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Oncology Research 2024年第9期32卷 1453-1465页

作者： ziyong liu TAO MA JINFANG LI WEI REN ZHIXIN ZHANG Department of Cardiothoracic Surgery 970th Hospital of the People’s Liberation ArmyWeihai264209China Department of Cardiac Ultrasound Weihai Municipal HospitalWeihai264200China

Background:Interleukin 13 receptor subunit alpha 2(IL13RA2)plays an essential role in the progression of many ***,the role of IL13RA2 in infantile haemangioma(IH)is still *** and Methods:IL13RA2 expression in IH tissues was analyzed using western blot,qRT-PCR,and *** role of IL13RA2 in haemangioma-derived endothelial cells(HemECs)was determined following knockdown or overexpression of IL13RA2 using CCK-8,colony formation,apoptosis,wound healing,tubule formation,Transwell,and western ***:IL13RA2 expression was upregulated in IH ***13RA2 overexpression promoted proliferation,migration,and invasion of HemECs and induced glycolysis,which was confirmed with a glycolysis ***,IL13RA2 interacted withβ-catenin and activated the Wnt/β-catenin pathway in HemECs,which were involved in the above-mentioned effects of ***:These findings revealed that targeting IL13RA2 is a potential therapeutic approach for IH.

关键词： Infantile haemangioma IL13RA2 Glycolysis Wnt/β-catenin pathway

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文水县肉牛产业及机械化发展研究

中国农机装备 2024年第1期 94-96页

作者：刘子勇山西省农业规划设计研究院有限公司太原030002

文水县作为具有丰富畜牧资源的县份,拥有发展肉牛产业得天独厚的条件。探讨文水县肉牛产业的发展现状,分析面临的挑战,并提出促进该产业高质量发展的对策,提升肉牛产业的整体竞争力,促进农民增收和地方经济的可持续发展,具有重要的现实... 详细信息

文水县作为具有丰富畜牧资源的县份,拥有发展肉牛产业得天独厚的条件。探讨文水县肉牛产业的发展现状,分析面临的挑战,并提出促进该产业高质量发展的对策,提升肉牛产业的整体竞争力,促进农民增收和地方经济的可持续发展,具有重要的现实意义。

关键词：文水县肉牛产业发展问题对策

Measurement Method of Compressibility and Thermal Expansion Coefficients for Density Standard Liquid at 2329 kg/m^3 based on Hydrostatic Suspension Principle

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Chinese Journal of Mechanical Engineering 2014年第4期27卷 779-784页

作者： WANG Jintao liu ziyong XU Changhong LI Zhanhong Division of Mechanics and Acoustics National Institute of Metrology

The accurate measurement on the compressibility and thermal expansion coefficients of density standard liquid at 2329kg/m3（DSL-2329） plays an important role in the quality control for silicon single crystal manufacturing. A new method is developed based on hydrostatic suspension principle in order to determine the two coefficients with high measurement accuracy. Two silicon single crystal samples with known density are immersed into a sealed vessel full of DSL-2329. The density of liquid is adjusted with varying liquid temperature and static pressure, so that the hydrostatic suspension of two silicon single crystal samples is achieved. The compression and thermal expansion coefficients are then calculated by using the data of temperature and static pressure at the suspension state. One silicon single crystal sample can be suspended at different state, as long as the liquid temperature and static pressure function linearly according to a certain mathematical relationship. A hydrostatic suspension experimental system is devised with the maximal temperature control error ±50 μK; Silicon single crystal samples can be suspended by adapting the pressure following the PID method. By using the method based on hydrostatic suspension principle, the two key coefficients can be measured at the same time, and measurement precision can be improved due to avoiding the influence of liquid surface tension. This method was further validated experimentally, where the mixture of 1, 2, 3-tribromopropane and 1,2-dibromoethane is used as DSL-2329. The compressibility and thermal expansion coefficients were measured, as 8.5′10–4 K–1 and 5.4′10–10 Pa–1, respectively.

关键词： silicon single crystal sample hydrostatic suspension density standard liquid at 2329 kg/m~3 compressibility coefficient thermal expansion coefficient measurement

Perforated nitrogen-rich graphene-like carbon nanolayers supported Cu-In catalyst for boosting CO_(2) electroreduction to CO

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Journal of Energy Chemistry 2022年第12期75卷 383-390,I0010页

作者： Xinxin Zhang Yuxiao Zhu ziyong liu Fuli Li Wei Zhou Zichao Dong Jingxin Fan Licheng liu Chunhua Du Laboratory of Reaction and Separation Technology Qingdao Agricultural UniversityQingdao 266109ShandongChina CAS Key Laboratory of Bio-based Materials Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101ShandongChina CenterTech Tianjin Chemical Research and Design Institute Co. Ltd.Tianjin 300131China

The combination of a powerful CO_(2)-enriching carrier and robust active component provides a new idea for the construction of efficient catalysts for electrocatalytic CO_(2)***,novel perforated nitrogen-rich graphene-like carbon nanolayers(PNGC)are prepared from biomass derivatives,which promotes the oriented deposition of In-doped Cu_(2)(OH)_(3)(NO_(3))nanosheet patches.A robust Cu-In/PNGC composite catalyst is then obtained via simple in-situ electrochemical ***,CuIn/PNGC exhibits a CO Faradaic efficiency(FECO)of 91.3%and a remarkable CO partial current density(jCO)of 136.4 m A cm^(-2)at a moderate overpotential of 0.59 V for electrocatalytic CO_(2)reduction reaction(CO_(2)RR).DFT calculations and experimental studies indicate that the strong carrier effect of PNGC makes PNGC carried Cu-In nanosheets improved the adsorption capacity of CO_(2)gas,reconfigured electronic structure,and reduced free energy of key intermediate formation,thereby the CO_(2)activation and conversion are promoted.

关键词： CO_(2)electroreduction CO Cu-In/PNGC Patch Perforated nitrogen-rich graphene-like carbon nanolayers

Discussion on bearing capacity of soft rock ground based on in-situ load test

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Engineering Sciences 2010年第4期8卷 37-41页

作者： Gao Wenhua Zhu Jianqun Huang ziyong liu Dong Department of Geotechnical Engineering Hunan University of Science and Technology Xiangtan Hunan 411201 China

The suitability of five methods was discussed here,taking the typical results from in-situ load test of Renshou Mansion and Caifu Plaza in Yueyang City for *** shows that bearing capacity can be obtained by the proportion load and limit load from p-s curve with the first and the second point of contraflexure *** is recommended that the accurate value of bearing capacity can be obtained by hyperbola fitting method and minimum curvature radius method *** rebound method is clear in principle,in which the elastoplasticity characteristic is thought *** of consideration for the unsteadiness and unobviousness of bearing capacity from relative settlement method,it can be only adopted as *** bearing capacity of soft rock ground should be determined by weathering condition of soft rock and curve type.

关键词： rock mechanics soft rock bearing capacity of ground in-situ load test of rock ground characteristic curve

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青霉木质纤维素降解酶系研究进展

应用与环境生物学报 2007年第5期13卷 736-740页

作者：孙宪昀曲音波刘自勇山东大学微生物技术国家重点实验室济南250100

越来越多的研究表明青霉属(Penicillium)真菌中的一些种类不仅能分泌组成齐全、酶活较高的木质纤维素降解酶系,而且具有易培养和生长快的优势.本文就国内外对青霉菌木质纤维素降解酶系研究的最新动态进行了综述,包括菌株的选育、纤维素... 详细信息

越来越多的研究表明青霉属(Penicillium)真菌中的一些种类不仅能分泌组成齐全、酶活较高的木质纤维素降解酶系,而且具有易培养和生长快的优势.本文就国内外对青霉菌木质纤维素降解酶系研究的最新动态进行了综述,包括菌株的选育、纤维素酶系的特性与合成调控,以及基因分析与克隆.同时介绍了斜卧青霉纤维素酶系的生产与发酵工艺,以及酶解过程分析等相关研究进展.

关键词：青霉纤维素酶合成调控基因克隆

斜卧青霉114-2 cbh1基因的TAIL-PCR克隆及与抗阻遏突变株JU-A10的比较

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微生物学报 2008年第5期48卷 667-671页

作者：刘自勇孙宪昀曲音波山东大学微生物技术国家重点实验室济南250100

【目的】研究斜卧青霉(Penicillium decumbens)114-2与其抗阻遏突变株JU-A10外切酶基因序列的差异。【方法】用热不对称交错PCR(TAIL-PCR)和RT-PCR扩增得到斜卧青霉114-2外切葡聚糖酶Ⅰ(cbh1)基因全长和cDNA全长。【结果】cbh1基因全长... 详细信息

【目的】研究斜卧青霉(Penicillium decumbens)114-2与其抗阻遏突变株JU-A10外切酶基因序列的差异。【方法】用热不对称交错PCR(TAIL-PCR)和RT-PCR扩增得到斜卧青霉114-2外切葡聚糖酶Ⅰ(cbh1)基因全长和cDNA全长。【结果】cbh1基因全长为1500bp,含有两个内含子,编码453个氨基酸(GenBank,EF397602)。克隆并分析了1.9kb的cbh1基因上游序列,分别发现了葡萄糖代谢抑制因子CREⅠ与纤维素酶转录调控蛋白ACEΙ的两个的潜在结合位点。【结论】在相同的培养条件下,其抗阻遏突变株JU-A10的外切酶活明显高于野生株114-2。两菌株的cbh1基因序列完全一致,说明外切酶活明显提高不是由于cbh1基因发生突变引起的。

关键词：斜卧青霉 TAIL-PCR cbh1 抗阻遏突变株

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近单晶硅密度液体压缩系数精密测量方法

仪器仪表学报 2014年第2期35卷 475-480页

作者：王金涛刘子勇佟林罗志勇李占宏中国计量科学研究院北京100013

近单晶硅密度液体(DSL-2329)广泛应用于单晶硅材料的高精密加工工艺中,其液体压缩系数准确测量对于单晶硅加工质量控制具有重要意义。为提高已有测量方法的精度,研究了一种基于单晶硅球静液悬浮原理的DSL-2329液体压缩系数测量方法。将... 详细信息

近单晶硅密度液体(DSL-2329)广泛应用于单晶硅材料的高精密加工工艺中,其液体压缩系数准确测量对于单晶硅加工质量控制具有重要意义。为提高已有测量方法的精度,研究了一种基于单晶硅球静液悬浮原理的DSL-2329液体压缩系数测量方法。将单晶硅球放置于充满DSL-2329液体的密闭容器内,通过改变DSL-2329液体的温度和静压力可以进行液体密度的微量调节,从而实现单晶硅球在液体中的静液悬浮。对于一个单晶硅球而言,可以在不同液体温度和静压力条件下实现静液悬浮,其中温度和静压力满足线性模型,测量出这个线性常数就可以计算出液体压缩系数。设计了单晶硅球静液悬浮测量系统,实现水浴温控系统在3 h之内可以保持在±1.0×10-4℃的范围内,通过PID控制系统调节静压力实现单晶硅球的静态悬浮。实验数据表明,由三溴丙烷和二溴乙烷组成的DSL-2329液体压缩系数为5.15×10-10Pa-1,验证了单晶硅球静液悬浮测量方法的有效性。

关键词：单晶硅球静液悬浮近硅密度液体压缩系数热膨胀系数测量

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某立交桥箱梁钢管支架设计与施工控制

辽宁交通科技 2005年第11期28卷 50-52页

作者：刘志勇石家庄铁道学院土木工程分院石家庄050043

以龙景互通立交桥1#桥预应力连续现浇箱梁为例,介绍了作为现浇箱梁承重支架的扣件式钢管支架计算和施工方法,从而保证桥梁现浇混凝土结构的施工。

关键词：箱梁扣件式钢管支架支架预压

大型油罐容量计量中3D空间建模方法研究与比对试验分析

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仪器仪表学报 2010年第2期31卷 421-425页

作者：王金涛刘子勇张珑郭立功暴雪松佟林中国计量科学研究院北京100013

油罐的容量计量是石化企业生产运行的核心工作之一。为了提高计量检定效率,提出一种基于三维激光扫描原理的油罐容量全自动测量方法。讨论了一种扫描点云数据分析方法,通过三角网格和曲面拟和的方法计算出不同液位高度对应的油罐容积值... 详细信息

油罐的容量计量是石化企业生产运行的核心工作之一。为了提高计量检定效率,提出一种基于三维激光扫描原理的油罐容量全自动测量方法。讨论了一种扫描点云数据分析方法,通过三角网格和曲面拟和的方法计算出不同液位高度对应的油罐容积值。设计了对比试验系统,选取60m3和37m3两个标准油罐为研究对象,根据OIMLR71和R80的技术要求,以0.025%准确度的容量比较法测量值为参考依据,三维激光扫描方法进行油罐容量测量具有好的复现性,而测得的容量值相对偏差满液位量程处可达0.4%,验证了这种方法的有效性,而且有效提高了油罐容量检定工作效率。

关键词：油罐容量计量 3D空间建模方法比对试验