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激波管壁AlO自由基B^2Σ^+-X^2Σ^+和C^2Π_r-X^2Σ^+带系辐射光谱的研究

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光谱学与光谱分析 2010年第4期30卷 865-868页

作者：彭志敏杨乾锁刘春竺乃宜姜宗林中国科学院力学研究所高温气体动力学重点实验室北京100190

爆轰驱动过程中产生的高温高压气流对铝质膜片、激波管壁产生烧蚀和冲刷作用,以致激波管壁、端盖上附有氧化铝等杂质,而高温下AlO自由基在气体分子的高速碰撞下被激发并产生强烈的辐射,从而干扰了高温气体辐射光谱的分析。用爆轰驱动加... 详细信息

爆轰驱动过程中产生的高温高压气流对铝质膜片、激波管壁产生烧蚀和冲刷作用,以致激波管壁、端盖上附有氧化铝等杂质,而高温下AlO自由基在气体分子的高速碰撞下被激发并产生强烈的辐射,从而干扰了高温气体辐射光谱的分析。用爆轰驱动加热技术将空气加热到4 000~7 000 K,利用多通道光学分析仪对AlO自由基辐射光谱进行分析,实验发现在460~530 nm波长范围内有多支辐射非常强烈的AlO自由基B2Σ+-X2Σ+(T00=20 689 cm-1)带系辐射谱带,且每支谱带都由多个带头组成,带头间隔约为2 nm,带头处于高频位置并向低频方向伸延。通过实验与理论计算相结合,重点分析了AlO自由基B2Σ+-X2Σ+带系辐射光谱的结构特征。AlO自由基C2Πr-X2Σ+(T00=33 047 cm-1)带系辐射光谱处于270~335 nm波长范围内,其辐射强度相对于B2Σ+-X2Σ+带系较弱,并且与OH基A2Σ+-X2Π(T00=32 682 cm-1)带系辐射光谱互相干扰而难以分辨,对该波段高温空气的辐射光谱分析产生不利的影响。

关键词：激波管高温气体光学多通道分析仪分子光谱 AlO自由基

动态增强MRI评估胰腺导管内乳头状黏液性肿瘤恶性潜能的价值

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放射学实践 2019年第12期34卷 1370-1374页

作者：柴丽王晴柔朱乃懿王婷柴维敏上海交通大学医学院附属瑞金医院放射科 200025 上海交通大学医学院附属瑞金医院病理科 200025

目的:探讨采用动态增强MRI评估胰腺导管内乳头状黏液性肿瘤(IPMNs)恶性潜能的价值。方法:回顾性分析经手术病理证实115例IPMNs患者的动态增强MRI的影像学表现、临床及病理资料。男75例,女40例;年龄41~83岁,平均(63.8±7.9)岁。将患者分... 详细信息

目的:探讨采用动态增强MRI评估胰腺导管内乳头状黏液性肿瘤(IPMNs)恶性潜能的价值。方法:回顾性分析经手术病理证实115例IPMNs患者的动态增强MRI的影像学表现、临床及病理资料。男75例,女40例;年龄41~83岁,平均(63.8±7.9)岁。将患者分为轻度~中度不典型增生组、重度不典型增生组和IPMN伴浸润性癌三组。分析三组IPMNs在DCE-MRI动态增强MRI上的影像学表现,包括病灶位置、壁结节、主胰管管径、胰腺周围组织及血管侵犯情况等。参照2016年修订版福冈共识对IPMNs进行影像学分类。结果:三组间可强化壁结节≥5mm、主胰管≥10mm、主胰管改变伴远端实质萎缩这3个征象出现率的差异有统计学意义(P<0.05)。肿瘤指标CA19-9升高在低度~中度不典型增生与浸润性癌组间差异有统计学意义(P<0.017)。结论:DCE-MRI动态增强MRI对评估IPMNs恶性潜能有一定价值。

关键词：胰腺肿瘤导管内乳头状黏液性肿瘤磁共振成像对比增强扫描病理分级

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激波波后氮分子发射光谱的测量

流体力学实验与测量 2000年第3期14卷 57-60,65页

作者：杨乾锁余西龙姜乃波竺乃宜林贞彬中国科学院力学研究所高温气体动力学研究开放实验室北京100080

利用多通道光学分析仪测量激波波后不同时刻高温氮气的辐射光谱发现，辐射随时间发生强烈的变化。在非平衡态和平衡态，光谱的各条谱线强度有明显的差别。光谱的结构特征也依赖于激波的速度。

关键词：激波激波管激波速度氮分子辐射光谱

Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2982-2997页

作者： Hongli Li Jianhua Huang Di Zhao Lemei zhu Zheyu Zhang Min yi Weijun Peng Department of Integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina National Clinical Research Center for Metabolic Diseases ChangshaHunan ProvinceChina Hunan Academy of Chinese Medicine ChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina

Alzheimer’s disease not only affects the brain,but also induces metabolic dysfunction in peripheral organs and alters the gut *** aim of this study was to investigate systemic changes that occur in Alzheimer’s disease,in particular the association between changes in peripheral organ metabolism,changes in gut microbial composition,and Alzheimer’s disease *** do this,we analyzed peripheral organ metabolism and the gut microbiota in amyloid precursor protein-presenilin 1(APP/PS1)transgenic and control mice at 3,6,9,and 12 months of ***-month-old APP/PS1 mice exhibited cognitive impairment,Alzheimer’s disease-related brain changes,distinctive metabolic disturbances in peripheral organs and fecal samples(as detected by untargeted metabolomics sequencing),and substantial changes in gut microbial composition compared with younger APP/PS1 ***,a strong correlation emerged between the gut microbiota and kidney metabolism in APP/PS1 *** findings suggest that alterations in peripheral organ metabolism and the gut microbiota are closely related to Alzheimer’s disease development,indicating potential new directions for therapeutic strategies.

关键词： Alzheimer’s disease APP/PS1 mice brain-kidney axis gut microbiota heart-brain axis liver-brain axis lung-brain axis microbiota-gut-brain axis peripheral organ metabolism spleen-brain axis

Surface embedded binary Co-Cu hydroxy phosphate over surface of oxy/hydroxides for efficient nitrate reduction to ammonia

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Nano Research 2025年第1期18卷 195-207页

作者： Chun zhu yifei Yang yike Jing Zhen Zeng Xuesong yi Wei Sun Fei Yang Key Laboratory of Agro-Forestry Environmental Processes and Ecological Regulation of Hainan Province School of Environmental Science and EngineeringHainan UniversityHaikou 570228China

Electrochemical nitrate reduction reaction(NO3RR)to ammonia is a promising approach to address excess Ncontamination in aqueous environment but suffers from a limited ammonia yield and selectivity due to the low concentration and sluggish *** work reports a three-dimensional porous electrode with binary Co_(2)Cu_(1)hydroxy phosphate embedded into the surface of Ni_(3)Co_(1)oxy/hydroxides(CoCu-PH@NiCo/Ni,“PH”means phosphate-hydroxide),which delivers a yield of 4.13 mg·h^(-1)·cm^(-2)with a high Faraday efficiency of 92.6%under a low nitrate concentration of 40 mM and provide an impressive *** embedded structure of the as-prepared catalyst exhibits unique metal coordination ligands and valence states different from the unitary *** electrochemical in situ infrared spectra and theoretical calculations revealed that the Co sites with the ability to dissociate water molecular to form adsorbed OH*can effectively provide the required protons for the deoxygenation and hydrogenation steps during NO3-conversion,thereby,effectively reducing the energy barrier of the key transition states in the NO3RR process to improve the intrinsic *** demonstrate that the rational design of binary components with the appropriate ability to activate water molecules as well as the threedimensional porous skeletal structure are expected to promote effectively the low-concentration nitrates conversion to ammonia.

关键词： nitrate reduction hydroxy phosphate surface embedded water dissociation active hydroxy adsorbed

JF-10氢氧爆轰驱动激波风洞自由流的测量和诊断

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流体力学实验与测量 2000年第3期14卷 12-17页

作者：林贞彬郭大华竺乃宜葛学真余西龙杨乾锁姜乃波中国科学院力学研究所高温气体动力学研究开放实验室北京100080

针对JF-10氢氧爆轰驱动风洞运行的高焓高速状态，采用吸收光谱技术、皮托压力瞬态测量技术、电离探针等的测试方法，测量了自由流中一氧化氮的含量和离子浓度、皮托压力及其沿喷管出口半径方向的分布。并根据以上各项测量结果判断了自... 详细信息

针对JF-10氢氧爆轰驱动风洞运行的高焓高速状态，采用吸收光谱技术、皮托压力瞬态测量技术、电离探针等的测试方法，测量了自由流中一氧化氮的含量和离子浓度、皮托压力及其沿喷管出口半径方向的分布。并根据以上各项测量结果判断了自由流的非平衡程度。

关键词：氢氧爆双驱激波风洞离子浓度自由流

利用吸收光谱法测量激波风洞自由流中一氧化氮的含量

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流体力学实验与测量 1999年第4期13卷 62-66页

作者：余西龙杨乾锁姜乃波郭大华葛学真林贞彬竺乃宜中国科学院力学研究所高温气体动力学实验室北京100080

以空心阴极灯Te 灯作为光源,采用光学多道分析仪(OMA) ,首先在静态条件下,获得了Te 灯的透射光强随一氧化氮压强的变化曲线,计算出一氧化氮对Te 灯214nm 和225 .9nm 两条谱线的吸收系数。根据OMA 拍摄的氢氧爆轰驱动激波风洞喷管出口气... 详细信息

以空心阴极灯Te 灯作为光源,采用光学多道分析仪(OMA) ,首先在静态条件下,获得了Te 灯的透射光强随一氧化氮压强的变化曲线,计算出一氧化氮对Te 灯214nm 和225 .9nm 两条谱线的吸收系数。根据OMA 拍摄的氢氧爆轰驱动激波风洞喷管出口气流中一氧化氮γ带(A2 + →X2 ∏跃迁) 对Te 灯的吸收光谱。

关键词：激波风洞一氧化氮吸收光谱含量测量自由流

Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats

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World Journal of Gastroenterology 2025年第1期31卷 93-109页

作者： Ping Zhang ying zhu Pu Chen Tong Zhou Zhe-yi Han Jun Xiao Jian-Feng Ma Wen Ma Peng Zang ying Chen Graduate School Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina Key Laboratory of Aerospace Nutrition and Food Engineering China Astronaut Research and Training CenterBeijing 100094China Department of Gastroenterology The Air Force Medical CenterBeijing 100142China Department of Blood Transfusion Air Force Medical CenterBeijing 100142China

BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility *** pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal ***,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal *** cells are the pacemakers of gastrointestinal *** To investigate the effects of Bifidobacterium lactis(***)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit *** The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 *** tail group was given *** BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/***&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and *** fecal flora and mucosal flora of rats in each group were detected by 16S *** Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic *** microgravity reduced the expressions of SCF and c-kit,and increased the express

关键词： Simulated microgravity Rat Intestinal flora Gastrointestinal motility Stem cell factor/c-kit signaling pathway

Protein-based functional hydrogel improves cutaneous nerve repair and diabetic wound healing

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Nano Research 2025年第1期18卷 586-596页

作者： Hanzhi Lu Mingrui Cui yi Wang Xinran Du Xinyi Zhou Yuhan Fang Xiaoyan Gao ying Peng Jianyong zhu Guang Yang Fulun Li Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine College of Biological Science and Medical EngineeringDonghua UniversityShanghai 201620China Clinical Laboratory Medicine Center Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China

Cutaneous nerve regeneration in diabetic wounds remains a challenge for current clinical ***,a natural protein-based functional hydrogel is developed using keratin as the sole matrix,and protocatechuic aldehyde(PA)and zinc ions as the building blocks through dual-dynamic crosslinking reactions of thiol-aldehyde addition and catecholzinc ions *** unique structural design endows the hydrogel with excellent injectability,skin adhesion,self-healing and antibacterial ability,and *** addition,this hydrogel acts as a drug carrier for the loading and sustained release of phellopterin(PP),a natural compound extracted from traditional Chinese medicine Angelica *** findings demonstrate that the PP-loaded hydrogel promotes cutaneous nerve regeneration,angiogenesis and tissue remodeling in the full-thickness wounds in both db/db and streptozotocin-induced C57BL/6 diabetic mice,notably by the synergistic effect of zinc ions and PP,showing a great potential in diabetic wound therapy.

关键词： functional hydrogel cutaneous nerve regeneration dynamic crosslinking diabetic wounds