检索结果-南通市图书馆

Effect of Pathoanatomic Diagnosis on the Quality of Birth Defects Surveillance in China

Biomedical and Environmental Sciences 2009年第6期22卷 464-471页

作者： LI-JUN PEI GONG CHEN XIN-MING SONG JI-LEI WU CHENG-FU LI JI-ZHEN zou jiu-ZHI LIN TING ZHANG XIAO-YING ZHENG Institute of Population Research/WHO Collaborating Center on Reproductive Health and Population Science Peking University Beijing 100871 China Capital Institute of Pediatrics Beijing 100020 China

Objective To provide evidence for more accurate diagnosis of birth defects based on the pathoauatomy of congenital malformations. Methods Data used in this study were obtained fi＇om Luliang City Hospital and three county hospitals of Shanxi province between February 2004 and March 2006. Autopsy and pathological examination of 160 dead fetuses and stillbirths were performed. Photos of dead fetuses and stillbirths were taken, tissues were cut into sections for pathological examination under microscope, all pathological information was recorded, and percentage of birth defects was calculated. Results The proportion of dead fetuses and stillbirths with or without congenital malformations was 84.4% （135/160） and 15.6% （25/160）, respectively. There were 16 categories of major external and internal birth defects in 135 cases of such defects. Congenital heart defects, anencephaly and spina bifida had a higher prevalence rate in the study period. The prevalence rate of non-malformation death and birth defects 〈 28 gestational weeks and internal anomalies ≥ 28 gestational weeks was 14.61% （61/4175） and 17.25% （72/4175）, respectively. A total of 413 in situ anomalies were found in 135 cases of autopsy. Spina bifida, anencephaly, congenital heart defects, aplasia or accessory lobe of lung, renal agenesis and dysplasis and congenital hydrocephaly were more closely associated with severe malformations than with mitis malformations. The cases of dead fetuses and stillbirths with multiple malformations （/〉 2 in situ anomalies） had a higher proportion （74.1%）, whereas those with isolated malformations had a lower proportion （25.93%）. Conclusion The occurrence of congenital malformations in different embryonic developmental stages affects multiple organs. Postmortem examination of internal and multiple malformations of fetal deaths and stillbirths can provide more accurate diagnostic information for birth defects.

关键词： Birth defects Pathoanatomy Congenital internal anomaly Congenital external anomaly ICD-10 codes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Methods for Shale Gas Play Assessment: A Comparison between Silurian Longmaxi Shale and Mississippian Barnett Shale

引用

Journal of Earth Science 2015年第2期26卷 285-294页

作者： Songqi Pan Caineng zou Zhi Yang Dazhong Dong Yuman Wang Shufang Wang Songtao Wu Jinliang Huang qun Liu Dule Wang Ziyuan Wang School of Earth and Space Sciences Peking University Research Institute of Petroleum Exploration & Development Petro China Southwest Petroleum University

Based on field work, organic geochemical analyses and experimental testing, a six-property assessment method for shale gas is proposed. These six properties include organic matter properies, lithofacies, petrophysical properties, gas content, brittleness and local stress field. Due to the features of continuous distribution over a large area and low resource abundance in shale plays, a sweet spot should have these following properties：（a） TOC〉2%; （b） brittle minerals content （〉40%） and clay minerals （〈30%）; （c） Ro （〉1.1%）; （d） porosity （〉2%） and permeability （〉0.000 1 mD）, and （e） effective thickness （30-50 m）. Applying these criteria in the Sichuan Basin, the Silurian Longmaxi shale consists of four prospecting sweet spots, including blocks of Changning, Weiyuan, Zhaotong and Fushnn-Yongchuan. Although these four blocks have some similarities, different features were usually observed. After comprehensive analyses using the six-property assessment method, the Fushun-Yongan Block ranks the most favorable sweet spot, followed by the Weiyuan Block. For the other two blocks, the Changning Block is better than the Zbaotong Block. By comparing with the Mississippian Barnett shale, characteristics that are crucial for a high-yielding in the Sichuan Basin include a high content of organic matter （TOC〉2.5%）, a moderate thermal maturity （Ro=0.4%-2%）, a high content of brittle minerals （quartz： 30%-45%）, a high gas content （〉2.5 m^3·t^-1）, and types I and II1 kerogen.

关键词： shale gas play Silurian Longmaxi shale Barnett shale sweet spot six-property assessment.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Simultaneous determination of metronidazole and tinidazole in plasma by using HPLC-DAD coupled with second-order calibration

引用

Chinese Chemical Letters 2010年第10期21卷 1223-1226页

作者： Li qun Ouyang Hai Long Wu Ya Juan Liu Jian Yue Wang Yong Jie Yu Hong Yan zou Ru Qin Yu State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University Changsha 410082 China Zhoushan Municipal Center for Disease Control & Prevention Zhoushan 310062 China

A method using HPLC-DAD coupled with second-order calibration was developed to simultaneously determine metronidazole and tinidazole in plasma samples in this paper. The second-order calibration method based on APTLD （alternating penalty trilinear decomposition） algorithm was proposed to analyze the three-way HPLC-DAD data from both standard and prediction samples, which makes it possible that calibration can be performed even in the presence of unknown interferences with a simple and green chromatographic condition and short analysis time. The results showed that good recoveries were obtained although the chromatographic and spectral profiles of the analytes of interest as well as background were partially overlapped with each other in plasma samples.

关键词： HPLC-DAD Second-order calibration Alternating penalty trilinear decomposition (APTLD) Metronidazole Tinidazole Plasma

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

临床护士为终末期患者实施本土化叙事护理的体验

引用

中国护理管理 2024年第2期24卷 181-186页

作者：王丹陈群王艳波张金梅李贤慧邹莉萍杜玉虹蒲世娟王海燕李扬会徐州医科大学附属医院肿瘤内科江苏省徐州市221006 厦门大学附属心血管病医院冠心病监护室同济大学医学院海军军医大学第一附属医院呼吸内科晋城市第二人民医院普外科邛崃市医疗中心医院肿瘤科厦门大学附属中山医院妇产科宜宾市第二人民医院血液科南充市中心医院护理部聊城市人民医院全科医学科

目的:了解临床护士结合中国传统文化为终末期患者实施叙事护理的体验,为本土化叙事护理的临床推广提供参考。方法:采用滚雪球抽样法,选取12名为终末期患者实施过叙事护理的临床护士进行半结构式访谈,采用主题分析法分析资料。结果:为终... 详细信息

目的:了解临床护士结合中国传统文化为终末期患者实施叙事护理的体验,为本土化叙事护理的临床推广提供参考。方法:采用滚雪球抽样法,选取12名为终末期患者实施过叙事护理的临床护士进行半结构式访谈,采用主题分析法分析资料。结果:为终末期患者实施本土化叙事护理的过程中,临床护士的体验包括临床变革、实践历程、自我获益、困境与挑战4个主题。结论:通过对终末期患者实施本土化叙事护理,既缓解了临终患者的痛苦,也提升了护士的职业价值感,但叙事护理实践也面临着较多的挑战,需要来自管理层及组织层面的支持,以确保本土化叙事护理实践的可持续发展。

关键词：本土化叙事护理临床护士终末期患者安宁疗护质性研究

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unsaturated-sulfur-rich MoS2 nanosheets decorated on free-standing SWNT film： Synthesis, characterization and electrocatalytic application

引用

Nano Research 2016年第7期9卷 2079-2087页

作者： Daobin Liu Weiyu Xu Qin Liu qun He Yasir A. Haleem Changda Wang Ting Xiang Chongwen zou Wangsheng Chu Jun Zhong Zhiqiang Niu Li Song National Synchrotron Radiation Laboratory CAS Hefei Science Center University of Science and Technology of China Hefei 230029 China jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Institute of Functional Nano & Soft Materials Laboratory (FUNSOM) Soochow University Suzhou 215123 China Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) College of Chemistry Collaborative Innovation Center of Chemical Science and Engineering Nankai University Tianjin 300071 China

Herein, we report a bottom-up solvothermal route to synthesize a flexible, highly efficient MoS2@SWNT electrocatalyst for hydrogen evolution reactions （HER）. Characterization revealed that branchqike MoS2 nanosheets containing sulfur- rich sites were in situ uniformly dispersed on free-standing single-walled carbon nanotube （SWNT） film, which could expose more unsaturated sulfur atoms, allowing excellent electrical contact with active sites. The flexible catalyst exhibited excellent HER performance with a low overpotential （-150 mV at 10 ma/cm2） and small Tafel slope （4l mV/dec）. To further explain the improved performance, the local electronic structure was investigated by X-ray absorption near-edge structure （XANES） analysis, proving the presence of unsaturated sulfur atoms and strong electronic coupling between MoS2 and SWNT. This study provides an in-situ synthetic route to create new multifunctional flexible hybridized catalysts and useful insights into the relationships electronic structure, and properties among the catalyst microstructure,

关键词： unsaturated-sulfur-rich MoS2 flexible X-ray absorption near-edgestructure hydrogen evolution

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

3D conformal radiotherapy combined with transcatheter arterial chemoembolization for hepatocellular carcinoma

引用

World Journal of Gastroenterology 2014年第45期20卷 17227-17234页

作者： Li-qun zou Bing-Lan Zhang Qing Chang Fu-Ping Zhu Yan-Yan Li Yu-Quan Wei Yong-Song Guan Department of Oncology Cancer Center State Key Laboratory of Biotherapy West China Hospital Sichuan University Department of Hepatobiliary Surgery The Ninth People’s Hospital of Chongqing

AIM: To compare transcatheter arterial chemoembolization (TACE) and 3D conformal radiotherapy (3D-CRT) with TACE monotherapy in hepatocellular carcinoma (HCC). METHODS: We searched all the eligible studies from the Cochrane Library, PubMed, Medline, Embase, and CNKI. The meta-analysis was performed to assess the survival benefit, tumor response, and the decline in alpha-fetoprotein (AFP) level. According to the heterogeneity of the studies, pooled OR with 95% CI were calculated using the fixed-effects or random-effects model. An observed OR > 1 indicated that the addition of 3D-CRT to TACE offered survival benefits to patients that could be considered statistically significant. Statistical analyses were performed using Review Manager Software. RESULTS: Ten studies met the criteria to perform a meta-analysis including 908 HCC participants, with 400 patients in the TACE/3D-CRT combination group and 508 in the TACE alone group. TACE combined with 3D-CRT significantly improved 1-, 2- and 3-year overall survival compared with TACE monotherapy (OR = 1.87, 95% CI: 1.37-2.55, P < 0.0001), (OR = 2.38, 95% CI: 1.78-3.17, P < 0.00001) and (OR = 2.97, 95% CI: 2.10-4.21, P < 0.00001). In addition, TACE plus 3DCRT was associated with a higher tumor response (complete remission and partial remission) (OR = 3.81; 95% CI: 2.70-5.37; P < 0.00001), and decline rates of AFP level (OR = 3.24, 95% CI: 2.09-5.02, P < 0.00001). CONCLUSION: This meta-analysis demonstrated that TACE combined with 3D-CRT was better than TACE monotherapy for patients with HCC, which needs to be confirmed by large multicenter trials. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.

关键词： Hepatocellular carcinoma Chemoembolization Three-dimensional conformal radiotherapy Meta-analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高效液相色谱法测定罗望子胶的单糖组成

引用

广州化工 2024年第1期52卷 119-121,142页

作者：王宝群赵晓琳林莎莎邹圣灿刘桂亭青岛琛蓝海洋生物工程有限公司山东青岛266100

采用柱前衍生化高效液相色谱法,对罗望子胶中主要单糖组分进行检测。选用Diamonsil-plus C 18-A^(*)色谱柱,用磷酸盐缓冲液-乙腈溶液流动相进行等度洗脱,流速设置1.0 mL/min,柱温35℃,进样量5μL,检测波长245 nm。罗望子胶中主要单糖组... 详细信息

采用柱前衍生化高效液相色谱法,对罗望子胶中主要单糖组分进行检测。选用Diamonsil-plus C 18-A^(*)色谱柱,用磷酸盐缓冲液-乙腈溶液流动相进行等度洗脱,流速设置1.0 mL/min,柱温35℃,进样量5μL,检测波长245 nm。罗望子胶中主要单糖组分葡萄糖、木糖和半乳糖的比例为52.05%、20.03%和12.17%。数据在各自浓度范围内线性关系良好(R≥0.9992),加样回收率在100.33%~101.34%之间,RSD小于2.0%,检测限在0.0005~0.0009 mg/L之间。综上,该检测方法适用于罗望子多糖胶中单糖组分测定。

关键词：高效液相色谱法柱前衍生罗望子多糖胶单糖组成

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

中国煤系气形成分布、甜点评价与展望

引用

天然气工业 2024年第10期44卷 1-21页

作者：刘翰林邹才能尹帅赵群陈艳鹏马锋邓泽东振林敏捷侯梅芳李士祥李勇郭秋雷蔺嘉昊路冠文关春晓孙粉锦中国石油勘探开发研究院北京市100083 西安石油大学地球科学与工程学院中国石油深圳新能源研究院有限公司中国矿业大学(北京)地球科学与测绘工程学院中国地质大学(武汉)资源学院中国石油长庆油田公司第三采气厂

为了给中国煤系气勘探开发提供借鉴和参考,基于非常规油气地质学理论及最新研究成果,构建了煤系气甜点区(段)评价方法。研究结果表明:①构建了包含4个要素共计15项指标的煤系气地质-工程甜点评价体系,其中的第一个要素是煤系富气甜点地... 详细信息

为了给中国煤系气勘探开发提供借鉴和参考,基于非常规油气地质学理论及最新研究成果,构建了煤系气甜点区(段)评价方法。研究结果表明:①构建了包含4个要素共计15项指标的煤系气地质-工程甜点评价体系,其中的第一个要素是煤系富气甜点地质参数,应重点评价煤系储层性质及地质力学层变形演化、规模及保存条件;②第二个要素是互层性煤系气渗流能力,要深刻揭示煤系气成藏模式、游离气与吸附气动态转换、天然裂缝发育特征、互层结构跨层渗流及复合断裂系统渗流异质性等;③第三个要素是含气量预测,应构建适合高频旋回互层结构煤系且与产能释放能力相匹配的含气量评价模型,准确评估煤系气资源量;④第四个要素是煤系合压储层改造,要重点评价岩石力学属性、地应力及脆性,结合动态监测技术优化合压效果,形成四维压裂技术方案;⑤煤系气甜点优选应综合考虑烃源性、储集性、含气性、保存性、成缝性、储改性和经济性。中国煤系气未来的发展趋势及建议:①深层煤层气(煤岩气)及铝土岩气将成为煤系气勘探开发的新对象、新方向;②深部煤系非常规天然气聚集成藏理论逐步形成;③强化多尺度孔缝表征、跨层渗流、合压增透、数智化新型天然气工厂排采模式等方面的研究;④联合多学科持续开展各类煤系气资源甜点综合评价,以助力煤系气勘探开发向深部进军。

关键词：煤系气煤岩气甜点评价要素地质参数渗流能力含气性评价合压储层改造

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Biotransformation ofα-asarone by Alternaria longipes CGMCC 3.2875

引用

Chinese Journal of Natural Medicines 2021年第9期19卷 700-705页

作者： zou Jian ZHANG Shuai ZHAO Huan WANG Yong-Heng ZHOU Zheng-qun CHEN Guo-Dong HU Dan LI Ning YAO Xin-Sheng GAO Hao Institute of Traditional Chinese Medicine&Natural Products College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents ofTCM and New Drugs ResearchJinan UniversityGuangzhou 510632China College of Traditional Chinese Materia Medica Shenyang Pharmaceutical UniversityShenyang 110016China College of Traditional Chinese Medicine Jinan UniversityGuangzhou 510632China Integrated Chinese and Western Medicine Postdoctoral Research Station Jinan UniversityGuangzhou 510632China

Biotransformation ofα-asarone by Alternaria longipes CGMCC 3.2875 yielded two pairs of new neolignans,(+)(7 S,8 S,7’S,8’R)iso-magnosalicin(1 a)/(-)(7 R,8 R,7’R,8’S)iso-magnosalicin(1 b)and(+)(7 R,8 R,7’S,8’R)magnosalicin(2 a)/(-)(7 S,8 S,7’R,8’S)magnosalicin(2 b),and four known metabolites,(±)acoraminol A(3),(±)acoraminol B(4),asaraldehyde(5),and 2,4,5-trimethoxybenzoic acid(6).Their structures,including absolute configurations,were determined by extensive analysis of NMR spectra,X-ray crystallography,and quantum chemical ECD *** cytotoxic activity and Aβ_(42)aggregation inhibitory activity of all the compounds were *** 2 displayed significant anti-Aβ_(42)aggregation activity with an inhibitory rate of 60.81%(the positive control EGCG:69.17%).In addition the biotransformation pathway ofα-asarone by Alternaria longipes CGMCC 3.2875 was proposed.

关键词： Biotransformation α-Asarone Alternaria longipes CGMCC 3.2875 Anti-Aβ_(42)aggregation activity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于纳米纤维素的柔性SERS基底在食品安全检测中的应用

引用

食品与药品 2024年第4期26卷 I0006-I0012页

作者：张忻娅胡沛杉宋利群张玮邹薇尚明王翠娟山东第一医科大学(山东省医学科学院) 山东省职业卫生与职业病防治研究院山东济南250062 山东第一医科大学(山东省医学科学院) 山东省肿瘤医院山东济南250114

现有食品安全检测方法大多存在样品预处理复杂、需使用大量有机萃取剂、检测过程耗时的问题。近年,研究者不断尝试构建简便、绿色、快速、经济低耗的检测方法,其中表面增强拉曼光谱技术(surface-enhanced Raman spectroscopy,SERS)以其... 详细信息

现有食品安全检测方法大多存在样品预处理复杂、需使用大量有机萃取剂、检测过程耗时的问题。近年,研究者不断尝试构建简便、绿色、快速、经济低耗的检测方法,其中表面增强拉曼光谱技术(surface-enhanced Raman spectroscopy,SERS)以其快速、灵敏等优点,在食品安全检测中极具应用潜力。构建高性能基底是SERS检测的前提,也是目前面临的主要挑战。纳米纤维素具有比表面积大、机械强度高、可改性和再生等优点,利用其制备的柔性SERS基底为解决食品中农药残留的快速富集和检测提供了新的可能。本文首先介绍了SERS技术及面临的问题,纳米纤维素材料的分类及优势,进而综述了基于柔性纳米纤维素的SERS基底应用于食品安全检测的现状,并讨论了其前景,旨在为新型SERS基底进一步应用于食品安全检测领域提供更多依据。

关键词：表面增强拉曼光谱纳米纤维素食品安全快速检测

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：