检索结果-南通市图书馆

同方期刊数据库

在线全文

学校读者我要写书评

暂无评论

臭氧催化氧化水中PPCPs的研究进展

广州化工 2024年第12期52卷 98-100,121页

作者：朱羽廷乔俊莲同济大学建筑设计研究院(集团)有限公司上海200092 同济大学环境科学与工程学院上海200092

由于药物及个人护理品(Pharmaceutical and Personal Care Products,PPCPs)在环境中的持久性或伪持久性特征,会对生物体造成严重危害。然而PPCPs种类复杂,性质各异,常规水处理工艺的去除率不足10%。臭氧氧化能力强,反应速度快、无二次污... 详细信息

由于药物及个人护理品(Pharmaceutical and Personal Care Products,PPCPs)在环境中的持久性或伪持久性特征,会对生物体造成严重危害。然而PPCPs种类复杂,性质各异,常规水处理工艺的去除率不足10%。臭氧氧化能力强,反应速度快、无二次污染,但反应过程中存在臭氧利用率低、反应不彻底等缺点。在臭氧氧化体系中加入催化剂,从而提高了PPCPs的降解效率成为重要的研究方向。根据投加催化剂的存在状态,对臭氧催化氧化进行了总结和展望。

关键词：臭氧催化 PPCPs 均相非均相催化机理

基于按病种付费医保支付方式改革的医院信息化探索

在线全文

学校读者我要写书评

暂无评论

中国医疗器械信息 2024年第11期30卷 35-39页

作者：刘晓娇朱玉婷鲍瀛南京鼓楼医院信息管理处江苏南京210008

目的:建设按病种付费(DRGs)信息系统,提高病历入组率,促进医院提高资源利用效率,提升医院质量管理水平。方法:基于一体化信息平台,构建院端分组器引擎,对病案进行智能校验,实现精确预测分组,完成诊断、手术等编码的映射,改善临床病历书... 详细信息

目的:建设按病种付费(DRGs)信息系统,提高病历入组率,促进医院提高资源利用效率,提升医院质量管理水平。方法:基于一体化信息平台,构建院端分组器引擎,对病案进行智能校验,实现精确预测分组,完成诊断、手术等编码的映射,改善临床病历书写质量,完成数据的精细化治理和质控,实现病案数据的准确上传和入组,同时提供DRGs分组智能查询,方便管理部门及时监管。结果:借助信息化手段,切实保证病历的书写、归档、编码、上传、入组等全流程管理,并支持数据智能分析功能。对比系统上线前后,病案首页七日上传率、病例组合指数、时间消耗指数以及费用消耗指数得到显著改善,平均住院天数及低风险病死率显著降低。结论:DRGs医保支付方式改革的信息化探索,有助于本院在医保政策下开展有效引导院内DRGs管理及合理控费途径。同时,为管理部门以及临床医院提供决策支持,助力医院高质量发展。

关键词：按病种付费信息化病案首页数据治理控费

在线全文

学校读者我要写书评

暂无评论

注射用交联透明质酸钠凝胶生物相容性研究

中国医疗器械信息 2024年第3期30卷 39-42页

作者：王丽洁梁羽朱雨婷孙国伟苏州苏大卫生与环境技术研究所有限公司江苏苏州215123

目的:评价注射用交联透明质酸钠凝胶的生物相容性。方法:分别通过细胞毒性试验、致敏试验、皮内反应试验、急性毒性试验、遗传毒性试验、植入试验、慢性毒性试验来全面评价注射用交联透明质酸钠凝胶的生物相容性。结果:试验结果显示,注... 详细信息

目的:评价注射用交联透明质酸钠凝胶的生物相容性。方法:分别通过细胞毒性试验、致敏试验、皮内反应试验、急性毒性试验、遗传毒性试验、植入试验、慢性毒性试验来全面评价注射用交联透明质酸钠凝胶的生物相容性。结果:试验结果显示,注射用交联透明质酸钠凝胶对L929细胞有轻度细胞毒性、无致敏反应、无遗传毒性、无急性和慢性毒性反应、皮内反应记分为1.5,植入试验4、13、26、52周各阶段评分为3.08、1.83、0.33、0,52周基本完成降解。结论:该注射用交联透明质酸钠凝胶对局部组织有轻微不良反应,但未发现全身毒性和遗传毒性影响。

关键词：交联透明质酸钠凝胶生物相容性毒性

Silencing of Jumonji domain-containing 1C inhibits the osteogenic differentiation of bone marrow mesenchymal stem cells via nuclear factor-κB signaling

在线全文

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2024年第2期16卷 151-162页

作者： Jing-Yi Li ting-ting Wang Li Ma yu Zhang Di zhu Department of Medical Cosmetology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Department of General Gerontology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina Department of Plastic Surgery China-Japan Friendship HospitalBeijing 100029China Senior Department of Hematology The Fifth Medical CentreGeneral Hospital of Chinese People’s Liberation ArmyBeijing 100071China Department of Orthopaedic Surgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China

BACKGROUND Osteoporosis is a common metabolic bone disorder induced by an imbalance between osteoclastic activity and osteogenic *** osteoporosis,bone mesenchymal stem cells(BMSCs)exhibit an increased ability to differentiate into adipocytes and a decreased ability to differentiate into osteoblasts,resulting in bone *** domain-containing 1C(JMJD1C)has been demonstrated to suppress *** To examine the effect of JMJD1C on the osteogenesis of BMSCs and the potential underlying *** BMSCs were isolated from mouse bone marrow *** Red O staining,Alizarin red staining,alkaline phosphatase staining and the expression of adipo-genic and osteogenic-associated genes were assessed to determine the differen-tiation of *** marrow-derived macrophages(BMMs)were incubated with receptor activator of nuclear factor-kappaΒligand to induce osteoclast differentiation,and osteoclast differen-tiation was confirmed by tartrate-resistant acid phosphatase *** related genes were measured via reverse transcription coupled to the quantitative polymerase chain reaction and western ***-linked immunosorbent assays were used to measure the levels of inflammatory cytokines,including tumor necrosis factor alpha,interleukin-6 and interleukin-1 *** The osteogenic and adipogenic differentiation potential of BMSCs isolated from mouse bone marrow samples was ***1C mRNA and protein expression was upregulated in BMSCs after osteoblast induction,while p-nuclear factor-κB(NF-κB)and inflammatory cytokines were not significantly *** of JMJD1C repressed osteogenic differentiation and enhanced NF-κB activation and inflammatory cytokine release in ***,JMJD1C expression decreased during BMM osteoclast *** The JMJD1C/NF-κB signaling pathway is potentially involved in BMSC osteogenic differentiation and may play vital roles in the pathogenesis of osteoporosis.

关键词： Osteoporosis Mesenchymal stem cells Osteogenesis Jumonji domain-containing 1C Nuclear factor-κB

Strip flatness prediction of cold rolling based on ensemble methods

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research(International) 2024年第1期31卷 237-251页

作者： Wu-quan Yang Zhi-ting Zhao Liang-yu zhu Xun-yang Gao Li Wang School of Mechanical and Power Engineering Shenyang University of Chemical TechnologyShenyang110142LiaoningChina

Aiming at the problem of insufficient prediction accuracy of strip flatness at the outlet of cold tandem rolling,the prediction performance of strip flatness based on different ensemble methods was studied and a high-precision prediction ensemble model of strip flatness at the outlet was ***,based on linear regression(LR),K nearest neighbors(KNN),support vector regression,regression trees(RT),and backpropagation neural network(BPN),bagging,boosting,and stacking ensemble methods were used for ensemble ***,three existing ensemble models,i.e.,random forest,extreme random tree(ET)and extreme gradient boosting,were used to conduct experiments and compare the *** research shows that bagging,boosting,and stacking three ensemble methods have the most significant improvement in the prediction accuracy of the regression trees model,which is increased by 5.28%,6.51%,and 5.32%,*** the same time,the stacking ensemble method improves both the simple model and the complex model,and the improvement effect on the simple base model is the greatest,which is 4.69%higher than that of the base model *** all of the ensemble models,the stacking ensemble model of level-1(ET,AdaBoost-RT,LR,BPN)paired with level-2(LR)was discovered to be the best model(EALB-LR)and can be further studied for industrial applications.

关键词： Tandem cold rolling Flatness prediction Machine learning Ensemble method

苏黄止咳胶囊联合胸腺肽治疗老年慢阻肺合并肺部感染患者效果及对免疫功能、血气指标的影响

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

现代生物医学进展 2024年第11期24卷 2099-2103页

作者：武蕊姚彦王星朱玉婷黄牧坤丁健超西安交通大学医学部附属三二〇一医院药学部陕西汉中723000 空第九八六医院检验病理科陕西西安710038 西安交通大学第一附属医院检验科陕西西安710089 陕西省结核病防治院药剂科陕西西安710100

目的:探讨苏黄止咳胶囊联合胸腺肽治疗老年慢阻肺合并肺部感染患者效果及对免疫功能、血气指标的影响。方法:将80例于医院进行治疗的老年患者作为研究对象,患者均确诊为慢阻肺疾病,且均合并肺部感染。患者入院时间分布在2020年9月至2023... 详细信息

目的:探讨苏黄止咳胶囊联合胸腺肽治疗老年慢阻肺合并肺部感染患者效果及对免疫功能、血气指标的影响。方法:将80例于医院进行治疗的老年患者作为研究对象,患者均确诊为慢阻肺疾病,且均合并肺部感染。患者入院时间分布在2020年9月至2023年9月范围内,根据治疗方式的不同对患者进行分组,其中40例患者分为对照组,在常规对症治疗基础上增加胸腺肽治疗,另外40例患者分为观察组,在对照组基础上增加苏黄止咳胶囊治疗。对比两组临床治疗总有效率、炎性因子[C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)]、免疫功能[CD3^(+)、CD4^(+)/CD8^(+)、自然杀伤细胞(NK)]、血气指标[二氧化碳分压(PaCO_(2))、动脉血氧分压(PaO_(2))、酸碱度(pH)]、不良反应发生情况[恶心呕吐、头晕、皮疹、腹泻]。结果:观察组治疗总有效率高于对照组(P0.05)。结论:老年慢阻肺合并肺部感染患者在常规对症治疗和胸腺肽治疗的基础上增加苏黄止咳胶囊治疗,可明显提升临床治疗总有效率,改善炎性因子水平和血气指标,提升免疫功能,且不会增加不良反应发生风险。

关键词：苏黄止咳胶囊胸腺肽老年慢阻肺肺部感染

Boosting thermal stability and crystallization of closed-loop-recyclable biodegradable poly(p-dioxanone) by end-group regulation

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第2期67卷 642-651页

作者： Jin Lei zhu-Xin Gui Wan-ting Xiong Gang Wu Si-Chong Chen yu-Zhong Wang The Collaborative Innovation Center for Eco-Friendly and Fire-Safety Polymeric Materials(MoE) National Engineering Laboratory of Eco-Friendly Polymeric Materials(Sichuan)State Key Laboratory of Polymer Materials EngineeringCollege of ChemistrySichuan UniversityChengdu610064China

A chemically closed-loop-recyclable biodegradable polymer,poly(p-dioxanone)(PPDO),is one of the ideal candidates for single-use plastic products due to its suitability for different application ***,when PPDO wastes can be collected,its monomer p-dioxanone(PDO) will be obtained through chemical recycling of these wastes;when cannot be collected,the wastes are able to be biodegraded into harmless ***,unsatisfied thermal stability and low crystallization rate of PPDO restrict its wider ***,based on end-group regulation,we simultaneously realized the significant enhancement of thermal stability and crystallization of PPDO through the simple melt processing with tributyl phosphite(TBP) or triphenyl phosphite(TPP).The model reactions were conducted to investigate the reaction mechanism and theoretical products during the preparation of PPDO/phosphite *** kinds of phosphites were proved to act as the end-capped reagent and chain extender in the melt processing,while TBP presented better *** a result,the activation energy of thermal decomposition was largely elevated,and the unprecedented T_(5%)(the temperature at a weight loss of 5%) and Tmax(the temperature at a maximum rate of weight loss) of PPDO were obtained,i.e.,T_(5%)of ~330 ℃ and Tmaxof ~385 ℃ in N_(2) atmosphere,T_(5%)of ~240 ℃ and Tmaxof ~317 ℃ in air atmosphere,***,the increased crystallization rate,crystallinity,crystalline orderliness,and realizable monomer recovery(yield >90%,purity >99.9%) of PPDO/phosphite compounds were confirmed.

关键词： poly(p-dioxanone) phosphite thermal stability crystallization end-group regulation

Laryngopharyngeal reflux disease:Updated examination of mechanisms,pathophysiology,treatment,and association with gastroesophageal reflux disease

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第16期30卷 2209-2219页

作者： Na Cui ting Dai Yang Liu Ya-yu Wang Jia-yu Lin Qing-Fan Zheng Dong-Dong zhu Xue-Wei zhu Department of Otorhinolaryngology Head and Neck Surgery China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Ultrasound China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Gastroenterology China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

Laryngopharyngeal reflux disease(LPRD)is an inflammatory condition in the laryngopharynx and upper aerodigestive tract mucosa caused by reflux of stomach contents beyond the *** commonly presents with symptoms such as hoarseness,cough,sore throat,a feeling of throat obstruction,excessive throat *** complex condition is thought to involve both reflux and reflex mechanisms,but a clear understanding of its molecular mechanisms is still ***,there is no standardized diagnosis or treatment *** strategies for LPRD mainly include lifestyle modifications,proton pump inhibitors and endoscopic *** paper seeks to provide a comprehensive overview of the existing literature regarding the mechanisms,pathophysiology and treatment of *** also provide an in-depth exploration of the association between LPRD and gastroesophageal reflux disease.

关键词： Laryngopharyngeal reflux Gastroesophageal reflux Head neck surgery Laryngitis Otolaryngology

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于YOLOv3的风机叶片故障检测模型

化工自动化及仪表 2024年第3期51卷 487-494页

作者：朱玉廷汪怡然马锦雄谢鹏陆鹏汤占军山子岐昆明理工大学信息工程与自动化学院云南龙源新能源有限公司

针对风机工作中由于高海拔地理位置、恶劣天气等因素的影响,致使风机叶片出现裂纹、沙眼等缺陷故障,提出基于YOLOv3算法的风机叶片故障检测模型。将风机叶片缺陷区域具有YOLO格式的数据集划分为训练集与测试集,输入YOLOv3模型进行实验,... 详细信息

针对风机工作中由于高海拔地理位置、恶劣天气等因素的影响,致使风机叶片出现裂纹、沙眼等缺陷故障,提出基于YOLOv3算法的风机叶片故障检测模型。将风机叶片缺陷区域具有YOLO格式的数据集划分为训练集与测试集,输入YOLOv3模型进行实验,结果表明:YOLOv3模型与YOLOv2模型相比,精度提升3.7%,达到了90.6%;召回率提升3.2%,达到了90.5%;精度平均值提升4.8%,达到了76.2%。

关键词： YOLOv3算法故障检测风机叶片数据集精度平均值