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Expert Consensus on the Treat-to-Target Strategy for Psoriasis With Biological Agents in China(Simplified Edition)

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International Journal of Dermatology and Venereology 2024年第2期7卷 61-69页

作者： Ai-jun Chen Da-Xing Cai Xiang Chen Yong Cui Yan ding Heng Gu Xing-Hua Gao Chao Ji Xiao-jing Kang Ye-Hong Kuang Cheng-Zhi Lyu Min Li Wei Li Xia Li Yu-Zhen Li Xiao-Yong Man Jian-jun Qiao Juan Su liang-Dan Sun Yu-Ling Shi Juan Tao Jian-Xin Xia Rong Xiao Bin Yang Wu zhu Xue-jun Zhang Committee on Psoriasis Dermatology and Venereology Branch of the Chinese Medical Association Department of Dermatology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Dermatology Qilu HospitalShandong UniversityJinanShandong 250100China Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunan 410008China Department of Dermatology China-Japan Friendship HospitalBeijing 100192China Department of Dermatology Hainan Provincial Hospital of Skin DiseaseHaikouHainan 570311China Department of Dermatology Hospital for Skin DiseasesChinese Academy of Medical SciencesNanjingJiangsu 210042China Department of Dermatology The First Hospital of China Medical UniversityShenyangLiaoning 110002China Department of Dermatology The First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian 350004China Department of Dermatology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqiXinjiang Uyghur Autonomous Region 830001China Department of Dermatology Dalian Dermatosis HospitalDalianLiaoning 116021China Department of Dermatology Dushu Lake Hospital Affiliated to Soochow UniversitySuzhouJiangsu 215127China Department of Dermatology West China Hospital of Sichuan UniversityChengduSichuan 610044China Department of Dermatology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Dermatology The Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150086China Department of Dermatology The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiang 310003China Department of Dermatology The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiang 310003China Department of Dermatology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230022China Department of Dermatology Shanghai Skin Disease HospitalTongji University School of MedicineShanghai 200093China Department of Dermatology The Union Hospital of Tongji Medical CollegeHuazhong University of Science and Te

Psoriasis is a chronic,recurrent,inflammatory systemic disease that is not only characterized by skin manifestations but may also be accompanied by various comorbidities,imposing a heavy burden on patients’physical and mental health and affecting their quality of *** the continuous approval of various biological agents for clinical use has provided more effective treatment options to patients with psoriasis,no consensus on the evaluation of comprehensive treatment goals has yet been *** treat-to-target(T2T)strategy requires consideration of multiple dimensions of treatment outcomes,the development of long-term management goals,and regular assessments of treatment conditions,which are often used in the management of chronic ***,based on the latest consensuses and guidelines,research data,and clinical experience as well as the combination of survey results and expert group discussions,the present consensus focuses on 4 dimensions of short-and long-term integrated management goals for biological agents:alleviating skin lesions,improving quality of life,screening and managing psoriasis comorbidities,and ensuring drug *** implementation methods,evaluation time,treatment monitoring,and program adjustments are also herein described to achieve comprehensive management of psoriasis to the maximum *** consensus provides a reference for clinical practice.

关键词： psoriasis biological agents treat-to-target comorbidity consensus

Stepped-up development of accelerator mass spectrometry method for the detection of ^(60)Fe with the HI-13 tandem accelerator

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Nuclear Science and Techniques 2024年第4期35卷 136-143页

作者： Yang Zhang Sheng-Quan Yan Ming He Qing-Zhang Zhao Wen-Hui Zhang Chao-Xin Kan Jian-Ming Zhou Kang-Ning Li Xiao-Fei Wang Jian-Cheng Liu Zhao-Hua Peng zhuo liang Ai-Ling Li Jian Zheng Qi-Wen Fan Yun-Ju Li You-Bao Wang Zhi-Hong Li Yang-Ping Shen ding Nan Wei Nan Yu-Qiang Zhang Jia-Ying-Hao Li jun-Wen Tian Jiang-Lin Hou Chang-Xin Guo Zhi-Cheng Zhang Ming-Hao zhu Yu-Wen Chen Yu-Chen Jiang Tao Tian Jin-Long Ma Yi-Hui Liu jing-Yu Dong Run-Long Liu Mei-Yue-Nan Ma Yong-Shou Chen Wei-Ping Liu Bing Guo China Institute of Atomic Energy P.O.Box 275(10)Beijing 102413China College of Science Southern University of Science and TechnologyShenzhen 518055China School of Physics Xi’an Jiaotong UniversityXi’an 710049China

The Moon provides a unique environment for investigating nearby astrophysical events such as *** samples retain valuable information from these events,via detectable long-lived“fingerprint”radionuclides such as^(60)*** this work,we stepped up the development of an accelerator mass spectrometry(AMS)method for detecting^(60)Fe using the HI-13tandem accelerator at the China Institute of Atomic Energy(CIAE).Since interferences could not be sufficiently removed solely with the existing magnetic systems of the tandem accelerator and the following Q3D magnetic spectrograph,a Wien filter with a maximum voltage of±60 kV and a maximum magnetic field of 0.3 T was installed after the accelerator magnetic systems to lower the detection background for the low abundance nuclide^(60)Fe.A 1μm thick Si_(3)N_(4) foil was installed in front of the Q3D as an energy *** particle detection,a multi-anode gas ionization chamber was mounted at the center of the focal plane of the ***,an^(60)Fe sample with an abundance of 1.125×10^(-10)was used to test the new AMS *** results indicate that^(60)Fe can be clearly distinguished from the isobar^(60)*** sensitivity was assessed to be better than 4.3×10^(-14)based on blank sample measurements lasting 5.8 h,and the sensitivity could,in principle,be expected to be approximately 2.5×10^(-15)when the data were accumulated for 100 h,which is feasible for future lunar sample measurements because the main contaminants were sufficiently separated.

关键词： Accelerator mass spectrometry Wien filter Isobar separation Supernovae Chang'e-5 lunar samples

Hif-1α/Hsf1/Hsp70 signaling pathway regulates redox homeostasis and apoptosis in large yellow croaker(Larimichthys crocea)under environmental hypoxia

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Zoological Research 2021年第6期42卷 746-760页

作者： Sheng-Yu Luo jing-Qian Wang Cheng Liu Xin-Ming Gao Yi-Bo Zhang Jie ding Cong-Cong Hou jun-Quan zhu Bao Lou Wei-liang Shen Xiong-Fei Wu Chun-Dan Zhang Dao-jun Tang Key Laboratory of Applied Marine Biotechnology by the Ministry of Education School of Marine SciencesNingbo UniversityNingboZhejiang 315211China Zhejiang Academy of Agricultural Sciences HangzhouZhejiang 310021China State Key Laboratory of Large Yellow Croaker Breeding Ningbo Academy of Oceanology and FisheryNingboZhejiang 315012China

Oxygen is an essential molecule for animal respiration,growth,and *** in terrestrial environments,contamination and climate change have led to the frequent occurrence of hypoxia in aquatic environments,thus impacting aquatic animal ***,the adaptative mechanisms underlying fish responses to environmental hypoxia remain largely ***,we used large yellow croaker(Larimichthys crocea)and large yellow croaker fry(LYCF)cells to investigate the roles of the Hif-1α/Hsf1/Hsp70 signaling pathway in the regulation of cellular redox homeostasis,and *** confirmed that hypoxia induced the expression of Hif-1α,Hsf1,and Hsp70 in vivo and in *** Hsp70 knockdown/overexpression indicated that Hsp70 was required for maintaining redox homeostasis and resisting oxidative stress in LYCF cells under hypoxic ***70 inhibited caspase-dependent intrinsic apoptosis by maintaining normal mitochondrial membrane potential,enhancing Bcl-2 mRNA and protein expression,inhibiting Bax and caspase3 mRNA expression,and suppressing caspase-3 and caspase-9 ***70 suppressed caspaseindependent intrinsic apoptosis by inhibiting nuclear translocation of apoptosis-inducing factor(AIF)and disturbed extrinsic apoptosis by inactivating *** knockdown/overexpression of Hif-1αand dual-luciferase reporter assay indicated that Hif-1αactivated the Hsf1 DNA promoter and enhanced Hsf1 mRNA ***1 enhanced Hsp70 mRNA transcription in a similar *** summary,the Hif-1α/Hsf1/Hsp70 signaling pathway plays an important role in regulating redox homeostasis and anti-apoptosis in *** under hypoxic stress.

关键词： Hypoxia Larimichthys crocea Apoptosis Redox homeostasis Hif-1α/Hsf1/Hsp70

Scavenging reactive oxygen species is a potential strategy to protect Larimichthys crocea against environmental hypoxia by mitigating oxidative stress

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Zoological Research 2021年第5期42卷 592-605页

作者： Sheng-Yu Luo Cheng Liu Jie ding Xin-Ming Gao jing-Qian Wang Yi-Bo Zhang Chen Du Cong-Cong Hou jun-Quan zhu Bao Lou Xiong-Fei Wu Wei-liang Shen Key Laboratory of Applied Marine Biotechnology by the Ministry of Education School of Marine SciencesNingbo UniversityNingboZhejiang 315211China Zhejiang Academy of Agricultural Sciences HangzhouZhejiang 310021China State Key Laboratory of Large Yellow Croaker Breeding Ningbo Academy of Oceanology and FisheryNingboZhejiang 315012China

The large yellow croaker(Larimichthys crocea),which is an economically important mariculture fish in China,is often exposed to environmental *** oxygen species(ROS)homeostasis is essential for the maintenance of normal physiological conditions in an *** evidence that environmental hypoxia leads to ROS overproduction is scarce in marine ***,the sources of ROS overproduction in marine fish under hypoxic stress are poorly *** this study,we investigated the effects of hypoxia on redox homeostasis in *** and the impact of impaired redox homeostasis on *** first confirmed that hypoxia drove ROS production mainly via the mitochondrial electron transport chain and NADPH oxidase complex pathways in *** and its cell line(large yellow croaker fry(LYCF)cells).We subsequently detected a marked increase in the antioxidant systems of the ***,imbalance between the pro-oxidation and antioxidation systems ultimately led to excessive ROS and oxidative *** viability showed a remarkable decrease while oxidative indicators,such as malondialdehyde,proteincarbonylation,and8-hydroxy-2 deoxyguanosine,showed a significant increase after hypoxia,accompanied by tissue ***(NAC)reduced ROS levels,alleviated oxidative damage,and improved cell viability in *** uptake of ROS scavengers(e.g.,NAC and elamipretide Szeto-Schiller-31)and inhibitors(e.g.,apocynin,diphenylene iodonium,and 5-hydroxydecanoate)may be effective at overcoming hypoxic *** findings highlight previously unstudied strategies of hypoxic toxicity resistance in marine fish.

关键词： Dissolvedoxygen Redox homeostasis Antioxidant system Nacetylcysteine

Positioning taxonomic research for the future

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Zoological Systematics 2022年第3期47卷 185-187页

作者： Deyuan Hong Wenying zhuang Min zhu Keping Ma Xiaoquan Wang Dawei Huang Yalin Zhang Guodong Ren Wenjun Bu Wanzhi Cai Dong Ren ding Yang Aiping liang Fengyan Bai Runzhi Zhang Fumin Lei Shuqiang Li Hongzhi Kong Lei Cai Yucheng Dai Chaodong zhu Qisen Yang jun Chen Zhongli Sha Jianping Jiang jing Che Donghui Wu Jiatang Li Qiang Wang Xinli Wei Ming Bai Xingyue Liu Xuexin Chen Gexia Qiao State Key Laboratory of Systematic and Evolutionary Botany Institute of BotanyChinese Academy of SciencesBeijing 100093China State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China College of Life Sciences Nankai UniversityTianjin 300071China College of Plant Protection Northwest A&F UniversityYanglin 712100China School of Life Sciences Hebei UniversityBaoding 071002China College of Plant Protection China Agricultural UniversityBeijing 10084China Key Lab of Insect Evolution and Environmental Change College of Life SciencesCapital Normal UniversityBeijing 100048China School of Life Sciences Tianjin Normal UniversityTianjin 300387China Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China School of Ecology and Nature Conservation Beijing Forestry UniversityBeijing 10083China Institute of Oceanology Chinese Academy of SciencesQingdao 266071China Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan Province Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610041China State Key Laboratory of Genetic Resources and Evolution and Yunnan Laboratory of Molecular Biology of Domestic AnimalsKunming Institute of ZoologyChinese Academy of SciencesKunming 650223China Key Lab of Wetland Ecology and Environment Northeast Institute of Geography and AgroecologyChinese Academy of SciencesChangchun 130102China Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province Institute of Insect SciencesZhejiang UniversityHangzhou 310058

Why do taxonomists matter? The work of taxonomists is often understated if not completely misunderstood. Without taxonomists, organisms cannot be accurately identified, neither can these organisms be given universally accepted names, and reliably positioned in the phylogenetic tree of life. Thanks to the work of taxonomists over the last 269 years since Carl Linnaeus established the binomial system, we can now measure the health and wealth of our biodiversity in a refined, science-based inventory prescribed by stringent nomenclatural rules.

关键词： stated prescribed refined

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Biomarkers of aging

Science China(Life Sciences) 2023年第5期66卷 893-1066页

作者： Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie ding junlin Feng jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying jing dingfeng Li Jiaming Li jingyi Li Qinhao liang Rui liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar junhong Luo Jianwei Lv jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang zhuo Zhang Min Zhou Rui Zhou Qingchen zhu Zhengmao zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen jun Chen Weimin Ci Bi-Sen ding Qiurong ding Feng Gao jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao jing Nie Yaojin Peng jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu jing Ye Rui Yue Cuntai Zhang Hongbo Zhang liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai zhu Weiguo Zou Gang Pei Guang-Hui Liu Aging Biomarker Consortium(ABC) Beijing 100101China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijing 100101China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Department of Dermatology Xiangya HospitalCentral South UniversityChangsha 410008China Hunan Key Laboratory of Aging Biology Xiangya HospitalCentral South UniversityChangsha 410008China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008China Clinic Center of Human Gene Research Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Hubei Clinical Research Center of Metabolic and Cardiovascular Disease Huazhong University of Science and TechnologyWuhan 430022China Hubei Key Laboratory of Metabolic Abnormalities and Vascular Aging Huazhong University of Science and TechnologyWuhan 430022China Stem Cell Translational Research Center Tongji HospitalTongji University School of MedicineShanghai 200065China Department of Nuclear Medicine Daping HospitalThird Military Medical UniversityChongqing 400042China CAS Key Laboratory of Nutrition Metabolism and Food SafetyShanghai Institute of Nutrition and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Shanghai Key Laboratory of Maternal Fetal Medicine Clinical and Translational Research Center of Shanghai First Maternity and Infant HospitalFrontier Science Center for Stem Cell ResearchShanghai Key Laboratory of Signaling and Disease ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China The Department of Endovascular Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Key Laboratory of Regenerative Medicine of Ministry of Education Institute of Ageing and Regenerative MedicineJ

Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological *** a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly *** immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this ***,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory *** fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant.

关键词： aging senescence biomarker clock

Endothelial Nitric Oxide Synthase Gene Polymorphisms Associated with Susceptibility to High Altitude Pulmonary Edema in Chinese Railway Construction Workers at Qinghai-Tibet over 4500 Meters above Sea Level

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Chinese Medical Sciences Journal 2010年第4期25卷 215-221页

作者： Yu-jing Sun Ming-wu Fang Wen-quan Niu Guang-ping Li jing-liang Liu Shou-quan ding Ying Xu Guo-shu Yu Jian-qun Dong Yun-jun Pan Guang-xue Yu Hui-cheng Sun Zhong-hou Jia jun Liu Xiao-ming Wang Qin Si Qi-xia Wu Wen-yu Zhou Tong-chun zhu Chang-chun Qiu National Laboratory of Medical Molecular Biology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100005 China Hospital of China Railway Construction Corporation Beijing 100039 China

Objective To examine whether the polymorphisms of endothelial nitric oxide synthase (eNOS) gene are associated with the susceptibility to high altitude pulmonary edema (HAPE) in Chinese railway construction workers at Qinghai-Tibet where the altitude is over 4 500 m above sea level. Methods A case-control study was conducted including 149 HAPE patients in the construction workers and 160 healthy controls randomly recruited from their co-workers, matching the patients in ethnicity, age, sex, lifestyle, and working conditions. Three polymorphisms of eNOS gene, T-786C in promoter, 894G/T in exon 7, and 27bp variable number tandem repeat (VNTR) in intron 4, were genotyped using polymerase chain reaction (PCR) and confirmed with DNA sequencing. Results The frequencies of 894T allele and heterozygous G/T of the 894G/T variant were significantly higher in HAPE patients group than in the control group (P=0.0028 and P=0.0047, respectively). However, the frequencies of the T-786C in promoter and the 27bp VNTR in intron 4 were not significantly different between the two groups. Haplotypic analysis revealed that the frequencies of two haplotypes (H3,T-T-b, b indicates 5 repeats of 27 bp VNTR; H6, C-G-a, a indicates 4 repeats of 27 bp VNTR) were significantly higher in HAPE patients (both P<0.0001). On the contrary, the frequencies of H1 (T-G-b) and H2 (T-G-a) were lower in HAPE patients than in healthy controls (both P<0.001). Conclusions Two haplotypes (T-T-b and C-G-a) may be strongly associated with susceptibility to HAPE. Compared with the individual alleles of eNOS gene, the interaction of multiple genetic markers within a haplotype may be a major determinant for the susceptibility to HAPE.

关键词：基因多态性建筑工人肺水肿中国铁路一氧化氮合成酶易感性高原铁路建设

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基于近红外技术的火药安定期评价新方法

兵工学报 2018年第3期39卷 463-467页

作者：周静丁黎张俊林安静祝艳龙梁忆西安近代化学研究所陕西西安710065

为解决现存火药安定性评价方法安全性差、操作繁琐、耗时等问题,提出一种火药安定期评价新方法。采用热加速老化方法获取不同安定剂含量的实验试样,开展火药老化的动力学方程研究。借助近红外技术与化学计量学方法建立了安定剂含量的近... 详细信息

为解决现存火药安定性评价方法安全性差、操作繁琐、耗时等问题,提出一种火药安定期评价新方法。采用热加速老化方法获取不同安定剂含量的实验试样,开展火药老化的动力学方程研究。借助近红外技术与化学计量学方法建立了安定剂含量的近红外定量模型,经过对模型的分析和优化得到安定剂含量的最佳定量模型。实例应用结果表明:该模型的决定系数R2为0.999 6,预测最大误差低于0.04%,证明了该模型具有高度可行性,可实现火药安定期的无损、快速、实时评估。

关键词：火药安定期安定剂近红外技术评价

秦皇岛海域秋季石花菜(Gelidium amansii)附生大型海藻的实验分类学研究

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海洋与湖沼 2023年第2期54卷 493-501页

作者：张瑶闫璟黄冰心郭优璇梁俊霞王雪聪闫盼竹丁兰平天津师范大学生命科学学院天津动植物抗性重点实验室天津300387

秦皇岛海域属于我国渤海区域典型的大型海藻分布区,该海区资源丰富,在我国大型海藻区系中占有较为重要的位置。于2021年秋季在该海域采集石花菜(Gelidium amansii)样品进行活体培养,对其藻体附生的其他季节大型海藻的状况加以观察研究... 详细信息

秦皇岛海域属于我国渤海区域典型的大型海藻分布区,该海区资源丰富,在我国大型海藻区系中占有较为重要的位置。于2021年秋季在该海域采集石花菜(Gelidium amansii)样品进行活体培养,对其藻体附生的其他季节大型海藻的状况加以观察研究。通过实验生物学方法对石花菜附生藻生殖特征和生态习性进行了观察,结合附生藻形态特征进行物种分类鉴定。经过培养与鉴定,确定该水域石花菜的附生大型海藻共有7种,其中红藻4种,即丛出旋体藻(Audouinelladaviesii)、旋体藻(Auduinella sp.)、茎丝藻小枝变型(Stylonema alsidii f. ramosum)和日本新管藻(Neosiphonia japonica);绿藻2种,即苍白刚毛藻(Cladophora albida)和浒苔[Enteromorpha (Ulva) prolifera];蓝藻1种,即丝状鞘丝藻(Lyngbya confervoides);丛出旋体藻、茎丝藻小枝变型和苍白刚毛藻为河北海域的新记录物种。研究结果表明,室内人工培养可作为个体微小的附生大型海藻分类鉴定的有效补充方法,也能为分子鉴定提供纯净的样品来源,同时也可为研究附生藻的季节变化以及分析生物地理学分布提供重要依据。

关键词：秦皇岛秋季石花菜(Gelidium amansii) 附生藻培养实验分类学形态学