyuan 030024China Key Laboratory of Materials Physics Institute of Solid State PhysicsChinese Academy of SciencesHefei 230031China Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education) School of Materials Science and EngineeringNortheastern UniversityShenyang 110819China School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China

Hexagonal MnMX-based(M=Co or Ni,X=Si or Ge)alloys exhibit giant reversible barocaloric ***,giant volume expansion would result in the as-cast MnMX ingots fragmenting into powders,and inevitably bring the deterioration of mechanical properties and *** fragmentation can bring degradation of structural transformation entropy change during cyclic application and removal of *** this paper,giant reversible barocaloric effects with high thermal cycle stability can be achieved in the epoxy bonded(MnCoGe)0.96(CuCoSn)0.04 *** reversible isothermal entropy change of 43.0 J·kg^(−1)·K^(−1) and adiabatic temperature change from barocaloric effects(ΔT_(BCE))of 15.6 K can be obtained within a wide temperature span of 30 K at 360 MPa,which is mainly attributed to the integration of the change in the transition temperature driven by pressure of−101 K·GPa^(−1) and suitable thermal hysteresis of 11.1 ***,the variation of reversibleΔ_(TBCE) against the applied hydrostatic pressure reaches up to 43 K·GPa^(−1),which is at the highest level among the other reported giant barocaloric *** importantly,after 60 thermal cycles,the composite does not break and the calorimetric curves coincide well,demonstrating good thermal cycle stability.

关键词： barocaloric effects cycle stability reversible isothermal entropy change reversible adiabatic temperature change MnCoGe alloys

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Development of Machine Learning Methods for Accurate Prediction of Plant Disease Resistance

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Engineering 2024年第9期40卷 100-110页

作者： Qi Liu Shi-min zuo Shasha peng Hao Zhang Ye peng Wei Li Yehui Xiong Runmao Lin Zhiming Feng Huihui Li Jun Yang Guo-Liang Wang Houxiang Kang State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Zhongshan Biological Breeding Laboratory&Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding Agricultural College of Yangzhou UniversityYangzhou 225009China Hunan Provincial Key Laboratory of Crop Germplasm Innovation and Utilization and College of Agronomy Hunan Agricultural UniversityChangsha 410128China State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China College of Plant Protection Hunan Agricultural UniversityChangsha 410128China Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests Ministry of Education College of Plant ProtectionHainan UniversityHaikou 570228China MARA Key Laboratory of Surveillance and Management for Plant Quarantine Pests Department of Plant BiosecurityCollege of Plant ProtectionChina Agricultural UniversityBeijing 100193China Department of Plant Pathology Ohio State UniversityColumbusOH 43210USA

The traditional method of screening plants for disease resistance phenotype is both time-consuming and *** selection offers a potential solution to improve efficiency,but accurately predicting plant disease resistance remains a *** this study,we evaluated eight different machine learning(ML)methods,including random forest classification(RFC),support vector classifier(SVC),light gradient boosting machine(lightGBM),random forest classification plus kinship(RFC_K),support vector classification plus kinship(SVC_K),light gradient boosting machine plus kinship(lightGBM_K),deep neural network genomic prediction(DNNGP),and densely connected convolutional networks(DenseNet),for predicting plant disease *** results demonstrate that the three plus kinship(K)methods developed in this study achieved high prediction ***,these methods achieved accuracies of up to 95%for rice blast(RB),85%for rice black-streaked dwarf virus(RBSDV),and 85%for rice sheath blight(RSB)when trained and applied to the rice diversity panel I(RDPI).Furthermore,the plus K models performed well in predicting wheat blast(WB)and wheat stripe rust(WSR)diseases,with mean accuracies of up to 90%and 93%,*** assess the generalizability of our models,we applied the trained plus K methods to predict RB disease resistance in an independent population,rice diversity panel II(RDPII).Concurrently,we evaluated the RB resistance of RDPII cultivars using spray *** the predictions with the spray inoculation results,we found that the accuracy of the plus K methods reached 91%.These findings highlight the effectiveness of the plus K methods(RFC_K,SVC_K,and lightGBM_K)in accurately predicting plant disease resistance for RB,RBSDV,RSB,WB,and *** methods developed in this study not only provide valuable strategies for predicting disease resistance,but also pave the way for using machine learning to streamline genome-based crop breeding.

关键词： Predicting plant disease resistance Genomic selection Machine learning Genome-wide association study

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Analysis of large datasets for identifying molecular targets in intestinal polyps and metabolic disorders

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BIOCELL 2024年第3期48卷 415-429页

作者： SHAN OU YUN XU QINGLAN LIU TIANWEN YANG WEI CHEN XIU YUAN XIN zuo peng SHI JIE YAO Department of Gastroenterology The First Affiliated Hospital of Chongqing Medical and Pharmaceutical CollegeChongqingChina

Background:The interrelation between intestinal polyps,metabolic syndrome(MetS),and colorectal cancer(CRC)is a critical area of *** research focuses on pinpointing potential molecular targets to understand the link between intestinal polyp formation,metabolic irregularities,and CRC ***:We examined clinical samples from patients with intestinal polyps coexisting with MetS and compared them with samples from patients with standard intestinal *** sequencing and public database analysis were employed to identify significant pathways and *** targets were then validated through immunohistochemistry(IHC).Following the RNA interference of key target expression,a series of experiments,including the cell counting kit-8 assay,colony formation,wound healing,and Transwell assays,were ***:Comparative analysis revealed 75 up-regulated and 61 down-regulated differentially expressed genes(DEGs)in the MetS polyp group *** *** encyclopedia of genes and genomes(KEGG)pathway enrichment suggested these DEGs were primarily associated with cell cycle and *** with comparative toxicogenomics database(CTD)and the cancer genome atlas(TCGA)databases highlighted 44 key CRC-related *** interaction networks indicated connections of purkinje cell protein 4(PCP4),olfactomedin 1(OLFM1),fibronectin 1(FN1),and transforming growth factor beta 3(TGF-β3)with the mitogen-activated protein kinase(MAPK)*** correlation studies suggested higher risk associations with FN1,PCP4,and TGF-β3,while OLFM1 was identified as a lower risk *** analysis revealed a decrease in OLFM1 in MetS-associated intestinal *** interference with OLFM1 in polyp epithelial cells,there was a significant enhancement in cell proliferation,colony formation,and cell migration and invasion ***:Our study highlights a significant decrease in OLFM1 expression in MetS-associated intestinal

关键词： Colorectal cancer Metabolic syndrome Intestinal polyp OLFM1 Exosome

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