检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

数智赋能儿童便捷就医的实践与效果分析

医院管理论坛 2024年第9期41卷 48-50页

作者：康孟利赵伟周明明赵煜峰戴灵杭州市儿童医院

本研究旨在通过深入了解患者、医护人员以及医疗管理部门的实际需求,对现有的就医流程进行全面梳理与分析,找出其中的瓶颈和不足之处,优化就诊模式,为儿童就医提供更为便捷和高效的体验。本研究通过确立任务清单、流程重组设计及应用程... 详细信息

本研究旨在通过深入了解患者、医护人员以及医疗管理部门的实际需求,对现有的就医流程进行全面梳理与分析,找出其中的瓶颈和不足之处,优化就诊模式,为儿童就医提供更为便捷和高效的体验。本研究通过确立任务清单、流程重组设计及应用程序设计,实现数智化赋能,以优化儿童就医体验。通过对2023年10月—11月医院发热门诊平均就诊时间的数据分析显示,应用自助检验开单流程的患者,平均就诊时间显著低于使用传统流程的患者(p<0.05),验证了优化策略的有效性。

关键词：数智化儿童就医流程优化就诊效率

Optimal Timing of Business Conversion for Solvency Improvement

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2024年第3期40卷 744-757页

作者： Peng LI ming zhou School of Finance Nanjing University of Finance and EconomicsNanjing 210023China Center for Applied Statistics and School of Statistics Renmin University of ChinaBeijing 100872China

In this paper,we study the optimal timing to convert the risk of business for an insurance company in order to improve its *** cash flow of company evolves according to a jump-diffusion *** conversion option offers the company an opportunity to transfer the jump risk business *** exchange for this option,the company needs to pay both fixed and proportional transaction *** proportional cost can also be seen as the profit loading of the jump risk *** formulated this problem as an optimal stopping *** solving this stopping problem,we find that the optimal timing of business conversion mainly depends on the profit loading of the jump risk business.A larger profit loading would make the conversion option *** fixed cost,however,only delays the optimal timing of business *** the end,numerical results are provided to illustrate the impacts of transaction costs and environmental parameters to the optimal strategies.

关键词： optimal stopping jump-diffusion process conversion option

Investigation on UV-curing Reprocessable Thermosets Bearing Hindered Urea Bonds and Their Composites with Modified Zinc Oxide Nanoparticles

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第6期42卷 751-765页

作者： Jun-Hao zhou Li-ming Tang Key Laboratory of Advanced Materials of Ministry of Education of China Department of Chemical EngineeringTsinghua UniversityBeijing100084China

In this study,a series of hindered urea bond(HUB)containing polyurethane-urea methacrylate prepolymers and a none HUB containing polyurethane methacrylate prepolymer were prepared using isobornyl methacrylate as the reactive diluent via one-pot *** prepolymers were characterized fully by various ***,their thermosets were fabricated via UV curing in presence of a photo initiator,and their mechanical property and thermal behavior were investigated and *** from the none HUB containing thermoset,the HUB containing thermosets(defined as PUT)could be recycled and reprocessed by hot press under relatively mild conditions with high recovery ratio of mechanical ***,zinc oxide(ZnO)nanoparticles were modified with 3-(trimethoxysilyl)propyl methacrylate and the modified ZnO(defined as ZnO-TPM)was dispersed and polymerized into PUT matrix to prepare their *** influence of ZnO-TPM on the mechanical performance of the composites was evaluated,which indicated that the Young’s modulus and tensile strength increased gradually to the maximum values at ZnO-TPM content of 1 wt%and then *** composites also displayed good reprocessability with improved recovery ratio compared to the pure PUT *** addition,the composite materials exhibited strong UV absorption capacity,implying their potential application in the circumstance where UV-shielding was required.

关键词： Polyurethane-urea methacrylate Hindered urea bond ZnO nanoparticles Reprocessing UV curing

Identification of the genetic locus associated with the crinkled leaf phenotype in a soybean(Glycine max L.)mutant by BSA-Seq technology

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2022年第12期21卷 3524-3539页

作者： Kingsley OCHAR SU Bo-hong zhou ming-ming LIU Zhang-xiong GAO Hua-wei Sobhi FLAMLOM QIU Li-juan National Key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081P.R.China College of Agriculture Northeast Agricultural University/Key Laboratory of Soybean BiologyMinistry of EducationHarbin 150030P.R.China School of Agriculture Yangtze UniversityJingzhou 434025P.R.China Plant Production Department Faculty of Agriculture Saba BashaAlexandria UniversityAlexandria 21531Egypt

The leaf is the main photosynthetic organ of plants,and it plays a significant role in the yield of crop *** the causal mutations and candidate genes that underlie leaf phenotypic variation is an important breeding target in soybean grain yield *** ethyl methyl sulfonate(EMS)-induced soybean mutant DWARFCRINKLEDLEAF1(DCL1)with an aberrant crinkled leaf phenotype was identified in the background of the soybean cultivar Zhongpin 661(Zp661).We constructed an F2 segregating population from a cross between Zp661 and DCL1 in order to investigate the genomic locus associated with the crinkled leaf *** bulk segregant analysis(BSA)combined with the whole-genome resequencing method,the Euclidean distance(ED)correlation algorithm detected 12 candidate genomic regions with a total length of 20.32 Mb that were linked to the target *** a comparative analysis of the sequence data for the wild-type and mutant pools,only one single nucleotide mutation(C:G>T:A)located on the first exon of Glyma.19G207100 was found to be associated with the *** gene validation based on a CAPS marker derived from the detected single-nucleotide polymorphism(SNP)indicated a nucleotide polymorphism between the two ***,our findings reveal that Glyma.19G207100,which is renamed as GLYCINE MAX DWARF CRINKLED LEAF 1(GmDCL1),is a promising candidate gene involved in the morphogenesis of the crinkled leaf trait of the soybean mutant *** study provides a basis for the functional validation of this gene,with prospects for soybean breeding targeting grain yield enhancement.

关键词： soybean mutant crinkled leaf BSA GmDCL1

Manufacturing task data chain-driven production logistics trajectory analysis and optimization decision making method

在线全文

学校读者我要写书评

暂无评论

Advances in Manufacturing 2024年第1期12卷 185-206页

作者： Lin Ling Zhe-ming Song Xi Zhang Peng-zhou Cao Xiao-Qiao Wang Cong-Hu Liu ming-zhou Liu School of Mechanical Engineering Hefei University of TechnologyHefei230009People’s Republic of China Guobo Electronics Co.Ltd. Nanjing211111People’s Republic of China School of Mechanical and Electronic Engineering Suzhou UniversitySuzhou234000AnhuiPeople’s Republic of China Sino-US Global Logistics Institute Shanghai Jiao Tong UniversityShanghai200030People’s Republic of China

Production logistics(PL)is considered as a critical factor that affects the efficiency and cost of production operations in discrete manufacturing *** effectively utilize manufacturing big data to improve PL efficiency and promote job shop floor economic benefits,this study proposes a PL trajectory analysis and optimization decision making method driven by a manufacturing task data chain(MTDC).First,the manufacturing task chain(MTC)is defined to characterize the discrete production process of a *** handle manufacturing big data,the MTC data paradigm is designed,and the MTDC is ***,the logistics trajectory model is presented,where the various types of logistics trajectories are extracted using the MTC as the search engine for the *** on this,a logistics efficiency evaluation indicator system is proposed to support the optimization decision making for the ***,a case study is applied to verify the proposed method,and the method determines the PL optimization decisions for PL efficiency without changing the layout and workshop equipment,which can assist managers in implementing the optimization decisions.

关键词： Production logistics(PL) Logistics trajectory analysis Logistics optimization Data driven Manufacturing task data chain(MTDC)

Dopamine Switches Affective States Under Acute Sleep Deprivation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neuroscience Bulletin 2024年第8期40卷 1205-1208页

作者： zhou-Cai Luo Tian-ming Gao State Key Laboratory of Organ Failure Research Key Laboratory of Mental Health of the Ministry of EducationGuangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired IntelligenceGuangdong-Hong Kong Joint Laboratory for Psychiatric DisordersGuangdong Province Key Laboratory of Psychiatric DisordersGuangdong Basic Research Center of Excellence for Integrated Traditional and Western Medicine for Qingzhi DiseasesDepartment of NeurobiologySchool of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515China

The transition of affective states manifests affective regulation,wherein individuals adaptively adjust their emotional states to cope with changes in the external environment,reflecting their sensitivity and adaptability to environmental *** process of affective state transition is complex,involving both instantaneous and persistent changes influenced by environmental,behavioral,and pharmacological *** underlying neural mechanisms encompass alterations in neurotransmitter release,neural circuit activity,and the plasticity of brain structures[1].

关键词： alterations Dopamine neural

3-芳氧基-1-丙胺类HIV-1 Tat/PCAF BRD抑制剂的合成及生物活性

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

化学学报 2006年第11期64卷 1151-1156页

作者：李家明汪志勇 ZENG,Lei zhou,ming-ming 中国科学技术大学化学系合肥230026 Structural Biology Program Department of Physiology and Biophysics Mount Sinai School of Medicine New York University New York 10029-6574 U. S. A.

为了研究HIV-1Tat/PCAFBRD抑制剂的构效关系,合成了6个3-芳氧基-1-丙胺类化合物.以取代的2-硝基苯酚为起始原料,在常规加热和微波辐射加热下与1,3-二溴丙烷反应合成3-(2-硝基芳氧基)-1-溴丙烷(3),结果显示,微波辐射加热比常规加热下的... 详细信息

为了研究HIV-1Tat/PCAFBRD抑制剂的构效关系,合成了6个3-芳氧基-1-丙胺类化合物.以取代的2-硝基苯酚为起始原料,在常规加热和微波辐射加热下与1,3-二溴丙烷反应合成3-(2-硝基芳氧基)-1-溴丙烷(3),结果显示,微波辐射加热比常规加热下的反应速度明显加快,收率有所提高.3和邻苯二甲酰亚胺钾进行N-烷基化反应合成了2-[3-(芳氧基)-丙基]二氢异吲哚-1,3-二酮,再经肼解得到了目标化合物,所有化合物的结构均经FTIR,1HNMR,13CNMR及HRMS确证.ELISA检测法测定了它们体外抑制HIV-1Tat/PCAFBRD的活性,并对影响活性的因素进行了讨论.

关键词： 3-芳氧基-1-丙胺盐酸盐微波辐射肼解 Gabriel反应抗HIV-1

Monitoring of Cell Membrane Microenvironment Based on DNA Nanodevices

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第2期40卷 255-267页

作者： NAN Hexin CAI ming KUANG Shi NIE zhou State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan Provincial Key Laboratory of Biomacromolecular Chemical BiologyHunan UniversityChangsha410082P.R.China

The cell membrane is a critical barrier for cellular homeostasis,integral to signaling and intercellular communication,and vital for understanding cellular functions and disease *** its microenvironment is crucial for uncovering the molecular basis of physiological and pathological processes associated with the cell membrane,driving the development of bioanalytical toolkits capable of dynamically monitoring the cell surface *** the continuous advancement of functional nucleic acids and dynamic DNA nanotechnology,DNA nanodevices with controllable nanosized geometry,specific molecular recognition,and selective membrane-localization properties offer a versatile platform for probing the cell membrane *** this review,we summarize the current biosensing and membrane-anchoring mechanisms of DNA nanodevices and highlight their use in studying key cell membrane events,including membrane lipid dynamics,transmembrane transport,receptor dimerization,and signal ***,we discuss the challenges and potential future applications of DNA nanodevices in advancing cell membrane biology research and biomedical applications.

关键词： DNA nanodevice Cell membrane Cellular micro-environment Monitoring

A review of MXene-derived quantum dots:Synthesis,characterization,properties,and applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2024年第8期91卷 50-71页

作者： Chunhe zhou Kar Ban Tan Wenjuan Han Li Wang ming Lu The Joint Laboratory of MXene Materials Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of EducationJilin Normal UniversityChangchunJilin 130103China Department of Chemistry Faculty of ScienceUniversiti Putra MalaysiaSerdangSelangor 43400Malaysia

Cutting MXene to a minimum size and forming the derived two-dimensional MXene quantum dots(MQDs),which possess a unique intrinsic layered geometry structure,restricts exciton due to their novel spatial *** gives rise to a broad spectrum of fascinating properties,rendering them for various ***,the correlation between composition,structure,and processing control of MQDs is investigated systematically,giving further insight into the intrinsic and extrinsic *** review also provides an opportunity to explore new compositions,modify the properties,and tailor MQDs into the guided architectural design before any prospective applications.

关键词： MXene Quantum dots Characterization Properties Applications