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World Journal of Gastroenterology 2024年第14期30卷 2059-2067页

作者： Jun Liu Peng Wang Li-Mei Wang Jing Guo ning zhong Department of Gastroenterology Qilu Hospital of Shandong UniversityJinan 250012Shandong ProvinceChina

BACKGROUND Hemorrhage associated with varices at the site of choledochojejunostomy is an unusual,difficult to treat,and often fatal manifestation of portal *** far,no treatment guidelines have been *** SUMMARY We reported three patients with jejunal varices at the site of choledochojejun-ostomy managed by endoscopic sclerotherapy with lauromacrogol/α-butyl cyanoacrylate injection at our institution between June 2021 and August *** reviewed all patient records,clinical presentation,endoscopic findings and treatment,outcomes and *** patients who underwent pancre-aticoduodenectomy with a Whipple anastomosis were examined using conven-tional upper gastrointestinal endoscopy for suspected hemorrhage from the afferent jejunal *** with stigmata of recent hemorrhage or active he-morrhage were observed around the choledochojejunostomy site in all three *** injection of lauromacrogol/α-butyl cyanoacrylate was carried out at jejunal varices for all three *** bleeding ceased and patency was observed for 26 and 2 months in two *** one patient with multiorgan failure and internal environment disturbance,rebleeding occurred 1 month after endoscopic sclerotherapy,and despite a second endoscopic sclero-therapy,repeated episodes of bleeding and multiorgan failure resulted in eventual *** We conclude that endoscopic sclerotherapy with lauromacrogol/α-butyl cyanoac-rylate injection can be an easy,effective,safe and low-cost treatment option for jejunal varicose bleeding at the site of choledochojejunostomy.

关键词： Endoscopic sclerotherapy Jejunal varices Choledochojejunostomy Portal vein hypertension Case report

High-resolution remote thermometry based on Bi^(3+)-doped 0D zinc halide hybrids

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Science China Chemistry 2024年第8期67卷 2599-2605页

作者： Cui-Mi Shi Shu-Hua Xue Jin-Yun Wang Liang-Jin Xu zhong-ning Chen State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China Fujian Science Technology Innovation Laboratory for Optoelectronic Information of ChinaFuzhou 350108China University of Chinese Academy of Sciences Beijing 100049China

Developing highly sensitive optical thermometers is of great significance due to their capability to enable remote and non-contact temperature measurements, rendering them highly applicable in diverse and harsh environments. Herein we report a temperature-dependent phosphor of 0D metal halide hybrid by incorporating Bi^(3+)into the(MePPh_(3))_(2)ZnCl_(4) matrix. Through Bi^(3+)doping,the initially non-luminescent(MePPh_(3))_(2) ZnCl_(4) matrix exhibits a deep-blue emission centered at 453 nm, with a photoluminescence quantum yield(PLQY) of 5.71% and a Stokes shift of 75 nm at room temperature. Experimental characterization demonstrates that exciton-like luminescence of Bi^(3+)is mainly responsible for the blue emission. Single crystals of Bi^(3+)-doped(MePPh_(3))_(2)ZnCl_(4) show an unusual correlation between photoluminescence(PL) lifetime and temperature. Particularly, the dependence of luminescence lifetime on temperature is most remarkable in the temperature range of 80 to 100 K with an exceptional sensitivity up to 0.09 K^(-1), representing one of the best levels for thermometry based on PL decay lifetime. Our work not only provides a viable strategy for designing a novel, environmentally friendly, and stable blue emitter, but also paves the way for precise thermometric application at low temperature.

关键词： lead-free hybrids Bi^(3+)doping blue emission temperature sensing

Characterization and spatial analysis of coseismic landslides triggered by the Luding Ms 6.8 earthquake in the Xianshuihe fault zone, Southwest China

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Journal of Mountain Science 2024年第1期21卷 160-181页

作者： GUO Changbao LI Caihong YANG Zhihua NI Jiawei zhong ning WANG Meng YAN Yiqiu SONG Deguang ZHANG Yanan ZHANG Xianbing WU Ruian CAO Shichao SHAO Weiwei Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China Key Laboratory of Active Tectonics and Geological Safety Ministry of Natural ResourcesBeijing 100081China Research Center of Neotectonism and Crustal Stability China Geological SurveyBeijing 100081China School of Earth Sciences and Resources China University of GeosciencesBeijing 100083China Sichuan Institute of Geological Survey Chengdu 610081China

On September 5, 2022, a magnitude Ms 6.8 earthquake occurred along the Moxi fault in the southern part of the Xianshuihe fault zone located in the southeastern margin of the Tibetan Plateau,resulting in severe damage and substantial economic loss. In this study, we established a coseismic landslide database triggered by Luding Ms 6.8 earthquake, which includes 4794 landslides with a total area of 46.79 km^(2). The coseismic landslides primarily consisted of medium and small-sized landslides, characterized by shallow surface sliding. Some exhibited characteristics of high-position initiation resulted in the obstruction or partial obstruction of rivers, leading to the formation of dammed lakes. Our research found that the coseismic landslides were predominantly observed on slopes ranging from 30° to 50°, occurring at between 1000 m and 2500 m, with slope aspects varying from 90° to 180°. Landslides were also highly developed in granitic bodies that had experienced structural fracturing and strong-tomoderate weathering. Coseismic landslides concentrated within a 6 km range on both sides of the Xianshuihe and Daduhe fault zones. The area and number of coseismic landslides exhibited a negative correlation with the distance to fault lines, road networks, and river systems, as they were influenced by fault activity, road excavation, and river erosion. The coseismic landslides were mainly distributed in the southeastern region of the epicenter, exhibiting relatively concentrated patterns within the IX-degree zones such as Moxi Town, Wandong River basin, Detuo Town to Wanggangping Township. Our research findings provide important data on the coseismic landslides triggered by the Luding Ms 6.8 earthquake and reveal the spatial distribution patterns of these landslides. These findings can serve as important references for risk mitigation, reconstruction planning, and regional earthquake disaster research in the earthquake-affected area.

关键词： Luding earthquake Coseismic landslides Remote sensing interpretation Spatial distribution Xianshuihe fault Earthquake fault

High-resolution remote thermometry based on Bi-doped 0D zinc halide hybrids

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Science China Chemistry 2024年

作者： Cui-Mi Shi Shu-Hua Xue Jin-Yun Wang Liang-Jin Xu zhong-ning Chen State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China University of Chinese Academy of Sciences

Developing highly sensitive optical thermometers is of great significance due to their capability to enable remote and non-contact temperature measurements, rendering them highly applicable in diverse and harsh environments. Herein we report a temperature-dependent phosphor of 0D metal halide hybrid by incorporating Bi3+into the（MePPh3）2ZnCl4matrix. Through Bi3+doping,the initially non-luminescent（MePPh3）2ZnCl4matrix exhibits a deep-blue emission centered at 453 nm, with a photoluminescence quantum yield（PLQY） of 5.71% and a Stokes shift of 75 nm at room temperature. Experimental characterization demonstrates that exciton-like luminescence of Bi3+is mainly responsible for the blue emission. Single crystals of Bi3+-doped（MePPh3）2ZnCl4show an unusual correlation between photoluminescence（PL） lifetime and temperature. Particularly, the dependence of luminescence lifetime on temperature is most remarkable in the temperature range of 80 to 100 K with an exceptional sensitivity up to 0.09 K-1, representing one of the best levels for thermometry based on PL decay lifetime. Our work not only provides a viable strategy for designing a novel, environmentally friendly, and stable blue emitter, but also paves the way for precise thermometric application at low temperature.

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中国式现代化与铸牢中华民族共同体意识的契合互动

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中南民族大学学报（人文社会科学版） 2024年第5期44卷 43-52,218页

作者：杨丽王中凝新疆大学马克思主义学院新疆乌鲁木齐830046

中国式现代化与铸牢中华民族共同体意识在发展源流、根本遵循、生成方式和目标导向等方面具有高度契合性。在此基础上,二者构成双向互动的关系:一方面,中国式现代化为铸牢中华民族共同体意识提供发展基础、提升推进力度和提增工作效果,... 详细信息

中国式现代化与铸牢中华民族共同体意识在发展源流、根本遵循、生成方式和目标导向等方面具有高度契合性。在此基础上,二者构成双向互动的关系:一方面,中国式现代化为铸牢中华民族共同体意识提供发展基础、提升推进力度和提增工作效果,彰显其社会主义现代化的助推功效和独特优势;另一方面,铸牢中华民族共同体意识为推进中国式现代化集合了以物质性聚能和精神性聚能的结合为形态、以内在稳定性与外在辐射性的统一为特征、以共同目标引领与理想信念指引的兼顾为路径的支撑。二者契合互动、同向同行,共同推进中华民族复兴和人类文明进步的历史进程。

关键词：中国式现代化铸牢中华民族共同体意识两个结合

中药调控PI3K-AKT信号通路改善心房颤动研究进展

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中国中西医结合杂志 2024年第2期44卷 238-244页

作者：纪雅琼宁忠平上海中医药大学上海健康医学院上海201203 上海健康医学院附属周浦医院心血管内科上海201318

心房颤动(atrial fibrillation,AF)是由心房中异常的电活动模式取代正常窦性心律导致的室上性快速性心律失常[1]。AF的易感性与年龄[2]、高血压病[3]、糖尿病、肥胖[4]、睡眠呼吸暂停[5]以及遗传变异[6]具有高度密切性。AF发作次数的增... 详细信息

心房颤动(atrial fibrillation,AF)是由心房中异常的电活动模式取代正常窦性心律导致的室上性快速性心律失常[1]。AF的易感性与年龄[2]、高血压病[3]、糖尿病、肥胖[4]、睡眠呼吸暂停[5]以及遗传变异[6]具有高度密切性。AF发作次数的增加可以明显改变血流动力学,降低心功能[7]。2021年,Lancet的一项研究发现,AF患者发生缺血性中风的风险显著增加,近30%中风患者患有AF[8]。此外,AF还与全身血栓、心肌梗死(心梗)和心力衰竭(心衰)的风险增加相关[9]。

关键词：缺血性中风中风患者正常窦性心律心房颤动睡眠呼吸暂停 PI3K 血流动力学密切性

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岭南古籍文献出版的回顾与展望

岭南文史 2024年第3期 51-54页

作者：钟永宁不详

岭南古籍文献出版是岭南文化传播的重要手段,其发展深受传统文化观念和岭南地域文化意识影响。本文梳理岭南古籍文献出版发展历程,总结了其历史经验与不足,并对未来发展提出了一些建设性意见。主张立足岭南古籍文献资源优势,尊重已成出... 详细信息

岭南古籍文献出版是岭南文化传播的重要手段,其发展深受传统文化观念和岭南地域文化意识影响。本文梳理岭南古籍文献出版发展历程,总结了其历史经验与不足,并对未来发展提出了一些建设性意见。主张立足岭南古籍文献资源优势,尊重已成出版格局,在古籍深度整理出版、影印出版、普及利用和古籍整理促进上,创新思路和工作方式,提升岭南古籍文献出版的权威性、系统性及整体效率与规模,增强岭南文化的传播力。

关键词：岭南古籍文献出版回顾展望

DMI−LiNO3离子液体类似物室温电沉积钕铁硼薄膜

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Transactions of Nonferrous Metals Society of China 2024年第6期34卷 2034-2044页

作者：鲁小青刘爱民刘风国胡宪伟石忠宁东北大学多金属共生矿生态化冶金教育部重点实验室沈阳110819 东北大学冶金学院沈阳110819

研究1,3-二甲基-2-咪唑啉酮(DMI)−LiNO_(3)离子液体类似物在室温条件下电沉积钕铁硼薄膜的可行性和反应机理。结果表明,循环伏安曲线中−1.83 V(vs Ag)处的还原峰对应于Fe(II)被还原为金属Fe,−2.01 V(vs Ag)处的还原峰对应于B(III)被还原... 详细信息

研究1,3-二甲基-2-咪唑啉酮(DMI)−LiNO_(3)离子液体类似物在室温条件下电沉积钕铁硼薄膜的可行性和反应机理。结果表明,循环伏安曲线中−1.83 V(vs Ag)处的还原峰对应于Fe(II)被还原为金属Fe,−2.01 V(vs Ag)处的还原峰对应于B(III)被还原为B。Fe(II)和B(III)的电化学还原反应是受扩散控制的不可逆过程,313 K下Fe(II)和B(III)的扩散系数分别为3.03×10^(−6)和6.74×10^(−7) cm^(2)/s。此外,XRD分析表明,在DMI−LiNO_(3)−Nd(CF_(3)SO_(3))_(3)−FeCl_(2)−H_(3)BO_(3)体系中以铝为基底电沉积2 h的产物含有NdFe_(3)B_(3);SEM和EDS分析表明,阴极产物中Nd、Fe和B元素呈均匀分布;XPS分析表明,钨基底表面中Nd、Fe和B的质量分数分别为27.44%、27.90%和7.51%。

关键词：离子液体类似物电沉积钕铁硼薄膜循环伏安法

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骨关节炎软骨细胞衰老潜在生物标志物的筛选

中国矫形外科杂志 2024年第10期32卷 916-923页

作者：白贵文许世林王胜张仲宁郑州大学第二附属医院河南郑州450000

[目的]采用生物信息分析学方法,筛选骨关节炎(osteoarthritis,OA)软骨细胞衰老潜在生物标志物,为揭示OA的发生机制及探索新的治疗方法提供理论依据。[方法]从基因表达综合数据库(gene expression omnibus,GEO)获取OA软骨组织数据集,使用... 详细信息

[目的]采用生物信息分析学方法,筛选骨关节炎(osteoarthritis,OA)软骨细胞衰老潜在生物标志物,为揭示OA的发生机制及探索新的治疗方法提供理论依据。[方法]从基因表达综合数据库(gene expression omnibus,GEO)获取OA软骨组织数据集,使用RStudio软件筛选出差异表达基因(differentially expressed genes,DEGs),并进行富集分析,再将DEGs与SenMayo衰老基因集取交集获得Hub基因,并进行验证,最后用miRNet在线平台及Cytoscape软件构建竞争性内源性RNA(competing endogenous RNA,ceRNA)网络。[结果]数据集GSE169077和GSE114007经差异分析并取交集后共得到DEGs 272个;对DEGs行基因本体论(Gene Ontology,GO)分析,发现其主要富集在细胞外基质组织、细胞外结构组织等条目中;行京都基因与基因组百科全书(kyoto encyclopedia of genes and genomes,KEGG)分析,发现其主要富集在PI3K-Akt信号通路,黏着斑信号通路等;经筛选及验证,得到了2个Hub基因:IGF1和MMP2;构建ceRNA网络并筛选出3组RNA调控途径:KCNQ1OT1/XIST-hsa-mir-16-5p-IGF1,KCNQ1OT1/XIST-hsa-mir-424-5p-MMP2,KCNQ1OT1/XIST-hsa-mir-377-3p-IGF1/MMP2。[结论]IGF1和MMP2可作为OA软骨细胞衰老的Hub基因,KCNQ1OT1/XIST-hsa-mir-16-5p-IGF1,KCNQ1OT1/XIST-hsa-mir-424-5p-MMP2,KCNQ1OT1/XIST-hsa-mir-377-3p-IGF1/MMP2可能是调节OA软骨细胞衰老的潜在RNA调控途径。

关键词：骨关节炎软骨细胞衰老 SenMayo衰老基因集生物标志物 RNA调控途径生物信息学

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CGA专科护理结合家庭同步健康教育对老年冠心病患者应对方式及自我效能的影响

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中国医药指南 2024年第25期22卷 167-170页

作者：钟凝李树蕙厦门大学附属第一医院老年医学一科厦门36100

目的探究老年冠心病患者采用综合老年评估(comprehensive elderly assessment,CGA)专科护理结合家庭同步健康教育的应用效果。方法择取2022年1月至2023年12月本院100例老年冠心病患者作为研究对象,依据随机数字表法分组(对照组:常规护理... 详细信息

目的探究老年冠心病患者采用综合老年评估(comprehensive elderly assessment,CGA)专科护理结合家庭同步健康教育的应用效果。方法择取2022年1月至2023年12月本院100例老年冠心病患者作为研究对象,依据随机数字表法分组(对照组:常规护理,观察组:常规护理+CGA专科护理+家庭同步健康宣教),各组50例,对比两组医学应对方式问卷量表(MCMQ)、疾病认知度、自我效能评分、不良事件发生率、冠心病自我管理量表(CSMS)评分。结果两组MCMQ评估对比,观察组更优,观察组回避、屈服评分更低,且面对项评分更高(P<0.05)。观察组疾病认知度高于对照组(P<0.05)。干预后3个月,观察组自我效能评分、CSMS评分高于对照组,不良事件发生率低于对照组(均P<0.05)。结论在对老年冠心病患者干预时,CGA专科护理结合家庭同步健康教育可改善患者自我效能,促使应对方式改变,临床应用价值高。

关键词：老年冠心病家庭同步健康教育应对方式自我效能疾病认知度