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Coupling Effect of Morphology and Mechanical Properties Contributes to the Tribological Behaviors of Snake Scales

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Journal of Bionic Engineering 2018年第3期15卷 481-493页

作者： Long Zheng yinghui zhong Yihang Gao Jiayi Li Zhihui Zhang Zhenning Liu Luquan Ren Key Laboratory of Bionic Engineering (Ministry of Education) College of Biological and Agricultural Engineering Jilin University Changchun 130022 China

It is known that the tribological behaviors of snake skins are contributed by the synergistic action of multiple factors, such as surface morphology and mechanical properties, which has inspired fabrication of scale-like surface textures in recent years. However, the coupling effect and mechanism remain to be elucidated. In this work, the morphology and mechanical properties of the scales from different body sections （leading body half, middle trunk and tailing body half） and positions （dorsal, lateral and ventral） of Boa constrictor and Eryx tataricus were characterized and compared to investigate the corresponding effects on the tribological behaviors and to probe the possible coupling mechanism. The morphological characterizations of scanning electron microscopy and atomic force microscopy revealed sig- nificant differences between the two species that the scales from Boa constrictor are rougher in general. The mechanical properties measured by nanoindentation corroboratively demonstrated substantial differences in elastic modulus and hardness. Interestingly, the ventral scales with lower surface roughness, together with relatively larger elastic modulus and hardness, manifest higher friction coefficients. A ＂double-crossed＂ hypothesis was proposed to explain the observed coupling effect of morphology and mechanical properties on friction, which may afford valuable insights for the design of bionic surface with desirable tribological performance.

关键词： bionics coupling effect friction coefficient morphology mechanical properties snake scales

T-Gate Fabrication of InP-Based HEMTs Using PMGI/ZEP520A/PMGI/ZEP520A Stacked Resist

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Chinese Journal of Electronics 2016年第3期25卷 448-452页

作者： zhong yinghui ZANG Huaping WANG Haili SUN Shuxiang LI Kaikai DING Peng JIN Zhi School of Physics and Engineering Zhengzhou University Institute of Microelectronics Chinese Academy of Sciences

PMGI/ZEP520A/PMGI/ZEP520 A fourlayer resist stack is firstly proposed for T-gates fabrication of InP-based High electron mobility transistors(HEMTs).Gate-head and gate-foot are exposed in single-step Electron beam lithography(EBL), which avoids alignment deviation by automatic self-alignment. The newly introduced PMGI at the bottom greatly improves the adhesiveness of ZEP520 A resist with the substrate. The optimal gate-foot length reaches 101 nm for a design of 50 nm gate footprint pattern, and which can be improved to be 66.8nm for 30 nm gate footprint pattern. Finally, Tgates in nanometer regime have been successfully incorporated into InP-based HEMTs fabrication. Benefiting from both the narrow gate-foot and the reduced parasitic gatecapacitance by single-step EBL technique with the fourlayer resist stack, the fabricated devices with gate-foot length of 101 nm demonstrate excellent DC and RF performances: the maximum extrinsic transconductance, the current-gain cutoff frequency and maximum oscillation frequency are 1051 m S/mm, 249 GHz and 415 GHz, respectively.

关键词： T-gate High electron mobility transistors(HEMTs) InP ZEP520A Electron beam lithography(EBL)

Comparison of Single-Step and Two-Step EBL T-Gates Fabrication Techniques for In P-Based HEMT

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Chinese Journal of Electronics 2016年第2期25卷 199-202页

作者： zhong yinghui ZANG Huaping SUN Shuxiang WANG Haili LI Kaikai LI Xinjian DING Peng JIN Zhi School of Physics and Engineering Zhengzhou University Institute of Microelectronics Chinese Academy of Sciences

T-Gate fabrication processes for In P-based High electron mobility transistors(HEMTs) are described using PMMA/Al/UVIII. The single-step and two-step Electron beam lithography(EBL) methods are proposed contrastively without dielectric support layer. The optimal gate-foot length is 196 nm for 50 nm geometry path by single-step EBL technique. Since the gate-foot and gate-head are defined independently, the two-step EBL process minimizes forward scattering and enables smaller gate-foot length, which improves to be 141 nm for 50 nm geometry path and also 88 nm for 30 nm geometry *** EBL methods have been incorporated into In Pbased HEMTs fabrication. With the gate-foot length decreases from 196 nm to 141 nm, the current-gain cutoff frequency(fT) is improved from 125 GHz to 164 GHz, and also the maximum oscillation frequency(fmax) increases from305 GHz to 375 GHz.

关键词： T-Gate HEMTs EBL technique Two-step EBL technique Polymethylmethacrylate(PMMA)

Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury

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Neural Regeneration Research 2017年第5期12卷 702-713页

作者： Robert B.Shultz yinghui zhong School of Biomedical Engineering Science and Health Systems Drexel University Philadelphia PA USA

Minocycline hydrochloride（MH）, a semi-synthetic tetracycline derivative, is a clinically available antibiotic and anti-inflammatory drug that also exhibits potent neuroprotective activities. It has been shown to target multiple secondary injury mechanisms in spinal cord injury, via its anti-inflammatory, anti-oxidant, and anti-apoptotic properties. The secondary injury mechanisms that MH can potentially target include inflammation, free radicals and oxidative stress, glutamate excitotoxicity, calcium influx, mitochondrial dysfunction, ischemia, hemorrhage, and edema. This review discusses the potential mechanisms of the multifaceted actions of MH. Its anti-inflammatory and neuroprotective effects are partially achieved through conserved mechanisms such as modulation of p38 mitogen-activated protein kinase（MAPK） and phosphoinositide 3-kinase（PI3K）/Akt signaling pathways as well as inhibition of matrix metalloproteinases（MMPs）. Additionally, MH can directly inhibit calcium influx through the N-methyl-D-aspartate（NMDA） receptors, mitochondrial calcium uptake, poly（ADP-ribose） polymerase-1（PARP-1） enzymatic activity, and iron toxicity. It can also directly scavenge free radicals. Because it can target many secondary injury mechanisms, MH treatment holds great promise for reducing tissue damage and promoting functional recovery following spinal cord injury.

关键词： minocycline inflammation anti-oxidant neuroprotection oxidative stress glutamate exitotoxicity cytochrome c P38 MAPK PI3K/Akt calcium influx

Core-shell SERS Probe for Trace Arsenate Detection

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Core-shell SERS Probe for Trace Arsenate Detection

InAlAs/InGaAs/InAlAs量子阱质子辐照损伤机理

第十五届全国光化学学术讨论会

作者： Shan Zeng Jing Ding yinghui zhong Hang Sun Key Laboratory of Bionic Engineering (Ministry of Education) College of Biological and Agricultural Engineering Jilin University

A prerequisite for improving the safety of drinking water is to develop an effective and reliable method for the detection of trace toxic heavy metal ions. How to increase the adsorption of ions on Surface-Enhanced Raman Scattering(SERS) active substrate is an issue to reduce the SERS detection limit. FeO nanoparticles show excellent performance and can also be activated and regenerated through

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西安电子科技大学学报 2017年第4期44卷 151-155,161页

作者：王海丽吉慧芳孙树祥丁芃金智魏志超钟英辉李玉晓郑州大学物理工程学院河南郑州450001 中国科学院微电子研究所北京100029 中国空间技术研究院北京100086

对InP基高电子迁移率场效晶体管关键的InAlAs/InGaAs/InAlAs量子阱结构质子辐照损伤机理进行了研究.基于SRIM软件计算了50keV、75keV和200keV质子在量子阱中的投影射程和诱生空位缺陷信息.随着质子能量增加,质子注入深度逐渐增加并最终... 详细信息

对InP基高电子迁移率场效晶体管关键的InAlAs/InGaAs/InAlAs量子阱结构质子辐照损伤机理进行了研究.基于SRIM软件计算了50keV、75keV和200keV质子在量子阱中的投影射程和诱生空位缺陷信息.随着质子能量增加,质子注入深度逐渐增加并最终逃逸出材料层.另外,在异质结附近诱生的空位缺陷个数先增加后减小,且As空位为主要的诱生缺陷.基于解析模型计算了不同能量质子入射下In_(0.52)Al_(0.48)As和In_(0.53)Ga_(0.47)As材料的非电离能量损失.随着质子能量增加,非电离能量损失先增加后减小,与辐照诱生缺陷密度随能量的变化趋势一致.最后通过辐照陷阱模型验证了诱生缺陷作为受主补偿中心对量子阱二维电子气的俘获作用,确定了非电离能量损失诱生空位缺陷为质子辐照主要的损伤机制.

关键词：高电子迁移率晶体管质子辐照空位缺陷非电离能量损失

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基于几何推理的创意平板折叠桌参数设计

湖南工业大学学报 2015年第4期29卷 76-79页

作者：包贤敬钟云飞钟颖慧黄志文湖南工业大学包装与材料工程学院湖南株洲412007

以创意平板折叠桌的折叠结构基本参数为切入点,运用几何推理及多目标约束求解方法,建立目标函数和约束条件,得到平板折叠桌的最优加工参数,并采用力矩平衡原理,实验验证了该最优加工参数下的折叠桌稳定性能。实验结果表明:当折叠桌的最... 详细信息

以创意平板折叠桌的折叠结构基本参数为切入点,运用几何推理及多目标约束求解方法,建立目标函数和约束条件,得到平板折叠桌的最优加工参数,并采用力矩平衡原理,实验验证了该最优加工参数下的折叠桌稳定性能。实验结果表明:当折叠桌的最外侧桌腿与中间桌腿构成的异面三角形为正三角形时,平板折叠桌的稳定性能最好。

关键词：折叠结构几何推理参数设计稳定性能

基于Multisim的负反馈放大电路动态参数仿真分析

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通信电源技术 2021年第3期38卷 42-43,46页

作者：杨洁谷肖飞路书祥钟英辉郑州大学物理学院(微电子学院) 河南郑州450001

模拟电子技术课程是一门偏向于应用类的电子专业基础课,教学内容较多且难度较大。随着Multisim软件的应用,很好地弥补了传统实验课程的不足,教师可以在讲课过程中实时演示实验。因此任课教师需要设计基于Multisim的实验内容来满足教学... 详细信息

模拟电子技术课程是一门偏向于应用类的电子专业基础课,教学内容较多且难度较大。随着Multisim软件的应用,很好地弥补了传统实验课程的不足,教师可以在讲课过程中实时演示实验。因此任课教师需要设计基于Multisim的实验内容来满足教学要求。以负反馈放大电路为例,阐述了负反馈放大电路动态参数的仿真测量,并验证了负反馈对动态参数性能的影响。

关键词：模拟电子技术 Multisim 负反馈放大电路

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COMT基因与青少年抑郁症关系的研究进展

当代医药论丛 2023年第15期21卷 63-67页

作者：赵雨生刘芳钟英慧林志雄林举达广东医科大学广东湛江524000 广东医科大学附属医院精神心理科广东湛江524000

抑郁症是最常见的精神障碍,也是造成全球年轻人疾病负担的主要原因。青春期是童年和成年之间的发育过渡期,身体和大脑及生物系统发生显著变化,抑郁症经常出现在青春期,成为威胁青少年身心健康乃至生命的重要问题。但这种疾病的病理生理... 详细信息

抑郁症是最常见的精神障碍,也是造成全球年轻人疾病负担的主要原因。青春期是童年和成年之间的发育过渡期,身体和大脑及生物系统发生显著变化,抑郁症经常出现在青春期,成为威胁青少年身心健康乃至生命的重要问题。但这种疾病的病理生理学仍不清楚,根据当前药物治疗所依据的单胺假说,抑郁症是由大脑中的单胺(血清素、多巴胺、去甲肾上腺素)神经传递系统功能障碍引起的。其中多巴胺基因系统中的儿茶酚-O-甲基转移酶(COMT)基因可参与降解多巴胺、去甲肾上腺素和肾上腺素,且随着发育而发生变化,进而参与到青少年抑郁症的发生发展中。

关键词：抑郁症 COMT 基因多态性多巴胺