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A novel flexible nerve guidance conduit promotes nerve regeneration while providing excellent mechanical properties

Neural Regeneration Research 2025年第7期20卷 2084-2094页

作者： Tong Li Quhan Cheng Jingai Zhang Boxin Liu Yu Shi Haoxue Wang Lijie Huang Su Zhang Ruixin Zhang Song Wang Guangxu Lu Peifu Tang zhongyang Liu Kai Wang Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijingChina Department of Training and Sports Medicine Characteristic Medical Center of Chinese People’s Armed Police ForceTianjinChina Medical School of Chinese PLA BeijingChina Key Laboratory of Bioactive Materials for the Ministry of Education College of Life SciencesNankai UniversityTianjinChina Department of Orthopedics Tianjin HospitalTianjinChina Department of Rehabilitation Medicine Er Quan Hospital of PAPWuxiJiangsu ProvinceChina

Autografting is the gold standard for surgical repair of nerve defects>5 mm in length;however,autografting is associated with potential complications at the nerve donor *** an alternative,nerve guidance conduits may be *** ideal conduit should be flexible,resistant to kinks and lumen collapse,and provide physical cues to guide nerve *** designed a novel flexible conduit using electrospinning technology to create fibers on the innermost surface of the nerve guidance conduit and employed melt spinning to align ***,we prepared disordered electrospun fibers outside the aligned fibers and helical melt-spun fibers on the outer wall of the electrospun fiber *** presence of aligned fibers on the inner surface can promote the extension of nerve cells along the *** helical melt-spun fibers on the outer surface can enhance resistance to kinking and compression and provide *** novel conduit promoted nerve regeneration and functional recovery in a rat sciatic nerve defect model,suggesting that it has potential for clinical use in human nerve injuries.

关键词： aligned fibers anti-kinking helical fibers nerve guidance conduit nerve regeneration peripheral nerve injury topological guidance

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A Multi-Stage Differential-Multifactorial Evolutionary Algorithm for Ingredient Optimization in the Copper Industry

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IEEE/CAA Journal of Automatica Sinica 2024年第10期11卷 2135-2153页

作者： Xuerui Zhang zhongyang Han Jun Zhao School of Control Science and Engineering Dalian University of TechnologyDalian 116024China IEEE

Ingredient optimization plays a pivotal role in the copper industry,for which it is closely related to the concentrate utilization rate,stability of furnace conditions,and the quality of copper *** acquire a practical ingredient plan,which should exhibit long duration time with sufficient utilization and feeding stability for real applications,an ingredient plan optimization model is proposed in this study to effectively guarantee continuous production and stable furnace *** address the complex challenges posed by this integer programming model,including multiple coupling feeding stages,intricate constraints,and significant non-linearity,a multi-stage differential-multifactorial evolution algorithm is *** the proposed algorithm,the differential evolutionary(DE)algorithm is improved in three aspects to efficiently tackle challenges when optimizing the proposed ***,unlike traditional time-consuming serial approaches,the multifactorial evolutionary algorithm is utilized to optimize multiple complex models contained in the population of evolutionary algorithm caused by the feeding stability in a parallel ***,a repair algorithm is employed to adjust infeasible ingredient lists in a timely *** addition,a local search strategy taking feedback from the current optima and considering the different positions of global optimum is developed to avoiding premature convergence of the differential evolutionary ***,the simulation experiments considering different planning horizons using real data from the copper industry in China are conducted,which demonstrates the superiority of the proposed method on feeding duration and stability compared with other commonly deployed *** is practically helpful for reducing material cost as well as increasing production profit for the copper industry.

关键词： Copper industry differential-multifactorial evolution ingredient optimization multi-stage optimization

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Study of the kinetic behaviour of biomass and coal during oxyfuel co-combustion

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Chinese Journal of Chemical Engineering 2020年第7期28卷 1796-1804页

作者： Oris Chansa zhongyang Luo Chunjiang Yu State Key Laboratory of Clean Energy Utilization Zhejiang UniversityHangzhou 310027China

In this study,the thermogravimetric analysis(TGA)method has been used to evaluate the kinetic behavior of biomass,coal and its blends during oxyfuel *** thermogravimetric results have been evaluated by the Coats-Redfern method and validated by Criado’s *** and DTG curves indicate that as the oxygen concentration increases the ignition and burn out temperatures approach a lower temperature *** combustion characteristic index shows that biomass to coal blends of 28%and 40%respectively can achieve enhanced combustion up to 60%oxygen *** the devolatilization region,the activation energies for coal and blends reduce while in the char oxidation region,they increase with rise in oxygen ***,however,indicates slightly different combustion characteristic of being degraded in a single step and its activation energies increase with rise in oxygen *** is demonstrated in this work that oxygen enrichment has more positive combustion effect on coal than *** 20%oxygen enrichment,28%and 40%blends indicate activation energy of 132.8 and 125.5 kJ·mol^-1 respectively which are lower than coal at 148.1 kJ·mol^-1 but higher than biomass at 81.5 kJ·mol^-1 demonstrating synergistic effect of fuel ***,at char combustion step,an increase in activation energy for 28%blend is found to be 0.36 kJ·mol^-1 per rise in oxygen concentration which is higher than in 40%blend at 0.28 kJ·mol^-1.

关键词： Oxyfuel co-combustion Thermogravimetric analysis Kinetic analysis Activation energy Thermal degradation

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Radius of locally convex subsets in Alexandrov spaces with curvature ≥1 and radius 〉 π/2

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Frontiers of Mathematics in China 2014年第2期9卷 417-423页

作者： Yusheng WANG zhongyang SUN School of Mathematical Sciences (and the Key Laboratory on Mathematics and ComplexSystem) Beijing Normal University Beijing 100875 China Center of Mathematical Sciences Zhejia-ng-University Hangzhou 310027 China

Let X be a complete Alexandrov space with curvature ≥1 and radius 〉 π/2. We prove that any connected, complete, and locally convex subset without boundary in X also has the radius 〉 π/2.

关键词： Alexandrov space convex subset radius

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An Optimized Oxygen System Scheduling With Electricity Cost Consideration in Steel Industry

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IEEE/CAA Journal of Automatica Sinica 2017年第2期4卷 216-222页

作者： zhongyang Han Jun Zhao Wei Wang Faculty of Electronics Information and Electrical Engineering Dalian University of Technology IEEE

As an essential energy resource in steel industry, oxygen is widely utilized in many production procedures. With different demands of the oxygen amount, a gap between the generation and consumption always occurs. Therefore, its related optimization and scheduling work along with the electricity cost to fill the gap has a great impact on daily production and efficient energy utilization in steel plant. Considering an oxygen system in a steel plant in China, a nonlinear programming model for oxygen system scheduling is proposed in this study, which concerns not only the practical characteristics of the energy pipeline network, but also the electricity cost acquired by a fitting regression modeling between the load of air separation units U+0028 ASU U+0029 and its corresponding electricity consumption. A set of constraints is formulated for restricting the practical adjusting capacity and filling the imbalance gap of oxygen. To solve the proposed scheduling model with electricity cost consideration, a particle swarm optimization U+0028 PSO U+0029 algorithm is then adopted. To verify the effectiveness of the proposed approach, a large number of experiments employing the real data from this plant are carried out, both for the fitting regression and the scheduling optimization phases. And the results demonstrate that such a practice-based solution successfully resolves the oxygen scheduling problem and simultaneously minimizes the electricity cost, which will be beneficial for the enterprise. © 2017 Chinese Association of Automation.

关键词： Costs Electric power utilization Energy resources Energy utilization Iron and steel industry Nonlinear programming Particle swarm optimization (PSO) Pipe fittings Scheduling Steel metallurgy Steelmaking

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Adaptive Optimal Discrete-Time Output-Feedback Using an Internal Model Principle and Adaptive Dynamic Programming

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IEEE/CAA Journal of Automatica Sinica 2024年第1期11卷 131-140页

作者： zhongyang Wang Youqing Wang Zdzisław Kowalczuk the College of Information Science and Technology Beijing University of Chemical TechnologyBeijing 100029China IEEE the Department of Robotics and Decision Systems Faculty of ElectronicsTelecommunications and InformaticsGdańsk University of TechnologyGdansk 80-233Poland

In order to address the output feedback issue for linear discrete-time systems, this work suggests a brand-new adaptive dynamic programming(ADP) technique based on the internal model principle(IMP). The proposed method, termed as IMP-ADP, does not require complete state feedback-merely the measurement of input and output data. More specifically, based on the IMP, the output control problem can first be converted into a stabilization problem. We then design an observer to reproduce the full state of the system by measuring the inputs and outputs. Moreover, this technique includes both a policy iteration algorithm and a value iteration algorithm to determine the optimal feedback gain without using a dynamic system model. It is important that with this concept one does not need to solve the regulator equation. Finally, this control method was tested on an inverter system of grid-connected LCLs to demonstrate that the proposed method provides the desired performance in terms of both tracking and disturbance rejection.

关键词： Adaptive dynamic programming(ADP) internal model principle(IMP) output feedback problem policy iteration(PI) value iteration(VI)

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ESTIMATION OF ECOLOGICAL SERVICE VALUES OF WETLANDS IN SHANGHAI, CHINA

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Chinese Geographical Science 2005年第2期15卷 151-156页

作者： LIBo zhongyang NAKAGOSHINobukazu CHENJia-kuan MinistryofEducationKeyLaboratoryforBiodiversityScienceandEcologicalEngineering lnstituteofBiodiversityScienceFudanUniversityShanghai200433P.R.China GraduateSchoolforInternationalDerelopmentandCooperation HiroshimaUniversityHigashi-Hiroshima739-8529Japan

Shanghai is a coastal metropolitan city with various types of natural wetlands, which account for 23.5% of its total area. According to the definition of wetland in Ramsar Convention on Wetlands, the wetlands of Shanghai were classified into 4 types: coastal, riverine, lacustrine, and reservoir and pond wetlands. In order to examine the roles of wetlands in the life-support system of Shanghai, we calculated the area of each type of the wetlands using GIS technique, and then measured the ecological service values of different ecosystems in Shanghai based on the classification of ecosystem services proposed by COSTANZA et al. (1997). The estimated annual value of ecosystem services in the study area was 7.3×109US$/a for the total area of 1 356 700ha, among which about 97% was provided by the wetlands. Effective conservation and management of wetlands are therefore crucial to Shanghai’s sustainable development. The limitations of the evaluation method for ecosystem service value were also discussed in the present paper.

关键词： ecosystem service ecological service value GIS Shanghai

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Investigation on Fuel-N Transformation Properties of Coal/Biomass Heating Process in CO_(2)Atmosphere

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Journal of Thermal Science 2021年第4期30卷 1141-1150页

作者： LIN Junjie WANG Qinhui LIANG Xiaorui LUO zhongyang State Key Laboratory of Clean Energy Utilization Zhejiang UniversityHangzhou 310027China

To understand the effect of a CO_(2)atmosphere on the properties of the transformation from fuel-N to NO_(x)precursors(mainly NH_(3)and HCN),pyrolysis experiment on Pingliang coal(PL coal),wheat straw and their corresponding blends was carried out in a fluidized bed reactor within a temperature range of 750℃to 850℃.The results indicated that the PL coal and wheat straw show different NO_(x)precursor formation properties owing to the discrepancy between the N-containing structures in the raw *** with an argon atmosphere,CO_(2)can effectively suppress the formation of NH_(3).For HCN,the HCN yield of PL coal is suppressed and the HCN yield of wheat straw is ***,CO_(2)can suppress the overall nitrogen conversion rate of NH_(3)^(+)HCN for both coal and biomass,which causes more fuel-N to convert into tar-N and N_(2)-*** the blends of PL coal and wheat straw,the copyrolysis synergistic effect of coal/biomass influences the selectivity of HCN and NH_(3).The copyrolysis synergistic effect favors the formation of copyrolyzed HCN but has an opposite impact on the transformation from fuel-N to NH_(3).The synergistic effect of coal/biomass promotes the overall nitrogen conversion rate of NH_(3)^(+)HCN under a CO_(2)atmosphere,and the overall nitrogen conversion rate of NH_(3)+HCN is suppressed under an argon atmosphere,*** addition,the synergistic effect of coal/biomass suppresses the yield of environmentally harmless N_2,and more fuel-N was retained in the char.

关键词： Pyrolysis coal/biomass nitrogen NH_3 HCN

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Time-scheduled observer design for switched linear systems with unknown inputs

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Science China(Information Sciences) 2022年第7期65卷 265-266页

作者： Shuang SHI zhongyang FEI Xudong ZHAO College of Automation Engineering Nanjing University of Aeronautics and Astronautics Key Laboratory of Intelligent Control and Optimization for Industrial Equipment of Ministry of Education Dalian University of Technology

Dear editor, Since uncertain disturbance, actuator faults and unmodeled dynamics can all be viewed as unknown inputs in various practical systems, the issue of unknown input observer design is of great significance. Meanwhile, switched systems have attracted extensive attention, which are prevailingly motivated by superior capabilities in modeling numerous practical systems possessing switching characteristics. Recently, the state observation for switched systems with unknown inputs has attracted considerable attention [1–5].

关键词： switched linear systems unknown inputs admissible edge-dependent average dwell-time multiple discontinuous Lyapunov-like functions observer design

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Charactering and optimizing cathode electrolytes interface for advanced rechargeable batteries:Promises and challenges

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Green Energy & Environment 2022年第4期7卷 606-635页

作者： zhongyang Zhang Xinran Wang Ying Bai Chuan Wu Beijing Key Laboratory of Environmental Science and Engineering School of Materials Science&EngineeringBeijing Institute of TechnologyBeijingChina Yangtze Delta Region Academy of Beijing Institute of Technology Jiaxing314019China

With the advancement of secondary batteries,interfacial properties of electrode materials have been recognized as essential factors to their electrochemical ***,the majority of investigations are devoted into advanced electrode materials synthesis,while there is insufficient attention paid to regulate their *** this regard,the solid electrolyte interphase(SEI)at anode part has been studied for 40 years,already achieving remarkable outcomes on improving the stability of anode ***,the study on the cathode electrolyte interfaces(CEI)remains in infancy,which constitutes a potential restriction to the capacity contribution,stability and safety of *** fact,the native CEI generally possesses unfavorable characteristics against structural and compositional stability that requires demanding optimization ***,an in-depth understanding of the CEI is of great significance to guide the optimization principles in terms of composition,structure,growth mechanism,and electrochemical *** this literature,recent progress and advances of the CEI characterization methods and optimization protocols are summarized,and meanwhile the mutually-reinforced mechanisms between detection and modification are *** criteria and the potential development of the CEI characterization are proposed with insights of novel optimization directions.

关键词： Cathode electrolyte interface Secondary battery Characterization methods In situ/operando Synchrotron radiation

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