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奥沙利铂与伊立替康联合卡培他滨治疗结直肠癌伴肝转移的临床价值比较

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当代医学 2024年第11期30卷 64-67页

作者：张林锋周志明罗景方抚州市第一人民医院肿瘤内科江西抚州344000 抚州市中心血站江西抚州344000

目的比较奥沙利铂与伊立替康联合卡培他滨治疗结直肠癌伴肝转移的临床价值。方法选取2020年1月至2022年4月抚州市第一人民医院收治的70例结直肠癌患者作为研究对象,采用随机数字表法分为对照组与观察组,每组35例。对照组给予奥沙利铂联... 详细信息

目的比较奥沙利铂与伊立替康联合卡培他滨治疗结直肠癌伴肝转移的临床价值。方法选取2020年1月至2022年4月抚州市第一人民医院收治的70例结直肠癌患者作为研究对象,采用随机数字表法分为对照组与观察组,每组35例。对照组给予奥沙利铂联合卡培他滨治疗,观察组给予伊立替康联合卡培他滨治疗。比较两组临床疗效[总缓解率(OR)、疾病控制率(DCR)]、治疗前后免疫功能(CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+))、肿瘤标志物[血清癌胚抗原(CEA)、糖类抗原19-9(CA19-9)、糖类抗原125(CA125)]水平及不良反应发生情况。结果观察组OR、DCR均高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组CD4^(+)、CD4^(+)/CD8^(+)水平均高于对照组,而CD8^(+)水平低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组血清CEA、CA19-9、CA125水平均低于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论奥沙利铂与伊立替康联合卡培他滨治疗结直肠癌伴肝转移均具有较高的临床价值,但伊立替康联合卡培他滨的临床疗效更佳,可有效改善机体免疫功能,从而控制病情进展,促进患者康复,且具有较高安全性。

关键词：结直肠癌肝转移奥沙利铂伊立替康卡培他滨免疫功能肿瘤标志物

多弧离子镀CrAlSiN涂层对Cr12MoV钢显微硬度和耐磨性影响的研究

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热加工工艺 2024年第8期53卷 151-154页

作者：汪学静周志明袁林曾潇陈曦李成信曾华成重庆理工大学材料科学与工程学院重庆400054 重庆合创纳米科技有限公司重庆400054 重庆长安工业(集团)有限责任公司重庆401120

为了提高Cr12MoV表面的硬度和耐磨性能,采用多弧离子镀技术在淬火及氮化处理后的Cr12MoV冷作模具钢表面制备CrAlSiN涂层。结果表明:经淬火、氮化和镀膜处理后Cr12MoV钢的显微硬度得到提高,淬火后镀膜的硬度为3028 HV,氮化后镀膜的硬度为... 详细信息

为了提高Cr12MoV表面的硬度和耐磨性能,采用多弧离子镀技术在淬火及氮化处理后的Cr12MoV冷作模具钢表面制备CrAlSiN涂层。结果表明:经淬火、氮化和镀膜处理后Cr12MoV钢的显微硬度得到提高,淬火后镀膜的硬度为3028 HV,氮化后镀膜的硬度为3471 HV,是基体硬度(283HV)的12倍以上。氮化处理后镀膜层的摩擦系数低于淬火后镀膜层的摩擦系数。综合对比各试样的硬度、耐磨性、摩擦系数可知,多弧离子镀CrAlSiN涂层前氮化处理的效果优于淬火处理的。

关键词：多弧离子镀 CrAlSiN涂层 Cr12MoV钢淬火氮化

利用补偿电路设计并制作热敏电阻温度计——温度计设计的一种新思路

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物理通报 2024年第9期 96-100页

作者：姜涛周志明于华民孙艳空军航空大学航空基础学院吉林长春130012

利用NTC型热敏电阻,采用补偿法思想(补偿电路)设计了热敏电阻温度计,并进行测温验证了设计效果.补偿法设计温度计是一种完全区别于电桥法的温度计设计新思路,原理简单,实验设备要求低,可设计性强,特别适合于开发成新的设计性实验.

关键词：补偿法热敏电阻温度计设计性实验

辨证行为疗法对心脏移植术后精神障碍患者认知情绪、心理弹性水平及免疫功能状态的影响分析

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哈尔滨医药 2024年第4期44卷 91-94页

作者：张一杰周志明夏宁何岩郑州市第七人民医院心外科

目的研究辨证行为疗法对心脏移植术后精神障碍患者认知情绪、心理弹性水平及免疫功能状态的影响。方法选取87例心脏移植术后精神障碍患者随机分组，对照组43例给予常规干预，观察组44例增加辨证行为疗法，2周后，对比两组患者认知情... 详细信息

目的研究辨证行为疗法对心脏移植术后精神障碍患者认知情绪、心理弹性水平及免疫功能状态的影响。方法选取87例心脏移植术后精神障碍患者随机分组，对照组43例给予常规干预，观察组44例增加辨证行为疗法，2周后，对比两组患者认知情绪、心理弹性水平、免疫功能状态、生活质量。结果观察组干预后，消极情绪调节策略评分低于对照组，积极情绪调节策略评分高于对照组（P<0.05）；观察组干预后，心理弹性量表（CD-RISC）评分高于对照组（P<0.05）；观察组干预后，T淋巴细胞亚群（CD）CD4+、CD8+、CD4+/CD8+水平均高于对照组，CD8+水平低于对照组（P<0.05）；观察组干预后，认知功能、心理功能、躯体功能评分均高于对照组（P<0.05）。结论辨证行为疗法能够有效改善心脏移植术后精神障碍患者认知情绪和心理弹性水平，有利于增强免疫功能，提高生活质量。

关键词：心脏移植辨证行为疗法精神障碍认知情绪免疫功能

Mapping Network-Coordinated Stacked Gated Recurrent Units for Turbulence Prediction

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1331-1341页

作者： zhiming Zhang Shangce Gao MengChu zhou Mengtao Yan Shuyang Cao Faculty of Engineering University of ToyamaToyama 930-8555Japan Helen and John C.Hartmann Department of Electrical and Computer Engineering New Jersey Institute of TechnologyNewark NJ 07102 USA Gaoling School of Artificial Intelligence Renmin University of ChinaBeijing 100872China College of Civil Engineering Tongji UniversityShanghai 200092China IEEE

Accurately predicting fluid forces acting on the sur-face of a structure is crucial in engineering ***,this task becomes particularly challenging in turbulent flow,due to the complex and irregular changes in the flow *** this study,we propose a novel deep learning method,named mapping net-work-coordinated stacked gated recurrent units(MSU),for pre-dicting pressure on a circular cylinder from velocity ***-cally,our coordinated learning strategy is designed to extract the most critical velocity point for prediction,a process that has not been explored *** our experiments,MSU extracts one point from a velocity field containing 121 points and utilizes this point to accurately predict 100 pressure points on the *** method significantly reduces the workload of data measure-ment in practical engineering *** experimental results demonstrate that MSU predictions are highly similar to the real turbulent data in both spatio-temporal and individual ***,the comparison results show that MSU predicts more precise results,even outperforming models that use all velocity field *** with state-of-the-art methods,MSU has an average improvement of more than 45%in various indicators such as root mean square error(RMSE).Through comprehensive and authoritative physical verification,we estab-lished that MSU’s prediction results closely align with pressure field data obtained in real turbulence *** confirmation underscores the considerable potential of MSU for practical applications in real engineering *** code is available at https://***/zhangzm0128/MSU.

关键词： Convolutional neural network deep learning recurrent neural network turbulence prediction wind load predic-tion.

A STAR TRACKER FOR SPACE SHUTTLE

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Chinese Journal of Aeronautics 1989年第3期 182-191页

作者： zhou zhiming and Shen Gongxun Beijing University of Aeronautics and Astronautics

In this paper, equations are derived for the attitude stabilization of a spaceshuttle with a new type of sensor-charge coupled device （CCD） used in thestar tracker. A prototype of the star tracker is also described.

关键词： CCD Star A STAR TRACKER FOR SPACE SHUTTLE STAR

Electrocatalytic reduction of NO to NH_(3) in ionic liquids by P-doped TiO_(2) nanotubes

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Frontiers of Chemical Science and Engineering 2023年第6期17卷 726-734页

作者： Shangcong Zhang Qian Liu Xinyue Tang zhiming zhou Tieyan Fan Yingmin You Qingcheng Zhang Shusheng Zhang Jun Luo Xijun Liu College of Electrical and Electronic Engineering Wenzhou UniversityWenzhou 325035China Low Voltage Apparatus Technology Research Centre of Zhejiang Wenzhou UniversityWenzhou 325035China Institute for Advanced Study Chengdu UniversityChengdu 610106China College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou 325035China College of Chemistry Zhengzhou UniversityZhengzhou 450000China Tianjin Key Lab for Photoelectric Materials&Devices School of Materials Science and EngineeringTianjin University of TechnologyTianjin 300384China State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Compesite Structures School of ResourceEnvironments and MaterialsGuangxi UniversityNanning 530004China

Designing advanced and cost-effective electrocatalytic system for nitric oxide(NO)reduction reaction(NORR)is vital for sustainable NH_(3) production and NO removal,yet it is a challenging ***,it is shown that phosphorus(P)-doped titania(TiO_(2))nanotubes can be adopted as highly efficient catalyst for *** catalyst demonstrates impressive performance in ionic liquid(IL)-based electrolyte with a remarkable high Faradaic efficiency of 89%and NH3 yield rate of 425μg·h^(−1)·mg_(cat).^(−1),being close to the best-reported ***,the obtained performance metrics are significantly larger than those for N_(2) reduction *** also shows good durability with negligible activity decay even after 10 *** simulations reveal that the introduction of P dopants tunes the electronic structure of Ti active sites,thereby enhancing the NO adsorption and facilitating the desorption of ^(*)NH_(3).Moreover,the utilization of IL further suppresses the competitive hydrogen evolution *** study highlights the advantage of the catalyst−electrolyte engineering strategy for producing NH_(3) at a high efficiency and rate.

关键词： nitric oxide reduction reaction electrcatalysis ammonia production phosphorus-doped titania

Deformation mechanism of fine structure and its quantitative relationship with quasi-static mechanical properties in near β-type Ti-4.5Mo-5.1Al-1.8Zr-1.1Sn-2.5Cr-2.9Zn alloy

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Progress in Natural Science:Materials International 2021年第5期31卷 742-748页

作者： Xinjie Zhu Qunbo Fan Duoduo Wang Haichao Gong Yu Gao Hong Yu Xingwang Cheng zhiming zhou Liu Yang National Key Laboratory of Science and Technology on Materials Under Shock and Impact School of Materials Science and Engineering Beijing Institute of Technology Beijing Institute of Technology Chongqing Innovation Center School of Materials Science and Engineering Chongqing University of Technology Chengdu Advanced Metal Materials Industrial Technology Research Institute Co.Ltd.

The deformation mechanism of the fine structure composed of primary α phase(αp) and acicular secondary αphase(αs) on quasi-static mechanical properties is still not very clear. The main controversy is focused on the role of αpin the mechanical behavior. In this paper, the microstructure of the heat-treated near β-type Ti-4.5 Mo-5.1 Al-1.8 Zr-1.1 Sn-2.5 Cr-2.9 Zn alloy after tensile tests was observed by transmission electron microscopy(TEM). And the results showed that in the slight deformation region the dislocations were accumulated at the intersection ofαpand β matrix separated by αs, while only a few dislocations nucleated in β matrix. In the severe deformation region, a large quantity of dislocations in both αpand β matrix were observed. It can be inferred that αpdeformed firstly and then activated the deformation of β matrix, that is, the thickness of αpand the inter-particle spacing ofαsplayed a dominant role in the deformation process. The quantitative relationship between the yield strength and the microstructure parameters is consistent with this inference. By adjusting the solution treatment parameters and the subsequent aging treatment, three fine structures were obtained, and the corresponding mechanical properties were determined. Furthermore, the yield strength can be described by the mathematical model σy= 756.4 + 135.6/hp1/2+32.2/ds1/2, where hpand dsare the thickness of αpand the inter-particle spacing of αs,respectively.

关键词： Deformation mechanism Fine structure Quantitative relationship Titanium alloy

酸角壳基活性炭的制备及其吸附与电化学性能研究

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贵州师范大学学报（自然科学版） 2024年第1期42卷 119-126页

作者：曾艳萍杨菊芳揭楚玉周志明李旭张春浩黄齐林玉溪师范学院化学生物与环境学院云南玉溪653100 云南滇清环境科技有限公司云南玉溪653100 云南警官学院云南省刑事科学技术重点实验室云南昆明650223

以生物质废弃物酸角壳为原料,通过KOH活化制备酸角壳基活性炭(HHC),采用傅里叶变换红外光谱、扫描电子显微镜表征。酸角壳基活性炭吸附亚甲基蓝(MB)的研究表明:吸附是自发进行,吸热,增加混乱度有利于吸附进行;准二级吸附动力学方程及Lan... 详细信息

以生物质废弃物酸角壳为原料,通过KOH活化制备酸角壳基活性炭(HHC),采用傅里叶变换红外光谱、扫描电子显微镜表征。酸角壳基活性炭吸附亚甲基蓝(MB)的研究表明:吸附是自发进行,吸热,增加混乱度有利于吸附进行;准二级吸附动力学方程及Langmuir等温吸附模型能较好拟合吸附过程。以3 mol/L KOH为电解液,在三电极体系下测定HHC制备的超级电容器电极的循环伏安、恒流充放电、循环性能和交流阻抗。结果显示,电流密度为5 A/g时,首次放电比电容为100 F/g,循环20次后容量保持率为100%,具有较好的循环性能,适合用作超级电容器电极材料。

关键词：生物质废弃物亚甲基蓝吸附机理超级电容器电化学性能

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