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Chinese Optics Letters 2018年第8期16卷 75-79页

作者： Zhaohui Peng Chunxia aia Yuqing Zhang zhonghua zhu Xiaojuan Liu Institute of Modern Physics and Department of Physics Hunan University of Science and Technology Xiangtan ~111201 China Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control of Ministry of Education Department of Physics Hunan Normal University Changsha 410081 China

We propose a feasible scheme of generating multipartite entanglement with the dipole induced transparency （D/T） effect in indirectly coupled dipole-microcavity systems. It is shown that the transmission spectrum is closely related with the interference of dipole-microcavity systems, and we can generate different classes of multi- partite entanglement, e.g., the Greenberger-Horne-Zeilinger state, the W state, and the Dicke state, of the di- pole emitters just by choosing an appropriate frequency of the incident photon. Benefiting from the DIT effect, the schemes may work in the bad or low-Q cavity regime only if the large Purcell factor of the dipole-microcavity system is fulfilled, and they are also insensitive to experimental noise, which may be feasible with present acces- sible technology.

关键词： Multipartite entanglement generation with dipole induced transparency effect in indirectly coupled dipole-microcavity systems DIT QED

Stability and variability of molecular subtypes: comparative analysis of primary and metastatic triple-negative breast cancer

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Cancer Biology & Medicine 2024年第9期21卷 784-798页

作者： Xiuzhi zhu Xiaohan Ying Yin Liu Yunyi Wang Li Chen Zhiming Shao Xi Jin Yizhou Jiang zhonghua Wang Key Laboratory of Breast Cancer in Shanghai Shanghai Institute of Infectious Disease and Biosecurity Department of Oncology Shanghai Medical College Fudan University Department of Breast Surgery Fudan University Shanghai Cancer Center

Objective: Triple-negative breast cancer(TNBC) is a heterogeneous and aggressive cancer. Although our previous study classified primary TNBC into four subtypes, comprehensive longitudinal investigations are ***: We assembled a large-scale, real-world cohort comprised of 880 TNBC patients [465 early-stage TNBC(e TNBC) and 415 metastatic TNBC(m TNBC) patients] who were treated at Fudan University Shanghai Cancer Center. The longitudinal dynamics of TNBC subtypes during disease progression were elucidated in this patient cohort. Comprehensive analysis was performed to compare primary and metastatic lesions within specific TNBC ***: The recurrence and metastasis rates within 3 years after initial diagnosis in the e TNBC cohort were 10.1%(47/465). The median overall survival(OS) in the m TNBC cohort was 27.2 months [95% confidence interval(CI), 24.4±30.2 months], which indicated a poor prognosis. The prognostic significance of the original molecular subtypes in both e TNBC and m TNBC patients was confirmed. Consistent molecular subtypes were maintained in 77.5% of the patients throughout disease progression with the mesenchymal-like(MES) subtype demonstrating a tendency for subtype transition and brain metastasis. Additionally, a precision treatment strategy based on the metastatic MES subtype of target lesions resulted in improved progression-free survival in the FUTURE ***: Our longitudinal study comprehensively revealed the clinical characteristics and survival of patients with the original TNBC subtypes and validated the consistency of most molecular subtypes throughout disease progression. However, we emphasize the major importance of repeat pathologic confirmation of the MES subtype.

关键词： Triple-negative breast cancer metastasis molecular subtype overall survival primary tumor

Polysaccharides of Aspergillus cristatus attenuate obesity by regulating gut microbiota and gut microbiota-related metabolites

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Food Science and Human Wellness 2024年第3期13卷 1513-1530页

作者： Mingzhi zhu Bohao Shang Fang Zhou Yong Yuan Feiyan Yin Jin Cao Jianan Huang Kunbo Wang Xin Zeng Maiquan Li zhonghua Liu College of Horticulture Hunan Agricultural UniversityChangsha 410128China College of Life Sciences Huaibei Normal UniversityHuaibei 235000China Hunan Tea Group Co. Ltd.Changsha 410128China School of Food Science and Technology Hunan Agricultural UniversityChangsha 410128China

Golden-flower fungus,the only dominant microorganism determining the Fu-brick tea quality through fermentation and the important microbe in Liupao tea,is considered a potential probiotic fungus based on its anti-obesity ***,the classification of golden-flower fungi is still controversial;the anti-obesity effect of golden-flower fungus polysaccharides remains *** this study,we identify a golden-flower strain as Aspergillus cristatus based on morphological characteristics and multigene phylogeny analysis,which resolves the controversy of ***,we find *** polysaccharides(ACPS)attenuate obesity in *** modulate gut bacterial *** which Akkermansia,Akkermansia muciniphila,Bacteroides,Romboutsia,Blautia,and Desulfovibrio are considered the core microbes regulated by *** increase fecal total short-chain fatty acid content and serum,hepatic,and fecal total bile acid ***,ACPS-induced gut microbiota alteration plays a causal role in the protection from obesity,according to a fecal transplantation ***,ACPS ameliorate obesity by regulating gut microbiota and gut microbiota-related metabolites.

关键词： Golden-flower fungus Aspergillus cristatus Polysaccharides Obesity Gut microbiota

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关于新建本科院校发展定位的研究

高教探索 2004年第4期 37-39,42页

作者：朱中华淮阴工学院高等教育研究所

文章论述了新建本科院校发展定位的意义，分析了定位的基本内容，指出了定位应遵循的基本原则。

关键词：新建本科院校发展定位文章基本原则基本内容意义

理想性与现实性的统一:马克思恩格斯“无产阶级政党”概念探析

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思想教育研究 2022年第9期 67-74页

作者：石德金朱中华中山大学马克思主义学院广东广州510275

在马克思和恩格斯的理论中,无产阶级政党既有共产主义理想的应然维度,又有现实工人运动的实然维度。然而,正是对这种理想性与现实性之间张力的误解,西方学界产生了关于“无产阶级政党”概念截然相反的两种理解,割裂了这一概念的整体性... 详细信息

在马克思和恩格斯的理论中,无产阶级政党既有共产主义理想的应然维度,又有现实工人运动的实然维度。然而,正是对这种理想性与现实性之间张力的误解,西方学界产生了关于“无产阶级政党”概念截然相反的两种理解,割裂了这一概念的整体性。这两种看似截然相反的理解,实质上都割裂了理想性与现实性之间的内在统一,否认了无产阶级政党实现其理想的现实可能性。因此,有必要回到马克思和恩格斯的经典文本,重新厘清“无产阶级政党”概念理想性与现实性之间的关系,还原这一概念的本真,这无疑对新时代加强党的建设具有重要启发意义。

关键词：无产阶级政党马克思恩格斯共产主义理想现实运动

Significant genomic introgression from grey junglefowl(Gallus sonneratii)to domestic chickens(Gallus gallus domesticus)

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1482-1493页

作者： Xiurong Zhao Junhui Wen Xinye Zhang Jinxin Zhang Tao zhu Huie Wang Weifang Yang Guomin Cao Wenjie Xiong Yong Liu Changqing Qu zhonghua Ning Lujiang Qu National Engineering Laboratory for Animal Breeding College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin Xinjiang Production and Construction CorpsTarim UniversityAlar 843300China Beijing Municipal General Station of Animal Science Beijing 100107China Animal husbandry station of Fangchenggang FangchenggangGuangxi Province 538001China Animal Disease Prevention and Control Center of Fangchenggang FangchenggangGuangxi Province 538001China Beijing Agricultural Effect Poultry Industry Co. Ltd.Beijing 101100China Engineering Technology Research Center of Anti‑aging Chinese Herbal Medicine of Anhui Province Fuyang Normal UniversityFuyangAnhui 236037China

Background Chicken is one of the most numerous and widely distributed species around the world,and many studies support the multiple ancestral origins of domestic *** research regarding the yellow skin phenotype in domestic chickens(regulated by BCO2)likely originating from the grey junglefowl serves as crucial evidence for demonstrating the multiple origins of ***,beyond the BCO2 gene region,much remains unknown about the introgression from the grey junglefowl into domestic ***,in this study,based on wholegenome data of 149 samples including 4 species of wild junglefowls and 13 local domestic chicken breeds,we explored the introgression events from the grey junglefowl to domestic *** We successfully detected introgression regions besides BCO2,including two associated with growth trait(IGFBP2 and TKT),one associated with angiogenesis(TIMP3)and two members of the heat shock protein family(HSPB2 and CRYAB).Our findings suggest that the introgression from the grey junglefowl may impact the growth performance of ***,we revealed introgression events from grey junglefowl at the BCO2 region in multiple domestic chicken breeds,indicating a phenomenon where the yellow skin phenotype likely underwent strong selection and was ***,our haplotype analysis shed light on BCO2 introgression event from different sources of grey junglefowl into domestic chickens,possibly suggesting multiple genetic flows between the grey junglefowl and domestic *** In summary,our findings provide evidences of the grey junglefowl contributing to the genetic diversity of domestic chickens,laying the foundation for a deeper understanding of the genetic composition within domestic chickens,and offering new perspectives on the impact of introgression on domestic chickens.

关键词： BCO2 Domestic chickens Grey junglefowl Introgression

约4900年前东亚和东南亚枢纽地区狩猎采集向农业的转变

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Science Bulletin 2024年第1期69卷 103-113页

作者：马敏敏卢敏霞孙瑞朱忠华 Dorian Q.Fuller 郭健新何光林杨晓敏谭玲玲芦永秀董佳佳刘睿良杨继帅李波郭天南李小瑞赵东月张颖王传超董广辉 Key Laboratory of Western China’s Environmental Systems(Ministry of Education) College of Earth and Environmental SciencesLanzhou UniversityLanzhou 730000China Zhaotong University Zhaotong 657000China Westlake Laboratory of Life Sciences and Biomedicine Key Laboratory of Structural Biology of Zhejiang ProvinceSchool of Life SciencesWestlake UniversityHangzhou 310024China Institute of Basic Medical Sciences Westlake Institute for Advanced StudyHangzhou 310024China Yunnan Provincial Institute of Cultural Relics and Archaeology Kunming 650118China Institute of Archaeology University College LondonLondon WC1H 0PYUK School of Cultural Heritage Northwest UniversityXi’an 710069China State Key Laboratory of Cellular Stress Biology School of Life SciencesXiamen UniversityXiamen 361102China Department of Anthropology and Ethnology Institute of AnthropologySchool of Sociology and AnthropologyXiamen UniversityXiamen 361005China State Key Laboratory of Marine Environmental Science Xiamen UniversityXiamen 361102China Westlake Omics(Hangzhou)Biotechnology Co. Ltd.Hangzhou 310024China The Department of Asia British MuseumLondon WC1E 7JWUK Tonghai Cultural Relics Management Yuxi 652700China Group of Alpine Paleoecology and Human Adaptation Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China State Key Laboratory of Tibetan Plateau Earth System Resources and EnvironmentBeijing 100101China Ministry of Education Key Laboratory of Contemporary Anthropology Department of Anthropology and Human GeneticsSchool of Life SciencesFudan UniversityShanghai 200433China

The southward expansion of East Asian farmers profoundly influenced the social evolution of Southeast Asia by introducing cereal ***,the timing and routes of cereal expansion in key regions are unclear due to limited empirical *** we report macrofossil,microfossil,multiple isotopic(C/N/Sr/O)and paleoproteomic data directly from radiocarbon-dated human samples,which were unearthed from a site in Xingyi in central Yunnan and which date between 7000 and 3300 a *** isotopes reveal the earliest arrival of millet ca.4900 a BP,and greater reliance on plant and animal agriculture was indicated between 3800 and 3300 a *** dietary differences between hunter-gatherer and agricultural groups are also evident in the metabolic and immune system proteins analysed from their skeletal *** results of paleoproteomic analysis indicate that humans had divergent biological adaptations,with and without *** combined application of isotopes,archaeobotanical data and proteomics provides a new approach to documenting dietary and health changes across major subsistence transitions.

关键词： Isotopes Proteomics Yunnan Millet Agricultural origins Human health

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应用系统纺纱工艺降低成纱条干CV值

棉纺织技术 2006年第6期34卷 43-45页

作者：朱忠华恒生纺织实业发展(安徽)有限公司

为了降低成纱条干CV,在纺纱各工序应用了系统纺纱工艺原理。认为原料是纺纱质量的前提,设备服从于工艺,工艺服从于质量。在开清棉工序要精细抓棉,以梳代打;在梳棉工序要合理配置梳棉工艺;精梳工序采用后退式给棉;并条工序要合理配置并... 详细信息

为了降低成纱条干CV,在纺纱各工序应用了系统纺纱工艺原理。认为原料是纺纱质量的前提,设备服从于工艺,工艺服从于质量。在开清棉工序要精细抓棉,以梳代打;在梳棉工序要合理配置梳棉工艺;精梳工序采用后退式给棉;并条工序要合理配置并合和牵伸;粗纱工序要控制张力;细纱工序要控制牵伸区纤维的运动并确定适当的牵伸倍数。从而使改前改后的条干CV普遍降低1个百分点以上。

关键词：条干CV 精细抓棉固定盖板并合牵伸粗纱张力纤维运动

潜伏背斜精细建模及其应用效果分析——以川东石炭系气田为例

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天然气勘探与开发 2024年第3期47卷 32-45页

作者：梁顺军徐敏郭海洋陆林超王征李金枝赵振伟朱中华游李伟王兰英中国石油集团东方地球物理勘探公司西南物探分公司四川成都610213 中国石油集团东方地球物理勘探公司西南物探研究院四川成都610213 中国石油西南油气田公司开发事业部四川成都610051

四川盆地川东高陡构造带油气勘探对象主要以背斜圈闭为主,因大多数地面背斜出露石灰岩,保存条件差,天然气勘探价值不高,而潜伏背斜保存条件良好,成为天然气聚集的有利场所。川东地区石炭系气藏是构造圈闭型,落实圈闭形态十分重要,直接... 详细信息

四川盆地川东高陡构造带油气勘探对象主要以背斜圈闭为主,因大多数地面背斜出露石灰岩,保存条件差,天然气勘探价值不高,而潜伏背斜保存条件良好,成为天然气聚集的有利场所。川东地区石炭系气藏是构造圈闭型,落实圈闭形态十分重要,直接关系钻探获气成功率。目前,石炭系潜伏背斜天然气勘探开发已进行到深入挖潜阶段,但仍有一些潜伏背斜地震成果不落实,井—震深度误差大,值得人们深入研究。依据地震剖面、地面地质、钻测井资料,建立精细潜伏背斜模式,划分为4大类、7亚类及30个小型,并对4大类潜伏背斜勘探开发效果进行总体评价。基于新建潜伏背斜模式,在3方面得到应用:①基于潜伏背斜模式,进行模型正演和反演,有利于分析复杂波长、时间域构造畸变现象及高点偏移规律;②有利于建立合理的时深转换及叠前深偏速度模型,提高深度域构造形态的可靠性;③基于潜伏背斜模式的水平叠加时间剖面(简称叠加剖面)基本反射特征,从而判定陡潜背斜的基本类型和形态,避免深度域里造成“假潜伏背斜”。川东地区新的潜伏背斜精细建模,将在石炭系气藏深入挖潜中进一步发挥积极作用。

关键词：石炭纪潜伏背斜精细建模地震成果精度分析

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一种基于矿体轮廓线的三维建模新方法

武汉大学学报（信息科学版） 2016年第10期41卷 1359-1365页

作者：毕林刘晓明陈鑫朱忠华中南大学资源与安全工程学院湖南长沙410083 长沙迪迈信息科技有限公司湖南长沙410083

结合轮廓线拼接法和体数据等值面法提出了一种新的矿体三维建模方法。该方法将轮廓线空间几何数据通过距离函数转换为距离场,从而将轮廓线间的表面重建问题转化为体数据等值面构造问题,避免了由人工指定轮廓线的对应关系;其次,通过扫描... 详细信息

结合轮廓线拼接法和体数据等值面法提出了一种新的矿体三维建模方法。该方法将轮廓线空间几何数据通过距离函数转换为距离场,从而将轮廓线间的表面重建问题转化为体数据等值面构造问题,避免了由人工指定轮廓线的对应关系;其次,通过扫描方式进行非欧氏距离变换实现距离场的计算及采用分治法层层建模,有效降低算法的时间和空间复杂度;然后,将非平直四棱柱作为体数据构造单元,以适应矿山实际数据的特殊性。实验证明该方法能够实现基于矿体轮廓线的复杂矿体三维自动建模,结果准确,模型质量高。

关键词：矿体三维建模距离场矿体轮廓线体数据等值面法