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Serum Gamma-glutamyl Transferase Levels Predict Functional Outcomes after Aneurysmal Subarachnoid Hemorrhage

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Biomedical and Environmental Sciences 2017年第3期30卷 170-176页

作者： XU Tian WANG Wei ZHAI Lin ZHANG Yun Feng zhou hong zhi WU Xin Min LI Ai hong XIE Li Li NING Xiao Jin JI Yu Teng WANG hong Mei KE Kai Fu Department of Neurology Affiliated Hospital of Nantong UniversityNantong 226001JiangsuChina Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjing 210006JiangsuChina Medical record center Affiliated Hospital of Nantong UniversityNantong 226001JiangsuChina Neurology research institute of Nantong University Nantong 226001JiangsuChina

Objective We aim to explore the potential association between serum gamma-glutamyl transferase levels and functional outcome after aneurysmal subarachnoid hemorrhage in a Chinese population. Methods A total of 386 aneurysmal subarachnoid hemorrhage patients were included in the study from September 2007 to February 2015. Baseline serum gamma-glutamyl transferase levels and 6-month follow-up functional outcomes were determined. A poor outcome was defined as a modified ranking scale score of ≥ 3. The multivariable logistic model was used to analyze the relationship between serum gamma-glutamyl transferase and clinical outcomes after aneurysmal subarachnoid hemorrhage. Results The adjusted poor outcome rates of patients with gamma-glutamyl transferase levels of 〈 30 U/L, 30-50 U/L and ≥ 50 U/L were 16.7%, 19.6%, and 34.4%, respectively （P 〈 0.01）. The age-sex and multivariable adjusted odds ratios （95% confidence intervals） of poor prognosis comparing the top group （≥ 50 U/L） with the lowest group （〈 30 U/L） were 5.76 （2.74-12.13）, 6.64 （2.05-21.52）, and 6.36 （1.92-21.02）. A significant linear trend existed between gamma-glutamyl transferase level and aneurysmal subarachnoid hemorrhage prognosis. This association was also observed among nondrinkers. Conclusion Patients with higher gamma-glutamyl transferase levels were more likely to have a poor prognosis. Serum gamma-glutamyl transferase can be considered to be an independent predictor of functional outcomes after aneurysmal subarachnoid hemorrhage.

关键词： Aneurysmal subarachnoid hemorrhage Gamma-glutamyl transferase Functional outcome Predictor

An Enhanced Automated Signature Generation Algorithm for Polymorphic Malware Detection

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Journal of Electronic Science and Technology 2010年第2期8卷 114-121页

作者： Ke Tang Ming-Tian zhou zhi-hong Zuo School of Computer Science and Engineering University of Electronic Science and Technology of China Chengdu 610054 China

Polymorphic malware is a secure menace for application of computer network systems because hacker can evade detection and launch stealthy attacks. In this paper, a novel enhanced automated signature generation （EASG） algorithm to detect polymorphic malware is proposed. The EASG algorithm is composed of enhanced-expectation maximum algorithm and enhanced K-means clustering algorithm. In EASG algorithm, the fixed threshold value is replaced by the decision threshold of interval area. The false positive ratio can be controlled at low level, and the iterative operations and the execution time are effectively reduced. Moreover, the centroid updating is realized by application of similarity metric of Mahalanobis distance and incremental learning. Different malware group families are partitioned by the centroid updating.

关键词： Index Terms -Entropy false positive ratio Mahalanobis distance polymorphie malware signature generation.

Regulation of swelling-activated chloride channels in embryonic chick heart cells

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Cell Research 2003年第1期13卷 21-28页

作者： HUA WEI, VAN AI MEI, JIA TING SUN, HAN QING zhou, zhi hong ZHANGDepartment of Physiology and Biophysics, Liren Laboratory, School of Life Sciences, Fudan University, Shanghai 200433, China Fishery College, Shanghai Fisheries University, Shanghai 200090, China Department of Physiology and Biophysics Liren Laboratory School of Life Sciences Fudan University Shanghai China Fishery College Shanghai Fisheries University Shanghai China

Swelling-activated Cl- currents, I(ci,swell), were measured during hyposmotic shock in white Leghorn embryonic chick heart cells using the whole-cell recording of patch-clamp technique. Genistein, an inhibitor of protein tyrosine kinase (PTK), suppressed I(ci,swell), Under isosmotic condition phorbol 12-myristate 13-acetate (PMA), an activator of PKC, elicited the Cl~ current similar to that in hyposmotic solution, whereas hyposmotic shock did not elicit I(ci,swell) in chelerythrine chloride(an inhibitor of PKC)-treated cells. Con-focal microscopy experiments using FITC-phalloidin as a fluorescent label of F-actin showed that the actin network was moved from cortical region of the cell to the center after hyposmotic shock as compared with the image under isosmotic condition. When the cells were treated with cytochalasin B (CB) or cytochalasin D (CD) under isosmotic condition the disruption of the F-actin integrity was observed, and I(ci,Sweii) was not elicited. With combination treatment of CB with PMA,

关键词： swelling activation myocardium chloride current F-actin phosphorylation.

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无梭织机的选型及其应用

棉纺织技术 1989年第1期17卷 27-29,26页

作者：邹志鸿无锡第一棉纺织厂

本文从品种适应性、高难度织物的承担能力、织物的品质、入纬率和经济效益等方面对各种无梭织机的技术参数、工艺性能作了分析比较。并提出了提高无梭织机生产水平的四点建议,可供参考。

关键词：织机工艺性能技术参数

Tailoring Light–Matter Interactions in Overcoupled Resonator for Biomolecule Recognition and Detection

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Nano-Micro Letters 2025年第1期17卷 262-280页

作者： Dongxiao Li hong zhou zhihao Ren Cheng Xu Chengkuo Lee Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Center for Intelligent Sensors and MEMS(CISM) National University of SingaporeSingapore 117608Singapore

Plasmonic nanoantennas provide unique opportunities for precise control of light–matter coupling in surface-enhanced infrared absorption(SEIRA)spectroscopy,but most of the resonant systems realized so far suffer from the obstacles of low sensitivity,narrow bandwidth,and asymmetric Fano resonance ***,we demonstrated an overcoupled resonator with a high plasmon-molecule coupling coefficient(μ)(OC-Hμresonator)by precisely controlling the radiation loss channel,the resonator-oscillator coupling channel,and the frequency detuning *** observed a strong dependence of the sensing performance on the coupling state,and demonstrated that OC-Hμresonator has excellent sensing properties of ultra-sensitive(7.25%nm^(−1)),ultra-broadband(3–10μm),and immune asymmetric Fano *** characteristics represent a breakthrough in SEIRA technology and lay the foundation for specific recognition of biomolecules,trace detection,and protein secondary structure analysis using a single array(array size is 100×100μm^(2)).In addition,with the assistance of machine learning,mixture classification,concentration prediction and spectral reconstruction were achieved with the highest accuracy of 100%.Finally,we demonstrated the potential of OC-Hμresonator for SARS-CoV-2 *** findings will promote the wider application of SEIRA technology,while providing new ideas for other enhanced spectroscopy technologies,quantum photonics and studying light–matter interactions.

关键词： Plasmonic nanoantennas Light-matter interaction Surface-enhanced infrared absorption Overcoupled Biosensing

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一种改进的梯度直方图远红外行人检测方法

四川大学学报（自然科学版） 2016年第5期53卷 1018-1026页

作者：周红志刘祺阜阳师范学院信息工程学院阜阳236041 华南理工大学计算机科学与工程学院广州510640

在远红外行人检测领域,实时性以及鲁棒性如何提高,这一问题一直得不到有效的解决.笔者以感兴趣区域ROIs为切入点,在图像预处理阶段充分应用像素梯度相关知识,总结出有效的垂直投影方法.该方法原理为:搜集图像梯度信息,采用初定位方法对... 详细信息

在远红外行人检测领域,实时性以及鲁棒性如何提高,这一问题一直得不到有效的解决.笔者以感兴趣区域ROIs为切入点,在图像预处理阶段充分应用像素梯度相关知识,总结出有效的垂直投影方法.该方法原理为:搜集图像梯度信息,采用初定位方法对垂直方向上的条状区域展开处理并获取包括行人在内的图像,采取局部双阈值图像分割算法获得相对较为可靠性ROIs,避免对整幅输入图像进行搜索.检测过程中,充分发挥全局信息作用,采用以金字塔熵加权的梯度直方图方法,针对远红外行人进行描述.本方法引入了支持向量机算法的识别技术.文章最后针对该方法进行了实验检验.实验结果显示,该方法大大缩短了ROIs提取过程的搜索耗时,而且可以对一些以背景目标为主的候选区域进行抑制.

关键词：行人检测 ROIs 像素梯度双阈值梯度直方图 SVM算法

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基于Nagle算法的嵌入式TCP协议

浙江大学学报（工学版） 2006年第1期40卷 41-44,56页

作者：周志洪王勇陈抗生浙江大学信息与电子工程学系浙江杭州310027

针对在8/16位低速处理器上实现传输控制协议(Transfer Control Protocol TCP)过于复杂的问题,通过对TCP协议进行简化,减轻了微处理器的运算负担,降低了对系统存储空间的要求,使得TCP协议能够在8/16位低速处理器上实现.嵌入式网络中大量... 详细信息

针对在8/16位低速处理器上实现传输控制协议(Transfer Control Protocol TCP)过于复杂的问题,通过对TCP协议进行简化,减轻了微处理器的运算负担,降低了对系统存储空间的要求,使得TCP协议能够在8/16位低速处理器上实现.嵌入式网络中大量使用长度很小的数据帧,使得网络带宽利用率极低,为此在协议中应用了Na-gle算法,减少了协议所需带宽,提高了协议的吞吐率.采用NS-2(Network Simulator-2)进行的仿真结果表明:该方案是有效的,现已经在普通8位处理器上实现,并通过了在多种宽带网络上进行的测试,在网络电能表中得到了实际应用.

关键词：嵌入式因特网传输控制协议 Nagle算法 NS-2

Research on Order Quantity Simulation

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International Journal of Plant Engineering and Management 2003年第2期8卷 122-128页

作者： zhou hong, LI zhi-cheng Management School, Huazhong University of Science & Technology, Wuhan 430074, P.R.China Management School Huazhong University of Science & Technology Wuhan 430074 P. R. China

The order quantity is often affected by various factors, so it is morevaluable to research the problem of evaluating the order quantity based on a less premise. In thispaper, a complicated order quantity problem is studied and an order quantity simulation system isestablished with the simulation software of ARENA. Finally, an example is given.

关键词： inventory theory simulation order quantity

牵引成骨技术在下颌骨节段性缺损修复中的应用

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中华口腔医学杂志 2005年第2期40卷 175-176页

作者：周宏志胡敏刘洪臣解放军总医院口腔科

20世纪90年代,基于Ilizarov[1,2]的长期研究成果,牵引成骨(distraction osteogenesis,DO)技术在颌面外科领域得到重要发展[3,4],早在1973年Snyder等[5]报告了下颌骨缺损的DO修复实验,Shwyrkow和Shamsudinov[6]最早将其应用于临床缺损病... 详细信息

关键词：牵引成骨技术下颌骨节段性缺损修复临床应用