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Influence maximization with limit cost in social network

Science China(Information Sciences) 2013年第7期56卷 168-181页

作者： WANG Yue HUANG WeiJing zong lang WANG TengJiao YANG DongQing Department of Computer Science School of Information Central University of Finance and Economics Key Laboratory of High Confidence Software Technologies (Peking University) Ministry of Education

Social networking service (SNS) applications are changing the way information spreads in online communities. As real social relationships are projected into SNS applications, word of mouth has been an important factor in the information spreading processes of those applications. By assuming each user needs a cost to accept some specific information, this paper studies the initial "seed user" selection strategy to maximize information spreading in a social network with a cost budget. The main contributions of this paper are: 1) proposing a graphic SEIR model (gSEIR) by extending the epidemic compartmental model to simulate the dynamic information spreading process between individuals in the social network; 2) proposing a formal definition for the influence maximization problem with limit cost (IMLC) in social networks, and proving that this problem can be transformed to the weighted set-cover problem (WSCP) and thus is NP-Complete; 3) providing four different greedy algorithms to solve the IMLC problem; 4) proposing a heuristic algorithm based on the method of Lagrange multipliers (HILR) for the same problem; 5) providing two parts of experiments to test the proposed models and algorithms in this paper. In the first part, we verify that gSEIR can generate similar macro-behavior as an SIR model for the information spreading process in an online community by combining the micro-behaviors of all the users in that community, and that gSEIR can also simulate the dynamic change process of the statuses of all the individuals in the corresponding social networks during the information spreading process. In the second part, by applying the simulation result from gSEIR as the prediction of information spreading in the given social network, we test the effectiveness and efficiency of all provided algorithms to solve the influence maximization problem with cost limit. The result show that the heuristic algorithm HILR is the best for the IMLC problem.

关键词： data mining social network influence maximization graph-based diffusion model information propagation

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INFERIOR-SEPTAL MYOCARDIAL INFARCTION MISDIAGNOSED AS ANTERIOR-SEPTAL MYOCARDIAL INFARCTION:ELECTROCARDIOGRAPHIC,SCINTIGRAPHIC,AND ANGIOGRAPHIC CORRELATIONS

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Chinese Medical Sciences Journal 2007年第4期22卷 228-231页

作者： Ji-lin Chen Zuo-xiang He Zai-jia Chen Jin-qing Yuan Yue-qin Tian Shu-bin Qiao Rong-fang Shi Yi-da Tang zong-lang Lu Center for Diagnosis ＆ Treatment of Coronary Heart Disease Cardiovascular Institute ＆ Fuwai Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100037

Objective To explore the infarct sites in patients with inferior wall acute myocardial infarction （AMI） concomitant with ST segment elevation in leads V1-V3 and leads V3R-V5R. Methods Five patients diagnosed as inferior, right ventricular, and anteroseptal walls AMI at admission were enrolled. Electrocardiographic data and results of isotope ^99mTc-methoxyisobutylisonitrile （MIBi） myocardial perfusion imaging and coronary angiography （CAG） were analyzed. Results Electrocardiogram showed that ST segment significantly elevated in standard leads Ⅱ, Ⅲ, aVF, and leads V1-V3, V3R-V5R in all five patients. The magnitude of ST segment elevation was maximal in lead V1 and decreased gradually from lead V1 to V3 and from lead V1 to V3R-V5R. There was isotope ^99mTc-MIBI myocardial perfusion imaging defect in inferior and basal inferior-septal walls. CAG showed that right coronary artery was infarct-related artery. Conclusions The diagnostic criteria for basal inferior-septal wall AMI can be formulated as follows：（ 1 ） ST segment elevates ≥2 mm in lead V1 in the clinical setting of inferior wall AMI; （2） the magnitude of ST segment elevation is the tallest in lead V1 and decreases gradually from lead V1 to V3 and from lead V1 to V3R-V5R. With two conditions above, the basal inferior-septal wall AMI should be diagnosed.

关键词： acute myocardial infarction basal inferior-septal wall electrocardiogram

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Clinical observation of cancer-related fatigue treated with ginger-isolated moxibustion in the patients with gastric cancer

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World Journal of Acupuncture-Moxibustion 2021年第1期31卷 1-5页

作者： Na SONG Yue-yunlu ZHAO Hong-jian XU Jing WANG zong-lang LAI Xin YU Yue WU Department of Oncology Chongqing Municipal Chinese Medicine HospitalChongqing 400021China Chongqing Jiangbei District Daqing Community Health Service Center Chongqing 400021China Department of Gastroenterology Chongqing Municipal Chinese Medicine HospitalChongqing 400021China

Objective:To observe the clinical therapeutic effect of ginger-isolated moxibustion on cancer-related fa tigue(CRF)in the patients with gastric ***:The patients in the conventional treatment group accepted conventional *** the ginger-isolated moxibustion group,on the base of the conventional chemotherapy,ginger-isolated moxibustion was added at Shénquè(神阙CV8),Shàngwǎn(上脘CV13),Zhóngwǎn(中脘CV12),Qìhǎi(气海CV6]and Guānyuán(关元CV4).Chemotherapy for 3 weeks was as 1 cycle and 2 cycles of chemotherapy were ***:After treatment,plasma cortisol(Cor)was increased and adreno-cortico-tropic-hormone(ACTH)decreased in the ginger-isolated moxibustion group,indicating the statistical differences as compared with the levels before treatment(P<0.05),and the differences in plasma Cor and ACTH were significant statistically between the two groups(P<0.05).After treatment,the score of each item of the revised fatigue scale was reduced in the ginger-isolated moxibustion group,indicating the statistical differences as compared with the score before treatment(P<0.05).The score of the revised fatigue scale was different statistically between the two groups(P<0.05).After treatment,the score of each of the items,***,nausea&vomiting,pain,dyspnea,insomnia,anorexia,constipation,diarrhea and financial difficulty,was reduced in the ginger-isolated moxibustion group,indicating the statistical differences as compared with the score before treatment successfully(P<0.05).The differences were significant statistically in fatigue,nausea&vomiting,pain,dyspnea,insomnia,anorexia,constipation,diarrhea and economic difficulty between the two groups(P<0.05).Conclusion:Ginger-isolated moxibustion achieves a satisfactory effect on CRF in the patients with gastric cancer and deserves to be promoted in clinical practice.

关键词： Ginger-isolated moxibustion Gastric cancer Cancer-related fatigue Randomized controlled trial(RCT)

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A New Efficient Mobile Micropayment Scheme

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Wuhan University Journal of Natural Sciences 2004年第6期9卷 935-938页

作者： FU Xiong 1,2 , YANG zong-kai 1 ,lang Wei-min 1 ,TAN Yun-meng 1 1.Department of Electronics and Information Engineering, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China 2.PLA Guangdong PMC, Guangzhou 510501, Guangdong, China Department of Electronics and Information Engineering Huazhong University of Science and Technology Wuhan 430074 Hubei China

This paper proposes a micropayment scheme designed for GSM mobile scenario, where the overload of computation, storage and communication for mobile phone is reduced by directing operations normally performed by the mobile user to the static portion of the network in view of its limited capability. Messages which received and sent during the payment are very simple and public key infrastructure is not needed, which reduces delay and removes the possibility of incomplete payment due to communications failures. Furthermore, all the information related to payment is encrypted by a shared symmetric key in our scheme, so the privacy of the mobile user is protected and the security of information is guaranteed. Compared with other mobile micropayment schemes in existence, no public-key operation is required, which minimizes the computation and storage overhead dramatically. In addition, restricted anonymous is also provided in our scheme. Key words micropayment - mobile phone - GSM - fairness CLC number TP 309.2 Foundation item: Supported by the National Natural Science Foundation of China (90104033)Biography: FU Xiong (1968-), male, Ph.D. candidate, research direction information security, electronic payment and modern cryptography.

关键词： micropayment mobile phone GSM fairness

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“以赛促教”推动专业教学水平提升——以中药传统技能大赛性状鉴别赛项教学为例

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教育教学论坛 2024年第51期 157-160页

作者：廖宗浪广东科贸职业学院食品生物学院

在现代职业教育体系中，技能竞赛已成为推动教学改革、提升教学质量的重要途径之一。通过探讨“以赛促教”的教学模式在“中药鉴定技术”课程中的应用与成效。通过引入中药传统技能大赛内容，更新教学内容与方法，利用实景投屏、3D虚拟... 详细信息

在现代职业教育体系中，技能竞赛已成为推动教学改革、提升教学质量的重要途径之一。通过探讨“以赛促教”的教学模式在“中药鉴定技术”课程中的应用与成效。通过引入中药传统技能大赛内容，更新教学内容与方法，利用实景投屏、3D虚拟仿真等信息化手段，增强教学的直观性和互动性，从而有效提升学生的学习兴趣和综合能力。研究表明，该教学模式不仅促进了学生职业能力的显著提升，还推动了教师教学水平的提升和教学方法的创新，为“中药鉴定技术”课程的教学改革提供了新思路，对培养高素质中药鉴定人才具有重要意义。

关键词：以赛促教中药传统技能性状鉴别教学改革职业教育

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Ultrasonic Chinese herbal medication penetration therapy at Tiānshū(天枢 ST25) for opioid-induced constipation with liver stagnation and spleen deficiency

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World Journal of Acupuncture-Moxibustion 2020年第1期30卷 13-18页

作者： Na SONG Ling-zhan MENG Jun CHENG Ying LI Xin ZHOU Jing WANG Hong-jian XU Xuan GAO zong-lang LAI Department of Oncology Chongqing Chinese Medicine HospitalChongqing 400021China Department of Nephrology Chongqing Hospital of Traditional Chinese MedicineChongqing 400021China Department of Endocrinology Chongqing Hospital of Traditional Chinese MedicineChongqing 400021China

Objectives:To observe the clinical effect on opioid-induced constipation of liver stagnation and spleen deficiency treated with the ultrasonic penetration of the No.1 constipation herbal formula at Tiānshū(天枢ST25).Methods:A total of 126 patients that were in compliance with the inclusion criteria were randomized into an acupoint group(41 cases),a Chinese medication group(42 cases)and a western medication group(43 cases).In the acupoint group,the ultrasonic penetration of the No.1 constipation herbal formula at bilateral Tiānshū(天枢ST25)were *** the Chinese herbal medication group,the No.1 constipation herbal formula was prescribed for oral *** the western medication group,polyethylene glycol electrolyte powder was prescribed for oral *** treatment was given once a day,for 14 days *** and after treatment,the constipation symptom score,the score of the patient assessment of constipation quality of life(PAC-QOL),the situation of nitric oxide synthetase(NOS)in serum were observed in each *** safety indicators in the observation included diarrhea,allergic reaction,liver dysfunction,skin lesions,***:A total of 122 cases accomplished the *** total effective rate was 82.5%in the acupoint group,80.48%in the Chinese medication group and 78.04%in the western medication *** constipation symptoms were all relieved in the three groups,indicating the statistical significance as compared with those before treatment(P<0.01,P<0.05).In the acupoint group and the western medication group,the improvements in the three symptom items,*** or scurrying pain in the chest,hypochondriac region or the bilateral sides of the abdomen,depression or irritability and poor appetite,were better than the western medication group(P<0.01,P<0.05).The improvements in all of the symptoms in the acupoint group were better than the Chinese medication group(all P<0.05).The PACQOL score was improved in each group after treatment an

关键词： Opioid-induced constipation No.1 constipation formula Ultrasonic medication penetration Tiānshū(天枢ST25)

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黄芪注射液对大鼠放射性肺损伤和转化生长因子β_1/Smads信号通路的影响

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中国临床药理学杂志 2019年第5期35卷 442-444页

作者：赵蓉赖宗浪江飞龙曹晓静李晓清重庆市中医医院超声科重庆400012 重庆市中医医院肿瘤科重庆400012 重庆市中医医院病理科重庆400012

目的研究黄芪对大鼠放射性肺损伤(RILI)的保护作用及其机制。方法按照体重将SD雄性大鼠随机分成3组:空白对照组、模型组和实验组,每组12只。模型组和实验组大鼠的右肺部2 cm×3. 3 cm部位用直线加速器辐射,每周10 Gy,连续2周;空白对照... 详细信息

目的研究黄芪对大鼠放射性肺损伤(RILI)的保护作用及其机制。方法按照体重将SD雄性大鼠随机分成3组:空白对照组、模型组和实验组,每组12只。模型组和实验组大鼠的右肺部2 cm×3. 3 cm部位用直线加速器辐射,每周10 Gy,连续2周;空白对照组进行假辐射处理。辐照结束后第2天,实验组大鼠予以黄芪注射液0. 5 m L·kg^(-1)腹腔灌注,1次/天,连续9周,空白对照组与模型组予以相同体积0. 9%NaCl腹腔灌注。观察大鼠生存率,用免疫印迹法测定转化生长因子β1(TGF-β1)/Smads信号通路蛋白水平。结果空白对照组、模型组与实验组的大鼠肺指数分别为3. 77±0. 41,4. 86±1. 21和3. 90±0. 17;这3组的磷酸化Smad2/3蛋白表达的灰度值分别为0. 77±0. 13,1. 48±0. 26和0. 78±0. 09;这3组的TGF-β_1蛋白表达灰度值分别为1. 29±0. 18,1. 20±0. 27和0. 54±0. 13。上述指标,模型组与空白对照组比较或者实验组与模型组比较,差异均有统计学意义(均P <0. 05)。结论黄芪注射液可能主要通过抑制P-Smad2/3和TGF-β_1的蛋白量从而抑制肺纤维化的发展,并降低RILI的严重程度。

关键词：黄芪注射液放射性肺损伤转化生长因子β1 Smads信号通路

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小剂量阿司匹林致不良反应的文献分析及护理

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全科护理 2014年第24期12卷 2209-2212页

作者：田敏郎宗娥李雪梅中国人民解放军第三军医大学第二附属医院重庆市涪陵中心医院

[目的]了解小剂量阿司匹林(75mg/d^150mg/d)致不良反应发生的特点、趋势及相关因素。[方法]检索《中国期刊全文数据库》2000年—2013年收载的有关小剂量阿司匹林致不良反应文献,筛选出符合卫生部不良反应诊断标准的文献27篇,共125例不... 详细信息

[目的]了解小剂量阿司匹林(75mg/d^150mg/d)致不良反应发生的特点、趋势及相关因素。[方法]检索《中国期刊全文数据库》2000年—2013年收载的有关小剂量阿司匹林致不良反应文献,筛选出符合卫生部不良反应诊断标准的文献27篇,共125例不良反应病例,并进行分类、统计、分析。[结果]小剂量阿司匹林不良反应以消化系统、血液系统的损害例数较多,占总例数的80.0%和5.6%。消化系统损害以上消化道出血为主,血液系统损害以血小板减少为主要表现。[结论]临床上小剂量使用阿司匹林过程中可能出现药物不良反应,应加强病人用药教育,密切关注不良反应,及时调整给药方法,以确保用药安全。

关键词：阿司匹林药物不良反应合理用药

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急性髓系白血病患者骨髓细胞相关分子标志物表达研究

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中国实验血液学杂志 2014年第5期22卷 1193-1198页

作者：黄晓王荣华李冬云赖宗浪褚雨霆张宇陈信义北京中医药大学东直门医院肿瘤血液科北京100700 美国耶鲁大学医学院流行病与公共卫生系美国康涅狄格州纽黑文06520 北京市、教育部重点实验室(中医内科学) 北京100700

本研究旨在探讨急性髓系白血病患者骨髓细胞相关分子标志物(PTEN、mTOR、NF-kB、CD44、PI3K)表达。选取20例住院患者,抽取骨髓液,先涂片检查骨髓白血病细胞百分比,并分临床缓解(9例)与未缓解(11例)两组。再将剩余的骨髓液以石蜡包埋,常... 详细信息

本研究旨在探讨急性髓系白血病患者骨髓细胞相关分子标志物(PTEN、mTOR、NF-kB、CD44、PI3K)表达。选取20例住院患者,抽取骨髓液,先涂片检查骨髓白血病细胞百分比,并分临床缓解(9例)与未缓解(11例)两组。再将剩余的骨髓液以石蜡包埋,常规切片,免疫组化技术检测PTEN、mTOR、NF-kB、CD44、PI3K表达。结果表明:光学显微镜观察缓解组与未缓解组PTEN、mTOR、NF-kB、CD44、PI3K阳性细胞表达率分别为33.3、33.3、77.8、22.2、0与63.6,18.2,90.9,63.6,0。经统计学处理,PTEN和CD44两组比较,有统计学意义(P<0.05),荧光表达强度与图像分析也得出同样的研究结果。结论表明:急性白血病骨髓细胞PTEN、CD44高表达可作为急性髓系白血病难治诊断和预后判定的重要参考指标。

关键词：急性髓系白血病骨髓细胞分子标志物 PTEN CD44

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不同测量方法和判断标准对血压值的影响研究

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护理研究（上旬版） 2007年第3期21卷 615-616页

作者：刘继终杨国利郎宗娥重庆市涪陵中心医院

[目的]探讨用汞柱式血压计进行不同的血压测量方法、判断标准时血压值的变化。[方法]选择内科病人126例,采用汞柱式血压计通过不同的血压测量和判断方法进行自身对照,比较左右上肢、听诊器胸件置于不同状态时,首次看到水银柱波动值与听... 详细信息

[目的]探讨用汞柱式血压计进行不同的血压测量方法、判断标准时血压值的变化。[方法]选择内科病人126例,采用汞柱式血压计通过不同的血压测量和判断方法进行自身对照,比较左右上肢、听诊器胸件置于不同状态时,首次看到水银柱波动值与听到第一声搏动音、变音值与声音消失值血压变化。[结果]左上肢和右上肢的收缩压和舒张压差别有统计学意义;听诊器胸件置于不同状态的收缩压和舒张压也有差异;首次看到水银柱波动和听到第一声搏动音的读数也存在差异;舒张压以第1次变音和声音消失的判断结果也存在差异。[结论]血压测量部位一般选择右上肢,舒张压一般应以消失音(Korotkoff第5期)为准,袖带位置不准确使测得的血压偏低,水银波动值与主动脉压和收缩压的关系有待进一步研究。

关键词：汞柱式血压计测量方法血压判断标准

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