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Relationship between alanine aminotransferase levels and metabolic syndrome in nonalcoholic fatty liver disease

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第8期9卷 616-622页

作者： zhou-wen CHEN li-ying CHEN Hong-lei DAI Jian-hua CHEN li-zheng FANG Department of General Practice Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou 310016 China

Objective： To investigate the relationship between alanine aminotransferase （ALT） levels and metabolic syndrome （MS） in nonalcoholic fatty liver disease （NAFLD）. Methods： A total of 26527 subjects who received medical health checkup in our hospital from January 2005 to July 2007 were enrolled in the study. The diagnosis of fatty liver was based on ultrasound imaging. MS was defined according to the criteria of the Adult Treatment Panel III. ALT, triglyceride （TG）, high density lipoprotein cholesterol （HDL-c）, fasting plasma glucose （FPG）, height, weight, waist circumference （WC）, systolic blood pressure （SBP） and diastolic blood pressure （DBP） were measured in each subject to analyze the relationship between MS and ALT activity Results：（1） The prevalence of NAFLD in men （30.94%） was significantly higher than that in women （15.65%）; （2） The incidence of MS in NAFLD （33.83%） was significantly greater than that in non-NAFLD （10.62%）; （3） Of the 6470 subjects with NAFLD, in the age-adjusted partial correlation analysis, there were statistically significant correlations between the ALT levels and most metabolic risk factors in each sex （P〈0.01）, except that ALT levels multiple stepwise regression analysis, SBP lost its significance, and had no correlation with HDL-c in women. Moreover, in the WC, body mass index （BMI）, age, DBP, TG and FPG were independently associated with ALT levels in both sexes （P〈0.05）. HDL-c remained significant and was independently related to ALT levels in men; （4） ALT levels were significantly higher in subjects with MS compared to those without MS （P〈0.001）. Mean ALT levels increased with the number of MS components in each sex （P〈0.05 for trend）. Conclusion： We found a strong relationship between ALT levels and MS in NAFLD and revealed that the cluster of MS components might be the predictor for ALT elevations.

关键词： Nonalcoholic fatty liver disease (NAFLD) Alanine aminotransferase (ALT) Metabolic syndrome (MS)

EFFECTS OF TRANSCRANIAL MAGNETIC STIMULATION ON MOTOR CORTICAL EXCITABIliTY AND NEUROFUNCTION AFTER CEREBRAL ISCHEMIA-REPERFUSION INJURY IN RATS

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Chinese Medical Sciences Journal 2005年第4期20卷 226-230,页

作者： Hong-lin Feng li Yan Yu-zhou Guan li-ying Cui Department of Neurology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730

Objective To clarify the effects of repetitive transcranial magnetic stimulation (rTMS) on rat motor cortical excitabi- lity and neurofunction after cerebral ischemia-reperfusion injury. Methods After determined awake resting motor threshold (MT) and motor evoked potentials (MEPs) of right hindlimbs, 20 Sprague-Dawley rats were subjected to middle cerebral artery occlusion (MCAO) reperfusion injury, then rTMS were applied to rTMS group (n = 10) at different time, while control group (n = 10) received no stimulation. A week later, MT and MEPs were evaluated again, as well as neurological deficits and infarct volume. The effects of rTMS and MCAO reperfusion injury on these parameters were analyzed. Results After MCAO reperfusion, both MT level and neurological deficit scores increased, distinct focal infarction formed, and latency of MEP elongated. Compared with the control group, the increased extent of MT and neurological scores of rats receiving rTMS were significantly lower (P linear correlation between postinjury MT and infarct volume (r = 0.64, P litate neurofunction recovery after cerebral ischemia-reperfusion. Postinjury MT could provide prognostic information after MCAO reperfusion injury.

关键词： repetitive transcranial magnetic stimulation cerebral ischemia-reperfusion.injury motor threshold motor evoked potential

Epidemiological Investigation of Risk Factors of the Pregnant Women with Early Spontaneous Abortion in Beijing

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Chinese Journal of Integrative Medicine 2017年第5期23卷 345-349页

作者： zhou li-ying ZHANG Hong-xia LAN Yong-lian li ying liANG Yu YU Lan MA Yan-min JIA Chan-wei WANG Shu-yu Department of Reproduction Beijing Obstetrics and Gynecology Hospital Capital Medical University Beijing (100026) China Department of Reproduction Peking University Third Hospital Beijing (100191 ) China

Objective： To determine the risk factors of the pregnant women with early spontaneous abortion in Beijing. Methods： A total of 34,417 cases of pregnant women were participated in the survey from January 2000 to December 2013. A questionnaire was informed to each woman. The content of questionnaire includes four parts： general condition, obstetrical history, past history and family history, and living environment and habits. The mental condition was evaluated with Self-Rating Anxiety Scale（SAS） and Self-Rating Depression Scale（SDS）. Results： A total of 32,296 questionnaires were collected. The spontaneous abortion rate in the total sample was 3.0%. There was no significant difference between the normal pregnancy group and spontaneous abortion group in terms of general condition, obstetrical and past history（P〉0.05）. Significant differences between the two groups were found in terms of decoration during pregnancy, keeping pets, near mobile communication base station within 100 m around the residence, drinking during pregnancy, having a cold during pregnancy and SAS（P〈0.05）. Having a cold during pregnancy, decoration during pregnancy, near mobile communication base station within 100 m around the residence, keeping pets and high SAS were determined the independent risk factors of spontaneous abortion by Logistic regression analysis. Conclusions： Having a cold during pregnancy, decoration, keeping pets, near mobile communication base station within 100 m around the residence and high SAS are the independent risk factors of spontaneous abortion in Beijing.

关键词： epidemiological risk factors spontaneous abortion living environment habit

Nanostructured ZnO/BiVO_(4)I-scheme heterojunctions for piezocatalytic degradation of organic dyes via harvesting ultrasonic vibration energy

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 488-497页

作者： Yiling li Xiaoyao Yu yingjie zhou Yao lin ying Wu Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004China

BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step *** resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degrading Rhodamine B(RhB)unde mechanical vibrations,they exhibit superior activity compared to pure *** 40wt%ZnO/BiVO_(4)heterojunction composite displayed the highest activity,along with good stability and *** enhanced piezoelectric catalytic activity can be attributed to the form ation of an I-scheme heterojunction structure,which can effectively inhibit the electron-hole ***,hole(h+)and superoxide radical(·O_(2)^(-))are proved to be the primary active ***,ZnO/BiVO_(4)stands as an efficient and stable piezoelectric catalyst with broad potential application in the field of environmental water pollution treatment.

关键词： piezoelectric catalytic heterojunction dye degradation ultrasonic vibration

Design of Digital Control System for Cement Raw Material Preparation

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武汉理工大学学报 2006年第S3期28卷 1157-1160页

作者： zhou ying li Hongsheng School of Automation,Wuhan University of Technology,Wuhan 430070,China School of Automation Wuhan University of TechnologyWuhan 430070China

This paper describes the design of cement raw material prepared digital control system by *** uses the digital technology to implement the digital control system for raw material prepared of the cement *** system improves the communication between the industrial system and locale instrument *** applies digital communication to replace ttle 4-20 mA or 24VDC signal between locale lever device and controller.

关键词： digital CIMS PROFIBUS

Asynchronization in Changes of Electrophysiology and Pathology of Spinal Cord Motor Neurons in Rats Following Middle Cerebral Artery Occlusion

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Chinese Medical Journal 2015年第21期128卷 2919-2925页

作者： Nan lin Ming-Sheng liu Si-Yuan Fan Yu-zhou Guan li-ying Cui Department of Neurology Peking Union Medical College Hospital Beijing 100730 China

Background： Motor dysfunction is common in stroke patients. Clinical electrophysiological studies suggest that transsynaptic degeneration occurred in the lower motor neurons, while pathological evidence is lacked. This study aimed to combine the electrophysiological and pathological results to prove the existence of transsynaptic degeneration in the motor system after stroke. Methods： Modified neurologic severity score, electrophysiological, and pathological assessments were evaluated in rats before middle cerebral artery occlusion （MCAO）, and at 24 hours, 7 days, and 14 days after MCAO. Paired and independent-sample t-tests were applied to assess the changes of electrophysiological and pathological data. Results： Compound motor action potential amplitude in the paretic side was significantly lower than the nonparetic side at both 24 hours （61.9 ± 10.4 vs. 66.6 ± 8.9, P 〈 0.05） and 7 days （60.9 ± 8.4 vs. 67.3 ±9.6, P 〈 0.05） after MCAO. Motor unit number estimation of the paretic side was significantly less than the nonparetic side （379.0 ± 84.6 vs. 445.0 ±9.5, P 〈 0.05） at 7 days after MCAO. Until 14 days after stroke, the pathological loss of motor neurons was detected. Motor neurons in 14-day MCAO group were significantly decreased, compared with control group （5.3 ± 0.7 vs. 7.3 ± 1.8, P 〈 0.05）. Conclusions： Both electrophysiological and pathological studies showed transsynaptic degeneration after stroke. This study identified the asynchronization in changes of electrophysiology and pathology. The abnormal physiological changes and function impairment can be detected in the early stage and recovered quickly, while the pathological loss of motor neuron can be detected only in a later stage.

关键词： Middle Cerebral Artery Occlusion Electrophysiology Lower Motor Neurons Pathology Stroke

Recent development in electrode design for wide-temperature supercapacitors

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Science China Chemistry 2025年第1期68卷 96-117页

作者： Jianhong liu Qiang zhou Yuxiao lin Xinsheng Zhao Guangmin zhou Xiaoxiao li School of Physics and Electronic Engineering Jiangsu Normal University Tsinghua-Berkeley Shenzhen Institute & Tsinghua Shenzhen International Graduate School Tsinghua University

An ever-increasing market demand has stimulated the soaring enthusiasm of researchers to develop wide-temperature supercapacitors(SCs). The active electrode is one of the most important parts of SC, which is directly related to the energy density,power transmission and long-term cyclability of the device in the wide-temperature environment. Compared with the SC electrodes aimed for room-temperature application, the SC electrodes for operating at wide-temperature scene often face greater challenges. In this review, the main challenges of SC electrodes under various temperature conditions, including low, high and cross-fade temperatures, are summarized. The relevant performance decay and failure mechanisms of wide-temperature SC electrodes are analyzed. In addition, this review deals with the recent studies and developments in robust wide-temperature SC electrodes with respect to the rational design of electrode structures and the exploitation of advanced active materials. Finally, the future directions for exploring reliable wide-temperature SCs are also proposed.

关键词： supercapacitor wide-temperature electrode design active materials

Fine-tuning the spatial allocation of phytohormones for smart canopy, smart breeding, and smart agriculture

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Science China life Sciences 2025年第1期68卷 309-310页

作者： Tao zhou lin li National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University HuBei HongShan Laboratory

The dual challenges of global climate change and population growth have increased demand for higher crop yields per unit area. The innovative technology of smart agriculture aims to synergize breeding, cultivation, and production through the application of biological and informatics technologies. Historically, the “Green Revolution” introduced semidwarf varieties of certain key crops by utilizing mutations affecting gibberellin pathways, which significantly increased planting densities and yields.

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从《云南》、《滇话》看晚清云南留日学生的近代思想

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云南民族大学学报（哲学社会科学版） 2007年第4期24卷 103-108页

作者：周立英云南大学人文学院云南昆明650091

在近代中国的留学浪潮中,大批有志青年来到日本,创办了大量进步报刊,宣传革命思想和爱国主义。从云南留日学生创办的《云南》杂志和《滇话》报刊可以看出晚清云南留日学生的国民思想、国家观念、云南观和社会改良思想,他们将个人命运与... 详细信息

在近代中国的留学浪潮中,大批有志青年来到日本,创办了大量进步报刊,宣传革命思想和爱国主义。从云南留日学生创办的《云南》杂志和《滇话》报刊可以看出晚清云南留日学生的国民思想、国家观念、云南观和社会改良思想,他们将个人命运与国家前途紧密联系在一起,并积极倡导女子教育、风俗改革等社会改良思想。

关键词：《云南》《滇话》留日学生近代思想