检索结果-南通市图书馆

Respiratory manifestations in amyloidosis

Chinese Medical Journal 2005年第24期118卷 2027-2033页

作者： XU Ling CAI Bai-qiang ZHONG Xu zhu yuan-jue Department of Respiratory Medicine Peking Union Medical CollegeHospital Peking Union Medical College Chinese Academy ofMedical Sciences Beijing 100730 China

Background Amyloidosis is a collection of diseases in which different proteins are deposited. Amyloid deposits occur in systemic and organ-limited forms. In both systemic and localized forms of the disease, lung can he involved. The aim of this study was to explore the different respiratory manifestations of amyloidosis. Methods Chest radiology, clinical presentations, bronchoscopic/laryngoscopic findings and lung function data of 59 patients with amyloidosis involving respiratory tract collected during January 1986 to March 2005, were analysed. Results Of the 16 cases with localized respiratory tract amyloidosis, 8 had the lesions in the trachea and the bronchi, 2 in the larynx and the trachea, 5 in the larynx and/or the pharynx, and 1 in the lung parenchyma. Of 43 systemic amyloidosis with respiratory tract involvement, 3 had the lesions in bronchi, 13 in lung parenehyma, 33 in pleura, 8 in mediastina, 1 in nose and 1 in pharynx. Chest X-rays were normal in most cases of tracheobronchial amyloidosis. CT, unlike chest X-rays, showed irregular luminal narrowing, airway wall thickening with calcifications and soft tissue shadows in airway lumen. Localized lung parenchymal amyloidosis presented as multiple nodules. Multiple nodular opacities, patch shadows and reticular opacities were the main radiological findings in systemic amyloidosis with lung parenchymal involvement. In pleural amyloidosis, pleural effusions and pleural thickening were detected. Mediastinal and/or hilar adenopathy were also a form of lung involvement in systemic amyloidosis. The major bronehoseopie findings of tracheobronchial amyloidosis were narrowing of airway lumen, while nodular, ＇ tumour like＇ or ＇ bubble like＇ masses, with missing or vague cartilaginous rings, were detected in about half of the patients. Conclusions Localized respiratory tract amyloidosis mostly affects the trachea and the bronchi. Chest X-rays are not sensitive to detect these lesions. Systemic amyloidosis often invo

关键词： amyloiclosis trachea bronchus lung pleural effusion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical parameters and outcomes of Pneumocystis jiroveci pneumonia in non-HIV/AIDS patients

引用

Chinese Medical Journal 2006年第3期119卷 234-237页

作者： CAO Bin WANG Hui WANG Peng LI Meng-tao zhu yuan-jue Department of Pulmonary Medicine Chinese Academy of MedicalSciences Peking Union Medical College Hospital Beijing 100730China Department of Microbiology Chinese Academy of Medical~ciences Peking Union Medical College Hospital Beijing 100730China Department of Reumotology Chinese Academy of MedicalSciences Peking Union Medical College Hospital Beijing 100730China

Pneumocystis jiroveci pneumonia （PCP） is one of the most serious and potentially fatal infectionsencountered in immonosuppressed patients. It remains the most common cause of pulmonary morbidity and mortality in pat... 详细信息

关键词： Pneumocystis jiroveci pneumonia connective tissue disease human immunodeficiency virus corticosteroid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Modification of Maxwell model for conductivity prediction of carbon nanotubes-filled polymer composites with tunneling effect

引用

Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 25-36页

作者： jue zhu Longyuan LI Ningtao zhu Zhejiang Provincial Engineering Research Center for the Safety of Pressure Vessel and Pipeline Key Laboratory of Impact and Safety Engineering (Ningbo University) Ministry of Education School of Engineering Computing and Mathematics University of Plymouth Xi'an Zhanshi Testing & Engineering Co.Ltd.

Carbon nanotubes(CNTs) have garnered great attention in recent years due to their outstanding electrical, thermal, and mechanical properties. The incorporation of small amounts of CNTs in polymers can substantially improve the sensitivity of the polymer's electrical conductivity. This paper presents a modified Maxwell model to evaluate the electrical conductivity of CNTs-filled polymer composites by introducing a transition zone to account for the tunneling effect. In this modified Maxwell model, the CNTs-filled polymer composite is modeled as a three-phase composite, consisting of a matrix(polymer), inclusions(CNTs), and a transition zone(tunneling zone). The effective electrical conductivity(EEC) of the composite is calculated based on the volume fractions and electrical conductivities of the matrix, inclusions, and transition zone. The model's validity is confirmed through the use of available test data, which demonstrates its capability to accurately capture the nonlinear conductivity behavior observed in CNTs-polymer composites. This study offers valuable insights into the design of high-performance conductive polymer nanocomposites, and enhances the understanding of electrical conduction mechanisms in CNT-dispersed polymer composites.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Multiple dimensions of cardiopulmonary dyspnea

引用

Chinese Medical Journal 2011年第20期124卷 3220-3226页

作者： HAN Jiang-na XIONG Chang-ming YAO Wei FANG Qiu-hong zhu yuan-jue CHENG Xian-sheng Karel P Van de Woestijne Department of Pneumology Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100730 China Pulmonary Vascular Disease Center Fu Wai Hospital and Cardiovascular Institute Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100037 China Department of Respiratory Diseases Xinqiao Hospital Third Military Medical University Chongqing 400037 China Department of Respiratory Medicine Beijing Shijitan Hospital Peking University Beijing 100038 China Department of Pneumology U Z Gasthuisberg B-3000 Leuven Belgium

Background The current theory of dyspnea perception presumes a multidimensional conception of dyspnea. However, its validity in patients with cardiopulmonary dyspnea has not been investigated. Methods A respiratory symptom checklist incorporating spontaneously reported descriptors of sensory experiences of breathing discomfort, affective aspects, and behavioral items was administered to 396 patients with asthma, chronic obstructive pulmonary disease （COPD）, diffuse parenchymal lung disease, pulmonary vascular disease, chronic heart failure, and medically unexplained dyspnea. Symptom factors measuring different qualitative components of dyspnea were derived by a principal component analysis. The separation of patient groups was achieved by a variance analysis on symptom factors. Results Seven factors appeared to measure three dimensions of dyspnea： sensory （difficulty breathing and phase of respiration, depth and frequency of breathing, urge to breathe, wheeze）, affective （chest tightness, anxiety）, and behavioral （refraining from physical activity） dimensions. Difficulty breathing and phase of respiration occurred more often in COPD, followed by asthma （R2=0.12）. Urge to breathe was unique for patients with medically unexplained dyspnea （R2=0.12）. Wheeze occurred most frequently in asthma, followed by COPD and heart failure （R2=0.17）. Chest tightness was specifically linked to medically unexplained dyspnea and asthma （R2=0.04）. Anxiety characterized medically unexplained dyspnea （R2=0.08）. Refraining from physical activity appeared more often in heart failure, pulmonary vascular disease, and COPD （R2=0.15）. Conclusions Three dimensions with seven qualitative components of dyspnea appeared in cardiopulmonary disease and the components under each dimension allowed separation of different patient groups. These findings may serve as a validation on the multiple dimensions of cardiopulmonary dyspnea.

关键词： breathlessness respiratory disease cardiovascular disease

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fearful imagery induces hyperventilation and dyspnea in medically unexplained dyspnea

引用

Chinese Medical Journal 2008年第1期121卷 56-62页

作者： HAN Jiang-na zhu yuan-jue LUO Dong-mei LI Shun-wei Ilse Van Diest Omer Van den Bergh KarelP Van de Woestijne Department of Pneumology Peking Union Medical CollegeHospital Chinese Academy of Medical Sciences Beijing 100730China Department of Psychology University of Leuven B-3000 LeuvenBelgium Department of Pneumology U Z Gasthuisberg B-3000 LeuvenBelgium

Background Medically unexplained dyspnea refers to a condition characterized by a sensation of dyspnea and is typically applied to patients presenting with anxiety and hyperventilation without underlying cardiopulmonary pathology. We were interested to know how anxiety triggers hyperventilation and elicits subjective symptoms in those patients. Using an imagery paradigm, we investigated the role of fearful imagery in provoking hyperventilation and in eliciting symptoms, specifically dyspnea. Methods Forty patients with medically unexplained dyspnea and 40 normal subjects matched for age and gender were exposed to scripts and asked to imagine both fearful and restful scenarios, while end-tidal PCO2 （PetCO2） and breathing frequency were recorded and subjective symptoms evaluated. The subject who had PetCO2 falling more than 5 mmHg from baseline and persisting at this low level for more than 15 seconds in the imagination was regarded as a hyperventilation responder. Results In patients with medically unexplained dyspnea, imagination of fearful scenarios, being blocked in an elevator in particular, induced anxious feelings, and provoked a significant fall in PetCO2 （P〈0.05）. Breathing frequency tended to increase. Eighteen out of 40 patients were identified as hyperventilation responders compared to 5 out of 40 normal subjects （P〈0.01）. The patients reported symptoms of dyspnea, palpitation or fast heart beat in the same fearful script imagery. Additionally, PetCO2 fall was significantly correlated with the intensity of dyspnea and palpitation experienced during the mental imagery on one hand, and with anxiety symptoms on the other. Conclusions Fearful imagery provokes hyperventilation and induces subjective symptoms of dyspnea and palpitation in patients with medically unexplained dyspnea.

关键词： medically unexplained dyspnea hyperventilation anxiety dyspnea mental imagery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

特发性间质性肺炎临床研究的新动向

引用

中华结核和呼吸杂志 2007年第4期30卷 241-242页

作者：康健朱元珏中国医科大学附属第一医院呼吸疾病研究所沈阳110001 中国医学科学院中国协和医科大学北京协和医院呼吸内科

特发性间质性肺炎（idiopathic interstitial pneumonias，IIP）是病因不明的一组间质性肺疾病的总称。2002年，美国胸科学会和欧洲呼吸学会（ATS／ERS）发表的多学科国际性共识报告中，根据临床、影像学、病理的特点将其分为7个亚型。... 详细信息

特发性间质性肺炎（idiopathic interstitial pneumonias，IIP）是病因不明的一组间质性肺疾病的总称。2002年，美国胸科学会和欧洲呼吸学会（ATS／ERS）发表的多学科国际性共识报告中，根据临床、影像学、病理的特点将其分为7个亚型。近几年，国内外学者对IIP分类本身以及IIP中最具代表性的疾病——特发性肺纤维化（IPF）／普通型间质性肺炎（usual interstitial pneumonia，UIP）进行了深入的研究并取得一定的进展，使人们感到，在本研究领域新的认识与争议并存；在IPF的药物治疗方面，困境与希望同在。

关键词：特发性间质性肺炎临床研究普通型间质性肺炎间质性肺疾病特发性肺纤维化欧洲呼吸学会美国胸科学会

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

老年人肺癌的临床特点

引用

中华老年医学杂志 1991年第1期10卷 8-11页

作者：张丹朱元珏北京协和医院内科 100730

分析了经病理、细胞学确诊的51例60～86岁肺癌患者的临床表现与治疗，并与同期116例26～59岁肺癌患者进行比较。结果表明：老年组胸痛、发热和肺部体征的出现率低于非老年组（P﹤0.05）；老年组鳞状细胞癌和肺泡细胞癌所占百分比高于非... 详细信息

分析了经病理、细胞学确诊的51例60～86岁肺癌患者的临床表现与治疗，并与同期116例26～59岁肺癌患者进行比较。结果表明：老年组胸痛、发热和肺部体征的出现率低于非老年组（P﹤0.05）；老年组鳞状细胞癌和肺泡细胞癌所占百分比高于非老年组（P﹤0.05），老年组患者合并症和并发症显著高于非老年组，尤以心血管和呼吸系统疾病为多。两组在X线表现、获取病理学标本方法、TNM分期、治疗方法以及即刻治疗效果等方面差异无显著性。因此，对老年肺癌患者的治疗应持积极的态度。

关键词：肺肿瘤老年人

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

太赫兹波段Smith-Purcell辐射的介质加载光栅高频特性

引用

物理学报 2016年第1期65卷 69-77页

作者：曹苗苗刘文鑫王勇朱觉远李科中国科学院电子学研究所中国科学院高功率微波源与技术重点实验室北京100190 中国科学院大学北京100049

提出了一种用于Smith-Purcell效应器件的介质加载光栅慢波结构,通过研究该结构的注-波互作用过程,推导出带电子注的色散方程,并数值求解出波的线性增长率.利用色散方程,结合电磁场传播的边界条件,推导出Smith-Purcell效应振荡器工作所... 详细信息

提出了一种用于Smith-Purcell效应器件的介质加载光栅慢波结构,通过研究该结构的注-波互作用过程,推导出带电子注的色散方程,并数值求解出波的线性增长率.利用色散方程,结合电磁场传播的边界条件,推导出Smith-Purcell效应振荡器工作所需的起振电流.详细研究了高频结构长度、电子注主要参数和介质相对介电常数对起振电流的影响,并与普通金属光栅结构进行了比较.结果表明:保持其他参数不变时,高频结构长度越短,起振电流越大;保持高频结构参数不变时,起振电流随电子注厚度和注-栅距离的增大而增大,随电子注电压的增大而减小;与金属光栅相比,介质的引入提高了注-波互作用的增长率,有效减小了振荡器的起振电流.理论计算结果与软件CHIPIC的模拟结果比较符合.

关键词：介质加载光栅慢波结构色散方程增长率起振电流

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

气道中心性间质纤维化的诊断及鉴别诊断

引用

中国医学科学院学报 2005年第1期27卷 99-102,F003页

作者：徐凌蔡柏蔷刘鸿瑞朱元珏中国医学科学院中国协和医科大学北京协和医院呼吸科北京100730

目的介绍一种新近发现的特发性间质性肺炎——气道中心性间质纤维化及其鉴别诊断。方法分析北京协和医院确诊的1例以及文献报道的12例气道中心性间质纤维化患者的临床表现、肺功能、支气管肺泡灌洗液、影像学及病理学特点。结果气道中... 详细信息

目的介绍一种新近发现的特发性间质性肺炎——气道中心性间质纤维化及其鉴别诊断。方法分析北京协和医院确诊的1例以及文献报道的12例气道中心性间质纤维化患者的临床表现、肺功能、支气管肺泡灌洗液、影像学及病理学特点。结果气道中心性间质纤维化患者主要表现为慢性咳嗽和缓慢进展的呼吸困难,肺功能表现为限制性通气功能障碍,支气管肺泡灌洗液多有淋巴细胞增加,影像学表现为弥漫性网状结节影,伴气道壁增厚及周围纤维化,病理表现为明显的以膜性和呼吸性细支气管为中心的间质纤维化。结论气道中心性间质纤维化不同于其他间质性肺病,但其是否为一个独特的疾病有待进一步明确。

关键词：细支气管炎间质性肺病小气道疾病纤维化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

淋巴细胞性间质性肺炎三例并文献复习

引用

中华内科杂志 2006年第4期45卷 293-297页

作者：徐凌许文兵蔡柏蔷朱元珏中国医学科学院中国协和医科大学北京协和医院呼吸科 100730

目的通过分析3例淋巴细胞性间质性肺炎(LIP),探讨LIP的病因、诊断及鉴别诊断。方法回顾性分析我院确诊的3例LIP患者的临床特点,并结合文献报道加以总结。结果(1)LIP常与自身免疫性疾病和免疫缺陷相关,起病缓慢,主要表现为进行性咳嗽和... 详细信息

目的通过分析3例淋巴细胞性间质性肺炎(LIP),探讨LIP的病因、诊断及鉴别诊断。方法回顾性分析我院确诊的3例LIP患者的临床特点,并结合文献报道加以总结。结果(1)LIP常与自身免疫性疾病和免疫缺陷相关,起病缓慢,主要表现为进行性咳嗽和呼吸困难,双肺底听诊可闻及爆裂音,肺功能常表现为限制性通气功能障碍伴弥散功能受损。(2)高分辨率CT表现为边界不清的小叶中央性结节和胸膜下小结节、磨玻璃样影,支气管血管束增厚、小叶间隔增厚及囊状气腔。(3)支气管肺泡灌洗液中淋巴细胞增多。(4)病理表现为弥漫性肺间质致密淋巴细胞浸润,淋巴细胞呈多克隆性。结论特发性LIP罕见,若要确诊应进行全面检查以明确有无任何已知的病因或相关疾病。

关键词：肺疾病间质性肺纤维化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：