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chinese Science Bulletin 1999年第S2期44卷 166-168页

作者： zhu bingquan, dong yunpeng, {2. xiangyang and zhang zhengwei guangzhou institute of Geochemistry, chinese academy of sciences, guangzhou 510640, china guangzhou institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China

THE parallel strike of geochemical steep zones and geophysical gradient zones represent geochemicalboundaries with tectonic hiding and almost no magmatism, but there existed great variation of lithosphereor crustal thickness. Tectonically, these areas were located in the foreland basins of craton margin. Thesegeochemical boundaries were usually associated with the low-temperature mineralization and petroleumgeneration. The Nd, Sr and Pb isotopic evidence indicated that there still existed strong crustal-mantle interaction through fluid activation along deep-seated faults at the craton margin. Fig. 1 is the 2.7Pb/2.4 Pb-2.8Pb/2.4 Pb diagram, which shows the evident crust-mantle mixing for crude oil, chloroform bitumen-A,

关键词： low temperature mineralization domain geochemical steep zones geophysical gradient zones.

Features of inclusions in the Funiushan gold deposits of Central china and its implications for prospecting

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chinese Science Bulletin 1999年第S2期44卷 15-16页

作者： zhang zhengwei~1, {2.~1 and DENG Jun~2.1. guangzhou institute of Geochemistry, chinese academy of sciences, guangzhou 510640, china 2. china University of Geoscience, Beijing 100083, china guangzhou institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China china University of Geoscience Beijing 100083 China

GOLD mineralization popularly occurs in Funiushan area. Based on the studies on more than 40 gold deposits or ore spots, it is shown that most of them are small in scale except the Pengou gold deposit, whichcan be developed into a medium one. The Pengou is a gold deposit of medium-low temperature hydrothermal type. 1 Geological setting The Funiushan gold mineralization zone lying in the contiguous region of Nanzhao, Fangcheng andLushan Counties, Henan Province, is stituated on the tectonic and geochemical boundary between theNorth china block and Qinling Orogenic belt, and transverses the two first-grade tectonic units. Thehost rocks are mainly the strata of Xionger group （Pt2./sub> ） and the Funiushan granitic batholith. The Penggougold deposit is just located on the large-scale fault of Xiatang-Guihe. A series of metamorphic rocks ofXionger Group outcroped in the north of the deposit. 2.The features of deposit The ore bodies mostly appear in thick plate with sag-and-swell variation. The gold-bearing alterationzone from upper to lower layers can be divided as granite→ pyritization and phyllic alteration→ alteredgranitic porphyry→quartz vein→pyritization and phyllic alteration→cataclastic granite with phyllic alteration, i. e. the upper and lower gold-bearing layers can be separated by the altered granite. The ore

关键词： gold deposit inclusion geochemistry Funiushan.

Relation of Isotope Geochemical Steep Zones with Geophysical Fields and Tectonics in the Junction Area of the Cathaysian,Yangtze and Indochina Plates

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Acta Geologica Sinica(English Edition) 2000年第2期74卷 236-240页

作者： zhu bingquan dong {2. chang xiangyang zhang zhengwei guangzhou institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640Guangdong

Through lead isotope geochemical mapping in the Yunnan-Guizhou area geochemical steep zones (GSZ) have been established, which clearly reveal the junction relationship of the Cathaysian, Yangtze and Indo-china plates. GSZ are closey related to gravity Moho gradient zones and lithospheric thickness. The GSZ between the Yangtze and Cathaysian plates is consistent with the Shizong-Mile tectonic belt, where island are basalts are well developed. The Yangtze-Indo-china GSZ is parallel to the Jing{2.-Mojiang volcanic belt in rift-island are environments. The evidence of geology, geophysics and geochemistry all indicates that Cathaysia was subducted towards the Yangtze plate and that the Yangtze plate was underthrust beneath the Indo-china, which took place from the Early Carboniferous to the Early Triassic.

关键词： junction relationship of the Cathaysia Yangtze and Indo-china plates geochemical steep zone gradient zone of gravity Moho

Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite

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Science china(Physics,Mechanics & Astronomy) 2020年第4期63卷 2-19页

作者： Shuang-Nan zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge Yudong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li zhengwei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang xiangyang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei zhang ChunLei zhang ChengMo zhang Fan zhang HongMei zhang Juan zhang Qiang zhang ShenYi zhangs Shu zhang Tong zhang Wanchang zhang Wei zhang WenZhao zhang Yi zhang YiFei zhang YongJie zhang Yue zhang Zhao zhang Zhi zhang ZiLiang zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan zhu Yue zhu RenLin zhuang Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of chinese academy of sciences Beijing 100049China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China

As china’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2.17, is a wide-band(1-2.0 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2.3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be *** we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results.

关键词： X-and γ-ray telescopes and instrumentation neutron stars black holes X-ray binaries γ-ray bursts

Insight-HXMT observations of the first binary neutron star merger GW170817

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Science china(Physics,Mechanics & Astronomy) 2018年第3期61卷 26-33页

作者： TiPei Li ShaoLin Xiong ShuangNan zhang FangJun Lu LiMing Song XueLei Cao Zhi chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge Yudong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li zhengwei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang xiangyang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei zhang ChunLei zhang ChengMo zhang Fan zhang HongMei zhang Juan zhang Qiang zhang Shu zhang Tong zhang Wei zhang Wanchang zhang WenZhao zhang Yi zhang Yue zhang YiFei zhang YongJie zhang Zhao zhang ZiLiang zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue zhu YuXuan zhu changLin Zou Key Laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China Department of Physics Tsinghua University Beijing 100084 China University of chinese academy of sciences Chinese Academy of Sciences Beijing 100049 China Department of Astronomy Beijing Normal University Beijing 100088 China Department of Engineering Physics Tsinghua University Beijing 100084 China

Finding the electromagnetic （EM） counterpart of binary compact star merger, especially the binary neutron star （BNS） merger, is critically important for gravitational wave （GW） astronomy, cosmology and fundamental physics. On Aug. 17, 2.17, Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart, GRB 170817A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope （HE） onboard Insight-HXMT （Hard X-ray Modulation Telescope） is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart （SSS17a/AT2.17gfo） with very large collection area （M000 cm2. and microsecond time resolution in 0.2.5 MeV. In addition, Insight-HXMT quickly implemented a Target of Opportunity （TOO） observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy （0.2.5 MeV） radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817A. Meanwhile, Insight-HXMT/HE provides one of the most stringent constraints （-10-7 to 104 erg/cm2.s） for both GRB170817A and any other possible precursor or extended emissions in 0.2.5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event.

关键词： GW170817 BNS merger gravitational wave electromagnetic counterpart

Overexpression of Sirt6 ameliorates sleep deprivation induced-cognitive impairment by modulating glutamatergic neuron function

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Neural Regeneration Research 2023年第11期18卷 2449-2458页

作者： Jinpiao zhu chang Chen Zhen Li Xiao{2. Liu Jingang He Ziyue Zhao Mengying He Binbin Nie Zili Liu Yingying Chen Kuanpin Su Xiang Li Juxiang Chen Hongbing Xiang Fuqiang Xu Kangguang Lin Zongze zhang Jie Wang Department of Anesthesiology Brain Research CenterDepartment of NeurosurgeryZhongnan HospitalWuhan UniversityWuhanHubei ProvinceChina Department of Anesthesiology and Pain Medicine Tongji Hospital of Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Anesthesia and Intensive Care Peter Hung Pain Research InstituteThe Chinese University of Hong KongHong Kong Special Administration RegionChina Key Laboratory of Magnetic Resonance in Biological Systems State Key Laboratory of Magnetic Resonance and Atomic and Molecular PhysicsNational Center for Magnetic Resonance in WuhanWuhan Institute of Physics and MathematicsInnovation Academy for Precision Measurement Science and TechnologyChinese Academy of Sciences-Wuhan National Laboratory for OptoelectronicsWuhanHubei ProvinceChina Key Laboratory of Nuclear Radiation and Nuclear Energy Technology Institute of High Energy PhysicsChinese Academy of SciencesBeijingChina The Brain Cognition and Brain Disease institute(BCBDI) NMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal ProductsShenzhen Key Laboratory of Viral Vectors for BiomedicineShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research InstitutionsShenzhenGuangdong ProvinceChina Mind-Body Interface Research Center(MBI-Lab) China Medical University HospitalTaichungTaiwanChina An-Nan Hospital China Medical UniversityTainanTaiwanChina Department of Neurosurgery Changhai HospitalNaval Medical UniversityShanghaiChina Department of Affective Disorders The Affiliated Brain Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina institute of Neuroscience and Brain Diseases Xiangyang Central HospitalAffiliated Hospital of Hubei University of Arts and ScienceXiangyangHubei ProvinceChina University of chinese academy of sciences BeijingChina

Sleep benefits the restoration of energy metabolism and thereby suppo rts neuronal plasticity and cognitive ***6 is a NAD+-dependent protein deacetylase that has been recognized as an essential regulator of energy metabolism because it modulates various transcriptional regulators and metabolic *** aim of this study was to investigate the influence of Sirt6 on cerebral function after chronic sleep deprivation(CSD).We assigned C57BL/6J mice to control or two CSD groups and subjected them to AAV2.9-CMV-EGFP or AAV2.9-CMV-Sirt6-EGFP infection in the prelimbic cortex(PrL).We then assessed cerebral functional connectivity(FC) using resting-state functional MRI,neuron/astrocyte metabolism using a metabolic kinetics analysis;dendritic spine densities using sparse-labeling;and miniature excitato ry postsynaptic currents(mEPSCs) and action potential(AP) firing rates using whole-cell patchclamp *** addition,we evaluated cognition via a comprehensive set of behavioral *** with controls,Sirt6 was significantly decreased(P2.13C] acetate showed that CSD reduced neuronal Glu4and GABA2.ynthesis,which could be fully restored via forced Sirt6 ***,Sirt6 ove rexpression reversed CSD-induced decreases in AP firing rates as well as the frequency and amplitude of mEPSCs in PrL pyramidal *** data indicate that Sirt6 can improve cognitive impairment after CSD by regulating the PrL-associated FC network,neuronal glucose metabolism,and glutamatergic ***,Sirt6 activation may have potential as a novel strategy for treating sleep disorder-related diseases.

关键词： chronic sleep deprivation cognitive impairment functional connectivity glutamatergic neurons metabolic kinetics neuronal-astrocytic glucose metabolism prelimbic cortex REM sleep Sirt6 synaptic function

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Biomarkers of aging

Science china(Life sciences) 2023年第5期66卷 893-1066页

作者： Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le zhang Weiwei zhang Wenwan zhang Xing zhang zhuo zhang Min Zhou Rui Zhou Qingchen zhu Zhengmao zhu Feng Cao Zhongwei Cao Piu Chan chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai zhang Hongbo zhang Liang zhang Weiqi zhang Yong zhang Yun-Wu zhang zhuohua zhang Tongbiao Zhao Yuzheng Zhao Dahai zhu Weiguo Zou Gang Pei Guang-Hui Liu Aging Biomarker Consortium(ABC) Beijing 100101China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijing 100101China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Department of Dermatology Xiangya HospitalCentral South UniversityChangsha 410008China Hunan Key Laboratory of Aging Biology Xiangya HospitalCentral South UniversityChangsha 410008China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008China Clinic Center of Human Gene Research Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Hubei Clinical Research Center of Metabolic and Cardiovascular Disease Huazhong University of Science and TechnologyWuhan 430022China Hubei Key Laboratory of Metabolic Abnormalities and Vascular Aging Huazhong University of Science and TechnologyWuhan 430022China Stem Cell Translational Research Center Tongji HospitalTongji University School of MedicineShanghai 200065China Department of Nuclear Medicine Daping HospitalThird Military Medical UniversityChongqing 400042China CAS Key Laboratory of Nutrition Metabolism and Food SafetyShanghai Institute of Nutrition and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Shanghai Key Laboratory of Maternal Fetal Medicine Clinical and Translational Research Center of Shanghai First Maternity and Infant HospitalFrontier Science Center for Stem Cell ResearchShanghai Key Laboratory of Signaling and Disease ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China The Department of Endovascular Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Key Laboratory of Regenerative Medicine of Ministry of Education Institute of Ageing and Regenerative MedicineJ

Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological *** a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly *** immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this ***,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory *** fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant.

关键词： aging senescence biomarker clock

Efficacy,safety and pharmacokinetics of Unecritinib(TQ-B3101)for patients with ROS1 positive advanced non-small cell lung cancer:a Phase I/II Trial

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Signal Transduction and Targeted Therapy 2023年第7期8卷 3536-3546页

作者： Shun Lu Hongming Pan Lin Wu Yu Yao Jianxing He Yan Wang Xiuwen Wang Yong Fang Zhen Zhou Xicheng Wang Xiuyu Cai Yan Yu Zhiyong Ma Xuhong Min Zhixiong Yang Lejie Cao Huaping Yang Yongqian Shu Wu zhuang Shundong Cang Jian Fang Kai Li zhuang Yu Jiuwei Cui Yang zhang Man Li Xinxuan Wen Jie zhang Weidong Li Jianhua Shi Xingxiang Xu Diansheng Zhong Tao Wang Jiajia zhu Department of Medical Oncology Shanghai Chest HospitalSchool of MedicineShanghai Jiao Tong University200030 ShanghaiChina Department of Medical Oncology Sir Run Run Shaw HospitalZhejiang University310016 HangzhouChina Department of Thoracic Medical Oncology The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South University(Hunan Cancer Hospital)410031 ChangshaChina Department of Medical Oncology The First Affiliated Hospital of Xi’an Jiaotong University710061 XianChina Department of Thoracic Surgery The First Affiliated Hospital of Guangzhou Medical University510120 GuangzhouChina Department of Medical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College100021 BeijingChina Department of Oncology Qilu Hospital of Shandong University250012 JinanChina Department of Oncology The First Affiliated Hospital/School of Clinical Medicine of Guangdong Pharmaceutical University510699 GuangzhouChina Department of Medical Oncology Sun Yat-sen University Cancer Center510060 GuangzhouChina Department of Respiratory Medicine Harbin Medical University Cancer Hospital150081 HarbinChina Department of Medical Oncology Henan Tumor Hospital450003 ZhengzhouChina Department of Oncology Radiotherapy Anhui Chest Hospital230022 HefeiChina Department of Cancer Center Affiliated Hospital of Guangdong Medical University524000 ZhanjiangChina Department of Respiratory Medicine The First Affiliated Hospital of the University of Science and Technology of ChinaAnhui Provincial Hospital230031 HefeiChina Department of Respiratory and Critical Care Medicine Xiangya Hospital Central South University410008 ChangshaChina Department of Cancer Center Jiangsu Province Hospital210029 NanjingChina Department of Thoracic Oncology Fujian Cancer Hospital and Fujian Medical University Cancer Hospital350014 FuzhouChina Department of Medical Oncology Henan Province People’s Hospital450003 ZhengzhouCh

This phase I/II trial characterized the tolerability,safety,and antitumor activities of unecritinib,a novel derivative of crizotinib and a multi-tyrosine kinase inhibitor targeting ROS1,ALK,and c-MET,in advanced tumors and ROS1 inhibitor-naive advanced or metastatic non-small cell lung cancer(NSCLC)harboring ROS1 *** patients received unecritinib 100,2.0.

关键词： patients lung cancer

广东云开山国家级自然保护区鸟兽红外相机调查初报

维普期刊数据库评论

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生物多样性 2020年第9期28卷 1154-1159页

作者：李林妙池辉云万雅琼周佳滨张礼标何向阳黄文忠张伯军徐湛荣刘昌传赖任燕朱秀芳李友余李佳琦陈金平广东省科学院动物研究所/广东省动物保护与资源利用重点实验室/广东省野生动物保护与利用公共实验室广州510260 广东云开山省级自然保护区管理处广东茂名525300 生态环境部南京环境科学研究所南京210042

2.17年1月至2.19年9月,我们在广东云开山国家级自然保护区3个观测样区布设61台红外相机,对兽类和鸟类多样性进行调查。共记录到野生兽类4目7科9种,鸟类6目14科34种,其中广东省新记录1种,为蓝绿鹊(Cissa chinensis),记录国家II级重点保... 详细信息

2.17年1月至2.19年9月,我们在广东云开山国家级自然保护区3个观测样区布设61台红外相机,对兽类和鸟类多样性进行调查。共记录到野生兽类4目7科9种,鸟类6目14科34种,其中广东省新记录1种,为蓝绿鹊(Cissa chinensis),记录国家II级重点保护动物3种,为原鸡(Gallus gallus)、白鹇(Lophura nycthemera)和蓝绿鹊。相对多度较高的5种兽类依次为赤腹松鼠(Callosciurus erythraeus)、赤麂(Muntiacus vaginalis)、鼬獾(Melogale moschata)、野猪(Sus scrofa)和果子狸(Paguma larvata),相对多度较高的3种鸟类分别是紫啸鸫(Myiophoneus caeruleus)、虎斑地鸫(Zoothera dauma)和红嘴相思鸟(Leiothrix lutea)。通过对相对多度指数前三的鸟兽日活动节律观察分析,共发现4种典型昼行性动物(赤腹松鼠、紫啸鸫、虎斑地鸫和红嘴相思鸟)和1种典型夜行性动物(鼬獾)。赤麂日活动呈现两个高峰时段,分别为12.00–14:00和18:00–2.:00。本研究评估了广东云开山国家级自然保护区部分兽类和鸟类资源现状,为保护区野生动物保护与管理提供了数据支持。

关键词：兽类鸟类物种多样性红外相机监测云开山国家级自然保护区

原发性慢性失眠患者失眠严重程度与抑郁和焦虑的相关性研究

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健康体检与管理 2023年第3期4卷 264-269页

作者：高向阳李霞徐三平贺明霞张淑珍辛杰王倩梁丽华李慧包春华李彦刘娜朱元芳王莉晴曾强中国人民解放军总医院第二医学中心健康管理研究院北京100853 邯郸市中心医院健康管理中心河北邯郸056000 武汉协和医院健康管理中心湖北武汉430022 郑州颐和医院健康管理中心河南郑州450018 渭南市第二医院健康管理中心陕西渭南714099 宝鸡高新医院健康管理中心陕西宝鸡721013 西安交通大学第二附属医院健康管理中心陕西西安710004 辽宁电力中心医院健康管理中心辽宁沈阳110403 湖南省人民医院健康管理中心湖南长沙410021 瑞安市人民医院健康管理中心浙江温州325207 重庆大学附属三峡医院健康管理中心重庆404031 广州市干部疗养院广东广州510970 自贡市第四人民医院健康管理中心四川自贡643099 广安市人民医院健康管理中心四川广安638099

目的:分析原发性慢性失眠患者中抑郁及焦虑对失眠严重程度的影响。方法:方法:本研究为横断面调查,在全国13个城市招募有失眠症状的18~65岁成年人,对其中诊断为原发性慢性失眠的患者,通过问卷获取年龄、性别等信息;以及抑郁自评量表(SDS... 详细信息

目的:分析原发性慢性失眠患者中抑郁及焦虑对失眠严重程度的影响。方法:方法:本研究为横断面调查,在全国13个城市招募有失眠症状的18~65岁成年人,对其中诊断为原发性慢性失眠的患者,通过问卷获取年龄、性别等信息;以及抑郁自评量表(SDS)、焦虑自评量表(SAS)和匹兹堡睡眠质量指数问卷(PSQI)得到SDS得分、SAS得分、PSQI得分等指标;根据PSQI评分将患者的慢性失眠分成轻度失眠、中度失眠、重度失眠3个等级,通过有序多分类Logistic回归,分析焦虑和抑郁对原发性慢性失眠严重程度的影响。结果:结果:本研究在有失眠症状的4189例个体中,筛选出符合纳入排除标准的研究对象595例,其中,轻度失眠者2.7例(39.80%)、中度失眠者32.例(54.10%)、重度失眠者36例(6.1%)。有序多分类Logistic回归分析发现,抑郁及焦虑程度对失眠严重程度具有统计学意义,而病程、年龄、性别、合并慢性病、婚姻状况、经济水平和职业状况均无统计学意义。原发性慢性失眠患者的SDS得分每增加1分,其“失眠严重程度增加”的OR值为原来的1.041倍[95%CI(1.017~1.064)];原发性慢性失眠患者的SAS得分每增加1分,其“失眠严重程度增加”的OR值为原来的1.051倍[95%CI(1.02.~1.077)]。结论:结论:焦虑和抑郁是原发性慢性失眠患者失眠严重程度的独立影响因素;抑郁或焦虑越严重,失眠程度也越重。

关键词：慢性失眠匹兹堡睡眠质量指数抑郁自评量表焦虑自评量表抑郁焦虑