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Chinese Medical Journal 2014年第4期127卷 675-679页

作者： xu Haifeng Yang Renjie Wang Xiaodong zhu xu Chen hui Department of Interventional Therapy Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer Hospital &amp Institute Beijing 100142China

Background Pulmonary lipiodol embolism after transarterial chemoembolization （TACE） was rare and life-threatening,occasionally reported in previous *** aimed to review the records of 11 patients with pulmonary oily embolism and analyze their characteristics of radiographic findings and risk *** Records of 478 consecutive patients who underwent 1 026 percutaneous TACE procedures were retrospectively *** cases with respiratory symptoms were identified as having symptomatic pulmonary lipiodol embolism after *** of these patients,including clinical presentation,techniques of TACE,imaging features of tumor and chest imaging findings,were *** Eleven （2.3%） of 478 consecutive patients who underwent percutaneous TACE procedures had a pulmonary oily embolism after *** mean size of target tumors embolized was （13.6＆#177;2.0） *** were *** mean volume of lipiodol was （21.8＆#177;8.2） *** oily embolisms were revealed within 12-48 hours after *** most severe respiratory symptoms and imaging abnormalities of the eight patients who survived presented between 2 and 5 days after TACE,becoming normal between 12 and 35 days after *** patients *** CT revealed retention of radiopaque lipiodol in *** Pulmonary lipiodol embolism occurs easily in patients who have large hyper-vascular hepatic malignant *** high-density lipiodol deposition in the lung field can be used as diagnostic feature.

关键词： lipiodol pulmonary embolism hepatic tumor complications transarterial chemoembolization

Dietary Patterns Associated Metabolic Syndrome in Chinese Adults

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Biomedical and Environmental Sciences 2015年第5期28卷 370-373页

作者： HE Deng Hua YANG Min ZHANG Rong Hua MA Xiao Guang HUANG Li Chun HUANG En Shan GU Wei zhu Yi Bo ZHAO Dong zhu xu hui DING Gang Qiang ZHOU Biao Department of Nutrition and Food Hygiene Medical School of Ningbo University Department of Nutrition and Food Hygiene Zhejiang University School of Public Health Zhejiang Provincial Center for Disease Control and Prevention

Dietary pattern has been revealed to be associated with metabolic syndrome. However, the association was not well documented in Chinese due to the complexity of Chinese foods. We mainly assessed the dietary patterns and examined their effects on metabolic syndrome among Chinese adults. Four dietary patterns including ＇Refined Grains ＆ Vegetables＂ Pattern, ＇Dairy ＆ Eggs＇ Pattern, ＇Organ Meat ＆ Poultry＇ Pattern, and ＇Coarse Grains ＆ Beans＇ Pattern were extracted. ＇Dairy ＆ Eggs＇ Pattern was associated with a decreased odds of metabolic syndrome in women, and ＇Coarse Grains ＆ Beans＇ Pattern was associated with a decreased odds of hypertension in men. These results provided a scientific basis for future research and dietarv euideline Perfection.

关键词： Dietary Patterns Associated Metabolic Syndrome in Chinese Adults FBG HDL

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阻尼孔活塞粉末冶金产品开发与模具设计

模具工业 2007年第7期33卷 65-67页

作者：朱旭晖株洲职业技术学院机械工程系湖南株洲412000

通过对产品使用性能的合理分析,运用粉末冶金成形原理,在压制毛坯时一次性将阻尼孔压制成形,对烧结后的毛坯采用精整工艺,控制零件关键尺寸精度与形位公差,辅以适当的机械加工工序,在自动模上成功地开发了细孔类粉末冶金结构件,与其他... 详细信息

通过对产品使用性能的合理分析,运用粉末冶金成形原理,在压制毛坯时一次性将阻尼孔压制成形,对烧结后的毛坯采用精整工艺,控制零件关键尺寸精度与形位公差,辅以适当的机械加工工序,在自动模上成功地开发了细孔类粉末冶金结构件,与其他工艺相比,零件尺寸稳定,提高了生产率,降低了生产成本,取得了良好的经济效益。

关键词：粉末冶金减震活塞成形全整型

Rock fracture mechanism of buffer blasting with cushion layer at the borehole bottom

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 325-334页

作者： Xinguang zhu Chenxi Ding Zhe Sui Hong Su xu Guo School of Civil and Resources Engineering University of Science and Technology BeijingBeijing 100083China Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing 100190China School of Mechanics and Civil Engineering China University of Mining and Technology(Beijing)Beijing 100083China School of Chemical and Blasting Engineering Anhui University of Science and TechnologyHuainan 232001China

This study primarily investigates the rock fracture mechanism of bottom cushion layer blasting and explores the effects of the bottom cushion layer on rock *** involves analyses of the evolution patterns of blasting stress,characteristics of crack distribution,and rock fracture features in the ***,blasting model experiments were carried out using the dynamic caustics principle to investigate the influence of bottom cushion layers and initiation methods on the integrity of the bottom rock *** experimental results indicate that the combined use of bottom cushion layers and inverse initiation effectively protects the integrity of the bottom rock ***,the process of stress wave propagation and dynamic crack propagation in rocks was simulated using the continuum-discontinuum element method(CDEM)and the Landau explosion source model,with varying thicknesses of bottom cushion *** numerical simulation results indicate that with increasing cushion thickness,the absorption of energy generated by the explosion becomes more pronounced,resulting in fewer cracks in the bottom rock *** illustrates the positive role of the cushion layer in protecting the integrity of the bottom rock mass.

关键词： bottom cushion layer blasting crack propagation continuum-discontinuum element method dynamic stress intensity factor

EZH2-dependent myelination following sciatic nerve injury

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Neural Regeneration Research 2025年第8期20卷 2382-2394页

作者： hui zhu Li Mu Xi xu Tianyi Huang Ying Wang Siyuan xu Yiting Wang Wencong Wang Zhiping Wang Hongkui Wang Chengbin xue Research Center of Clinical Medicine Affiliated Hospital of Nantong UniversityKey Laboratory of Neuroregeneration of Jiangsu and Ministry of EducationCo-innovation Center of NeuroregenerationNMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology ProductsNantong UniversityNantongJiangsu ProvinceChina Medical School of Nantong University NantongJiangsu ProvinceChina Department of Neurology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Department of Rehabilitation Medicine Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Department of Critical Care Medicine Nantong Fourth People’s HospitalNantongJiangsu ProvinceChina

Demyelination and remyelination have been major focal points in the study of peripheral nerve regeneration following peripheral nerve ***,the gene regulatory network of regenerated myelin differs from that of native *** of enhancer of zeste homolog 2(EZH2)hinders the differentiation,maturation,and myelination of Schwann cells in *** further determine the role of EZH2 in myelination and recovery post-peripheral nerve injury,conditional knockout mice lacking Ezh2 in Schwann cells(Ezh2^(fl/fl);Dhh-Cre and Ezh2^(fl/fl);Mpz-Cre)were *** results show that a significant proportion of axons in the sciatic nerve of Ezh2-depleted mice remain *** highlights the crucial role of Ezh2 in initiating Schwann cell ***,we observed that 21 days after inducing a sciatic nerve crush injury in these mice,most axons had remyelinated at the injury site in the control nerve,while Ezh2^(fl/fl);Mpz-Cre mice had significantly fewer remyelinated axons compared with their wild-type *** suggests that the absence of Ezh2 in Schwann cells impairs myelin formation and *** conclusion,EZH2 has emerged as a pivotal regulatory factor in the process of demyelination and myelin regeneration following peripheral nerve *** EZH2 activity during these processes may offer a promising therapeutic target for the treatment of peripheral nerve injuries.

关键词： demyelination EZH2 myelination peripheral nerve injury PRC2 remyelination Schwann cells sciatic nerve crush sciatic nerve transection

Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future

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Neural Regeneration Research 2025年第4期20卷 946-959页

作者： Zhiyuan Yin Jiahui Kang xuan Cheng hui Gao Shujia Huo Haiwei xu Key Lab of Visual Damage and Regeneration&Restoration of Chongqing Southwest Eye HospitalSouthwest HospitalThird Military Medical University(Army Medical University)ChongqingChina

Müller glia,as prominent glial cells within the retina,plays a significant role in maintaining retinal homeostasis in both healthy and diseased *** lower vertebrates like zebrafish,these cells assume responsibility for spontaneous retinal regeneration,wherein endogenous Müller glia undergo proliferation,transform into Müller glia-derived progenitor cells,and subsequently regenerate the entire retina with restored ***,Müller glia in the mouse and human retina exhibit limited neural reprogramming.Müller glia reprogramming is thus a promising strategy for treating neurodegenerative ocular disorders.Müller glia reprogramming in mice has been accomplished with remarkable success,through various *** in molecular,genetic,epigenetic,morphological,and physiological evaluations have made it easier to document and investigate the Müller glia programming process in ***,there remain issues that hinder improving reprogramming efficiency and ***,understanding the reprogramming mechanism is crucial toward exploring factors that will improve Müller glia reprogramming efficiency,and for developing novel Müller glia reprogramming *** review describes recent progress in relatively successful Müller glia reprogramming *** also provides a basis for developing new Müller glia reprogramming strategies in mice,including epigenetic remodeling,metabolic modulation,immune regulation,chemical small-molecules regulation,extracellular matrix remodeling,and cell-cell fusion,to achieve Müller glia reprogramming in mice.

关键词： cell fusion chemical small-molecules epigenetic extracellular matrix immune metabolic mice Müller glia neurodegenerative diseases reprogramming retina regeneration

融合粗糙集和扩散二元萤火虫算法的属性约简方法

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系统工程与电子技术 2016年第10期38卷 2449-2456页

作者：程美英倪志伟朱旭辉合肥工业大学管理学院安徽合肥230009 过程优化与智能决策教育部重点实验室安徽合肥230009 新加坡南洋理工大学计算机科学与工程学院计算智能中心实验室新加坡639798

从一维细胞自动机模型入手,将自然界中种群的扩散行为引入二元萤火虫算法(binary glowworm swarm optimization,BGSO)中,提出了一种扩散二元萤火虫算法(spread binary glowworm swarm optimization,SBGSO)。该算法对萤火虫个体设置营养... 详细信息

从一维细胞自动机模型入手,将自然界中种群的扩散行为引入二元萤火虫算法(binary glowworm swarm optimization,BGSO)中,提出了一种扩散二元萤火虫算法(spread binary glowworm swarm optimization,SBGSO)。该算法对萤火虫个体设置营养值及营养阈值的上下限,然后执行扩散操作,以正态分布方式产生新的个体,并淘汰一些持续表现很差的个体,释放资源给其他个体,以保持种群的动态多样性。然后将SBGSO作为搜索策略,粗糙集(rough set,RS)作为评价准则,应用于大数据预处理的属性约简问题。为验证本文算法的可行性,采用5个UCI数据集进行实验,并结合10-fold和支持向量机(support vector machine,SVM)算法对预测结果分类准确率进行分析,通过与其他算法对比,表明本文算法具有较好的约简效果。

关键词：二元萤火虫算法扩散机制一维细胞自动机粗糙集属性约简

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论农地承包经营权流转过程中的法律关系

特区经济 2011年第3期 177-180页

作者：韦留柱张旭慧师景慧河南师范大学河南新乡453007

农地承包经营权流转方式的不同决定其法律关系存在差异性,本文结合课题小组对河南省广大农村的调查,主要从农地承包经营权转包、出租、互换、入股、转让、抵押的法律关系进行探讨分析,并基于流转中法律关系运行所引发的争议纠纷,从立法... 详细信息

农地承包经营权流转方式的不同决定其法律关系存在差异性,本文结合课题小组对河南省广大农村的调查,主要从农地承包经营权转包、出租、互换、入股、转让、抵押的法律关系进行探讨分析,并基于流转中法律关系运行所引发的争议纠纷,从立法、司法等角度提出合理的解决机制,以期对全国农村土地承包经营权流转的有序推进提供参考。

关键词：农地承包经营权流转法律关系

Improvement of Electrochemical Machining Accuracy by Using Dual Pole Tool

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厦门大学学报（自然科学版） 2002年第S1期41卷 118-页

作者： zhu Di, xu hui-yu (Department of Mechanical Engineering, Nanjing University of Aeronaut ics & Astronautics, Nanjing 210016, China)

Electrochemical machining (ECM) is one of the best al ternatives for producing complex shapes in advanced materials used in aircraft a nd aerospace industries. However, the reduction of the stray material removal co ntinues to be major challenges for industries in addressing accuracy improvement . This study presents a method of improving machining accuracy in ECM by using a dual pole tool with a metallic bush outside the insulated coating of a cathode tool. The bush is connected with anode and so the electric field at the side gap area is substantially weakened. The modeling and simulation indicate that the p ositive bush brings down the current density at the side gap area of the machine d hole and hence reduces the stray material removal there. It has been experimen tally observed that the machining accuracy and the process stability are signifi cantly improved.

关键词： electrochemical machining dual pole tool accura cy

Effects of Puerarin on Pulmonary Vascular Remodeling and Protein Kinase C-α in Chronic Cigarette Smoke Exposure Smoke-exposed Rats

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2008年第1期28卷 27-32页

作者：朱朝霞徐永健邹晖张珍祥倪望陈士新 Department of Respiratory Medicine Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

In order to investigate the effects of puerarin on pulmonary vascular remodeling and protein kinase C-α （PKC-α） in chronic exposure smoke rats, 54 male Wistar rats were randomly divided into 7 groups： control group （C group）, smoke exposure groups （S4w group, S8w group）, puerarin groups （P4w group, P8w group）, propylene glycol control groups （PC4w group, PC8w group）. Rats were exposed to cigarette smoke or air for 4 to 8 weeks. Rats in puerarin groups also received puerarin. To evaluate vascular remodeling, alpha-smooth muscle actin （α-SM-actin） staining was used to count the percentage of completely muscularised vessels to intraacinar pulmonary arteries （CMA/IAPA） which was determined by morphometric analysis of histological sections. Pulmonary artery smooth muscle cell （PASMC） apoptosis was detected by in situ end labeling technique （TUNEL）, and proliferation by proliferating cell nuclear antigen （PCNA） staining. Reverse transcription-polymerase chain reaction （RT-PCR）, immunofluorescence staining and Western blot analysis were done to detect the PKC-α mRNA and protein expression in pulmonary arteries. The results showed that in cigarette smoke-exposed rats the percentage of CMA/IAPA and α-SM-actin expression were increased greatly, PASMC apoptosis was increased and proliferation was markedly increased; Apoptosis indices （AI） and proliferation indices （PI） were higher than in C group; AI and PI were correlated with vascular remodeling indices; The expression of PKC-α mRNA and protein in pulmonary arteries was significantly higher than in C group. In rats treated with puerarin, the percentage of CMA/IAPA and cell proliferation was reduced, whereas PASMC apoptosis was increased; The expression levels of PKC-α mRNA and protein were lower than in smoke exposure rats. There was no difference among all these data between S groups and PC groups. These findings suggested that cigarette smoke-induced pulmonary vascular remodeling was most likely an effect of the imbalance

关键词： puerarin vessel remodeling cigarette smoke protein kinase C apoptosis proliferation