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Chinese Journal of Polymer Science 2014年第2期32卷 245-254页

作者： Yao Gao Gui-ying zong Hong-wei Bai 傅强 College of Polymer Science and Engineering State Key Laboratory of Polymer Materials Engineering Sichuan University Zhejiang Industry & Trade Vocational College

The combined effects of stretching and single-walled carbon nanotubes （SWCNTs） on crystalline structure and mechanical properties were systematically investigated in melt-spun polypropylene （PP） fibers prepared at two different draw ratios. The dispersion, alignment of the SWCNT bundles and interfacial crystalline structure in the composite fibers are significantly influenced by the stretching force during the melt spinning. The nanohybrid shish kebab （NHSK） superstructure where extended PP chains and aligned SWCNT bundle as hybrid shish and PP lamellae as kebab has been successfully obtained in the composite fibers prepared at the high draw ratio and the related formation mechanism is discussed based on the results of morphological observations and 2d-SAXS patterns. Large improvement in tensile strength and modulus has been realized at the high draw ratio due to the enhanced orientation and dispersion of SWCNT bundles as well as the formation of NHSK.

关键词： Stretching SWCNTs Nanohybrid shish kebab Mechanical properties.

Six-year analysis of key monitoring for bacterial strain distribution and antibiotic sensitivity in a hospital

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World Journal of Clinical Cases 2023年第30期11卷 7294-7301页

作者： zong-ying Li Dong Yang Chong-Hua Hao Clinical Laboratory Changzhi People’s HospitalChangzhi 046000Shanxi ProvinceChina Clinical Laboratory Shanxi Provincial People’s Hospital(The Fifth Clinical Medical College of Shanxi Medical University)Taiyuan 030001Shanxi ProvinceChina

BACKGROUND With the widespread use of antimicrobial drugs,bacterial resistance has become a significant problem,posing a serious threat to public *** prevalence of clinical infection strains in hospitals and their drug sensitivities are key to the appropriate use of antibiotics in clinical *** To identify prevalent bacteria and their antibiotic resistance profiles in a hospital setting,thereby guiding effective antibiotic usage by *** Specimens from across the institution were collected by the microbiology *** VITEK 2 compact fully automatic analyzer was used for bacterial identification and antibiotic sensitivity testing,and the WHONET5.6 software was utilized for statistical *** A total of 12062 bacterial strains of key monitoring significance were *** aureus demonstrated widespread resistance to penicillin,but none of the strains were resistant to vancomycin or ***,219 strains of methicillin-resistant coagulase-negative staphylococci and 110 strains of methicillin-resistant Staphylococcus aureus were *** faecalis showed moderate resistance to the third-generation quinolones ciprofloxacin and levofloxacin,but its resistance to nitrofurantoin and tetracycline was *** faecium displayed significantly lower resistance to third-and fourthgeneration quinolones than Enterococcus *** resistance of two key monitoring strains,Escherichia coli and Klebsiella pneumoniae,to piperacillin/tazobactam was 5%-8%.However,none of the Escherichia coli and Klebsiella pneumoniae strains were resistant to *** resistance of Acinetobacter baumannii to piperacillin/sulbactam was nearly 90%.Nonetheless,the resistance to tigecycline was low,and Pseudomonas aeruginosa demonstrated minimal resistance in the antibiotic sensitivity test,maintaining a resistance of<10%to the cephalosporin antibiotics cefotetan and cefoperazone over the last 6 *** resista

关键词： Antibiotic sensitivity test Monitoring bacterial antibiotic resistance Antimicrobial drugs Antimicrobial stewardship Combination therapies Antibiotic stewardship

Establishment and management of neurosurgery emergency observation ward during the COVID‑19 epidemic period

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Journal of Integrative Nursing 2020年第3期2卷 138-143页

作者： Hui‑Ting NIE zong‑ying ZOU Hui ZHANG Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

During the COVID‑19 epidemic period,the front‑line antiepidemic departments have attracted much ***,to meet people’s daily needs for the diagnosis and treatment,emergency department and intensive care unit are also the focus of work to control the source of infection,cut off the transmission route,and reduce the risk of novel coronavirus transmission while treating *** order to further strengthen the management,our department of neurosurgery took active measures in the emergency treatment for patients and summarized the coping strategies and relevant experience from the aspects of establishment of emergency observation wards,medical staff management,patients and family management,daily environment and object surface disinfection management,material management,and nursing quality management,hoping to provide reference for the nursing management of emergency wards after the outbreak of public health emergencies.

关键词： COVID‑19 neurosurgery emergency observation wards nursing management public health emergencies

Separation and analysis of aromatic hydrocarbons from two Chinese coals

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Journal of China University of Mining and Technology 2008年第3期18卷 432-436页

作者： DING Ming-jie LI Wen-dian XIE Rui-lun zong ying CAI Ke-ying PENG Yao-li zong Zhi-min WIE Rui-lun WEI Xian-yong School of Chemical Engineering China University of Mining ＆ Technology Xuzhou Jiangsu 221116 China Department of Light Industry Luohe Vocational Technology College Luohe Henan 462002 China Key Laboratory of Coal Conversion and New Carbon Materials Wuhan University of Science and Technology Wuhan Hubei 430081 China

Separation and analysis of aromatic hydrocarbons (AHs) from coals is of considerable significance for both fuel and non-fuel use of the coals. In present work two Chinese bituminous coals were selected for separation of AHs by ultrasonic extrac-tion with CS2 followed by column chromatography using hexane as eluent. A series of AHs were separated from the two coals and analyzed by GC/MS. FTIR was employed to characterize the raw coals and the extracted residues. The results of GC/MS analysis show that the separated AHs are mono- to tetracyclic arenes, among which the principle AHs are alkyl naphthalenes and phenan-threnes. Obvious differences in the composition and the structure of AHs exist between the two coals, i.e., the AHs from Tongting coal tend to be higher rings compared to those from Pingshuo coal both from the variety and from the abundance of the AHs. FTIR analysis shows that the raw and extracted coals are similar in terms of functional groups, suggesting that the composition and structure of CS2 extract, especially the AHs, from coals can be used to interpret the coal structure to some extent.

关键词： aromatic hydrocarbon column chromatography coal GC-MS

Paeoniflorin alleviates depression by inhibiting the activation of NLRP3 inflammasome via promoting mitochondrial autophagy

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Chinese Journal of Natural Medicines 2024年第6期22卷 515-529页

作者： SU Lili GUO Pengli GUO Xiangjuan HE Zhongmei ZHAO Yan zong ying LI Jianming CHEN Weijia DU Rui College of Chinese Medicinal Materials Jilin Agricultural UniversityChangchun 130118China Jilin Provincial Engineering Research Center for Efficient Breeding and Product Development of Sika Deer Changchun 130118China Key Laboratory of Animal Production and Product Quality and Security Ministry of EducationMinistry of National EducationChangchun 130118China

Depression ranks among the most common neuropsychiatric disorders *** studies examining the roles of inflammation and mitochondrial autophagy in the antidepressant efficacy of paeoniflorin(PF)are *** study aimed to elucidate PF’s antidepressant mechanism by promoting autophagy and inhibiting NLRP3 inflammasome activation using chronic unpredictable mild stimulation(CUMS)-induced C57BL/6 mouse models in vivo and corticosterone(CORT)-induced HT22 cell models in *** demonstrated that PF enhanced the viability of HT22 cells following CORT exposure,restored mitochondrial membrane poten-tial(MMP),reduced reactive oxygen species accumulation,increased LC3 fluorescence intensity,and suppressed inflammatory cy-tokine secretion and inflammation ***,PF ameliorated depressive behaviors induced by CUMS and improved damage in hippocampal *** also reduced the expression of NLRP3,ASC,Caspase-1,IL-1β,and the assembly of the NLRP3 ***,PF upregulated the expression of autophagy-related proteins in the hippocampus,facilitating the clearance of damaged mitochondria and enhancing *** role of autophagy in PF’s antidepressant effects was further confirmed through the use of the autophagy inhibitor 3-methyladenine(3-MA),which reduced the efficacy of *** conclusion,PF effectively improved depressive behaviors in CUMS-induced mice and reduced NLRP3-mediated inflammation both in vivo and in vitro,likely via the in-duction of autophagy.

关键词： Paeoniflorin Depression Autophagy NLRP3 inflammasome

Diversity, Structure, and Marker-Trait Association Analysis of the Maize Recombinant Inbred Line Population

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Agricultural Sciences in China 2011年第7期10卷 975-986页

作者： CHEN Jing-tang HU Li-zong ZHU Li-ying GUO Jin-jie ZHAO Yong-feng HUANG Ya-qun College of Agronomy Agricultural University of Hebei/Hebei Sub-Center of Chinese National Maize Improvement Center/Northern China Key Laboratory for Crop Germplasm Resources Ministry of Education Baoding 007100 P.R.China

Association mapping has emerged as a new tool to elucidate complex quantitative trait loci in maize, but there are few reports about systematic association analysis for the specific SSR markers with agronomic traits of interest in China. We investigated the morphological and genetic diversity and population structure for 76 maize recombinant inbred lines, and then association analysis were further performed between 48 simple sequence repeat loci and 17 morphological traits, consisting of nine ear-related traits and eight other traits. The 48 SSR markers were screened out and further classified into two groups including a group of loci in regions harboring reported quantitative trait loci that affect ear shape and a group of markers distributing on the whole genome randomly. The result indicated that the population of recombinant inbred lines was structured, showing five subpopulations. Our association results revealed that there were 82, 59, and 40 significant associations detected by K-test, logistic regression, and both analysis, respectively. When the 17 traits were considered separately, the significant associations between Q-SSRs and E-traits were raised to 27.8%, whereas the other groups of combinations ranged between 2.3 and 6.3%. As the proportion of significant associations is higher among the Q-SSR subset of markers and the subset of traits related to ear shape than those for all of the other combinations, we conclude that this approach is valid for establishing true positive marker-trait relationships. Our results also demonstrated that association mapping could complement and enhance previous QTL information for marker-assisted selection.

关键词： maize ear shape association mapping recombinant inbred lines

Group separation and analysis of a carbon disulfide-soluble fraction from Shenfu coal by column chromatography

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Journal of China University of Mining and Technology 2008年第1期18卷 27-32页

作者： DING Ming-jie zong Zhi-min zong ying OUYANG Xiao-dong HUANG Yao-guo ZHOU Lei ZHENG Yu-xuan ZHOU Xiao WEI Yan-bin WEI Xian-yong School of Chemical Engineering and Technology China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China Department of Light Industry Luohe Vocational Technology College Luohe Henan 462002 China Key Laboratory of Coal Conversion and New Carbon Materials Wuhan University of Science and Technology Wuhan Hubei 430081 China

A carbon disulfide-soluble fraction (CDSSF) from Shenfu coal was separated into five fractions by silica-gel column chromatography using hexane and n-hexane/ethyl acetate binary eluent. The five fractions include four clear group fractions and a nonpolar fraction. All the fractions were analyzed by GC/MS. A total of 204 compounds were detected from the original CDSSF and its further separated fractions, with 173 compounds more than those detected by studying the original CDSSF directly. The results demonstrate a clear group separation by column chromatography in coal organic components and a more accessibility to coal components compared with the solvent extraction only.

关键词： group separation column chromatography coal

Effects of continuous tracheal gas insufflation during pressure limited ventilation on pulmonary surfactant in rabbits with acute lung injury

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Chinese Medical Journal 2006年第17期119卷 1415-1420页

作者： ZHU Guang-fa ZHANG Wei zong Hua LIANG ying Department of Respiratory Medicine Beijing Anzhen HospitalCapital University of Medical Science Beijing 100029 China

Background Pulmonary surfactant dysfunction may contribute to the development of ventilator induced lung injury （VILI）. Tracheal gas insuffiation （TGI） is a technique in which fresh gas is introduced into the trachea and augment ventilation by reducing the dead space of ventilatory system, reducing ventilatory pressures and tidal volume （VT） while maintaining constant partial arterial CO2 pressure （PaCO2）. We hypothesised that TGI limited peak inspiratory pressure （PIP） and VT and would minimize conventional mechanical ventilation （CMV） induced pulmonary surfactant dysfunction and thereby attenuate VILI in rabbits with acute lung injury （ALI）. Methods ALI was induced by intratracheal administration of lipopolysaccharide in anaesthetized, ventilated healthy adult rabbits randomly assigned to continuous TGI at 0.5 L/min （TGI group） or CMV group （n=8 for each group）, and subsequently ventilated with limited PIP and VT to maintain PaCO2 within 35 to 45 mmHg for 4 hours. Physiological dead space to VT ratio （VD/VT）, dynamic respiratory compliance （Cdyn） and partial arterial O2 pressure （PaO2） were monitored. After ventilation, lungs were analysed for total phospholipids （TPL）, total proteins （TP）, pulmonary surfactant small to large aggregates ratio （SA/LA） in bronchoalveolar lavage fluid （BALF） and for determination of alveolar volume density （Vv）, myeloperoxidase and interleukin （IL）-8. Results TGI resulted in significant （P〈0.05 or P〈0.01） decrease in PIP [（22.4±1.8） cmH20 vs （29.5±1.1） cmH2O], VT [（6.9±1.3） ml/kg vs （9.8±1.11） ml/kg], VD/VT [（32±5）% vs （46±2）%], TP [（109±22） mg/kg vs （187±25） mg/kg], SA/LA （2.5±0.4 vs 5.4±0.7）, myeloperoxidase [（6.2±0.5） U/g tissue vs （12.3±0.8） U/g tissue] and IL-8 [（987±106） ng/g tissue vs （24±3） mN/m] of BALF, and significant （P〈0.05） increase in Cdyn [（0.47±0.02） ml·cmH2O^-1·kg^-1 vs （0.31±0.02） ml·cmH2O^-1·kg^-1], PaO2 [（175±24） mmHg vs （135±26） mmHg], TPL/TP （52±8 vs 33±11） and Vv （0.65±0.05 vs 0.44±0.07） as compared with CMV

关键词： tracheal gas insufflation acute lung injury pulmonary surfactant ventilator induced lung injury mechanical ventilation

Calixarenes enabling well-adjusted organic-inorganic interface for inverted organic solar cells with 18.25%efficiency and multifold improved photostability under max power point tracking

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Science China Chemistry 2023年第1期66卷 195-201页

作者： Shitong Li Zheng Xiao Juan-Juan Li zong-ying Hu Yang Yang Bin Kan Dong-Sheng Guo Xiangjian Wan Zhaoyang Yao Chenxi Li Yongsheng Chen State Key Laboratory of Elemento-Organic Chemistry The Centre of Nanoscale Science and Technology and Key Laboratory of Functional Polymer MaterialsRenewable Energy Conversion and Storage Center(RECAST)College of ChemistryNankai University Tianjin300071China College of Materials Science and Engineering Nankai UniversityTianjin 300350China The Institute of Seawater Desalination and Multipurpose Utilization Ministry of Natural Resources(Tianjin)Tianjin 300192China

Compared with organic solar cells(OSCs) adopting conventional architecture,inverted OSCs have offered generally better stability,where Zn O is the most widely used electron transporting layer(ETL) *** ZnO-based inverted OSCs,a welltuned interface of organic(active layer)-inorganic(Zn O film) with matched surface energy(γS) is critical for both high performance and high *** this work,two typical calixarenes,C4A and Bu C4A,were employed as the tuning agents to adjust this organic-inorganic interface for ZnO-based inverted *** a result,with PM6:L8-BO as the active layer,significantly promoted power conversion efficiencies(PCEs) from 17.14%(for ZnO) to 18.25%(for ZnO/C4A) and 17.80%(for ZnO/Bu C4A) were *** studies indicate that the enhanced performance is due to the faster charge extraction process,the suppressed recombination and more ideal internal electric field in ZnO/calixarene-based *** addition,wellmatched interface energy and more ordered molecular aggregation in active layer effectively improved photostability and thermal stability for ZnO/calixarene-based *** results indicate that calixarenes could act as effective modifying agents of ZnO to improve inverted OSCs’ performance and stability simultaneously,and likely also stimulate calixarenes’ and other macromolecules’ broader studies in other organic electronic devices.

关键词： organic solar cell calixarenes interface adjustment ZnO modification high performance high stability

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基于逆拉伸变换的脑血管减影图像非刚性配准

光电子．激光 2008年第8期19卷 1137-1142页

作者：刘斌欧宗瑛大连理工大学精密与特种加工教育部重点实验室辽宁大连116024

提出了一种基于逆拉伸空间变换的蒙片像素点灰度值映射求解方法。实验中使蒙片网格化以产生恰当的控制点,采用最大减影直方图能量相似性测度准则和鲍威尔优化搜索方法,对蒙片图像和活片图像进行局部变形非刚性配准。该算法有效保证了蒙... 详细信息

提出了一种基于逆拉伸空间变换的蒙片像素点灰度值映射求解方法。实验中使蒙片网格化以产生恰当的控制点,采用最大减影直方图能量相似性测度准则和鲍威尔优化搜索方法,对蒙片图像和活片图像进行局部变形非刚性配准。该算法有效保证了蒙片图像变形前后灰度值变化的拓扑一致,使变形后的蒙片图像仍保持清晰准确的轮廓,配准后的减影图像质量良好,噪声和伪影明显减少,同时省去插值计算过程,配准速度明显提高,为临床中的脑血管病变诊断提供了有力支持。

关键词：数字减影血管造影非刚性配准拉伸变换像素映射