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Meta-analysis of transarterial chemoembolization combined with cryoablation vs transarterial chemoembolization alone for≥5 cm hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2793-2803页

作者： Jie-Fei Cheng Qiu-Lian Sun Ling Tang xin-Jian Xu Xiang-zhong Huang Department of Radiology The Fifth People’s Hospital of TaizhouTaizhou 225300Jiangsu ProvinceChina Department of Radiology The Fifth People’s Hospital of SuzhouSuzhou 215100Jiangsu ProvinceChina Department of Radiology The Fourth People’s Hospital of TaizhouTaizhou 225300Jiangsu ProvinceChina Department of Interventional Radiology Jiangyin People HospitalJiangyin 214400Jiangsu ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)ranks sixth globally in cancer incidence and third in mortality ***,over 70% of HCC patients forego the opportunity for curative surgery or liver transplantation due to inadequate physical examinations,poor physical condition,and limited organ availability upon *** guidelines endorse transarterial chemoembolization(TACE)as the frontline treatment for intermediate to advanced-stage ***(CRA)is an emerging local ablative therapy increasingly used in HCC *** studies suggest that combining CRA with TACE offers complementary and synergistic effects,potentially improving long-term survival ***,the superiority of combined TACE+CRA therapy over TACE alone for HCC lesions equal to or exceeding 5 cm requires further *** To compare the efficacy and safety of TACE combined with CRA vs TACE alone in the treatment of HCC with a diameter of≥5 *** PubMed,EMBASE,Cochrane Library,CNKI,Wanfang,and VIP databases were searched to retrieve all relevant studies on TACE and CRA up to July ***-analysis was performed using RevMan 5.3 *** After screening according to the inclusion and exclusion criteria,6 articles were included,including 2 randomized controlled trials and 4 nonrandomized controlled trials,with a total of 575 patients included in the *** results showed that the objective response rate[odds ratio(OR)=2.56,95%confidence interval(CI):1.66-3.96,P<0.0001],disease control rate(OR=3.03,95%CI:1.88-4.89,P<0.00001),1-year survival rate(OR=3.79,95%CI:2.50-5.76,P<0.00001),2-year survival rate(OR=2.34,95%CI:1.43-3.85,P=0.0008),and 3-year survival rate(OR=3.34,95%CI:1.61-6.94,P=0.001)were all superior to those of the control group;the postoperative decrease in alpha-fetoprotein value(OR=295.53,95%CI:250.22-340.85,P<0.0001),the postoperative increase in CD4 value(OR=10.59,95%CI:8.78-12.40,P<0.00001),and the postoperative decrease in

关键词： Hepatic cancer Cryoablation Chemoembolization Transarterial chemoembolization Meta analysis

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Dimethylamine oxalate manipulating CsPbI_(3) perovskite film crystallization process for high efficiency carbon electrode based perovskite solar cells

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Journal of Energy Chemistry 2024年第6期93卷 221-228,I0006页

作者： Wenran Wang xin Peng Jianxin Zhang Jiage Lin Rong Huang Guizhi Zhang Huishi Guo Zhenxiao Pan xinhua zhong Huashang Rao Key Laboratory for Biobased Materials and Energy of Ministry of Education College of Materials and EnergySouth China Agricultural UniversityGuangzhou 510642GuangdongChina College of Chemistry and Civil Engineering Shaoguan UniversityShaoguan 512005GuangdongChina Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region Shaoguan UniversityShaoguan 512005GuangdongChina

Crystallization process determines the quality of perovskite films and the performances of resultant perovskite solar cells(PSCs).Dimethylamine oxalate has been proven as a multifunctional modulator,and is explored as an efficient additive in manipulating the crystallization process of CsPbI_(3) perovskite *** one hand,oxalate serves as the precipitator that facilitates the nucleation process of *** larger size of intermediate is conductive to the larger size and smaller grain boundaries of resultant *** the other hand,in subsequent annealing process,the phase conversion and growth process of transient perovskite can be decelerated due to the strong interactions of oxalate with both dimethylamine cation(DMA^(+))and Pb^(2+).Due to the optimized crystallization kinetics,the morphology and quality of CsPbI_(3) perovskite films are comprehensively improved with lower defect concentrations,and charge recombination loss is effectively *** from the optimized crystal quality of perovskite films,the carbon electrode-based CsPbI_(3) PSCs exhibit a champion efficiency of 18.48%.This represents one of the highest levels among all hole transport layer-free inorganic perovskite solar cells.

关键词： Solar cells Perovskite CsPbI_(3) Carbon electrodes Oxalate

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Clathrate metal superhydrides under high-pressure conditions: enroute to room-temperature superconductivity

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National Science Review 2024年第07期 33-46页

作者： Ying Sun xin zhong Hanyu Liu Yanming Ma Key Laboratory of Material Simulation Methods&Software of Ministry of Education College of Physics Jilin University State Key Laboratory of Superhard Materials College of PhysicsJilin University International Center of Future Science Jilin University

Room-temperature superconductivity has been a long-held dream of mankind and a focus of considerable interest in the research field of superconductivity. Significant progress has recently been achieved in hydrogen-based superconductors found in superhydrides（hydrides with unexpectedly high hydrogen contents） that are stabilized under high-pressure conditions and are not capturable at ambient *** particular interest is the discovery of a class of best-ever-known superconductors in clathrate metal superhydrides that hold the record for high superconductivity(e.g. Tc= 250–260 K for LaH10) among known superconductors and have great promise to be those that realize the long-sought room-temperature superconductivity. In these peculiar clathrate superhydrides, hydrogen forms unusual ‘clathrate’ cages containing encaged metal atoms, of which such a kind was first reported in a calcium hexa-superhydride（CaH6） showing a measured high Tcof 215 K under a pressure of 170 GPa. In this review, we aim to offer an overview of the current status of research progress on the clathrate metal superhydride superconductors,discuss the superconducting mechanism and highlight the key features（e.g. structure motifs, bonding features, electronic structure, etc.） that govern the high-temperature superconductivity. Future research direction along this line to find room-temperature superconductors will be discussed.

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Highly coupled off-resonance lattice design in diffraction-limited light sources

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Nuclear Science and Techniques 2024年第9期35卷 92-102页

作者： Yi-Hao Gong Shun-Qiang Tian xin-zhong Liu Shou-Zhi Xuan Li-Yuan Tan Ling-Long Mao Shanghai Advanced Research Institute Chinese Academy of Sciences Shanghai 201204 ShanghaiChina Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201800 ShanghaiChina University of Chinese Academy of Sciences 100049 BeijingChina

The round-beam operation presents many benefits for scientific experiments regarding synchrotron radiation and the weak-ening influences of intra-beam scattering in diffraction-limited synchrotron light sources.A round-beam generation method based on the global setting of skew quadrupoles and the application of a non-dominated sorting genetic algorithm was pro-posed in this *** schemes,including large-emittance coupling introduced via betatron coupling and vertical disper-sion,were explored in a candidate lattice for an upgrade-proposal of the Shanghai synchrotron radiation *** variations with lattice imperfections and their influence on the beam dynamics of beam optic distortions were *** results demonstrated that a precise coupling control ranging from 10 to 100%was achieved under low optical distortion,whereas full-coupling generation and its robustness were achieved by our proposed method by adjusting the skew quadrupole components located in the dispersion-free *** Touschek lifetime increased by a factor of 2–2.5.

关键词： Diffraction-limited storage ring(DLSR) Shanghai synchrotron radiation facility upgrade(SSRF-U) Round beam Off-resonance coupling

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Research status and perspectives of MXene-based materials for aqueous zinc-ion batteries

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Rare Metals 2024年第5期43卷 1867-1885页

作者： Xiao-Yu Wang Qi-Hang Yang xin-Yan Meng Meng-Meng Zhen Zhen-zhong Hu Bo-Xiong Shen School of Energy and Environmental Engineering Hebei University of TechnologyTianjin 300071China

Aqueous zinc-ion batteries(AZIBs)as green battery systems have attracted widespread attention in large-scale electrochemical energy storage devices,owing to their high safety,abundant Zn materials,high theoretica specific capacity and low redox *** there are some thorny issues in AZIBs that hinder their practical application,such as low intrinsic electron conductivity,slow ion migration kinetics,zinc dendrites and side ***-based materials with superior conductivity,large polar surface and abundant active sites can simultaneously serve as cathode materials,electrolyte additive and protection layer of anode to regulate redox reactions of *** various materials have been used to improve electrochemical performances of AZIBs there is a lack of in-depth discussion on the regulation mechanism of MXene-based materials for *** this review,we elaborate the research progress of MXenebased materials in AZIBs,including their application in cathode materials and inhibition of zinc *** the future prospects and development directions of MXenebased materials that may improve performance of AZIBs are prospected.

关键词： MXene Aqueous zinc-ion batteries Composite materials Zinc dendrites

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A general climatology of categorized Martian ionospheric irregularities

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Science China Earth Sciences 2024年第10期67卷 3302-3325页

作者： xin WAN Jiahao zhong Yongqiang HAO Chao XIONG Hui WANG Yutian CAO Jun CUI Yiwen LIU Qiaoling LI Jiawei KUAI Planetary Environmental and Astrobiological Research Laboratory(PEARL) School of Atmospheric SciencesSun Yat-sen UniversityZhuhai 519082China Key Laboratory of Tropical Atmosphere-Ocean System Ministry of EducationZhuhai 519082China Department of Space Physics College of Electronic InformationLuojia LaboratoryWuhan UniversityWuhan 430079China School of Physics and Electronic Information Shangrao Normal UniversityShangrao 334001China School of Petroleum China University of Petroleum-Beijing at KaramayKaramay 834000China College of Astronautics Nanjing University of Aeronautics and AstronauticsNanjing 210016China

A climatological survey of Martian ionospheric plasma density irregularities was conducted by exploring the in-situ measurements of the Mars Atmosphere and Volatile EvolutioN(MAVEN) spacecraft. The irregularities were first classified as enhancement, depletion, and oscillation. By checking the simultaneous magnetic field fluctuation, the irregularities have been classified into two types: with or without magnetic signatures. The classified irregularities exhibit diverse global occurrence patterns, as those with magnetic signatures tend to appear near the periphery of the crustal magnetic anomaly(MA), and those without magnetic signatures prefer to appear either inside of the MA or outside of the MA, depending on the type and solar zenith angle. Under most circumstances, the irregularities have a considerable occurrence rate at altitudes above the ionospheric dynamo height(above 200 km), and the magnetization state of the ions seems irrelevant to their occurrence. In addition, the irregularities do not show dependence on magnetic field geometry, except that the enhancement without magnetic signatures favors the vertical field line, implying its equivalence to the localized bulge. Other similarities and discrepancies exist in reference to previous studies. We believe this global survey complements previous research and provides crucial research clues for future efforts to clarify the nature of the Martian ionospheric irregularities.

关键词： Mars MAVEN Ionosphere Ionospheric irregularities Crustal magnetic anomaly Plasma

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Constructing oxygen deficiency-rich V_(2)O_(3)@PEDOT cathode for high-performance aqueous zinc-ion batteries

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Rare Metals 2024年第2期43卷 635-646页

作者： Dong-Fei Sun Zi-Juan Wang Tian Tian xin Yu Dan-Dan Yu Xiao-zhong Zhou Guo-Fu Ma Zi-Qiang Lei Key Laboratory of Eco-functional Polymer Materials of the Ministry of Education Key Laboratory of Eco-environmental Polymer Materials of Gansu ProvinceSchool of College of Chemistry and Chemical EngineeringNorthwest Normal UniversityLanzhou730070China

Aqueous zinc-ion batteries(AZIBs)have attracted widespread attention due to the advantages of high safety and environmental *** V_(2)O_(3) is a promising cathode,the strong electrostatic interaction between Zn^(2+) and V_(2)O_(3) crystal,and the sluggish reaction kinetics still limit their application in ***,the oxygen defects rich V_(2)O_(3) with conducive poly(3,4-ethylenedioxythiophene)(PEDOT)shell(V_(2)O_(3)-Od@PEDOT)was fabricated for AZIBs by combining the sulfur-assisted thermal reduction and in-situ polymerization *** introduced oxygen vacancies of V_(2)O_(3)–Od@PEDOT weaken the electrostatic interaction between Zn^(2+) and the host material,improving the interfacial electron transport,while the PEDOT coating enhances the structural stability and conductivity of V_(2)O_(3),thus accelerating the reaction *** on the advantages,V_(2)O_(3)–Od@PEDOT electrode delivers a reversible capacity of 495 mAh·g^(−1) at 0.1 A·g^(−1),good rate capability(189 mAh·g^(−1)at 8.0 A·g^(−1)),and an impressive cycling stability with 90.1%capacity retention over 1000 cycles at 8.0 A·g^(−1).The strategy may provide a path for exploiting the other materials for high performance AZIBs.

关键词： Oxygen defects V_(2)O_(3) PEDOT Electrochemical self-optimization Aqueous zinc-ion batteries

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Intrahepatic portal venous systems in adult patients with cavernous transformation of portal vein: Imaging features and a new classification

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Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 481-486页

作者： xin Huang Qian Lu Yue-Wei Zhang Lin Zhang Zhi-zhong Ren Xiao-Wei Yang Ying Liu Rui Tang Hepatopancreatobiliary Center Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing 102218China

Background: Cavernous transformation of the portal vein(CTPV) due to portal vein obstruction is a rare vascular anomaly defined as the formation of multiple collateral vessels in the hepatic hilum. This study aimed to investigate the imaging features of intrahepatic portal vein in adult patients with CTPV and establish the relationship between the manifestations of intrahepatic portal vein and the progression of CTPV. Methods: We retrospectively analyzed 14 CTPV patients in Beijing Tsinghua Changgung Hospital. All patients underwent both direct portal venography(DPV) and computed tomography angiography(CTA) to reveal the manifestations of the portal venous system. The vessels measured included the left portal vein(LPV), right portal vein(RPV), main portal vein(MPV) and the portal vein bifurcation(PVB). Results: Nine males and 5 females, with a median age of 40.5 years, were included in the study. No significant difference was found in the diameters of the LPV or RPV measured by DPV and CTA. The visualization in terms of LPV, RPV and PVB measured by DPV was higher than that by CTA. There was a significant association between LPV/RPV and PVB/MPV in term of visibility revealed with DPV( P = 0.01), while this association was not observed with CTA. According to the imaging features of the portal vein measured by DPV, CTPV was classified into three categories to facilitate the diagnosis and treatment. Conclusions: DPV was more accurate than CTA for revealing the course of the intrahepatic portal vein in patients with CTPV. The classification of CTPV, that originated from the imaging features of the portal vein revealed by DPV, may provide a new perspective for the diagnosis and treatment of CTPV.

关键词： Cavernous transformation of the portal vein Classification Direct portal venography Intrahepatic portal venous system

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Rice stripe mosaic virus hijacks rice heading‐related gene to promote the overwintering of its insect vector

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Journal of Integrative Plant Biology 2024年第9期66卷 2000-2016页

作者： Siping Chen xinyi zhong Zhiyi Wang Biao Chen Xiuqin Huang Sipei Xu xin Yang Guohui Zhou Tong Zhang Guangdong Province Key Laboratory of Microbial Signals and Disease Control College of Plant ProtectionSouth China Agricultural UniversityGuangzhou 510642China State Key Laboratory of Green Pesticide South China Agricultural UniversityGuangzhou 510642China

Rice stripe mosaic virus(RSMV)is an emerging pathogen which significantly reduces rice yields in the southern region of *** is transmitted by the leafhopper Recilia dorsalis,which overwinters in rice *** field investigations revealed that RSMV infection causes delayed rice heading,resulting in a large number of green diseased plants remaining in winter rice *** creates a favorable environment for leafhoppers and viruses to overwinter,potentially contributing to the rapid spread and epidemic of the ***,we explored the mechanism by which RSMV manipulates the developmental processes of the rice plant.A rice heading‐related E3 ubiquitin ligase,Heading date Associated Factor 1(HAF1),was found to be hijacked by the RSMV‐encoded *** impairment of HAF1 function affects the ubiquitination and degradation of downstream proteins,HEADING DATE 1 and EARLY FLOWERING3,leading to a delay in rice *** results provide new insights into the development regulation‐based molecular interactions between virus and plant,and highlights the importance of understanding virus‐vector‐plant tripartite interactions for effective disease management strategies.

关键词： HAF1 heading leafhoppers overwintering RSMV

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Study on the occurrence and influencing factors of gastrointestinal symptoms in hemodialysis patients with uremia

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2157-2166页

作者： Dan Yuan Xiao-Qi Wang Feng Shao Jing-Jing Zhou zhong-xin Li Department of Nephrology Beijing Luhe Hospital Affiliated to Capital Medical UniversityBeijing 101100China

BACKGROUND Gastrointestinal symptoms are common in patients with uremia undergoing hemodialysis,and these symptoms seriously affect patients'*** To assess the occurrence and factors influencing gastrointestinal symptoms in patients with uremia undergoing *** We retrospectively selected 98 patients with uremia who underwent regular hemo-dialysis treatment in the blood purification center of our hospital from December 2022 to December *** gastrointestinal symptoms and scores of each dimension were evaluated using the Gastrointestinal Symptom Grading Scale(GSRS).Patients were divided into gastrointestinal symptoms and no gastrointestinal symptom groups according to whether they had gastrointestinal *** factors that may affect gastrointestinal symptoms were identified by single-factor *** logistic regression analysis was performed to identify independent risk factors for gastrointestinal *** Gastrointestinal symptoms included indigestion,constipation,reflux,diarrhea,abdominal pain,and eating disorders,and the total average GSRS score was 1.35±*** study showed that age,number of tablets,dialysis time,glucocorticoid,parathyroid hormone(PTH),combined diabetes mellitus and C-reactive protein(CRP)were independent risk factors for gastrointestinal symptoms in patients with uremia undergoing hemodialysis,whereas body mass index(BMI),hemoglobin(Hb),and urea clearance index were independent protective factors(P<0.05).CONCLUSION Gastrointestinal symptoms are mostly mild in patients with uremia undergoing hemodialysis,most commonly including dyspepsia,eating disorders,and gastroesophageal *** independent influencing factors mainly include the BMI,age,number of pills taken,dialysis time,urea clearance index,Hb,use of glucocorticoids,and thyroid hormone ***,CRP,and diabetes are clinically related factors influencing the occurrence of gastrointestinal symptoms,and targeted prevention can be perform

关键词： Uremic hemodialysis Gastrointestinal symptoms Influencing factors Blood pressure dialysis Chronic renal failure

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